Gene Page: ZNF830
Summary ?
| GeneID | 91603 |
| Symbol | ZNF830 |
| Synonyms | CCDC16|OMCG1 |
| Description | zinc finger protein 830 |
| Reference | HGNC:HGNC:28291|HPRD:14469| |
| Gene type | protein-coding |
| Map location | 17q12 |
| Pascal p-value | 0.048 |
| Sherlock p-value | 0.939 |
| DMG | 1 (# studies) |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Jaffe_2016 | Genome-wide DNA methylation analysis | This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg00367659 | 17 | 33288544 | ZNF830 | 5.52E-10 | -0.032 | 8.9E-7 | DMG:Jaffe_2016 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs4951059 | chr1 | 204258018 | ZNF830 | 91603 | 0.06 | trans | ||
| rs841285 | chr2 | 129330728 | ZNF830 | 91603 | 0.14 | trans | ||
| rs1155107 | chr3 | 26843376 | ZNF830 | 91603 | 0.11 | trans | ||
| rs1395163 | chr3 | 31028951 | ZNF830 | 91603 | 0.08 | trans | ||
| rs17029291 | chr3 | 32402138 | ZNF830 | 91603 | 0.01 | trans | ||
| rs830202 | chr3 | 165654796 | ZNF830 | 91603 | 0.11 | trans | ||
| rs16870339 | chr5 | 2705169 | ZNF830 | 91603 | 0.04 | trans | ||
| rs4617108 | chr7 | 49423831 | ZNF830 | 91603 | 0.1 | trans | ||
| rs3779536 | chr7 | 127233976 | ZNF830 | 91603 | 0.03 | trans | ||
| rs1954396 | chr14 | 43601835 | ZNF830 | 91603 | 0.06 | trans | ||
| rs4901739 | chr14 | 57345856 | ZNF830 | 91603 | 0.19 | trans | ||
| rs12441507 | chr15 | 61484028 | ZNF830 | 91603 | 0.18 | trans | ||
| rs1761450 | chr19 | 54818034 | ZNF830 | 91603 | 0.05 | trans | ||
| rs16996420 | chr20 | 9780867 | ZNF830 | 91603 | 0.14 | trans | ||
| rs6098023 | chr20 | 53113740 | ZNF830 | 91603 | 0.02 | trans | ||
| rs12157904 | chr22 | 37982011 | ZNF830 | 91603 | 0.19 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DARWICHE SKIN TUMOR PROMOTER DN | 185 | 115 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK LOW DN | 165 | 107 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK HIGH DN | 180 | 110 | All SZGR 2.0 genes in this pathway |
| DARWICHE SQUAMOUS CELL CARCINOMA DN | 181 | 107 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS EARLY PROGENITOR | 532 | 309 | All SZGR 2.0 genes in this pathway |