Gene Page: THOC5

Summary
GeneID  8563
Symbol  THOC5
Synonyms  C22orf19|Fmip|PK1.3|fSAP79
Description  THO complex 5
See related  HGNC:19074|Ensembl:ENSG00000100296|HPRD:16650|
Locus tag  -
Gene type  protein-coding
Map location  22q12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LDB30.950.87
TF0.940.85
NIPAL40.940.86
ATPGD10.940.88
FA2H0.940.85
KLK60.940.84
LDLRAP10.930.81
SLC5A110.930.89
RHBDL20.920.85
CNP0.920.86
Top 10 negatively co-expressed genes
NKIRAS2-0.50-0.53
POLB-0.49-0.62
HN1-0.49-0.58
IFT52-0.49-0.61
RPL12-0.49-0.71
MED19-0.48-0.56
STMN1-0.48-0.57
RPSA-0.48-0.69
RARS2-0.48-0.59
AC009133.1-0.48-0.56
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030154cell differentiationIEA-
GO:0045650negative regulation of macrophage differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSF1RC-FMS | CD115 | CSFR | FIM2 | FMScolony stimulating factor 1 receptor-HPRD10597251 
ESR1DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1estrogen receptor 1ER interacts with C22orf19.BIND16009131 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_UP 9858All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR 14984All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway


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