ARHGEF12 | DKFZp686O2372 | KIAA0382 | LARG | PRO2792 | Rho guanine nucleotide exchange factor (GEF) 12 | - | HPRD,BioGRID | 11724822 |
CSK | MGC117393 | c-src tyrosine kinase | CSK interacts with IGF-IR. | BIND | 10026153 |
- | HPRD,BioGRID | 10026153 |
DOK5 | C20orf180 | MGC16926 | docking protein 5 | - | HPRD | 12730241 |
EGFR | ERBB | ERBB1 | HER1 | PIG61 | mENA | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | Affinity Capture-Western | BioGRID | 17047074 |
EHD1 | FLJ42622 | FLJ44618 | H-PAST | HPAST1 | PAST | PAST1 | EH-domain containing 1 | - | HPRD,BioGRID | 11423532 |
EHD1 interacts with IGF-1R. | BIND | 11423532 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | Affinity Capture-Western | BioGRID | 16113100 |
GIGYF1 | GYF1 | PERQ1 | GRB10 interacting GYF protein 1 | - | HPRD | 12771153 |
GNAI1 | Gi | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | - | HPRD,BioGRID | 10644671 |
GNAI2 | GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | - | HPRD | 11120746 |
GNB2L1 | Gnb2-rs1 | H12.3 | HLC-7 | PIG21 | RACK1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | IGF-IR interacts with RACK1. | BIND | 11884618 |
- | HPRD,BioGRID | 11884618 |
GRB10 | GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSS | growth factor receptor-bound protein 10 | - | HPRD | 8621530 |8764099
|
Grb10 interacts with IGFIR. | BIND | 9506989 |
Affinity Capture-Western in vitro in vivo Reconstituted Complex Two-hybrid | BioGRID | 8764099 |8776723 |9506989 |12697834
|
IGF1 | IGFI | insulin-like growth factor 1 (somatomedin C) | IGF-I interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between IGF-I from an unspecified species and human IGF-IR. | BIND | 15604363 |
- | HPRD,BioGRID | 1852007 |
IGF1R | CD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216 | insulin-like growth factor 1 receptor | - | HPRD | 12138114 |
IGF2 | C11orf43 | FLJ22066 | FLJ44734 | INSIGF | pp9974 | insulin-like growth factor 2 (somatomedin A) | - | HPRD,BioGRID | 9972281 |
IGFBP3 | BP-53 | IBP3 | insulin-like growth factor binding protein 3 | - | HPRD,BioGRID | 9389554 |
INS | ILPR | IRDN | insulin | Insulin interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between Insulin from an unspecified species and human IGF-IR. | BIND | 15604363 |
- | HPRD | 1851182 |
IRS1 | HIRS-1 | insulin receptor substrate 1 | IGFIR interacts with IRS-1. | BIND | 7541045 |
IRS-1 interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human IGF-IR. | BIND | 10026153 |
- | HPRD,BioGRID | 7559507 |
IRS2 | - | insulin receptor substrate 2 | - | HPRD | 9852124 |
Insulin Receptor Substrate-2 Binds to the Insulin-like Growth Factor Receptor Beta subunit. This interaction is modeled on demonstrated interaction between human IGF-IR and murine IRS-2 | BIND | 8626379 |
ITGB1 | CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLAB | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | beta-1 integrin interacts with IGF-IR. | BIND | 11884618 |
JAK1 | JAK1A | JAK1B | JTK3 | Janus kinase 1 (a protein tyrosine kinase) | Phosphorylated IGF-1R-beta interacts with JAK-1. | BIND | 9492017 |
- | HPRD,BioGRID | 9492017 |
NAMPT | 1110035O14Rik | DKFZp666B131 | MGC117256 | PBEF | PBEF1 | VF | VISFATIN | nicotinamide phosphoribosyltransferase | PBEF interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between PBEF from an unspecified species and human IGF-IR. | BIND | 15604363 |
NEDD4 | KIAA0093 | MGC176705 | NEDD4-1 | RPF1 | neural precursor cell expressed, developmentally down-regulated 4 | - | HPRD,BioGRID | 12697834 |
PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | - | HPRD,BioGRID | 8697095 |
PIK3R2 | P85B | p85 | p85-BETA | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | IGFIR interacts with p85. This interaction was modeled on a demonstrated interaction between rat proteins. | BIND | 7541045 |
PIK3R3 | DKFZp686P05226 | FLJ41892 | p55 | p55-GAMMA | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | - | HPRD,BioGRID | 9415396 |9524259
|
PRKCD | MAY1 | MGC49908 | PKCD | nPKC-delta | protein kinase C, delta | PKC-delta interacts with IGF-IR. | BIND | 11884618 |
PRKD1 | PKC-MU | PKCM | PKD | PRKCM | protein kinase D1 | PKC-mu interacts with IGF-IR. | BIND | 11884618 |
PTK2 | FADK | FAK | FAK1 | pp125FAK | PTK2 protein tyrosine kinase 2 | Affinity Capture-Western | BioGRID | 10082579 |
PTPN1 | PTP1B | protein tyrosine phosphatase, non-receptor type 1 | - | HPRD,BioGRID | 8999839 |
PTPN11 | BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2 | protein tyrosine phosphatase, non-receptor type 11 | - | HPRD,BioGRID | 7642582 |
PXN | FLJ16691 | paxillin | Affinity Capture-Western | BioGRID | 10082579 |
RASA1 | CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAP | RAS p21 protein activator (GTPase activating protein) 1 | - | HPRD,BioGRID | 7642582 |
SHC1 | FLJ26504 | SHC | SHCA | SHC (Src homology 2 domain containing) transforming protein 1 | IGFIR interacts with SHC. | BIND | 7541045 |
- | HPRD,BioGRID | 8776723 |
SNAP29 | CEDNIK | FLJ21051 | SNAP-29 | synaptosomal-associated protein, 29kDa | - | HPRD,BioGRID | 11423532 |
SOCS1 | CIS1 | CISH1 | JAB | SOCS-1 | SSI-1 | SSI1 | TIP3 | suppressor of cytokine signaling 1 | - | HPRD,BioGRID | 9727029 |
Insulin-like Growth Factor-I Receptor interacts with SOCS1 | BIND | 9727029 |
SOCS2 | CIS2 | Cish2 | SOCS-2 | SSI-2 | SSI2 | STATI2 | suppressor of cytokine signaling 2 | Interaction of Human Suppressor of Cytokine Signaling (SOCS)-2 with the Insulin-like Growth Factor-I Receptor | BIND | 9727029 |
- | HPRD,BioGRID | 9727029 |
SOCS3 | ATOD4 | CIS3 | Cish3 | MGC71791 | SOCS-3 | SSI-3 | SSI3 | suppressor of cytokine signaling 3 | Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor I receptor. | BIND | 11071852 |
in vitro in vivo | BioGRID | 11071852 |
VAV3 | FLJ40431 | vav 3 guanine nucleotide exchange factor | - | HPRD,BioGRID | 11094073 |
WISP2 | CCN5 | CT58 | CTGF-L | WNT1 inducible signaling pathway protein 2 | - | HPRD | 10358067 |
YWHAB | GW128 | HS1 | KCIP-1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | - | HPRD,BioGRID | 9581554 |
IGFIR interacts with 14-3-3-beta isoform. This interaction was modelled on a demonstrated interaction between human IGFIR and mouse 14-3-3-beta. | BIND | 9581554 |
YWHAE | 14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | - | HPRD,BioGRID | 9111084 |
IGFIR interacts with 14-3-3-epsilon isoform. This interaction is modeled on a demonstrated interaction between human IGFIR and mouse 14-3-3-epsilon isoform | BIND | 9111084 |
YWHAG | 14-3-3GAMMA | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | Affinity Capture-MS | BioGRID | 17353931 |
YWHAZ | KCIP-1 | MGC111427 | MGC126532 | MGC138156 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | - | HPRD | 9581554 |
IGFIR interacts with 14-3-3-zeta isoform. | BIND | 9581554 |