Gene Page: EDC3

Summary
GeneID  80153
Symbol  EDC3
Synonyms  FLJ21128|FLJ31777|LSM16|YJDC|YJEFN2
Description  enhancer of mRNA decapping 3 homolog (S. cerevisiae)
See related  HGNC:26114|MIM:609842|Ensembl:ENSG00000179151|HPRD:07954|
Locus tag  -
Gene type  protein-coding
Map location  15q24.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.815 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRMT2A0.760.76
ZFP410.750.77
MZF10.740.74
RFNG0.730.75
PSMG40.730.70
ARRDC10.720.71
CHKB0.710.68
NARFL0.710.70
ADCK50.710.69
CCDC1300.710.71
Top 10 negatively co-expressed genes
MT-ATP8-0.49-0.51
AF347015.8-0.48-0.45
AF347015.31-0.48-0.45
MT-CYB-0.47-0.45
AF347015.27-0.47-0.45
AF347015.2-0.46-0.43
MT-CO2-0.46-0.43
AF347015.15-0.46-0.43
AF347015.21-0.45-0.48
AL139819.3-0.45-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16364915 |17353931 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
YWHABGW128 | HS1 | KCIP-1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptideAffinity Capture-MSBioGRID17353931 
YWHAG14-3-3GAMMAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptideAffinity Capture-MSBioGRID17353931 
YWHAQ14-3-3 | 1C5 | HS1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptideAffinity Capture-MSBioGRID17353931 
YWHAZKCIP-1 | MGC111427 | MGC126532 | MGC138156tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptideAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_RNA_DEGRADATION 5937All SZGR genes in this pathway
REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE 1510All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY 4829All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN 204114All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN 180116All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.155611Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-22285291m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-29856862m8hsa-miR-29aSZUAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZUAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZUAGCACCAUUUGAAAUCGGU
miR-30-5p2712781A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-3421191251Ahsa-miR-342brainUCUCACACAGAAAUCGCACCCGUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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