Gene Page: SPHKAP
Summary ?
GeneID | 80309 |
Symbol | SPHKAP |
Synonyms | SKIP |
Description | SPHK1 interactor, AKAP domain containing |
Reference | MIM:611646|HGNC:HGNC:30619|Ensembl:ENSG00000153820|HPRD:18052|Vega:OTTHUMG00000153584 |
Gene type | protein-coding |
Map location | 2q36 |
Pascal p-value | 9.312E-5 |
eGene | Cerebellum |
Support | CompositeSet Darnell FMRP targets |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
APPL1 | 0.91 | 0.92 |
KIAA1128 | 0.90 | 0.91 |
NUFIP2 | 0.90 | 0.91 |
CCDC6 | 0.89 | 0.91 |
RAB11FIP2 | 0.89 | 0.90 |
BTRC | 0.89 | 0.90 |
KATNAL1 | 0.89 | 0.92 |
OPA1 | 0.89 | 0.90 |
RABGAP1L | 0.89 | 0.90 |
COL4A3BP | 0.88 | 0.88 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
HIGD1B | -0.57 | -0.62 |
FXYD1 | -0.57 | -0.59 |
C1orf61 | -0.54 | -0.68 |
MT-CO2 | -0.54 | -0.57 |
ENHO | -0.53 | -0.63 |
AF347015.21 | -0.53 | -0.53 |
C1orf54 | -0.53 | -0.62 |
TLCD1 | -0.53 | -0.57 |
AF347015.31 | -0.53 | -0.57 |
PLA2G5 | -0.53 | -0.57 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
BIOCARTA EDG1 PATHWAY | 27 | 24 | All SZGR 2.0 genes in this pathway |
MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
FIRESTEIN PROLIFERATION | 175 | 125 | All SZGR 2.0 genes in this pathway |
MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE VIA TP53 GROUP D | 280 | 158 | All SZGR 2.0 genes in this pathway |