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| GeneID |
8940
|
| Symbol |
TOP3B
|
| Synonyms |
FLJ39376
|
| Description |
topoisomerase (DNA) III beta |
| See related |
HGNC:11993|MIM:603582|Ensembl:ENSG00000100038|HPRD:04662| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
22q11.22 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.031 | |
|
| |
| General Gene Expression (microarray) ? |
|
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| ACTR3 | 0.94 | 0.95 | | |
| PSPC1 | 0.93 | 0.94 | | |
| CCT5 | 0.93 | 0.93 | | |
| GSPT2 | 0.92 | 0.94 | | |
| ARF4 | 0.92 | 0.92 | | |
| PLAA | 0.92 | 0.92 | | |
| RAB10 | 0.92 | 0.92 | | |
| YWHAQ | 0.92 | 0.93 | | |
| ARMCX5 | 0.92 | 0.92 | | |
| GLOD4 | 0.92 | 0.92 | | |
Top 10 negatively co-expressed genes | | MT-CO2 | -0.81 | -0.86 | | |
| AF347015.33 | -0.79 | -0.85 | | |
| FXYD1 | -0.78 | -0.84 | | |
| AF347015.31 | -0.78 | -0.84 | | |
| AF347015.8 | -0.78 | -0.85 | | |
| AF347015.27 | -0.76 | -0.84 | | |
| MT-CYB | -0.76 | -0.83 | | |
| AF347015.21 | -0.75 | -0.84 | | |
| AF347015.2 | -0.75 | -0.84 | | |
| AF347015.15 | -0.74 | -0.84 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003917 | DNA topoisomerase type I activity | IEA | | - |
| GO:0005515 | protein binding | IPI | | 15231747 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006268 | DNA unwinding during replication | IEA | | - |
| GO:0006265 | DNA topological change | IEA | | - |
| GO:0007059 | chromosome segregation | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000793 | condensed chromosome | IEA | | - |
| GO:0005634 | nucleus | TAS | | 9786843 |
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