Gene Page: DCAF5
Summary ?
| GeneID | 8816 |
| Symbol | DCAF5 |
| Synonyms | BCRG2|BCRP2|D14S1461E|WDR22 |
| Description | DDB1 and CUL4 associated factor 5 |
| Reference | MIM:603812|HGNC:HGNC:20224|Ensembl:ENSG00000139990|HPRD:16032|Vega:OTTHUMG00000171699 |
| Gene type | protein-coding |
| Map location | 14q24.1 |
| Pascal p-value | 0.041 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GNA13 | 0.93 | 0.91 |
| G3BP1 | 0.91 | 0.85 |
| ADH5 | 0.90 | 0.81 |
| SMAD4 | 0.89 | 0.82 |
| RBBP4 | 0.88 | 0.78 |
| UNG | 0.88 | 0.84 |
| PPM1D | 0.88 | 0.79 |
| STAG2 | 0.88 | 0.85 |
| GNAI3 | 0.88 | 0.81 |
| HAUS6 | 0.88 | 0.86 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SLC9A3R2 | -0.54 | -0.51 |
| AC018755.7 | -0.52 | -0.59 |
| C5orf53 | -0.51 | -0.57 |
| MT-CO2 | -0.50 | -0.64 |
| IFI27 | -0.49 | -0.65 |
| AF347015.27 | -0.48 | -0.59 |
| AF347015.33 | -0.48 | -0.59 |
| FXYD1 | -0.48 | -0.61 |
| HLA-F | -0.48 | -0.51 |
| AF347015.31 | -0.47 | -0.60 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL LONG TERM | 302 | 191 | All SZGR 2.0 genes in this pathway |
| CUI TCF21 TARGETS 2 DN | 830 | 547 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 | 482 | 296 | All SZGR 2.0 genes in this pathway |
| SANSOM APC MYC TARGETS | 217 | 138 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA | 43 | 27 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA CHEMOTAXIS UP | 74 | 45 | All SZGR 2.0 genes in this pathway |
| MILI PSEUDOPODIA HAPTOTAXIS UP | 518 | 299 | All SZGR 2.0 genes in this pathway |