Gene Page: BCL2

Summary
GeneID  596
Symbol  BCL2
Synonyms  Bcl-2
Description  B-cell CLL/lymphoma 2
See related  HGNC:990|MIM:151430|Ensembl:ENSG00000171791|HPRD:01045|
Locus tag  -
Gene type  protein-coding
Map location  18q21.33|18q21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1729 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZFYVE280.900.87
ZBTB7A0.880.90
CBX70.880.93
PACSIN10.880.89
SYNM0.880.84
CNTNAP10.880.82
MAP1A0.880.81
SIRPA0.870.88
IQSEC30.870.76
COBL0.860.86
Top 10 negatively co-expressed genes
C9orf46-0.67-0.80
EXOSC8-0.65-0.75
DYNLT1-0.64-0.82
BCL7C-0.64-0.73
TUBB2B-0.64-0.63
TRAF4-0.64-0.72
RPS8-0.62-0.80
AC079354.7-0.62-0.68
RPS18-0.62-0.77
KIAA1949-0.62-0.51
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0002020protease bindingIDA10620603 
GO:0042803protein homodimerization activityIDA9111042 
GO:0046982protein heterodimerization activityIPI9111042 
GO:0051434BH3 domain bindingIPI9111042 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0043524negative regulation of neuron apoptosisIEAneuron (GO term level: 9)-
GO:0001836release of cytochrome c from mitochondriaNAS9027314 
GO:0008219cell deathIDA8949945 
GO:0008284positive regulation of cell proliferationIEA-
GO:0008633activation of pro-apoptotic gene productsEXP15231831 
GO:0010039response to iron ionIDA11264898 
GO:0034097response to cytokine stimulusIDA9184696 
GO:0009636response to toxinIDA16307838 
GO:0007565female pregnancyNAS11530860 
GO:0006959humoral immune responseTAS1908951 
GO:0006916anti-apoptosisIDA9027314 |10506221 |10620603 
|11684014 
GO:0009314response to radiationNAS15799693 
GO:0042100B cell proliferationIDA1373874 
GO:0031069hair follicle morphogenesisIEA-
GO:0042493response to drugIDA8949945 
GO:0043496regulation of protein homodimerization activityIDA9111042 
GO:0043497regulation of protein heterodimerization activityIDA9111042 
GO:0051607defense response to virusIDA10620603 
GO:0043473pigmentationIEA-
GO:0032848negative regulation of cellular pH reductionIDA10506221 
GO:0035094response to nicotineIDA12421819 
GO:0046902regulation of mitochondrial membrane permeabilityISS9843949 
GO:0045069regulation of viral genome replicationIEA-
GO:0051881regulation of mitochondrial membrane potentialISS9843949 
GO:0051902negative regulation of mitochondrial depolarizationTAS9027314 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolIEA-
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005634nucleusIEA-
GO:0005737cytoplasmIDA11530860 
GO:0005739mitochondrionIDA9027314 
GO:0005741mitochondrial outer membraneEXP10198631 |11463392 |12624108 
GO:0005741mitochondrial outer membraneIDA9027314 
GO:0005741mitochondrial outer membraneTAS1453000 
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0031965nuclear membraneIDA1502141 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATP2A2ATP2B | DAR | DD | DKFZp686P0211 | FLJ20293 | FLJ38063 | MGC45367 | SERCA2ATPase, Ca++ transporting, cardiac muscle, slow twitch 2-HPRD9788433 
AVENPDCD12apoptosis, caspase activation inhibitorAffinity Capture-Western
Two-hybrid		BioGRID10949025 
BADBBC2 | BCL2L8BCL2-associated agonist of cell deathBcl-2 interacts with Bad.BIND9130713 
-HPRD,BioGRID7834748 
Bad interacts with Bcl-2.BIND15694340 
Bad interacts with Bcl-2.BIND15574335 
BAG1RAP46BCL2-associated athanogene-HPRD,BioGRID9305631 
BAG3BAG-3 | BIS | CAIR-1 | MGC104307BCL2-associated athanogene 3Bcl-2 interacts with BAG-3. This interaction was modelled on a demonstrated interaction between Bcl-2 from an unspecified species and human BAG-3.BIND11527400 
-HPRD11513873 
BAG4BAG-4 | SODDBCL2-associated athanogene 4-HPRD,BioGRID11527400 
Bcl-2 interacts with BAG-4. This interaction was modelled on a demonstrated interaction between Bcl-2 from an unspecified species and human BAG-4.BIND11527400 
BAK1BAK | BAK-LIKE | BCL2L7 | CDN1 | MGC117255 | MGC3887BCL2-antagonist/killer 1-HPRD,BioGRID11728179 
BAXBCL2L4BCL2-associated X protein-HPRD,BioGRID8358790 
Bax interacts with Bcl-2.BIND15574335 
-HPRD8358790|9111042 
Bcl-2 interacts with Bax.BIND9130713 
BBC3JFY1 | PUMABCL2 binding component 3PUMA-beta interacts with Bcl-2.BIND11463392 
-HPRD,BioGRID11463392 
PUMA interacts with Bcl-2.BIND15574335 
PUMA-alpha interacts with Bcl-2.BIND11463392 
Puma interacts with Bcl-2.BIND15694340 
BCAP316C6-AG | BAP31 | CDM | DXS1357EB-cell receptor-associated protein 31-HPRD,BioGRID9334338 
BCL2Bcl-2B-cell CLL/lymphoma 2-HPRD9111042 |15302859 
BCL2L1BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xSBCL2-like 1-HPRD11583631 
Affinity Capture-Western
Protein-peptide		BioGRID12137781 |14980220 
BCL2L10BCL-B | Boo | Diva | MGC129810 | MGC129811BCL2-like 10 (apoptosis facilitator)-HPRD,BioGRID11278245 
BCL2L11BAM | BIM | BIM-alpha6 | BIM-beta6 | BIM-beta7 | BOD | BimEL | BimLBCL2-like 11 (apoptosis facilitator)-HPRD,BioGRID9430630 
Bim interacts with Bcl-2.BIND15694340 
BCL2L14BCLGBCL2-like 14 (apoptosis facilitator)-HPRD11054413 
BCLAF1BTF | KIAA0164 | bK211L9.1BCL2-associated transcription factor 1-HPRD10330179 
BECN1ATG6 | VPS30 | beclin1beclin 1, autophagy related-HPRD,BioGRID9765397 
BFARBAR | RNF47bifunctional apoptosis regulator-HPRD10716992 
BIDFP497 | MGC15319 | MGC42355BH3 interacting domain death agonistBid interacts with Bcl-2.BIND15694340 
Protein-peptideBioGRID15520201 |15694340 
Bid interacts with Bcl-2.BIND15574335 
-HPRD9727491 
BIKBIP1 | BP4 | NBKBCL2-interacting killer (apoptosis-inducing)-HPRD9525867 |12853473|12853473 
Bcl-2 interacts with Bik.BIND9130713 
Bik interacts with Bcl-2.BIND15694340 
-HPRD,BioGRID12853473 
BLKMGC10442B lymphoid tyrosine kinase-HPRD,BioGRID9525867 
BMFFLJ00065Bcl2 modifying factorBmf interacts with Bcl-2. This interaction was modelled on a demonstrated interaction between mouse Bmf and human Bcl-2.BIND15694340 
-HPRD,BioGRID11546872 
BNIP1NIP1 | SEC20 | TRG-8BCL2/adenovirus E1B 19kDa interacting protein 1-HPRD,BioGRID10217402 
BNIP2BNIP-2 | NIP2BCL2/adenovirus E1B 19kDa interacting protein 2-HPRD,BioGRID7954800 |12901880 
BNIP3NIP3BCL2/adenovirus E1B 19kDa interacting protein 3-HPRD,BioGRID10625696 
BNIP3LBNIP3a | NIXBCL2/adenovirus E1B 19kDa interacting protein 3-like-HPRD,BioGRID9973195|10467396 
BNIPLBNIP-S | BNIPL-1 | BNIPL-2 | BNIPL1 | BNIPL2 | PP753BCL2/adenovirus E1B 19kD interacting protein like-HPRD,BioGRID12901880 
BNIPL-2 interacts with Bcl-2.BIND12901880 
CAPN2CANP2 | CANPL2 | CANPml | FLJ39928 | mCANPcalpain 2, (m/II) large subunitBiochemical Activity
Reconstituted Complex		BioGRID12000759 
CASP2CASP-2 | ICH-1L | ICH-1L/1S | ICH1 | NEDD2caspase 2, apoptosis-related cysteine peptidasePhenotypic SuppressionBioGRID11832478 
CASP3CPP32 | CPP32B | SCA-1caspase 3, apoptosis-related cysteine peptidase-HPRD,BioGRID11948397 
CASP8ALPS2B | CAP4 | FLICE | FLJ17672 | MACH | MCH5 | MGC78473caspase 8, apoptosis-related cysteine peptidase-HPRD,BioGRID11406564 
CDC2CDC28A | CDK1 | DKFZp686L20222 | MGC111195cell division cycle 2, G1 to S and G2 to MAffinity Capture-WesternBioGRID11326318 |11774038 
CDK2p33(CDK2)cyclin-dependent kinase 2-HPRD15619620 
CYCSCYC | HCScytochrome c, somatic-HPRD10622714 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1Affinity Capture-WesternBioGRID10198631 
EPHB2CAPB | DRT | EPHT3 | ERK | Hek5 | MGC87492 | PCBC | Tyro5EPH receptor B2Biochemical ActivityBioGRID15225643 
FKBP8FKBP38 | FKBPr38FK506 binding protein 8, 38kDa-HPRD,BioGRID12510191 
HRASC-BAS/HAS | C-H-RAS | C-HA-RAS1 | CTLO | H-RASIDX | HAMSV | HRAS1 | K-RAS | N-RAS | RASH1v-Ha-ras Harvey rat sarcoma viral oncogene homolog-HPRD10490827 
HRKDP5 | HARAKIRIharakiri, BCL2 interacting protein (contains only BH3 domain)-HPRD,BioGRID9130713 |10075695 
Hrk interacts with Bcl-2.BIND9130713 
Hrk interacts with Bcl-2.BIND15694340 
HSPA1AFLJ54303 | FLJ54370 | FLJ54392 | FLJ54408 | FLJ75127 | HSP70-1 | HSP70-1A | HSP70I | HSP72 | HSPA1 | HSPA1Bheat shock 70kDa protein 1A-HPRD,BioGRID10354271 
IRS1HIRS-1insulin receptor substrate 1Affinity Capture-WesternBioGRID10679027 
IRS2-insulin receptor substrate 2Affinity Capture-WesternBioGRID10679027 
ITM2BABRI | BRI | BRI2 | BRICD2B | E25B | E3-16 | FBDintegral membrane protein 2B-HPRD,BioGRID12082633 
ITPR1INSP3R1 | IP3R | IP3R1 | SCA15 | SCA16inositol 1,4,5-triphosphate receptor, type 1Affinity Capture-WesternBioGRID15613488 
KRASC-K-RAS | K-RAS2A | K-RAS2B | K-RAS4A | K-RAS4B | KI-RAS | KRAS1 | KRAS2 | NS3 | RASK2v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog-HPRD10490827 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1-HPRD15225643 
MAPK11P38B | P38BETA2 | PRKM11 | SAPK2 | SAPK2B | p38-2 | p38Betamitogen-activated protein kinase 11-HPRD11495898 
MOAP1MAP-1 | PNMA4modulator of apoptosis 1-HPRD,BioGRID11060313 
MAP-1 interacts with Bcl-2.BIND11060313 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)Affinity Capture-Western
Co-localization		BioGRID15210690 
NR4A1GFRP1 | HMR | MGC9485 | N10 | NAK-1 | NGFIB | NP10 | NUR77 | TR3nuclear receptor subfamily 4, group A, member 1-HPRD,BioGRID14980220 
NRASALPS4 | N-ras | NRAS1neuroblastoma RAS viral (v-ras) oncogene homolog-HPRD10490827 
P53AIP1-p53-regulated apoptosis-inducing protein 1-HPRD,BioGRID12019168 
PARP1ADPRT | ADPRT1 | PARP | PARP-1 | PPOL | pADPRT-1poly (ADP-ribose) polymerase 1-HPRD,BioGRID11790116 
PIN1DOD | UBL5peptidylprolyl cis/trans isomerase, NIMA-interacting 1-HPRD11988841 
Affinity Capture-WesternBioGRID11326318 
PKMYT1DKFZp547K1610 | FLJ20093 | MYT1protein kinase, membrane associated tyrosine/threonine 1-HPRD11326318 
PMAIP1APR | NOXAphorbol-12-myristate-13-acetate-induced protein 1-HPRD,BioGRID10807576 
PPP1CAMGC15877 | MGC1674 | PP-1A | PPP1Aprotein phosphatase 1, catalytic subunit, alpha isoform-HPRD11390485 
PPP2CAPP2Ac | PP2CA | RP-Cprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform-HPRD,BioGRID9852076 
PPP2R4MGC2184 | PP2A | PR53 | PTPAprotein phosphatase 2A activator, regulatory subunit 4Biochemical ActivityBioGRID15225643 
PPP2R5AB56A | MGC131915 | PR61Aprotein phosphatase 2, regulatory subunit B', alpha isoform-HPRD,BioGRID11929874 
PPP3CACALN | CALNA | CALNA1 | CCN1 | CNA1 | PPP2Bprotein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform-HPRD,BioGRID7593193 |9109491 
PSEN1AD3 | FAD | PS1 | S182presenilin 1-HPRD,BioGRID10521466 
RAD9ARAD9RAD9 homolog A (S. pombe)-HPRD,BioGRID10620799 
RAF1CRAF | NS5 | Raf-1 | c-Rafv-raf-1 murine leukemia viral oncogene homolog 1-HPRD,BioGRID8910675 |8929532 
RHEBMGC111559 | RHEB2Ras homolog enriched in brainBcl-2 interacts with Rheb.BIND9130713 
RRAS-related RAS viral (r-ras) oncogene homolog-HPRD,BioGRID8232588 
RTN4ASY | NI220/250 | NOGO | NOGO-A | NOGOC | NSP | NSP-CL | Nbla00271 | Nbla10545 | Nogo-B | Nogo-C | RTN-X | RTN4-A | RTN4-B1 | RTN4-B2 | RTN4-Creticulon 4RTN-XS interacts with Bcl-2.BIND11126360 
-HPRD,BioGRID11126360 
SERPINB8CAP2 | PI8serpin peptidase inhibitor, clade B (ovalbumin), member 8Affinity Capture-WesternBioGRID15231068 
SF1D11S636 | ZFM1 | ZNF162splicing factor 1-HPRD,BioGRID8668206 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomeric-HPRD,BioGRID9389483 
SOD1ALS | ALS1 | IPOA | SOD | homodimersuperoxide dismutase 1, soluble-HPRD,BioGRID15233914 
SPNS1FLJ38358 | HSpin1 | LAT | PP2030 | SPIN1 | SPINL | nrsspinster homolog 1 (Drosophila)-HPRD,BioGRID12815463 
TMBIM6BAXI1 | BI-1 | TEGTtransmembrane BAX inhibitor motif containing 6-HPRD,BioGRID9660918 
TOMM20KIAA0016 | MAS20 | MGC117367 | MOM19 | TOM20translocase of outer mitochondrial membrane 20 homolog (yeast)-HPRD,BioGRID9119086 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD12667443 
TP53BP253BP2 | ASPP2 | BBP | PPP1R13A | p53BP2tumor protein p53 binding protein, 2-HPRD,BioGRID8668206 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_APOPTOSIS 8862All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS 5343All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_COLORECTAL_CANCER 6247All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
BIOCARTA_CHEMICAL_PATHWAY 2215All SZGR genes in this pathway
BIOCARTA_CERAMIDE_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_IL2RB_PATHWAY 3826All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY 1714All SZGR genes in this pathway
BIOCARTA_DEATH_PATHWAY 3324All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY 4638All SZGR genes in this pathway
BIOCARTA_P53_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_BAD_PATHWAY 2623All SZGR genes in this pathway
BIOCARTA_MITOCHONDRIA_PATHWAY 2115All SZGR genes in this pathway
BIOCARTA_HSP27_PATHWAY 1511All SZGR genes in this pathway
BIOCARTA_TEL_PATHWAY 1815All SZGR genes in this pathway
SIG_IL4RECEPTOR_IN_B_LYPHOCYTES 2723All SZGR genes in this pathway
ST_GA13_PATHWAY 3732All SZGR genes in this pathway
SA_FAS_SIGNALING 95All SZGR genes in this pathway
SIG_BCR_SIGNALING_PATHWAY 4638All SZGR genes in this pathway
SA_PROGRAMMED_CELL_DEATH 129All SZGR genes in this pathway
PID_NFAT_3PATHWAY 5447All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_IL2_PI3K_PATHWAY 3427All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY 4837All SZGR genes in this pathway
PID_P53_DOWNSTREAM_PATHWAY 13794All SZGR genes in this pathway
PID_RXR_VDR_PATHWAY 2624All SZGR genes in this pathway
PID_ATF2_PATHWAY 5943All SZGR genes in this pathway
PID_CMYB_PATHWAY 8461All SZGR genes in this pathway
PID_HIV_NEF_PATHWAY 3526All SZGR genes in this pathway
PID_CASPASE_PATHWAY 5239All SZGR genes in this pathway
PID_KIT_PATHWAY 5240All SZGR genes in this pathway
PID_EPO_PATHWAY 3429All SZGR genes in this pathway
PID_IL2_STAT5_PATHWAY 3023All SZGR genes in this pathway
PID_MYC_REPRESS_PATHWAY 6352All SZGR genes in this pathway
REACTOME_APOPTOSIS 14894All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS 1712All SZGR genes in this pathway
REACTOME_INFLAMMASOMES 1712All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 4633All SZGR genes in this pathway
REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS 3021All SZGR genes in this pathway
WINTER_HYPOXIA_DN 5230All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_UP 11272All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_DN 11879All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_DN 4226All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP 2920All SZGR genes in this pathway
MARKS_HDAC_TARGETS_DN 1511All SZGR genes in this pathway
BAKER_HEMATOPOESIS_STAT1_TARGETS 109All SZGR genes in this pathway
BAKER_HEMATOPOIESIS_STAT3_TARGETS 1612All SZGR genes in this pathway
BAKER_HEMATOPOESIS_STAT5_TARGETS 77All SZGR genes in this pathway
GALLUZZI_PERMEABILIZE_MITOCHONDRIA 4331All SZGR genes in this pathway
DUTTA_APOPTOSIS_VIA_NFKB 3325All SZGR genes in this pathway
GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION 2216All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 1812All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_DN 9751All SZGR genes in this pathway
SHANK_TAL1_TARGETS_DN 106All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER 8864All SZGR genes in this pathway
MANTOVANI_NFKB_TARGETS_UP 4333All SZGR genes in this pathway
MANTOVANI_VIRAL_GPCR_SIGNALING_UP 8654All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_A 10063All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
GEORGES_CELL_CYCLE_MIR192_TARGETS 6246All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_3 2823All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
BYSTROEM_CORRELATED_WITH_IL5_DN 6447All SZGR genes in this pathway
GOLDRATH_HOMEOSTATIC_PROLIFERATION 171102All SZGR genes in this pathway
RADAEVA_RESPONSE_TO_IFNA1_UP 5240All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN 5935All SZGR genes in this pathway
TENEDINI_MEGAKARYOCYTE_MARKERS 6648All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
FERRANDO_LYL1_NEIGHBORS 1512All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_DN 169112All SZGR genes in this pathway
YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP 7958All SZGR genes in this pathway
NUMATA_CSF3_SIGNALING_VIA_STAT3 2217All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP 10176All SZGR genes in this pathway
BRUNO_HEMATOPOIESIS 6648All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_DN 2719All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
KIM_GASTRIC_CANCER_CHEMOSENSITIVITY 10364All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
ZHENG_RESPONSE_TO_ARSENITE_UP 1814All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN 4631All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P2 7955All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN 3729All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
CLAUS_PGR_POSITIVE_MENINGIOMA_DN 1210All SZGR genes in this pathway
WONG_MITOCHONDRIA_GENE_MODULE 217122All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_UP 11580All SZGR genes in this pathway
OUYANG_PROSTATE_CANCER_MARKERS 1916All SZGR genes in this pathway
ENGELMANN_CANCER_PROGENITORS_UP 4831All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
MATZUK_EMBRYONIC_GERM_CELL 1916All SZGR genes in this pathway
MATZUK_SPERMATOCYTE 7255All SZGR genes in this pathway
BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 9175All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_UP 4025All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_DN 7450All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_UP 16799All SZGR genes in this pathway
HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN 7561All SZGR genes in this pathway
HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP 4334All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 317177All SZGR genes in this pathway
SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE 8166All SZGR genes in this pathway
ZHAN_LATE_DIFFERENTIATION_GENES_UP 3324All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_UP 7349All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
ONO_FOXP3_TARGETS_DN 4223All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_2 8650All SZGR genes in this pathway
NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN 1811All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_UP 194133All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP 11687All SZGR genes in this pathway
ABDELMOHSEN_ELAVL4_TARGETS 1613All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE 15186All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_2HR_DN 5535All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-143181918251Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-149239824041Ahsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-15/16/195/424/497252925361A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-15326321Ahsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-181175217581Ahsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-1822052111Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-204/2112092161A,m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-20539203926m8hsa-miR-205UCCUUCAUUCCACCGGAGUCUG
miR-217207261Ahsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-217256825741Ahsa-miR-217UACUGCAUCAGGAACUGAUUGGAU
miR-30-5p248724931Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-34/4492032091Ahsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-365171117171Ahsa-miR-365UAAUGCCCCUAAAAAUCCUUAU
miR-3847047101Ahsa-miR-384AUUCCUAGAAAUUGUUCAUA
miR-4485864m8hsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
hsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-493-5p37463752m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-503253025361Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-962052111Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.