Gene Page: UPK3B
Summary ?
| GeneID | 80761 |
| Symbol | UPK3B |
| Synonyms | P35|UP3B|UPIIIB |
| Description | uroplakin 3B |
| Reference | MIM:611887|HGNC:HGNC:21444|Ensembl:ENSG00000243566|HPRD:15626|Vega:OTTHUMG00000149929 |
| Gene type | protein-coding |
| Map location | 7q11.2 |
| Pascal p-value | 0.403 |
| Fetal beta | -0.314 |
| DMG | 1 (# studies) |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 2 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg22995176 | 7 | 76139470 | UPK3B | 1.95E-5 | -0.459 | 0.016 | DMG:Wockner_2014 |
| cg16393713 | 7 | 76149509 | UPK3B | 4.724E-4 | -0.607 | 0.046 | DMG:Wockner_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10156094 | 7 | 76003967 | UPK3B | ENSG00000243566.2 | 3.808E-7 | 0 | -135778 | gtex_brain_ba24 |
| rs10224066 | 7 | 76004709 | UPK3B | ENSG00000243566.2 | 3.947E-7 | 0 | -135036 | gtex_brain_ba24 |
| rs1806888 | 7 | 76008504 | UPK3B | ENSG00000243566.2 | 5.699E-7 | 0 | -131241 | gtex_brain_ba24 |
| rs4728708 | 7 | 76011592 | UPK3B | ENSG00000243566.2 | 5.855E-7 | 0 | -128153 | gtex_brain_ba24 |
| rs1116209 | 7 | 76012259 | UPK3B | ENSG00000243566.2 | 7.166E-7 | 0 | -127486 | gtex_brain_ba24 |
| rs4728710 | 7 | 76012666 | UPK3B | ENSG00000243566.2 | 6.01E-7 | 0 | -127079 | gtex_brain_ba24 |
| rs11520962 | 7 | 76013265 | UPK3B | ENSG00000243566.2 | 6.509E-7 | 0 | -126480 | gtex_brain_ba24 |
| rs7783542 | 7 | 76014174 | UPK3B | ENSG00000243566.2 | 4.297E-7 | 0 | -125571 | gtex_brain_ba24 |
| rs9692598 | 7 | 76034453 | UPK3B | ENSG00000243566.2 | 5.517E-7 | 0 | -105292 | gtex_brain_ba24 |
| rs6465120 | 7 | 76036364 | UPK3B | ENSG00000243566.2 | 1.514E-6 | 0 | -103381 | gtex_brain_ba24 |
| rs202238946 | 7 | 76042281 | UPK3B | ENSG00000243566.2 | 6.89E-8 | 0 | -97464 | gtex_brain_ba24 |
| rs62476845 | 7 | 76044896 | UPK3B | ENSG00000243566.2 | 6.394E-8 | 0 | -94849 | gtex_brain_ba24 |
| rs62476846 | 7 | 76044969 | UPK3B | ENSG00000243566.2 | 4.074E-9 | 0 | -94776 | gtex_brain_ba24 |
| rs62476847 | 7 | 76045245 | UPK3B | ENSG00000243566.2 | 2.305E-8 | 0 | -94500 | gtex_brain_ba24 |
| rs1019097 | 7 | 76046184 | UPK3B | ENSG00000243566.2 | 3.814E-9 | 0 | -93561 | gtex_brain_ba24 |
| rs1019096 | 7 | 76046324 | UPK3B | ENSG00000243566.2 | 5.079E-10 | 0 | -93421 | gtex_brain_ba24 |
| rs7808402 | 7 | 76047900 | UPK3B | ENSG00000243566.2 | 1.454E-6 | 0 | -91845 | gtex_brain_ba24 |
| rs7790093 | 7 | 76047965 | UPK3B | ENSG00000243566.2 | 1.102E-9 | 0 | -91780 | gtex_brain_ba24 |
| rs199825117 | 7 | 76049016 | UPK3B | ENSG00000243566.2 | 3.591E-9 | 0 | -90729 | gtex_brain_ba24 |
| rs2868366 | 7 | 76050132 | UPK3B | ENSG00000243566.2 | 8.505E-7 | 0 | -89613 | gtex_brain_ba24 |
| rs4728722 | 7 | 76052091 | UPK3B | ENSG00000243566.2 | 1.387E-8 | 0 | -87654 | gtex_brain_ba24 |
| rs35029472 | 7 | 76056562 | UPK3B | ENSG00000243566.2 | 3.052E-9 | 0 | -83183 | gtex_brain_ba24 |
| rs28670022 | 7 | 76057242 | UPK3B | ENSG00000243566.2 | 2.803E-7 | 0 | -82503 | gtex_brain_ba24 |
| rs6465128 | 7 | 76058767 | UPK3B | ENSG00000243566.2 | 2.17E-9 | 0 | -80978 | gtex_brain_ba24 |
| rs887049 | 7 | 76060210 | UPK3B | ENSG00000243566.2 | 2.136E-7 | 0 | -79535 | gtex_brain_ba24 |
| rs887048 | 7 | 76060235 | UPK3B | ENSG00000243566.2 | 2.046E-9 | 0 | -79510 | gtex_brain_ba24 |
| rs3789839 | 7 | 76060533 | UPK3B | ENSG00000243566.2 | 3.272E-7 | 0 | -79212 | gtex_brain_ba24 |
| rs3762030 | 7 | 76062619 | UPK3B | ENSG00000243566.2 | 3.137E-7 | 0 | -77126 | gtex_brain_ba24 |
| rs6966715 | 7 | 76062644 | UPK3B | ENSG00000243566.2 | 3.139E-7 | 0 | -77101 | gtex_brain_ba24 |
| rs3972768 | 7 | 76063333 | UPK3B | ENSG00000243566.2 | 7.877E-7 | 0 | -76412 | gtex_brain_ba24 |
| rs1638132 | 7 | 76069453 | UPK3B | ENSG00000243566.2 | 5.574E-7 | 0 | -70292 | gtex_brain_ba24 |
| rs2906999 | 7 | 76069811 | UPK3B | ENSG00000243566.2 | 7.423E-7 | 0 | -69934 | gtex_brain_ba24 |
| rs147633246 | 7 | 76074342 | UPK3B | ENSG00000243566.2 | 2.058E-7 | 0 | -65403 | gtex_brain_ba24 |
| rs10269955 | 7 | 76075119 | UPK3B | ENSG00000243566.2 | 1.496E-7 | 0 | -64626 | gtex_brain_ba24 |
| rs145455490 | 7 | 76079040 | UPK3B | ENSG00000243566.2 | 4.388E-7 | 0 | -60705 | gtex_brain_ba24 |
| rs28836522 | 7 | 76080479 | UPK3B | ENSG00000243566.2 | 3.858E-7 | 0 | -59266 | gtex_brain_ba24 |
| rs1638083 | 7 | 76103824 | UPK3B | ENSG00000243566.2 | 2.311E-7 | 0 | -35921 | gtex_brain_ba24 |
| rs1799187 | 7 | 76106552 | UPK3B | ENSG00000243566.2 | 1.723E-6 | 0 | -33193 | gtex_brain_ba24 |
| rs1799186 | 7 | 76106561 | UPK3B | ENSG00000243566.2 | 7.299E-7 | 0 | -33184 | gtex_brain_ba24 |
| rs1628255 | 7 | 76110549 | UPK3B | ENSG00000243566.2 | 1.807E-6 | 0 | -29196 | gtex_brain_ba24 |
| rs1628199 | 7 | 76110568 | UPK3B | ENSG00000243566.2 | 6.612E-7 | 0 | -29177 | gtex_brain_ba24 |
| rs1627895 | 7 | 76111296 | UPK3B | ENSG00000243566.2 | 1.029E-7 | 0 | -28449 | gtex_brain_ba24 |
| rs1638074 | 7 | 76112060 | UPK3B | ENSG00000243566.2 | 4.977E-9 | 0 | -27685 | gtex_brain_ba24 |
| rs76926369 | 7 | 76120504 | UPK3B | ENSG00000243566.2 | 1.686E-8 | 0 | -19241 | gtex_brain_ba24 |
| rs1799172 | 7 | 76127071 | UPK3B | ENSG00000243566.2 | 7.172E-10 | 0 | -12674 | gtex_brain_ba24 |
| rs1799127 | 7 | 76127854 | UPK3B | ENSG00000243566.2 | 2.606E-6 | 0 | -11891 | gtex_brain_ba24 |
| rs4728773 | 7 | 76131061 | UPK3B | ENSG00000243566.2 | 2.314E-10 | 0 | -8684 | gtex_brain_ba24 |
| rs4728774 | 7 | 76131169 | UPK3B | ENSG00000243566.2 | 4.856E-10 | 0 | -8576 | gtex_brain_ba24 |
| rs2261368 | 7 | 76131328 | UPK3B | ENSG00000243566.2 | 2.653E-6 | 0 | -8417 | gtex_brain_ba24 |
| rs2690683 | 7 | 76131586 | UPK3B | ENSG00000243566.2 | 1.903E-8 | 0 | -8159 | gtex_brain_ba24 |
| rs6958774 | 7 | 76131650 | UPK3B | ENSG00000243566.2 | 3.65E-8 | 0 | -8095 | gtex_brain_ba24 |
| rs6963784 | 7 | 76131812 | UPK3B | ENSG00000243566.2 | 6.374E-10 | 0 | -7933 | gtex_brain_ba24 |
| rs4236507 | 7 | 76132270 | UPK3B | ENSG00000243566.2 | 2.683E-10 | 0 | -7475 | gtex_brain_ba24 |
| rs4727187 | 7 | 76132473 | UPK3B | ENSG00000243566.2 | 2.688E-10 | 0 | -7272 | gtex_brain_ba24 |
| rs17855260 | 7 | 76132898 | UPK3B | ENSG00000243566.2 | 4.557E-10 | 0 | -6847 | gtex_brain_ba24 |
| rs201090408 | 7 | 76133427 | UPK3B | ENSG00000243566.2 | 3.804E-9 | 0 | -6318 | gtex_brain_ba24 |
| rs11980492 | 7 | 76134236 | UPK3B | ENSG00000243566.2 | 2.058E-10 | 0 | -5509 | gtex_brain_ba24 |
| rs7807719 | 7 | 76134433 | UPK3B | ENSG00000243566.2 | 2.061E-10 | 0 | -5312 | gtex_brain_ba24 |
| rs7398 | 7 | 76135134 | UPK3B | ENSG00000243566.2 | 6.211E-10 | 0 | -4611 | gtex_brain_ba24 |
| rs4728783 | 7 | 76135677 | UPK3B | ENSG00000243566.2 | 2.99E-10 | 0 | -4068 | gtex_brain_ba24 |
| rs4728784 | 7 | 76135821 | UPK3B | ENSG00000243566.2 | 3.636E-10 | 0 | -3924 | gtex_brain_ba24 |
| rs4728785 | 7 | 76135921 | UPK3B | ENSG00000243566.2 | 4.19E-10 | 0 | -3824 | gtex_brain_ba24 |
| rs4728786 | 7 | 76135948 | UPK3B | ENSG00000243566.2 | 4.363E-10 | 0 | -3797 | gtex_brain_ba24 |
| rs4728788 | 7 | 76136719 | UPK3B | ENSG00000243566.2 | 1.072E-9 | 0 | -3026 | gtex_brain_ba24 |
| rs2110464 | 7 | 76137375 | UPK3B | ENSG00000243566.2 | 2.651E-9 | 0 | -2370 | gtex_brain_ba24 |
| rs34656908 | 7 | 76137924 | UPK3B | ENSG00000243566.2 | 2.496E-9 | 0 | -1821 | gtex_brain_ba24 |
| rs112158882 | 7 | 76138796 | UPK3B | ENSG00000243566.2 | 2.524E-9 | 0 | -949 | gtex_brain_ba24 |
| rs1861105 | 7 | 76138835 | UPK3B | ENSG00000243566.2 | 1.007E-7 | 0 | -910 | gtex_brain_ba24 |
| rs1861104 | 7 | 76138845 | UPK3B | ENSG00000243566.2 | 1.198E-7 | 0 | -900 | gtex_brain_ba24 |
| rs1808308 | 7 | 76138967 | UPK3B | ENSG00000243566.2 | 2.537E-9 | 0 | -778 | gtex_brain_ba24 |
| rs1808307 | 7 | 76139115 | UPK3B | ENSG00000243566.2 | 2.563E-9 | 0 | -630 | gtex_brain_ba24 |
| rs4727191 | 7 | 76139384 | UPK3B | ENSG00000243566.2 | 2.567E-9 | 0 | -361 | gtex_brain_ba24 |
| rs10952935 | 7 | 76139395 | UPK3B | ENSG00000243566.2 | 2.562E-9 | 0 | -350 | gtex_brain_ba24 |
| rs10952936 | 7 | 76139453 | UPK3B | ENSG00000243566.2 | 2.58E-9 | 0 | -292 | gtex_brain_ba24 |
| rs2286988 | 7 | 76142536 | UPK3B | ENSG00000243566.2 | 3.255E-9 | 0 | 2791 | gtex_brain_ba24 |
| rs2286989 | 7 | 76142872 | UPK3B | ENSG00000243566.2 | 3.228E-9 | 0 | 3127 | gtex_brain_ba24 |
| rs2286990 | 7 | 76142930 | UPK3B | ENSG00000243566.2 | 3.227E-9 | 0 | 3185 | gtex_brain_ba24 |
| rs887911 | 7 | 76143705 | UPK3B | ENSG00000243566.2 | 3.301E-9 | 0 | 3960 | gtex_brain_ba24 |
| rs2528284 | 7 | 76144156 | UPK3B | ENSG00000243566.2 | 3.331E-9 | 0 | 4411 | gtex_brain_ba24 |
| rs1636632 | 7 | 76144483 | UPK3B | ENSG00000243566.2 | 3.349E-9 | 0 | 4738 | gtex_brain_ba24 |
| rs3901999 | 7 | 76170705 | UPK3B | ENSG00000243566.2 | 8.998E-7 | 0 | 30960 | gtex_brain_ba24 |
| rs2528203 | 7 | 76173528 | UPK3B | ENSG00000243566.2 | 8.266E-9 | 0 | 33783 | gtex_brain_ba24 |
| rs2528204 | 7 | 76173536 | UPK3B | ENSG00000243566.2 | 1.759E-8 | 0 | 33791 | gtex_brain_ba24 |
| rs2949288 | 7 | 76175264 | UPK3B | ENSG00000243566.2 | 1.306E-7 | 0 | 35519 | gtex_brain_ba24 |
| rs201710700 | 7 | 76175351 | UPK3B | ENSG00000243566.2 | 1.007E-7 | 0 | 35606 | gtex_brain_ba24 |
| rs2533952 | 7 | 76198932 | UPK3B | ENSG00000243566.2 | 1.012E-6 | 0 | 59187 | gtex_brain_ba24 |
| rs804025 | 7 | 76200250 | UPK3B | ENSG00000243566.2 | 1.18E-6 | 0 | 60505 | gtex_brain_ba24 |
| rs1625567 | 7 | 76205396 | UPK3B | ENSG00000243566.2 | 1.541E-6 | 0 | 65651 | gtex_brain_ba24 |
| rs1799135 | 7 | 76210741 | UPK3B | ENSG00000243566.2 | 1.097E-6 | 0 | 70996 | gtex_brain_ba24 |
| rs1799139 | 7 | 76219946 | UPK3B | ENSG00000243566.2 | 8.472E-7 | 0 | 80201 | gtex_brain_ba24 |
| rs1754178 | 7 | 76226411 | UPK3B | ENSG00000243566.2 | 9.782E-7 | 0 | 86666 | gtex_brain_ba24 |
| rs1799140 | 7 | 76227250 | UPK3B | ENSG00000243566.2 | 9.242E-7 | 0 | 87505 | gtex_brain_ba24 |
| rs804002 | 7 | 76228642 | UPK3B | ENSG00000243566.2 | 9.62E-7 | 0 | 88897 | gtex_brain_ba24 |
| rs1754182 | 7 | 76229947 | UPK3B | ENSG00000243566.2 | 1.02E-6 | 0 | 90202 | gtex_brain_ba24 |
| rs1799211 | 7 | 76240677 | UPK3B | ENSG00000243566.2 | 2.147E-6 | 0 | 100932 | gtex_brain_ba24 |
| rs77156628 | 7 | 76251842 | UPK3B | ENSG00000243566.2 | 7.287E-7 | 0 | 112097 | gtex_brain_ba24 |
| rs2480243 | 7 | 76254672 | UPK3B | ENSG00000243566.2 | 1.744E-6 | 0 | 114927 | gtex_brain_ba24 |
| rs73365257 | 7 | 76266035 | UPK3B | ENSG00000243566.2 | 1.371E-6 | 0 | 126290 | gtex_brain_ba24 |
| rs10156094 | 7 | 76003967 | UPK3B | ENSG00000243566.2 | 8.404E-9 | 0 | -135778 | gtex_brain_putamen_basal |
| rs10224066 | 7 | 76004709 | UPK3B | ENSG00000243566.2 | 7.059E-9 | 0 | -135036 | gtex_brain_putamen_basal |
| rs1806888 | 7 | 76008504 | UPK3B | ENSG00000243566.2 | 3.085E-9 | 0 | -131241 | gtex_brain_putamen_basal |
| rs4728708 | 7 | 76011592 | UPK3B | ENSG00000243566.2 | 2.589E-9 | 0 | -128153 | gtex_brain_putamen_basal |
| rs1116209 | 7 | 76012259 | UPK3B | ENSG00000243566.2 | 1.561E-9 | 0 | -127486 | gtex_brain_putamen_basal |
| rs4728710 | 7 | 76012666 | UPK3B | ENSG00000243566.2 | 2.333E-9 | 0 | -127079 | gtex_brain_putamen_basal |
| rs11520962 | 7 | 76013265 | UPK3B | ENSG00000243566.2 | 1.55E-9 | 0 | -126480 | gtex_brain_putamen_basal |
| rs7792882 | 7 | 76013715 | UPK3B | ENSG00000243566.2 | 7.447E-9 | 0 | -126030 | gtex_brain_putamen_basal |
| rs7783542 | 7 | 76014174 | UPK3B | ENSG00000243566.2 | 1.392E-9 | 0 | -125571 | gtex_brain_putamen_basal |
| rs10227908 | 7 | 76014224 | UPK3B | ENSG00000243566.2 | 5.607E-9 | 0 | -125521 | gtex_brain_putamen_basal |
| rs11771651 | 7 | 76016222 | UPK3B | ENSG00000243566.2 | 2.062E-9 | 0 | -123523 | gtex_brain_putamen_basal |
| rs2868367 | 7 | 76016648 | UPK3B | ENSG00000243566.2 | 1.625E-9 | 0 | -123097 | gtex_brain_putamen_basal |
| rs4415243 | 7 | 76016979 | UPK3B | ENSG00000243566.2 | 3.588E-9 | 0 | -122766 | gtex_brain_putamen_basal |
| rs10281089 | 7 | 76017997 | UPK3B | ENSG00000243566.2 | 7.99E-9 | 0 | -121748 | gtex_brain_putamen_basal |
| rs1966269 | 7 | 76020550 | UPK3B | ENSG00000243566.2 | 8.105E-10 | 0 | -119195 | gtex_brain_putamen_basal |
| rs2903811 | 7 | 76021760 | UPK3B | ENSG00000243566.2 | 1.93E-9 | 0 | -117985 | gtex_brain_putamen_basal |
| rs4617087 | 7 | 76022497 | UPK3B | ENSG00000243566.2 | 1.927E-9 | 0 | -117248 | gtex_brain_putamen_basal |
| rs10261314 | 7 | 76023029 | UPK3B | ENSG00000243566.2 | 8.224E-10 | 0 | -116716 | gtex_brain_putamen_basal |
| rs6963070 | 7 | 76027235 | UPK3B | ENSG00000243566.2 | 2.975E-10 | 0 | -112510 | gtex_brain_putamen_basal |
| rs11975972 | 7 | 76028869 | UPK3B | ENSG00000243566.2 | 7.367E-10 | 0 | -110876 | gtex_brain_putamen_basal |
| rs6961135 | 7 | 76031349 | UPK3B | ENSG00000243566.2 | 6.245E-10 | 0 | -108396 | gtex_brain_putamen_basal |
| rs10228441 | 7 | 76032291 | UPK3B | ENSG00000243566.2 | 5.889E-10 | 0 | -107454 | gtex_brain_putamen_basal |
| rs11760779 | 7 | 76033906 | UPK3B | ENSG00000243566.2 | 1.696E-9 | 0 | -105839 | gtex_brain_putamen_basal |
| rs11760803 | 7 | 76033956 | UPK3B | ENSG00000243566.2 | 8.775E-10 | 0 | -105789 | gtex_brain_putamen_basal |
| rs55722505 | 7 | 76034150 | UPK3B | ENSG00000243566.2 | 3.525E-8 | 0 | -105595 | gtex_brain_putamen_basal |
| rs55646977 | 7 | 76034216 | UPK3B | ENSG00000243566.2 | 1.682E-9 | 0 | -105529 | gtex_brain_putamen_basal |
| rs9692598 | 7 | 76034453 | UPK3B | ENSG00000243566.2 | 2.125E-8 | 0 | -105292 | gtex_brain_putamen_basal |
| rs1968108 | 7 | 76034794 | UPK3B | ENSG00000243566.2 | 8.36E-10 | 0 | -104951 | gtex_brain_putamen_basal |
| rs1968107 | 7 | 76035372 | UPK3B | ENSG00000243566.2 | 7.518E-10 | 0 | -104373 | gtex_brain_putamen_basal |
| rs28450657 | 7 | 76035520 | UPK3B | ENSG00000243566.2 | 2.924E-7 | 0 | -104225 | gtex_brain_putamen_basal |
| rs1476756 | 7 | 76035847 | UPK3B | ENSG00000243566.2 | 1.34E-9 | 0 | -103898 | gtex_brain_putamen_basal |
| rs6944415 | 7 | 76035947 | UPK3B | ENSG00000243566.2 | 7.245E-10 | 0 | -103798 | gtex_brain_putamen_basal |
| rs6958115 | 7 | 76036166 | UPK3B | ENSG00000243566.2 | 2.506E-9 | 0 | -103579 | gtex_brain_putamen_basal |
| rs6465120 | 7 | 76036364 | UPK3B | ENSG00000243566.2 | 2.606E-9 | 0 | -103381 | gtex_brain_putamen_basal |
| rs6465121 | 7 | 76036380 | UPK3B | ENSG00000243566.2 | 9.577E-10 | 0 | -103365 | gtex_brain_putamen_basal |
| rs6958621 | 7 | 76036493 | UPK3B | ENSG00000243566.2 | 2.766E-9 | 0 | -103252 | gtex_brain_putamen_basal |
| rs11489557 | 7 | 76036569 | UPK3B | ENSG00000243566.2 | 2.84E-9 | 0 | -103176 | gtex_brain_putamen_basal |
| rs62476836 | 7 | 76036751 | UPK3B | ENSG00000243566.2 | 4.035E-8 | 0 | -102994 | gtex_brain_putamen_basal |
| rs55650029 | 7 | 76037122 | UPK3B | ENSG00000243566.2 | 1.308E-9 | 0 | -102623 | gtex_brain_putamen_basal |
| rs57966166 | 7 | 76037190 | UPK3B | ENSG00000243566.2 | 3.533E-9 | 0 | -102555 | gtex_brain_putamen_basal |
| rs11486951 | 7 | 76038153 | UPK3B | ENSG00000243566.2 | 3.356E-9 | 0 | -101592 | gtex_brain_putamen_basal |
| rs10235405 | 7 | 76039182 | UPK3B | ENSG00000243566.2 | 1.778E-9 | 0 | -100563 | gtex_brain_putamen_basal |
| rs2017544 | 7 | 76039448 | UPK3B | ENSG00000243566.2 | 4.234E-10 | 0 | -100297 | gtex_brain_putamen_basal |
| rs202238946 | 7 | 76042281 | UPK3B | ENSG00000243566.2 | 4.504E-9 | 0 | -97464 | gtex_brain_putamen_basal |
| rs112904325 | 7 | 76042282 | UPK3B | ENSG00000243566.2 | 9.845E-8 | 0 | -97463 | gtex_brain_putamen_basal |
| rs62476846 | 7 | 76044969 | UPK3B | ENSG00000243566.2 | 1.259E-8 | 0 | -94776 | gtex_brain_putamen_basal |
| rs62476847 | 7 | 76045245 | UPK3B | ENSG00000243566.2 | 6.684E-8 | 0 | -94500 | gtex_brain_putamen_basal |
| rs1019097 | 7 | 76046184 | UPK3B | ENSG00000243566.2 | 1.162E-8 | 0 | -93561 | gtex_brain_putamen_basal |
| rs1019096 | 7 | 76046324 | UPK3B | ENSG00000243566.2 | 1.054E-8 | 0 | -93421 | gtex_brain_putamen_basal |
| rs7808402 | 7 | 76047900 | UPK3B | ENSG00000243566.2 | 9.963E-8 | 0 | -91845 | gtex_brain_putamen_basal |
| rs7790093 | 7 | 76047965 | UPK3B | ENSG00000243566.2 | 1.463E-7 | 0 | -91780 | gtex_brain_putamen_basal |
| rs199825117 | 7 | 76049016 | UPK3B | ENSG00000243566.2 | 6.105E-11 | 0 | -90729 | gtex_brain_putamen_basal |
| rs2868366 | 7 | 76050132 | UPK3B | ENSG00000243566.2 | 1.334E-11 | 0 | -89613 | gtex_brain_putamen_basal |
| rs28632114 | 7 | 76051951 | UPK3B | ENSG00000243566.2 | 1.461E-6 | 0 | -87794 | gtex_brain_putamen_basal |
| rs4728722 | 7 | 76052091 | UPK3B | ENSG00000243566.2 | 9.915E-11 | 0 | -87654 | gtex_brain_putamen_basal |
| rs28609359 | 7 | 76055593 | UPK3B | ENSG00000243566.2 | 6.987E-9 | 0 | -84152 | gtex_brain_putamen_basal |
| rs35029472 | 7 | 76056562 | UPK3B | ENSG00000243566.2 | 9.648E-13 | 0 | -83183 | gtex_brain_putamen_basal |
| rs28670022 | 7 | 76057242 | UPK3B | ENSG00000243566.2 | 1.729E-10 | 0 | -82503 | gtex_brain_putamen_basal |
| rs6465128 | 7 | 76058767 | UPK3B | ENSG00000243566.2 | 1.231E-12 | 0 | -80978 | gtex_brain_putamen_basal |
| rs3789833 | 7 | 76059561 | UPK3B | ENSG00000243566.2 | 1.219E-6 | 0 | -80184 | gtex_brain_putamen_basal |
| rs3789834 | 7 | 76059838 | UPK3B | ENSG00000243566.2 | 1.217E-6 | 0 | -79907 | gtex_brain_putamen_basal |
| rs887049 | 7 | 76060210 | UPK3B | ENSG00000243566.2 | 3.068E-12 | 0 | -79535 | gtex_brain_putamen_basal |
| rs887048 | 7 | 76060235 | UPK3B | ENSG00000243566.2 | 1.808E-12 | 0 | -79510 | gtex_brain_putamen_basal |
| rs3789839 | 7 | 76060533 | UPK3B | ENSG00000243566.2 | 4.532E-10 | 0 | -79212 | gtex_brain_putamen_basal |
| rs77214139 | 7 | 76061348 | UPK3B | ENSG00000243566.2 | 1.192E-6 | 0 | -78397 | gtex_brain_putamen_basal |
| rs4509249 | 7 | 76061776 | UPK3B | ENSG00000243566.2 | 8.662E-7 | 0 | -77969 | gtex_brain_putamen_basal |
| rs3762030 | 7 | 76062619 | UPK3B | ENSG00000243566.2 | 3.295E-12 | 0 | -77126 | gtex_brain_putamen_basal |
| rs28427180 | 7 | 76062623 | UPK3B | ENSG00000243566.2 | 1.247E-6 | 0 | -77122 | gtex_brain_putamen_basal |
| rs6966715 | 7 | 76062644 | UPK3B | ENSG00000243566.2 | 9.463E-12 | 0 | -77101 | gtex_brain_putamen_basal |
| rs3972768 | 7 | 76063333 | UPK3B | ENSG00000243566.2 | 3.733E-8 | 0 | -76412 | gtex_brain_putamen_basal |
| rs62479062 | 7 | 76065124 | UPK3B | ENSG00000243566.2 | 1.039E-6 | 0 | -74621 | gtex_brain_putamen_basal |
| rs1541454 | 7 | 76066266 | UPK3B | ENSG00000243566.2 | 6.56E-10 | 0 | -73479 | gtex_brain_putamen_basal |
| rs1799222 | 7 | 76066269 | UPK3B | ENSG00000243566.2 | 2.086E-8 | 0 | -73476 | gtex_brain_putamen_basal |
| rs62475568 | 7 | 76069358 | UPK3B | ENSG00000243566.2 | 3.681E-7 | 0 | -70387 | gtex_brain_putamen_basal |
| rs1638132 | 7 | 76069453 | UPK3B | ENSG00000243566.2 | 2.501E-11 | 0 | -70292 | gtex_brain_putamen_basal |
| rs2906999 | 7 | 76069811 | UPK3B | ENSG00000243566.2 | 7.286E-10 | 0 | -69934 | gtex_brain_putamen_basal |
| rs200426507 | 7 | 76071412 | UPK3B | ENSG00000243566.2 | 6.854E-7 | 0 | -68333 | gtex_brain_putamen_basal |
| rs147633246 | 7 | 76074342 | UPK3B | ENSG00000243566.2 | 1.255E-7 | 0 | -65403 | gtex_brain_putamen_basal |
| rs10269955 | 7 | 76075119 | UPK3B | ENSG00000243566.2 | 2.306E-10 | 0 | -64626 | gtex_brain_putamen_basal |
| rs145455490 | 7 | 76079040 | UPK3B | ENSG00000243566.2 | 1.313E-8 | 0 | -60705 | gtex_brain_putamen_basal |
| rs28836522 | 7 | 76080479 | UPK3B | ENSG00000243566.2 | 4.318E-12 | 0 | -59266 | gtex_brain_putamen_basal |
| rs2430286 | 7 | 76081359 | UPK3B | ENSG00000243566.2 | 3.433E-11 | 0 | -58386 | gtex_brain_putamen_basal |
| rs113841149 | 7 | 76081509 | UPK3B | ENSG00000243566.2 | 3.765E-8 | 0 | -58236 | gtex_brain_putamen_basal |
| rs80058120 | 7 | 76084361 | UPK3B | ENSG00000243566.2 | 2.175E-7 | 0 | -55384 | gtex_brain_putamen_basal |
| rs143691932 | 7 | 76085166 | UPK3B | ENSG00000243566.2 | 3.617E-9 | 0 | -54579 | gtex_brain_putamen_basal |
| rs28437796 | 7 | 76089647 | UPK3B | ENSG00000243566.2 | 8.315E-7 | 0 | -50098 | gtex_brain_putamen_basal |
| rs1799200 | 7 | 76094015 | UPK3B | ENSG00000243566.2 | 2.217E-10 | 0 | -45730 | gtex_brain_putamen_basal |
| rs1616563 | 7 | 76098742 | UPK3B | ENSG00000243566.2 | 6.494E-8 | 0 | -41003 | gtex_brain_putamen_basal |
| rs1638083 | 7 | 76103824 | UPK3B | ENSG00000243566.2 | 1.069E-10 | 0 | -35921 | gtex_brain_putamen_basal |
| rs1638081 | 7 | 76106188 | UPK3B | ENSG00000243566.2 | 5.031E-7 | 0 | -33557 | gtex_brain_putamen_basal |
| rs28449857 | 7 | 76106474 | UPK3B | ENSG00000243566.2 | 1.812E-7 | 0 | -33271 | gtex_brain_putamen_basal |
| rs200752892 | 7 | 76106474 | UPK3B | ENSG00000243566.2 | 1.582E-7 | 0 | -33271 | gtex_brain_putamen_basal |
| rs1799187 | 7 | 76106552 | UPK3B | ENSG00000243566.2 | 2.413E-10 | 0 | -33193 | gtex_brain_putamen_basal |
| rs1799186 | 7 | 76106561 | UPK3B | ENSG00000243566.2 | 7.747E-9 | 0 | -33184 | gtex_brain_putamen_basal |
| rs62475650 | 7 | 76106983 | UPK3B | ENSG00000243566.2 | 8.428E-10 | 0 | -32762 | gtex_brain_putamen_basal |
| rs1628255 | 7 | 76110549 | UPK3B | ENSG00000243566.2 | 3.148E-10 | 0 | -29196 | gtex_brain_putamen_basal |
| rs1628199 | 7 | 76110568 | UPK3B | ENSG00000243566.2 | 5.275E-11 | 0 | -29177 | gtex_brain_putamen_basal |
| rs1627895 | 7 | 76111296 | UPK3B | ENSG00000243566.2 | 2.897E-12 | 0 | -28449 | gtex_brain_putamen_basal |
| rs140471903 | 7 | 76111532 | UPK3B | ENSG00000243566.2 | 3.787E-7 | 0 | -28213 | gtex_brain_putamen_basal |
| rs4236506 | 7 | 76111835 | UPK3B | ENSG00000243566.2 | 2.228E-6 | 0 | -27910 | gtex_brain_putamen_basal |
| rs1638074 | 7 | 76112060 | UPK3B | ENSG00000243566.2 | 2.706E-12 | 0 | -27685 | gtex_brain_putamen_basal |
| rs116848658 | 7 | 76112955 | UPK3B | ENSG00000243566.2 | 2.444E-8 | 0 | -26790 | gtex_brain_putamen_basal |
| rs76926369 | 7 | 76120504 | UPK3B | ENSG00000243566.2 | 6.753E-8 | 0 | -19241 | gtex_brain_putamen_basal |
| rs1799172 | 7 | 76127071 | UPK3B | ENSG00000243566.2 | 2.672E-9 | 0 | -12674 | gtex_brain_putamen_basal |
| rs1799127 | 7 | 76127854 | UPK3B | ENSG00000243566.2 | 3.21E-8 | 0 | -11891 | gtex_brain_putamen_basal |
| rs2280611 | 7 | 76130978 | UPK3B | ENSG00000243566.2 | 5.068E-9 | 0 | -8767 | gtex_brain_putamen_basal |
| rs4728773 | 7 | 76131061 | UPK3B | ENSG00000243566.2 | 1.332E-12 | 0 | -8684 | gtex_brain_putamen_basal |
| rs4728774 | 7 | 76131169 | UPK3B | ENSG00000243566.2 | 7.509E-12 | 0 | -8576 | gtex_brain_putamen_basal |
| rs2690683 | 7 | 76131586 | UPK3B | ENSG00000243566.2 | 2.55E-9 | 0 | -8159 | gtex_brain_putamen_basal |
| rs6958774 | 7 | 76131650 | UPK3B | ENSG00000243566.2 | 5.433E-11 | 0 | -8095 | gtex_brain_putamen_basal |
| rs6963784 | 7 | 76131812 | UPK3B | ENSG00000243566.2 | 1.017E-12 | 0 | -7933 | gtex_brain_putamen_basal |
| rs4236507 | 7 | 76132270 | UPK3B | ENSG00000243566.2 | 1.26E-12 | 0 | -7475 | gtex_brain_putamen_basal |
| rs4727187 | 7 | 76132473 | UPK3B | ENSG00000243566.2 | 1.253E-12 | 0 | -7272 | gtex_brain_putamen_basal |
| rs17855260 | 7 | 76132898 | UPK3B | ENSG00000243566.2 | 5.626E-10 | 0 | -6847 | gtex_brain_putamen_basal |
| rs201090408 | 7 | 76133427 | UPK3B | ENSG00000243566.2 | 2.821E-9 | 0 | -6318 | gtex_brain_putamen_basal |
| rs1465314 | 7 | 76134203 | UPK3B | ENSG00000243566.2 | 1.578E-6 | 0 | -5542 | gtex_brain_putamen_basal |
| rs11980492 | 7 | 76134236 | UPK3B | ENSG00000243566.2 | 1.242E-13 | 0 | -5509 | gtex_brain_putamen_basal |
| rs7807719 | 7 | 76134433 | UPK3B | ENSG00000243566.2 | 1.242E-13 | 0 | -5312 | gtex_brain_putamen_basal |
| rs7398 | 7 | 76135134 | UPK3B | ENSG00000243566.2 | 1.502E-12 | 0 | -4611 | gtex_brain_putamen_basal |
| rs4728783 | 7 | 76135677 | UPK3B | ENSG00000243566.2 | 1.258E-13 | 0 | -4068 | gtex_brain_putamen_basal |
| rs4728784 | 7 | 76135821 | UPK3B | ENSG00000243566.2 | 1.26E-13 | 0 | -3924 | gtex_brain_putamen_basal |
| rs4728785 | 7 | 76135921 | UPK3B | ENSG00000243566.2 | 1.26E-13 | 0 | -3824 | gtex_brain_putamen_basal |
| rs4728786 | 7 | 76135948 | UPK3B | ENSG00000243566.2 | 1.26E-13 | 0 | -3797 | gtex_brain_putamen_basal |
| rs4728788 | 7 | 76136719 | UPK3B | ENSG00000243566.2 | 1.145E-13 | 0 | -3026 | gtex_brain_putamen_basal |
| rs2110464 | 7 | 76137375 | UPK3B | ENSG00000243566.2 | 1.059E-13 | 0 | -2370 | gtex_brain_putamen_basal |
| rs34656908 | 7 | 76137924 | UPK3B | ENSG00000243566.2 | 1.306E-13 | 0 | -1821 | gtex_brain_putamen_basal |
| rs112158882 | 7 | 76138796 | UPK3B | ENSG00000243566.2 | 1.301E-13 | 0 | -949 | gtex_brain_putamen_basal |
| rs1861105 | 7 | 76138835 | UPK3B | ENSG00000243566.2 | 1.327E-13 | 0 | -910 | gtex_brain_putamen_basal |
| rs1861104 | 7 | 76138845 | UPK3B | ENSG00000243566.2 | 5.496E-13 | 0 | -900 | gtex_brain_putamen_basal |
| rs1808308 | 7 | 76138967 | UPK3B | ENSG00000243566.2 | 1.297E-13 | 0 | -778 | gtex_brain_putamen_basal |
| rs1808307 | 7 | 76139115 | UPK3B | ENSG00000243566.2 | 2.167E-13 | 0 | -630 | gtex_brain_putamen_basal |
| rs4727191 | 7 | 76139384 | UPK3B | ENSG00000243566.2 | 1.305E-13 | 0 | -361 | gtex_brain_putamen_basal |
| rs10952935 | 7 | 76139395 | UPK3B | ENSG00000243566.2 | 1.303E-13 | 0 | -350 | gtex_brain_putamen_basal |
| rs10952936 | 7 | 76139453 | UPK3B | ENSG00000243566.2 | 1.309E-13 | 0 | -292 | gtex_brain_putamen_basal |
| rs62476499 | 7 | 76140451 | UPK3B | ENSG00000243566.2 | 2.094E-6 | 0 | 706 | gtex_brain_putamen_basal |
| rs2286988 | 7 | 76142536 | UPK3B | ENSG00000243566.2 | 1.102E-11 | 0 | 2791 | gtex_brain_putamen_basal |
| rs2286989 | 7 | 76142872 | UPK3B | ENSG00000243566.2 | 1.385E-13 | 0 | 3127 | gtex_brain_putamen_basal |
| rs2286990 | 7 | 76142930 | UPK3B | ENSG00000243566.2 | 1.384E-13 | 0 | 3185 | gtex_brain_putamen_basal |
| rs887911 | 7 | 76143705 | UPK3B | ENSG00000243566.2 | 1.386E-13 | 0 | 3960 | gtex_brain_putamen_basal |
| rs2528284 | 7 | 76144156 | UPK3B | ENSG00000243566.2 | 1.389E-13 | 0 | 4411 | gtex_brain_putamen_basal |
| rs1636632 | 7 | 76144483 | UPK3B | ENSG00000243566.2 | 1.39E-13 | 0 | 4738 | gtex_brain_putamen_basal |
| rs782487 | 7 | 76161400 | UPK3B | ENSG00000243566.2 | 7.015E-9 | 0 | 21655 | gtex_brain_putamen_basal |
| rs3901999 | 7 | 76170705 | UPK3B | ENSG00000243566.2 | 1.418E-6 | 0 | 30960 | gtex_brain_putamen_basal |
| rs2528203 | 7 | 76173528 | UPK3B | ENSG00000243566.2 | 2.282E-8 | 0 | 33783 | gtex_brain_putamen_basal |
| rs2528204 | 7 | 76173536 | UPK3B | ENSG00000243566.2 | 2.304E-8 | 0 | 33791 | gtex_brain_putamen_basal |
| rs2949288 | 7 | 76175264 | UPK3B | ENSG00000243566.2 | 1.051E-10 | 0 | 35519 | gtex_brain_putamen_basal |
| rs201710700 | 7 | 76175351 | UPK3B | ENSG00000243566.2 | 1.058E-8 | 0 | 35606 | gtex_brain_putamen_basal |
| rs1799131 | 7 | 76178113 | UPK3B | ENSG00000243566.2 | 4.18E-11 | 0 | 38368 | gtex_brain_putamen_basal |
| rs544543694 | 7 | 76181713 | UPK3B | ENSG00000243566.2 | 3.754E-8 | 0 | 41968 | gtex_brain_putamen_basal |
| rs810699 | 7 | 76182731 | UPK3B | ENSG00000243566.2 | 3.121E-10 | 0 | 42986 | gtex_brain_putamen_basal |
| rs74695153 | 7 | 76184983 | UPK3B | ENSG00000243566.2 | 7.402E-7 | 0 | 45238 | gtex_brain_putamen_basal |
| rs10239706 | 7 | 76185877 | UPK3B | ENSG00000243566.2 | 1.257E-6 | 0 | 46132 | gtex_brain_putamen_basal |
| rs62477976 | 7 | 76188633 | UPK3B | ENSG00000243566.2 | 7.486E-8 | 0 | 48888 | gtex_brain_putamen_basal |
| rs71521133 | 7 | 76190268 | UPK3B | ENSG00000243566.2 | 2.514E-9 | 0 | 50523 | gtex_brain_putamen_basal |
| rs10250158 | 7 | 76190762 | UPK3B | ENSG00000243566.2 | 6.781E-8 | 0 | 51017 | gtex_brain_putamen_basal |
| rs62477978 | 7 | 76191766 | UPK3B | ENSG00000243566.2 | 1.506E-6 | 0 | 52021 | gtex_brain_putamen_basal |
| rs140081370 | 7 | 76193193 | UPK3B | ENSG00000243566.2 | 7.475E-8 | 0 | 53448 | gtex_brain_putamen_basal |
| rs62477980 | 7 | 76194028 | UPK3B | ENSG00000243566.2 | 2.193E-8 | 0 | 54283 | gtex_brain_putamen_basal |
| rs143107992 | 7 | 76195805 | UPK3B | ENSG00000243566.2 | 5.148E-7 | 0 | 56060 | gtex_brain_putamen_basal |
| rs10231460 | 7 | 76196425 | UPK3B | ENSG00000243566.2 | 6.461E-7 | 0 | 56680 | gtex_brain_putamen_basal |
| rs2771164 | 7 | 76197643 | UPK3B | ENSG00000243566.2 | 2.18E-11 | 0 | 57898 | gtex_brain_putamen_basal |
| rs2533952 | 7 | 76198932 | UPK3B | ENSG00000243566.2 | 1.346E-10 | 0 | 59187 | gtex_brain_putamen_basal |
| rs804025 | 7 | 76200250 | UPK3B | ENSG00000243566.2 | 1.246E-11 | 0 | 60505 | gtex_brain_putamen_basal |
| rs62477985 | 7 | 76203889 | UPK3B | ENSG00000243566.2 | 1.472E-6 | 0 | 64144 | gtex_brain_putamen_basal |
| rs1625567 | 7 | 76205396 | UPK3B | ENSG00000243566.2 | 3.059E-11 | 0 | 65651 | gtex_brain_putamen_basal |
| rs3851929 | 7 | 76207290 | UPK3B | ENSG00000243566.2 | 1.274E-7 | 0 | 67545 | gtex_brain_putamen_basal |
| rs1799135 | 7 | 76210741 | UPK3B | ENSG00000243566.2 | 2.167E-11 | 0 | 70996 | gtex_brain_putamen_basal |
| rs77896824 | 7 | 76213662 | UPK3B | ENSG00000243566.2 | 1.861E-6 | 0 | 73917 | gtex_brain_putamen_basal |
| rs10247542 | 7 | 76215092 | UPK3B | ENSG00000243566.2 | 1.202E-6 | 0 | 75347 | gtex_brain_putamen_basal |
| rs1754174 | 7 | 76215602 | UPK3B | ENSG00000243566.2 | 7.499E-9 | 0 | 75857 | gtex_brain_putamen_basal |
| rs11505779 | 7 | 76216384 | UPK3B | ENSG00000243566.2 | 2.003E-6 | 0 | 76639 | gtex_brain_putamen_basal |
| rs11505688 | 7 | 76216621 | UPK3B | ENSG00000243566.2 | 1.943E-6 | 0 | 76876 | gtex_brain_putamen_basal |
| rs201911157 | 7 | 76216728 | UPK3B | ENSG00000243566.2 | 2.021E-6 | 0 | 76983 | gtex_brain_putamen_basal |
| rs1799139 | 7 | 76219946 | UPK3B | ENSG00000243566.2 | 1.941E-11 | 0 | 80201 | gtex_brain_putamen_basal |
| rs10264853 | 7 | 76222181 | UPK3B | ENSG00000243566.2 | 1.259E-6 | 0 | 82436 | gtex_brain_putamen_basal |
| rs10268836 | 7 | 76222939 | UPK3B | ENSG00000243566.2 | 2.084E-6 | 0 | 83194 | gtex_brain_putamen_basal |
| rs1754178 | 7 | 76226411 | UPK3B | ENSG00000243566.2 | 6.753E-10 | 0 | 86666 | gtex_brain_putamen_basal |
| rs1799140 | 7 | 76227250 | UPK3B | ENSG00000243566.2 | 6.713E-10 | 0 | 87505 | gtex_brain_putamen_basal |
| rs804002 | 7 | 76228642 | UPK3B | ENSG00000243566.2 | 7.011E-10 | 0 | 88897 | gtex_brain_putamen_basal |
| rs1754180 | 7 | 76228679 | UPK3B | ENSG00000243566.2 | 3.822E-9 | 0 | 88934 | gtex_brain_putamen_basal |
| rs1799142 | 7 | 76228705 | UPK3B | ENSG00000243566.2 | 6.984E-7 | 0 | 88960 | gtex_brain_putamen_basal |
| rs10258554 | 7 | 76229141 | UPK3B | ENSG00000243566.2 | 1.527E-8 | 0 | 89396 | gtex_brain_putamen_basal |
| rs1754181 | 7 | 76229194 | UPK3B | ENSG00000243566.2 | 1.537E-6 | 0 | 89449 | gtex_brain_putamen_basal |
| rs1754182 | 7 | 76229947 | UPK3B | ENSG00000243566.2 | 2.948E-11 | 0 | 90202 | gtex_brain_putamen_basal |
| rs10265902 | 7 | 76230140 | UPK3B | ENSG00000243566.2 | 4E-7 | 0 | 90395 | gtex_brain_putamen_basal |
| rs56237536 | 7 | 76230623 | UPK3B | ENSG00000243566.2 | 4.295E-10 | 0 | 90878 | gtex_brain_putamen_basal |
| rs1636645 | 7 | 76231596 | UPK3B | ENSG00000243566.2 | 6.687E-10 | 0 | 91851 | gtex_brain_putamen_basal |
| rs1636646 | 7 | 76231772 | UPK3B | ENSG00000243566.2 | 7.308E-7 | 0 | 92027 | gtex_brain_putamen_basal |
| rs189219383 | 7 | 76232817 | UPK3B | ENSG00000243566.2 | 5.287E-7 | 0 | 93072 | gtex_brain_putamen_basal |
| rs138598428 | 7 | 76234639 | UPK3B | ENSG00000243566.2 | 1.567E-9 | 0 | 94894 | gtex_brain_putamen_basal |
| rs1754191 | 7 | 76235700 | UPK3B | ENSG00000243566.2 | 2.147E-7 | 0 | 95955 | gtex_brain_putamen_basal |
| rs2462298 | 7 | 76236740 | UPK3B | ENSG00000243566.2 | 1.29E-8 | 0 | 96995 | gtex_brain_putamen_basal |
| rs1754196 | 7 | 76236751 | UPK3B | ENSG00000243566.2 | 6.001E-8 | 0 | 97006 | gtex_brain_putamen_basal |
| rs60316672 | 7 | 76236880 | UPK3B | ENSG00000243566.2 | 8.782E-12 | 0 | 97135 | gtex_brain_putamen_basal |
| rs62478039 | 7 | 76237030 | UPK3B | ENSG00000243566.2 | 7.359E-8 | 0 | 97285 | gtex_brain_putamen_basal |
| rs711306 | 7 | 76239480 | UPK3B | ENSG00000243566.2 | 2.321E-8 | 0 | 99735 | gtex_brain_putamen_basal |
| rs1799146 | 7 | 76239703 | UPK3B | ENSG00000243566.2 | 6.132E-9 | 0 | 99958 | gtex_brain_putamen_basal |
| rs7792149 | 7 | 76240247 | UPK3B | ENSG00000243566.2 | 1.077E-8 | 0 | 100502 | gtex_brain_putamen_basal |
| rs7808670 | 7 | 76240459 | UPK3B | ENSG00000243566.2 | 1.299E-9 | 0 | 100714 | gtex_brain_putamen_basal |
| rs1799210 | 7 | 76240529 | UPK3B | ENSG00000243566.2 | 2.589E-7 | 0 | 100784 | gtex_brain_putamen_basal |
| rs1799211 | 7 | 76240677 | UPK3B | ENSG00000243566.2 | 1.066E-6 | 0 | 100932 | gtex_brain_putamen_basal |
| rs71819724 | 7 | 76240785 | UPK3B | ENSG00000243566.2 | 5.689E-9 | 0 | 101040 | gtex_brain_putamen_basal |
| rs62475904 | 7 | 76241211 | UPK3B | ENSG00000243566.2 | 7.598E-9 | 0 | 101466 | gtex_brain_putamen_basal |
| rs55764248 | 7 | 76241216 | UPK3B | ENSG00000243566.2 | 7.595E-9 | 0 | 101471 | gtex_brain_putamen_basal |
| rs1638147 | 7 | 76245478 | UPK3B | ENSG00000243566.2 | 5.566E-7 | 0 | 105733 | gtex_brain_putamen_basal |
| rs1636620 | 7 | 76247805 | UPK3B | ENSG00000243566.2 | 2.029E-10 | 0 | 108060 | gtex_brain_putamen_basal |
| rs1799226 | 7 | 76248624 | UPK3B | ENSG00000243566.2 | 2.718E-8 | 0 | 108879 | gtex_brain_putamen_basal |
| rs72105261 | 7 | 76248704 | UPK3B | ENSG00000243566.2 | 1.344E-8 | 0 | 108959 | gtex_brain_putamen_basal |
| rs62475936 | 7 | 76249329 | UPK3B | ENSG00000243566.2 | 6.058E-8 | 0 | 109584 | gtex_brain_putamen_basal |
| rs62475938 | 7 | 76249808 | UPK3B | ENSG00000243566.2 | 1.996E-9 | 0 | 110063 | gtex_brain_putamen_basal |
| rs1754214 | 7 | 76249895 | UPK3B | ENSG00000243566.2 | 4.013E-10 | 0 | 110150 | gtex_brain_putamen_basal |
| rs62475940 | 7 | 76250292 | UPK3B | ENSG00000243566.2 | 1.775E-6 | 0 | 110547 | gtex_brain_putamen_basal |
| rs1636627 | 7 | 76250789 | UPK3B | ENSG00000243566.2 | 4.15E-12 | 0 | 111044 | gtex_brain_putamen_basal |
| rs1799231 | 7 | 76250806 | UPK3B | ENSG00000243566.2 | 1.613E-8 | 0 | 111061 | gtex_brain_putamen_basal |
| rs1754218 | 7 | 76251126 | UPK3B | ENSG00000243566.2 | 3.13E-8 | 0 | 111381 | gtex_brain_putamen_basal |
| rs77156628 | 7 | 76251842 | UPK3B | ENSG00000243566.2 | 2.747E-10 | 0 | 112097 | gtex_brain_putamen_basal |
| rs1799232 | 7 | 76252547 | UPK3B | ENSG00000243566.2 | 1.463E-8 | 0 | 112802 | gtex_brain_putamen_basal |
| rs1638113 | 7 | 76252630 | UPK3B | ENSG00000243566.2 | 3.861E-9 | 0 | 112885 | gtex_brain_putamen_basal |
| rs1799233 | 7 | 76253066 | UPK3B | ENSG00000243566.2 | 1.177E-8 | 0 | 113321 | gtex_brain_putamen_basal |
| rs1636630 | 7 | 76253315 | UPK3B | ENSG00000243566.2 | 3.353E-7 | 0 | 113570 | gtex_brain_putamen_basal |
| rs1799236 | 7 | 76254014 | UPK3B | ENSG00000243566.2 | 1.258E-7 | 0 | 114269 | gtex_brain_putamen_basal |
| rs2527933 | 7 | 76254332 | UPK3B | ENSG00000243566.2 | 6.303E-8 | 0 | 114587 | gtex_brain_putamen_basal |
| rs2480243 | 7 | 76254672 | UPK3B | ENSG00000243566.2 | 2.505E-9 | 0 | 114927 | gtex_brain_putamen_basal |
| rs62476705 | 7 | 76260534 | UPK3B | ENSG00000243566.2 | 1.743E-6 | 0 | 120789 | gtex_brain_putamen_basal |
| rs62473767 | 7 | 76264697 | UPK3B | ENSG00000243566.2 | 4.578E-7 | 0 | 124952 | gtex_brain_putamen_basal |
| rs62473768 | 7 | 76264698 | UPK3B | ENSG00000243566.2 | 6.44E-7 | 0 | 124953 | gtex_brain_putamen_basal |
| rs73365257 | 7 | 76266035 | UPK3B | ENSG00000243566.2 | 1.932E-10 | 0 | 126290 | gtex_brain_putamen_basal |
| rs200689025 | 7 | 76267565 | UPK3B | ENSG00000243566.2 | 2.302E-9 | 0 | 127820 | gtex_brain_putamen_basal |
| rs1636634 | 7 | 76268277 | UPK3B | ENSG00000243566.2 | 2.73E-9 | 0 | 128532 | gtex_brain_putamen_basal |
| rs62473776 | 7 | 76272786 | UPK3B | ENSG00000243566.2 | 1.58E-6 | 0 | 133041 | gtex_brain_putamen_basal |
| rs147316035 | 7 | 76274121 | UPK3B | ENSG00000243566.2 | 6.473E-7 | 0 | 134376 | gtex_brain_putamen_basal |
| rs147693721 | 7 | 76274286 | UPK3B | ENSG00000243566.2 | 2.862E-9 | 0 | 134541 | gtex_brain_putamen_basal |
| rs199919975 | 7 | 76275542 | UPK3B | ENSG00000243566.2 | 2.158E-6 | 0 | 135797 | gtex_brain_putamen_basal |
| rs62473783 | 7 | 76276132 | UPK3B | ENSG00000243566.2 | 6.337E-7 | 0 | 136387 | gtex_brain_putamen_basal |
| rs1292265 | 7 | 76280448 | UPK3B | ENSG00000243566.2 | 2.062E-8 | 0 | 140703 | gtex_brain_putamen_basal |
| rs77649064 | 7 | 76283327 | UPK3B | ENSG00000243566.2 | 1.147E-6 | 0 | 143582 | gtex_brain_putamen_basal |
| rs3852312 | 7 | 76311520 | UPK3B | ENSG00000243566.2 | 1.224E-7 | 0 | 171775 | gtex_brain_putamen_basal |
| rs62473850 | 7 | 76312934 | UPK3B | ENSG00000243566.2 | 7.898E-8 | 0 | 173189 | gtex_brain_putamen_basal |
| rs3864581 | 7 | 76316484 | UPK3B | ENSG00000243566.2 | 1E-7 | 0 | 176739 | gtex_brain_putamen_basal |
| rs10257644 | 7 | 76325810 | UPK3B | ENSG00000243566.2 | 4.378E-7 | 0 | 186065 | gtex_brain_putamen_basal |
| rs38709 | 7 | 76357838 | UPK3B | ENSG00000243566.2 | 3.169E-8 | 0 | 218093 | gtex_brain_putamen_basal |
| rs62475031 | 7 | 76379476 | UPK3B | ENSG00000243566.2 | 1.783E-6 | 0 | 239731 | gtex_brain_putamen_basal |
| rs117953357 | 7 | 76380613 | UPK3B | ENSG00000243566.2 | 1.725E-6 | 0 | 240868 | gtex_brain_putamen_basal |
| rs142065576 | 7 | 76382277 | UPK3B | ENSG00000243566.2 | 7.651E-7 | 0 | 242532 | gtex_brain_putamen_basal |
| rs55876699 | 7 | 76382321 | UPK3B | ENSG00000243566.2 | 8.005E-7 | 0 | 242576 | gtex_brain_putamen_basal |
| rs38663 | 7 | 76392620 | UPK3B | ENSG00000243566.2 | 1.593E-7 | 0 | 252875 | gtex_brain_putamen_basal |
| rs38659 | 7 | 76395981 | UPK3B | ENSG00000243566.2 | 9.974E-7 | 0 | 256236 | gtex_brain_putamen_basal |
| rs73142062 | 7 | 76399566 | UPK3B | ENSG00000243566.2 | 1.404E-6 | 0 | 259821 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PILRB | 0.72 | 0.68 |
| AP1G2 | 0.71 | 0.74 |
| NSUN5B | 0.71 | 0.69 |
| MYO15B | 0.69 | 0.67 |
| SEC31B | 0.69 | 0.67 |
| SCNN1D | 0.69 | 0.70 |
| NSUN5C | 0.69 | 0.69 |
| CES8 | 0.68 | 0.68 |
| AC022382.1 | 0.68 | 0.62 |
| CYP2D7P1 | 0.68 | 0.62 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HSPA13 | -0.30 | -0.29 |
| ABCD2 | -0.29 | -0.28 |
| CAV1 | -0.29 | -0.30 |
| TM4SF18 | -0.29 | -0.27 |
| PNPLA8 | -0.28 | -0.33 |
| ELTD1 | -0.28 | -0.27 |
| AGPS | -0.28 | -0.29 |
| TTC33 | -0.28 | -0.28 |
| FAM8A1 | -0.28 | -0.26 |
| TRAM1 | -0.28 | -0.36 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| MARKEY RB1 CHRONIC LOF DN | 118 | 78 | All SZGR 2.0 genes in this pathway |
| GAUSSMANN MLL AF4 FUSION TARGETS A DN | 90 | 61 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
| BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL TRANS | 185 | 114 | All SZGR 2.0 genes in this pathway |
| SWEET LUNG CANCER KRAS DN | 435 | 289 | All SZGR 2.0 genes in this pathway |
| LOPEZ EPITHELIOID MESOTHELIOMA | 17 | 11 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 9 | 76 | 45 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |