Gene Page: WFDC8
Summary ?
GeneID | 90199 |
Symbol | WFDC8 |
Synonyms | C20orf170|HEL-S-292|WAP8|dJ461P17.1 |
Description | WAP four-disulfide core domain 8 |
Reference | HGNC:HGNC:16163|Ensembl:ENSG00000158901|HPRD:11685|Vega:OTTHUMG00000046342 |
Gene type | protein-coding |
Map location | 20q13.12 |
Pascal p-value | 0.041 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
C16orf14 | 0.69 | 0.62 |
MRPL41 | 0.68 | 0.60 |
TRPT1 | 0.68 | 0.65 |
DCXR | 0.68 | 0.62 |
YIF1A | 0.67 | 0.61 |
KRTCAP2 | 0.66 | 0.63 |
TMEM134 | 0.66 | 0.66 |
DCI | 0.66 | 0.64 |
DNAJC4 | 0.65 | 0.67 |
MPG | 0.65 | 0.54 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RABGAP1L | -0.55 | -0.59 |
CCDC75 | -0.54 | -0.59 |
DENND4A | -0.54 | -0.58 |
C10orf118 | -0.54 | -0.59 |
FMR1 | -0.54 | -0.56 |
NUCKS1 | -0.54 | -0.60 |
PPP1R12A | -0.54 | -0.56 |
RANBP2 | -0.54 | -0.58 |
AP000758.2 | -0.53 | -0.58 |
PITPNB | -0.53 | -0.58 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |