Gene Page: TRPT1
Summary ?
GeneID | 83707 |
Symbol | TRPT1 |
Synonyms | - |
Description | tRNA phosphotransferase 1 |
Reference | MIM:610470|HGNC:HGNC:20316|Ensembl:ENSG00000149743|HPRD:17479|Vega:OTTHUMG00000167844 |
Gene type | protein-coding |
Map location | 11q13.1 |
Pascal p-value | 0.013 |
eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs61761262 | 11 | 64000802 | TRPT1 | ENSG00000149743.9 | 1.4828E-6 | 0.01 | -7460 | gtex_brain_ba24 |
rs372192580 | 11 | 64016078 | TRPT1 | ENSG00000149743.9 | 7.56931E-7 | 0.01 | -22736 | gtex_brain_ba24 |
rs1806967 | 11 | 64078943 | TRPT1 | ENSG00000149743.9 | 1.87157E-6 | 0.01 | -85601 | gtex_brain_ba24 |
rs4930698 | 11 | 64085063 | TRPT1 | ENSG00000149743.9 | 1.77259E-6 | 0.01 | -91721 | gtex_brain_ba24 |
rs79423518 | 11 | 64105454 | TRPT1 | ENSG00000149743.9 | 1.70066E-6 | 0.01 | -112112 | gtex_brain_ba24 |
rs4930323 | 11 | 64153749 | TRPT1 | ENSG00000149743.9 | 1.90641E-6 | 0.01 | -160407 | gtex_brain_ba24 |
rs2083710 | 11 | 64168813 | TRPT1 | ENSG00000149743.9 | 5.41152E-7 | 0.01 | -175471 | gtex_brain_ba24 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RFNG | 0.85 | 0.82 |
CENPT | 0.84 | 0.87 |
CDK10 | 0.84 | 0.84 |
NCAPH2 | 0.84 | 0.85 |
HDAC10 | 0.84 | 0.85 |
RPS6KB2 | 0.84 | 0.83 |
TRMT1 | 0.83 | 0.82 |
FAM113A | 0.83 | 0.83 |
RP3-402G11.1 | 0.82 | 0.77 |
ARRDC1 | 0.82 | 0.80 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MT-CYB | -0.60 | -0.60 |
AF347015.27 | -0.60 | -0.60 |
AF347015.8 | -0.59 | -0.60 |
AF347015.15 | -0.59 | -0.59 |
AF347015.33 | -0.58 | -0.57 |
MT-CO2 | -0.58 | -0.57 |
AF347015.31 | -0.58 | -0.57 |
AF347015.26 | -0.57 | -0.60 |
AF347015.2 | -0.57 | -0.57 |
MT-ATP8 | -0.55 | -0.64 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN | 634 | 384 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
PASQUALUCCI LYMPHOMA BY GC STAGE UP | 283 | 177 | All SZGR 2.0 genes in this pathway |
ZWANG EGF PERSISTENTLY DN | 61 | 36 | All SZGR 2.0 genes in this pathway |