Gene Page: NCOR2
Summary ?
GeneID | 9612 |
Symbol | NCOR2 |
Synonyms | CTG26|N-CoR2|SMAP270|SMRT|SMRTE|SMRTE-tau|TNRC14|TRAC|TRAC-1|TRAC1 |
Description | nuclear receptor corepressor 2 |
Reference | MIM:600848|HGNC:HGNC:7673|Ensembl:ENSG00000196498|HPRD:02910|Vega:OTTHUMG00000150455 |
Gene type | protein-coding |
Map location | 12q24 |
Pascal p-value | 0.008 |
Sherlock p-value | 0.704 |
Fetal beta | -0.704 |
DMG | 2 (# studies) |
eGene | Myers' cis & trans |
Support | CompositeSet Darnell FMRP targets |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
DMG:Montano_2016 | Genome-wide DNA methylation analysis | This dataset includes 172 replicated associations between CpGs with schizophrenia. | 6 |
DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 6 |
DNM:Gulsuner_2013 | Whole Exome Sequencing analysis | 155 DNMs identified by exome sequencing of quads or trios of schizophrenia individuals and their parents. |
Section I. Genetics and epigenetics annotation
DNM table
Gene | Chromosome | Position | Ref | Alt | Transcript | AA change | Mutation type | Sift | CG46 | Trait | Study |
---|---|---|---|---|---|---|---|---|---|---|---|
NCOR2 | chr12 | 124856705 | C | T | NM_001077261 NM_001206654 NM_006312 | . . . | silent silent silent | Schizophrenia | DNM:Fromer_2014 | ||
NCOR2 | chr12 | 124821527 | G | A | NM_001077261 NM_001206654 NM_006312 | p.1953R>C p.1953R>C p.1963R>C | missense missense missense | Schizophrenia | DNM:Gulsuner_2013 |
Differentially methylated gene
Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
---|---|---|---|---|---|---|---|
cg26385126 | 12 | 124912021 | NCOR2 | 4.99E-7 | 0.006 | 0.014 | DMG:Montano_2016 |
cg27431877 | 12 | 124911924 | NCOR2 | 2.29E-5 | 0.005 | 0.066 | DMG:Montano_2016 |
cg11311053 | 12 | 124912049 | NCOR2 | 6.7E-5 | 0.006 | 0.105 | DMG:Montano_2016 |
ch.12.2647993F | 12 | 124837365 | NCOR2 | 1.157E-4 | -0.649 | 0.029 | DMG:Wockner_2014 |
cg26385126 | 12 | 124912021 | NCOR2 | 2.517E-4 | 0.489 | 0.037 | DMG:Wockner_2014 |
cg09942210 | 12 | 124965227 | NCOR2 | 3.422E-4 | -0.48 | 0.041 | DMG:Wockner_2014 |
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs11057881 | chr12 | 125371972 | NCOR2 | 9612 | 0.09 | cis | ||
rs13297121 | chr9 | 71994881 | NCOR2 | 9612 | 0.1 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|---|---|---|---|
GO:0004872 | receptor activity | IEA | - | |
GO:0003677 | DNA binding | IEA | - | |
GO:0003714 | transcription corepressor activity | TAS | 7566127 | |
GO:0005112 | Notch binding | IPI | 10713164 | |
GO:0005515 | protein binding | IPI | 10713164 |15016912 | |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | - | |
GO:0045449 | regulation of transcription | IEA | - | |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
GO:0005634 | nucleus | TAS | 10097068 | |
GO:0005730 | nucleolus | IDA | 18029348 |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
---|---|---|---|---|---|
AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | Affinity Capture-Western Co-localization Reconstituted Complex Two-hybrid | BioGRID | 11923464 |12441355 |14593076 |
BCL6 | BCL5 | BCL6A | LAZ3 | ZBTB27 | ZNF51 | B-cell CLL/lymphoma 6 | - | HPRD,BioGRID | 9765306 |
BCL6 | BCL5 | BCL6A | LAZ3 | ZBTB27 | ZNF51 | B-cell CLL/lymphoma 6 | The lateral groove motif in the BTB domain of BCL6 interacts with the BBD motif of SMRT. | BIND | 15531890 |
BIRC3 | AIP1 | API2 | CIAP2 | HAIP1 | HIAP1 | MALT2 | MIHC | RNF49 | baculoviral IAP repeat-containing 3 | The cIAP-2 promoter interacts with SMRT. | BIND | 15494311 |
CBFA2T2 | DKFZp313F2116 | EHT | MTGR1 | ZMYND3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | - | HPRD | 12242670 |
CCL3 | G0S19-1 | LD78ALPHA | MIP-1-alpha | MIP1A | SCYA3 | chemokine (C-C motif) ligand 3 | SMRT interacts with the CCL3 promoter region. | BIND | 15531890 |
CCND2 | KIAK0002 | MGC102758 | cyclin D2 | SMRT interacts with the CCND2 promoter region. | BIND | 15531890 |
CDKN2A | ARF | CDK4I | CDKN2 | CMM2 | INK4 | INK4a | MLM | MTS1 | TP16 | p14 | p14ARF | p16 | p16INK4 | p16INK4a | p19 | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | NCOR2 (SMRT) interacts with p-p14(ARF) (p14(ARF) promoter). | BIND | 15729358 |
CHUK | IKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16 | conserved helix-loop-helix ubiquitous kinase | IKK-alpha phosphorylates SMRT. | BIND | 15494311 |
CIR | - | CBF1 interacting corepressor | - | HPRD,BioGRID | 11509665 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | ESR1 (ER-alpha) interacts with NCOR2 (SMRT). This interaction was modeled on a demonstrated interaction between ESR1 from an unspecified species and NCOR2 from an unspecified species. | BIND | 12738788 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | - | HPRD | 9702189 |
FOS | AP-1 | C-FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | - | HPRD,BioGRID | 10777532 |
HDAC1 | DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1 | histone deacetylase 1 | Affinity Capture-Western Co-purification | BioGRID | 11013263 |11739383 |
HDAC10 | DKFZp761B039 | MGC149722 | histone deacetylase 10 | - | HPRD,BioGRID | 11739383 |
HDAC2 | RPD3 | YAF1 | histone deacetylase 2 | Co-purification | BioGRID | 11013263 |
HDAC3 | HD3 | RPD3 | RPD3-2 | histone deacetylase 3 | Affinity Capture-MS Affinity Capture-Western Co-fractionation Co-purification Reconstituted Complex | BioGRID | 10809664 |10944117 |11013263 |11804585 |12502735 |12628926 |14527417 |
HDAC4 | HA6116 | HD4 | HDAC-A | HDACA | KIAA0288 | histone deacetylase 4 | - | HPRD,BioGRID | 11804585 |
HDAC5 | FLJ90614 | HD5 | NY-CO-9 | histone deacetylase 5 | - | HPRD | 10869435 |
HDAC5 | FLJ90614 | HD5 | NY-CO-9 | histone deacetylase 5 | Reconstituted Complex Two-hybrid | BioGRID | 10640275 |
HDAC7 | DKFZp586J0917 | FLJ99588 | HD7A | HDAC7A | histone deacetylase 7 | Affinity Capture-Western | BioGRID | 11466315 |
IKZF1 | Hs.54452 | IK1 | IKAROS | LYF1 | PRO0758 | ZNFN1A1 | hIk-1 | IKAROS family zinc finger 1 (Ikaros) | Affinity Capture-Western | BioGRID | 11959865 |
IL8 | CXCL8 | GCP-1 | GCP1 | LECT | LUCT | LYNAP | MDNCF | MONAP | NAF | NAP-1 | NAP1 | interleukin 8 | The IL-8 promoter interacts with SMRT. | BIND | 15494311 |
INPP5K | PPS | SKIP | inositol polyphosphate-5-phosphatase K | Two-hybrid | BioGRID | 11509665 |
JUN | AP-1 | AP1 | c-Jun | jun oncogene | Reconstituted Complex Two-hybrid | BioGRID | 10777532 |
MYBL2 | B-MYB | BMYB | MGC15600 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | - | HPRD | 11997503 |
MYOD1 | MYF3 | MYOD | PUM | bHLHc1 | myogenic differentiation 1 | - | HPRD | 10406466 |
NCOA3 | ACTR | AIB-1 | AIB1 | CAGH16 | CTG26 | KAT13B | MGC141848 | RAC3 | SRC3 | TNRC14 | TNRC16 | TRAM-1 | pCIP | nuclear receptor coactivator 3 | - | HPRD | 9267036 |
NCOR1 | KIAA1047 | MGC104216 | N-CoR | TRAC1 | hCIT529I10 | hN-CoR | nuclear receptor co-repressor 1 | Co-fractionation | BioGRID | 10944117 |
NFKB1 | DKFZp686C01211 | EBP-1 | KBF1 | MGC54151 | NF-kappa-B | NFKB-p105 | NFKB-p50 | p105 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | - | HPRD | 10777532 |
NFKBIA | IKBA | MAD-3 | NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | Affinity Capture-Western | BioGRID | 12589049 |
NR3C1 | GCCR | GCR | GR | GRL | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | - | HPRD,BioGRID | 12011091 |
NR4A1 | GFRP1 | HMR | MGC9485 | N10 | NAK-1 | NGFIB | NP10 | NUR77 | TR3 | nuclear receptor subfamily 4, group A, member 1 | - | HPRD,BioGRID | 11559707 |
PML | MYL | PP8675 | RNF71 | TRIM19 | promyelocytic leukemia | - | HPRD,BioGRID | 11585900 |
POU2F1 | OCT1 | OTF1 | POU class 2 homeobox 1 | - | HPRD,BioGRID | 11134019 |
PPARA | MGC2237 | MGC2452 | NR1C1 | PPAR | hPPAR | peroxisome proliferator-activated receptor alpha | - | HPRD,BioGRID | 11845213 |
PPARD | FAAR | MGC3931 | NR1C2 | NUC1 | NUCI | NUCII | PPAR-beta | PPARB | peroxisome proliferator-activated receptor delta | - | HPRD,BioGRID | 11867749 |
PPARD | FAAR | MGC3931 | NR1C2 | NUC1 | NUCI | NUCII | PPAR-beta | PPARB | peroxisome proliferator-activated receptor delta | PPAR-delta interacts with SMRT. This interaction was modelled on a demonstrated interaction between PPAR-delta and SMRT from unspecified sources. | BIND | 12970571 |
RARA | NR1B1 | RAR | retinoic acid receptor, alpha | Affinity Capture-Western Reconstituted Complex | BioGRID | 9256429 |11929748 |
RARA | NR1B1 | RAR | retinoic acid receptor, alpha | NCOR2 (SMRT) interacts with p-RAR-alpha2 (RAR-alpha2 promoter). | BIND | 15729358 |
RBPJ | CBF1 | IGKJRB | IGKJRB1 | KBF2 | MGC61669 | RBP-J | RBPJK | RBPSUH | SUH | csl | recombination signal binding protein for immunoglobulin kappa J region | - | HPRD,BioGRID | 11509665 |
RELA | MGC131774 | NFKB3 | p65 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | - | HPRD,BioGRID | 12589049 |
RUNX1T1 | AML1T1 | CBFA2T1 | CDR | ETO | MGC2796 | MTG8 | MTG8b | ZMYND2 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | - | HPRD,BioGRID | 11113190 |
SAP30 | - | Sin3A-associated protein, 30kDa | - | HPRD | 9702189 |
SAP30 | - | Sin3A-associated protein, 30kDa | Co-purification | BioGRID | 11013263 |
SIN3A | DKFZp434K2235 | FLJ90319 | KIAA0700 | SIN3 homolog A, transcription regulator (yeast) | Co-fractionation Reconstituted Complex | BioGRID | 10640275 |10944117 |
SIRT1 | SIR2L1 | sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) | Sirt1 interacts with SMRT. | BIND | 15175761 |
SMARCA4 | BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2b | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Co-fractionation | BioGRID | 10944117 |
SNW1 | Bx42 | MGC119379 | NCOA-62 | PRPF45 | Prp45 | SKIIP | SKIP | SNW domain containing 1 | Affinity Capture-Western in vitro in vivo Two-hybrid | BioGRID | 10644367 |10713164 |
SNW1 | Bx42 | MGC119379 | NCOA-62 | PRPF45 | Prp45 | SKIIP | SKIP | SNW domain containing 1 | - | HPRD | 10713164 |11509665 |
SPEN | KIAA0929 | MINT | RP1-134O19.1 | SHARP | spen homolog, transcriptional regulator (Drosophila) | - | HPRD,BioGRID | 11331609 |
SRF | MCM1 | serum response factor (c-fos serum response element-binding transcription factor) | - | HPRD,BioGRID | 10777532 |
STAT5A | MGF | STAT5 | signal transducer and activator of transcription 5A | - | HPRD | 11726519 |
STAT5B | STAT5 | signal transducer and activator of transcription 5B | - | HPRD | 11726519 |
TBL1X | EBI | SMAP55 | TBL1 | transducin (beta)-like 1X-linked | - | HPRD,BioGRID | 10809664 |
THRB | ERBA-BETA | ERBA2 | GRTH | MGC126109 | MGC126110 | NR1A2 | PRTH | THR1 | THRB1 | THRB2 | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | Reconstituted Complex | BioGRID | 9751500 |
VDR | NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor | Reconstituted Complex | BioGRID | 12460926 |
YWHAE | 14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 14-3-3-epsilon interacts with SMRT. | BIND | 15494311 |
ZBTB16 | PLZF | ZNF145 | zinc finger and BTB domain containing 16 | - | HPRD | 9256429 |14982881 |
ZBTB16 | PLZF | ZNF145 | zinc finger and BTB domain containing 16 | Affinity Capture-Western Reconstituted Complex Two-hybrid | BioGRID | 9256429 |9765306 |14982881 |
ZBTB16 | PLZF | ZNF145 | zinc finger and BTB domain containing 16 | SMRT interacts with PLZF. This interaction was modelled on a demonstrated interaction between SMRT and PLZF from unspecified species. | BIND | 9486654 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG NOTCH SIGNALING PATHWAY | 47 | 35 | All SZGR 2.0 genes in this pathway |
BIOCARTA CARM ER PATHWAY | 35 | 27 | All SZGR 2.0 genes in this pathway |
BIOCARTA EGFR SMRTE PATHWAY | 11 | 11 | All SZGR 2.0 genes in this pathway |
BIOCARTA PPARA PATHWAY | 58 | 43 | All SZGR 2.0 genes in this pathway |
BIOCARTA ETS PATHWAY | 18 | 12 | All SZGR 2.0 genes in this pathway |
BIOCARTA RARRXR PATHWAY | 15 | 9 | All SZGR 2.0 genes in this pathway |
PID NOTCH PATHWAY | 59 | 49 | All SZGR 2.0 genes in this pathway |
PID HDAC CLASSII PATHWAY | 34 | 27 | All SZGR 2.0 genes in this pathway |
PID HDAC CLASSI PATHWAY | 66 | 50 | All SZGR 2.0 genes in this pathway |
PID RXR VDR PATHWAY | 26 | 24 | All SZGR 2.0 genes in this pathway |
PID ERA GENOMIC PATHWAY | 65 | 37 | All SZGR 2.0 genes in this pathway |
PID RETINOIC ACID PATHWAY | 30 | 23 | All SZGR 2.0 genes in this pathway |
PID HES HEY PATHWAY | 48 | 39 | All SZGR 2.0 genes in this pathway |
REACTOME DEVELOPMENTAL BIOLOGY | 396 | 292 | All SZGR 2.0 genes in this pathway |
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 46 | 28 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY NOTCH1 | 70 | 46 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 38 | 26 | All SZGR 2.0 genes in this pathway |
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 20 | 14 | All SZGR 2.0 genes in this pathway |
REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | 478 | 302 | All SZGR 2.0 genes in this pathway |
REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | 168 | 115 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 72 | 53 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY NOTCH | 103 | 64 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 63 | 42 | All SZGR 2.0 genes in this pathway |
HOLLMANN APOPTOSIS VIA CD40 UP | 201 | 125 | All SZGR 2.0 genes in this pathway |
GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN | 493 | 298 | All SZGR 2.0 genes in this pathway |
ZHOU INFLAMMATORY RESPONSE LIVE UP | 485 | 293 | All SZGR 2.0 genes in this pathway |
HOEBEKE LYMPHOID STEM CELL UP | 95 | 64 | All SZGR 2.0 genes in this pathway |
SENESE HDAC3 TARGETS DN | 536 | 332 | All SZGR 2.0 genes in this pathway |
KINSEY TARGETS OF EWSR1 FLII FUSION DN | 329 | 219 | All SZGR 2.0 genes in this pathway |
ENK UV RESPONSE EPIDERMIS DN | 508 | 354 | All SZGR 2.0 genes in this pathway |
SCHEIDEREIT IKK TARGETS | 18 | 15 | All SZGR 2.0 genes in this pathway |
MARTIN INTERACT WITH HDAC | 44 | 31 | All SZGR 2.0 genes in this pathway |
SCHLOSSER SERUM RESPONSE AUGMENTED BY MYC | 108 | 74 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN | 483 | 336 | All SZGR 2.0 genes in this pathway |
PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | 637 | 377 | All SZGR 2.0 genes in this pathway |
FERREIRA EWINGS SARCOMA UNSTABLE VS STABLE DN | 98 | 59 | All SZGR 2.0 genes in this pathway |
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN | 428 | 306 | All SZGR 2.0 genes in this pathway |
FLECHNER PBL KIDNEY TRANSPLANT OK VS DONOR UP | 151 | 100 | All SZGR 2.0 genes in this pathway |
KLEIN PRIMARY EFFUSION LYMPHOMA UP | 51 | 29 | All SZGR 2.0 genes in this pathway |
HSIAO LIVER SPECIFIC GENES | 244 | 154 | All SZGR 2.0 genes in this pathway |
THEILGAARD NEUTROPHIL AT SKIN WOUND UP | 77 | 52 | All SZGR 2.0 genes in this pathway |
MARTINEZ RESPONSE TO TRABECTEDIN | 50 | 32 | All SZGR 2.0 genes in this pathway |
NATSUME RESPONSE TO INTERFERON BETA DN | 52 | 33 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
SESTO RESPONSE TO UV C5 | 46 | 36 | All SZGR 2.0 genes in this pathway |
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 | 419 | 273 | All SZGR 2.0 genes in this pathway |
DOUGLAS BMI1 TARGETS UP | 566 | 371 | All SZGR 2.0 genes in this pathway |
MITSIADES RESPONSE TO APLIDIN UP | 439 | 257 | All SZGR 2.0 genes in this pathway |
HSIAO HOUSEKEEPING GENES | 389 | 245 | All SZGR 2.0 genes in this pathway |
MARTENS BOUND BY PML RARA FUSION | 456 | 287 | All SZGR 2.0 genes in this pathway |
PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
BHAT ESR1 TARGETS NOT VIA AKT1 UP | 211 | 131 | All SZGR 2.0 genes in this pathway |
BHAT ESR1 TARGETS VIA AKT1 UP | 281 | 183 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | miRNA seq | ||
---|---|---|---|---|---|
UTR start | UTR end | Match method | |||
miR-10 | 670 | 677 | 1A,m8 | hsa-miR-10a | UACCCUGUAGAUCCGAAUUUGUG |
hsa-miR-10b | UACCCUGUAGAACCGAAUUUGU | ||||
miR-124.1 | 169 | 175 | 1A | hsa-miR-124a | UUAAGGCACGCGGUGAAUGCCA |
miR-125/351 | 215 | 221 | m8 | hsa-miR-125bbrain | UCCCUGAGACCCUAACUUGUGA |
hsa-miR-125abrain | UCCCUGAGACCCUUUAACCUGUG | ||||
miR-184 | 136 | 143 | 1A,m8 | hsa-miR-184 | UGGACGGAGAACUGAUAAGGGU |
miR-29 | 232 | 238 | m8 | hsa-miR-29aSZ | UAGCACCAUCUGAAAUCGGUU |
hsa-miR-29bSZ | UAGCACCAUUUGAAAUCAGUGUU | ||||
hsa-miR-29cSZ | UAGCACCAUUUGAAAUCGGU | ||||
miR-30-5p | 224 | 230 | m8 | hsa-miR-30a-5p | UGUAAACAUCCUCGACUGGAAG |
hsa-miR-30cbrain | UGUAAACAUCCUACACUCUCAGC | ||||
hsa-miR-30dSZ | UGUAAACAUCCCCGACUGGAAG | ||||
hsa-miR-30bSZ | UGUAAACAUCCUACACUCAGCU | ||||
hsa-miR-30e-5p | UGUAAACAUCCUUGACUGGA | ||||
miR-331 | 217 | 223 | 1A | hsa-miR-331brain | GCCCCUGGGCCUAUCCUAGAA |
miR-9 | 377 | 383 | m8 | hsa-miR-9SZ | UCUUUGGUUAUCUAGCUGUAUGA |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.