Gene Page: PTTG1IP

Summary
GeneID  754
Symbol  PTTG1IP
Synonyms  C21orf1|C21orf3|PBF
Description  pituitary tumor-transforming 1 interacting protein
See related  HGNC:13524|MIM:603784|Ensembl:ENSG00000183255|HPRD:04807|
Locus tag  -
Gene type  protein-coding
Map location  21q22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.44 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SATB20.920.95
TSPAN140.910.86
SLA0.910.87
TMEM1080.900.85
TLE30.900.86
ATXN7L10.900.85
ADRA2A0.890.92
TBC1D300.890.88
GPRIN10.890.89
SOBP0.890.89
Top 10 negatively co-expressed genes
SERPINB6-0.68-0.76
HEPN1-0.67-0.75
BDH2-0.66-0.80
HSD17B14-0.66-0.78
AIFM3-0.65-0.75
TSC22D4-0.65-0.76
HLA-F-0.64-0.70
S100B-0.64-0.80
CLU-0.64-0.68
AP003117.1-0.63-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006606protein import into nucleusIDA10781616 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA10781616 
GO:0005737cytoplasmIDA10781616 
GO:0016020membraneNAS-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PTTG1EAP1 | HPTTG | MGC126883 | MGC138276 | PTTG | TUTR1pituitary tumor-transforming 1-HPRD,BioGRID10781616 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
UDAYAKUMAR_MED1_TARGETS_DN 240171All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BURTON_ADIPOGENESIS_2 7252All SZGR genes in this pathway
BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN 6045All SZGR genes in this pathway
MARCHINI_TRABECTEDIN_RESISTANCE_DN 4934All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
ELLWOOD_MYC_TARGETS_DN 4027All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP 259159All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.1193919461A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/506193819451A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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