Gene Page: PRPF3

Summary
GeneID  9129
Symbol  PRPF3
Synonyms  HPRP3|HPRP3P|PRP3|Prp3p|RP18
Description  PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)
See related  HGNC:17348|MIM:607301|Ensembl:ENSG00000117360|HPRD:07389|
Locus tag  -
Gene type  protein-coding
Map location  1q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
VWA5B20.780.75
ARHGEF40.770.74
PDE4C0.770.75
SHANK30.750.80
DGKZ0.750.72
KCNIP30.750.73
SAPS10.750.72
PACSIN10.740.74
SYT150.740.77
FMNL10.740.68
Top 10 negatively co-expressed genes
RPS6-0.52-0.63
RPL24-0.51-0.64
C9orf46-0.51-0.58
RPS13P2-0.50-0.59
RPS18-0.50-0.60
RPS3AP47-0.50-0.56
RPL27-0.50-0.61
RPL5-0.50-0.54
AC079354.7-0.50-0.52
RPS23-0.50-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16189514 |17353931 
GO:0031202RNA splicing factor activity, transesterification mechanismTAS9328476 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000398nuclear mRNA splicing, via spliceosomeNAS9328476 
GO:0008380RNA splicingTAS9328476 
GO:0007601visual perceptionIEA-
GO:0050896response to stimulusIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS9328476 
GO:0005681spliceosomeNAS9328476 
GO:0016607nuclear speckIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
DPY30HDPY-30 | Saf19dpy-30 homolog (C. elegans)Two-hybridBioGRID16189514 
DVL2-dishevelled, dsh homolog 2 (Drosophila)Two-hybridBioGRID16189514 
DVL3KIAA0208dishevelled, dsh homolog 3 (Drosophila)Affinity Capture-Western
Two-hybrid
BioGRID16189514 
GTPBP3FLJ14700 | GTPBG3 | MSS1 | MTGP1 | THDF1GTP binding protein 3 (mitochondrial)Two-hybridBioGRID16189514 
RNPS1E5.1 | MGC117332RNA binding protein S1, serine-rich domainAffinity Capture-MSBioGRID17353931 
SART3DSAP1 | KIAA0156 | MGC138188 | P100 | RP11-13G14 | TIP110 | p110 | p110(nrb)squamous cell carcinoma antigen recognized by T cells 3-HPRD,BioGRID12374753 |15452143 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_UP 290177All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP 191128All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA 5031All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP 156101All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
WEST_ADRENOCORTICAL_CARCINOMA_VS_ADENOMA_UP 2113All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP 223132All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway


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