Gene Page: TECPR2
Summary ?
| GeneID | 9895 |
| Symbol | TECPR2 |
| Synonyms | KIAA0329|SPG49 |
| Description | tectonin beta-propeller repeat containing 2 |
| Reference | MIM:615000|HGNC:HGNC:19957|Ensembl:ENSG00000196663|HPRD:17184|Vega:OTTHUMG00000171776 |
| Gene type | protein-coding |
| Map location | 14q32.31 |
| Pascal p-value | 0.01 |
| Support | Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| NRSN1 | 0.80 | 0.77 |
| MOCS2 | 0.79 | 0.79 |
| BNIP3 | 0.79 | 0.80 |
| NME5 | 0.78 | 0.82 |
| CA10 | 0.78 | 0.81 |
| TMEM111 | 0.78 | 0.80 |
| SNX3 | 0.78 | 0.79 |
| RWDD2B | 0.77 | 0.79 |
| FBXO9 | 0.76 | 0.81 |
| NKIRAS1 | 0.76 | 0.77 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SH2D2A | -0.51 | -0.58 |
| SMTN | -0.47 | -0.54 |
| SH3BP2 | -0.46 | -0.52 |
| SH2B2 | -0.44 | -0.49 |
| SEMA4B | -0.44 | -0.45 |
| ISLR2 | -0.44 | -0.16 |
| KIAA1949 | -0.43 | -0.36 |
| SF3A2 | -0.43 | -0.34 |
| DACT1 | -0.42 | -0.16 |
| TAX1BP3 | -0.42 | -0.42 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
| DAIRKEE TERT TARGETS DN | 124 | 79 | All SZGR 2.0 genes in this pathway |
| PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
| LOCKWOOD AMPLIFIED IN LUNG CANCER | 214 | 139 | All SZGR 2.0 genes in this pathway |
| POS RESPONSE TO HISTAMINE UP | 13 | 10 | All SZGR 2.0 genes in this pathway |
| BONOME OVARIAN CANCER SURVIVAL OPTIMAL DEBULKING | 246 | 152 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |
| TORCHIA TARGETS OF EWSR1 FLI1 FUSION UP | 271 | 165 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |