Gene Page: CHST9
Summary ?
| GeneID | 83539 |
| Symbol | CHST9 |
| Synonyms | GALNAC4ST-2|GalNAc4ST2 |
| Description | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 |
| Reference | MIM:610191|HGNC:HGNC:19898|Ensembl:ENSG00000154080|Vega:OTTHUMG00000179469 |
| Gene type | protein-coding |
| Map location | 18q11.2 |
| Pascal p-value | 0.169 |
| Fetal beta | 0.688 |
| eGene | Nucleus accumbens basal ganglia Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TCEB2 | 0.88 | 0.82 |
| TMEM147 | 0.86 | 0.85 |
| CHCHD5 | 0.85 | 0.79 |
| SSR4 | 0.85 | 0.78 |
| AP000350.6 | 0.84 | 0.77 |
| NDUFA11 | 0.84 | 0.76 |
| POLR2I | 0.83 | 0.77 |
| C7orf55 | 0.83 | 0.80 |
| YIF1A | 0.83 | 0.79 |
| TRPT1 | 0.83 | 0.74 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TRIM44 | -0.42 | -0.47 |
| AL031003.1 | -0.41 | -0.40 |
| VPS13A | -0.41 | -0.41 |
| RABGAP1L | -0.41 | -0.39 |
| USP12 | -0.41 | -0.40 |
| MYSM1 | -0.40 | -0.41 |
| TRAF3IP1 | -0.40 | -0.39 |
| KIF5C | -0.40 | -0.39 |
| SLK | -0.40 | -0.41 |
| AP000758.2 | -0.39 | -0.41 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 21 | 15 | All SZGR 2.0 genes in this pathway |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 49 | 33 | All SZGR 2.0 genes in this pathway |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 111 | 69 | All SZGR 2.0 genes in this pathway |
| REACTOME METABOLISM OF CARBOHYDRATES | 247 | 154 | All SZGR 2.0 genes in this pathway |
| SENGUPTA NASOPHARYNGEAL CARCINOMA DN | 349 | 157 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| HAMAI APOPTOSIS VIA TRAIL UP | 584 | 356 | All SZGR 2.0 genes in this pathway |
| SCHAEFFER PROSTATE DEVELOPMENT 48HR DN | 428 | 306 | All SZGR 2.0 genes in this pathway |
| PHESSE TARGETS OF APC AND MBD2 UP | 20 | 14 | All SZGR 2.0 genes in this pathway |