Gene Page: MTL5
Summary ?
| GeneID | 9633 |
| Symbol | MTL5 |
| Synonyms | CXCDC2|MTLT|TESMIN |
| Description | metallothionein-like 5, testis-specific (tesmin) |
| Reference | MIM:604374|HGNC:HGNC:7446|Ensembl:ENSG00000132749|HPRD:09186|Vega:OTTHUMG00000167891 |
| Gene type | protein-coding |
| Map location | 11q13.3 |
| Pascal p-value | 0.018 |
| eGene | Nucleus accumbens basal ganglia |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZDHHC7 | 0.92 | 0.92 |
| TMEM127 | 0.91 | 0.91 |
| GBF1 | 0.91 | 0.91 |
| LARP4B | 0.90 | 0.90 |
| UBE3B | 0.90 | 0.90 |
| MTOR | 0.90 | 0.89 |
| UBE2O | 0.90 | 0.90 |
| ZDHHC5 | 0.90 | 0.89 |
| GGA3 | 0.89 | 0.90 |
| NPLOC4 | 0.89 | 0.88 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.76 | -0.73 |
| AF347015.31 | -0.73 | -0.68 |
| MT-CO2 | -0.73 | -0.68 |
| C1orf54 | -0.69 | -0.74 |
| AF347015.8 | -0.69 | -0.66 |
| HIGD1B | -0.69 | -0.64 |
| AF347015.33 | -0.67 | -0.61 |
| MT-CYB | -0.67 | -0.62 |
| FXYD1 | -0.67 | -0.62 |
| GNG11 | -0.67 | -0.65 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KIM WT1 TARGETS 8HR DN | 129 | 84 | All SZGR 2.0 genes in this pathway |
| FARMER BREAST CANCER APOCRINE VS LUMINAL | 326 | 213 | All SZGR 2.0 genes in this pathway |
| FARMER BREAST CANCER BASAL VS LULMINAL | 330 | 215 | All SZGR 2.0 genes in this pathway |
| LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL DN | 114 | 58 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 11Q12 Q14 AMPLICON | 158 | 93 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY MUTATED AND AMPLIFIED IN BREAST CANCER | 94 | 60 | All SZGR 2.0 genes in this pathway |
| RIGGINS TAMOXIFEN RESISTANCE DN | 220 | 147 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER LUMINAL B UP | 172 | 109 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER BASAL DN | 701 | 446 | All SZGR 2.0 genes in this pathway |
| CHYLA CBFA2T3 TARGETS UP | 387 | 225 | All SZGR 2.0 genes in this pathway |
| WANG THOC1 TARGETS DN | 20 | 14 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |