Gene Page: ANXA1

Summary
GeneID  301
Symbol  ANXA1
Synonyms  ANX1|LPC1
Description  annexin A1
See related  HGNC:533|MIM:151690|Ensembl:ENSG00000135046|HPRD:01060|
Locus tag  -
Gene type  protein-coding
Map location  9q12-q21.2|9q12-q21.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005102receptor bindingTASNeurotransmitter (GO term level: 4)10882119 
GO:0004859phospholipase inhibitor activityIEA-
GO:0005544calcium-dependent phospholipid bindingIEA-
GO:0005509calcium ion bindingIEA-
GO:0005509calcium ion bindingTAS2967291 
GO:0005515protein bindingIEA-
GO:0005198structural molecule activityIDA10908733 
GO:0019834phospholipase A2 inhibitor activityIEA-
GO:0030674protein binding, bridgingIDA10908733 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007166cell surface receptor linked signal transductionTAS10882119 
GO:0007165signal transductionIEA-
GO:0007049cell cycleIEA-
GO:0006954inflammatory responseTAS10882119 
GO:0006928cell motionTAS10882119 
GO:0006629lipid metabolic processTAS2936963 
GO:0006916anti-apoptosisTAS16130169 
GO:0018149peptide cross-linkingIDA10908733 
GO:0042127regulation of cell proliferationIEA-
GO:0030216keratinocyte differentiationIDA10908733 
GO:0050482arachidonic acid secretionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001533cornified envelopeIDA10908733 
GO:0005634nucleusIEA-
GO:0005737cytoplasmTAS16130169 
GO:0005929ciliumIEA-
GO:0005886plasma membraneIEA-
GO:0016323basolateral plasma membraneIEA-
GO:0042383sarcolemmaIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DLG3KIAA1232 | MRX | MRX90 | NE-Dlg | NEDLG | SAP102discs, large homolog 3 (neuroendocrine-dlg, Drosophila)Affinity Capture-MSBioGRID17353931 
FPR1FMLP | FPRformyl peptide receptor 1-HPRD10882119 
KRT8CARD2 | CK8 | CYK8 | K2C8 | K8 | KOkeratin 8-HPRD,BioGRID9459484 
PPM1BMGC21657 | PP2C-beta-X | PP2CB | PP2CBETA | PPC2BETAXprotein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoformAffinity Capture-MSBioGRID17353931 
S100A11MLN70 | S100CS100 calcium binding protein A11-HPRD,BioGRID8557678 |12645011 
TGM2G-ALPHA-h | GNAH | TG2 | TGCtransglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)-HPRD,BioGRID1670773 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_GCR_PATHWAY 2217All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN 9251All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN 198110All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN 6943All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
BILBAN_B_CLL_LPL_DN 4225All SZGR genes in this pathway
AKL_HTLV1_INFECTION_DN 6841All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN 3722All SZGR genes in this pathway
KERLEY_RESPONSE_TO_CISPLATIN_UP 4430All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_DN 193112All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_LASER_DN 5038All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
RAHMAN_TP53_TARGETS_PHOSPHORYLATED 2118All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_E 8944All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
PETRETTO_CARDIAC_HYPERTROPHY 3426All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN 4429All SZGR genes in this pathway
SANA_TNF_SIGNALING_DN 9057All SZGR genes in this pathway
CHEN_LUNG_CANCER_SURVIVAL 2822All SZGR genes in this pathway
MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_UP 2212All SZGR genes in this pathway
LEE_LIVER_CANCER_DENA_UP 6040All SZGR genes in this pathway
LEE_LIVER_CANCER_E2F1_UP 6235All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP 1713All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN 7748All SZGR genes in this pathway
RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP 3022All SZGR genes in this pathway
TAVOR_CEBPA_TARGETS_UP 4836All SZGR genes in this pathway
IGLESIAS_E2F_TARGETS_UP 151103All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN 408274All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP 314201All SZGR genes in this pathway
NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_DN 2015All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP 7149All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_DN 10170All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
GAJATE_RESPONSE_TO_TRABECTEDIN_UP 6745All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C0 10772All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_UP 222139All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
GEISS_RESPONSE_TO_DSRNA_UP 3829All SZGR genes in this pathway
KEEN_RESPONSE_TO_ROSIGLITAZONE_DN 10668All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
BURTON_ADIPOGENESIS_9 9259All SZGR genes in this pathway
TRACEY_RESISTANCE_TO_IFNA2_DN 3223All SZGR genes in this pathway
VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_DN 1412All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS 9268All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P7 9052All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_FOXP3_TARGETS_STIMULATED_UP 2919All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP 5641All SZGR genes in this pathway
DE_YY1_TARGETS_DN 9264All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP 12568All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_UP 14798All SZGR genes in this pathway
HUANG_DASATINIB_RESISTANCE_UP 8153All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
TOOKER_GEMCITABINE_RESISTANCE_UP 7940All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_D 6844All SZGR genes in this pathway
PARK_APL_PATHOGENESIS_UP 1411All SZGR genes in this pathway
HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN 7561All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP 6242All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_UP 7349All SZGR genes in this pathway
BUDHU_LIVER_CANCER_METASTASIS_UP 107All SZGR genes in this pathway
MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 16280All SZGR genes in this pathway
MIKKELSEN_MEF_LCP_WITH_H3K4ME3 12868All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 172107All SZGR genes in this pathway
HOFFMAN_CLOCK_TARGETS_UP 117All SZGR genes in this pathway
BAE_BRCA1_TARGETS_UP 7547All SZGR genes in this pathway
KAMIKUBO_MYELOID_CEBPA_NETWORK 2819All SZGR genes in this pathway
STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP 4935All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_MESENCHYMAL 216130All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
DALESSIO_TSA_RESPONSE 2916All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 11066All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
NABA_ECM_AFFILIATED 17189All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-38471771Ahsa-miR-384AUUCCUAGAAAUUGUUCAUA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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