Gene Page: FGF18

Summary
GeneID  8817
Symbol  FGF18
Synonyms  FGF-18|ZFGF5
Description  fibroblast growth factor 18
See related  HGNC:3674|MIM:603726|Ensembl:ENSG00000156427|HPRD:04766|
Locus tag  -
Gene type  protein-coding
Map location  5q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MRPS210.900.89
PSMB10.890.91
PSMB30.890.87
SNRPD20.880.87
SCNM10.880.87
ZNF320.870.86
PSMA70.870.90
UFD1L0.870.89
DCTN30.870.87
NME1-NME20.860.89
Top 10 negatively co-expressed genes
AF347015.2-0.57-0.65
AF347015.26-0.56-0.64
AF347015.15-0.56-0.62
SLC6A12-0.56-0.62
AF347015.8-0.55-0.59
EPAS1-0.55-0.61
AF347015.27-0.55-0.60
GATA2-0.54-0.57
MT-CYB-0.54-0.60
MT-ATP8-0.54-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008083growth factor activityTAS9742123 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001525angiogenesisIEA-
GO:0001958endochondral ossificationIEA-
GO:0002063chondrocyte developmentIEA-
GO:0001957intramembranous ossificationIEA-
GO:0007267cell-cell signalingTAS9742123 
GO:0007165signal transductionTAS9742123 
GO:0008284positive regulation of cell proliferationTAS9742123 
GO:0008543fibroblast growth factor receptor signaling pathwayEXP17133345 
GO:0009653anatomical structure morphogenesisTAS9742123 
GO:0030949positive regulation of vascular endothelial growth factor receptor signaling pathwayIEA-
GO:0030324lung developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP1697263 |11294897 |16597617 
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS9742123 
GO:0005730nucleolusIDA11256614 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
PID_FGF_PATHWAY 5537All SZGR genes in this pathway
REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING 3724All SZGR genes in this pathway
REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE 8764All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 12788All SZGR genes in this pathway
REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 1611All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR3_MUTANTS 119All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_MUTANTS 4429All SZGR genes in this pathway
REACTOME_FRS2_MEDIATED_CASCADE 3627All SZGR genes in this pathway
REACTOME_PI_3K_CASCADE 5639All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 10074All SZGR genes in this pathway
REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE 5440All SZGR genes in this pathway
REACTOME_SHC_MEDIATED_CASCADE 2819All SZGR genes in this pathway
REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 10872All SZGR genes in this pathway
REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION 2215All SZGR genes in this pathway
REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION 129All SZGR genes in this pathway
REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION 128All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR 11280All SZGR genes in this pathway
REACTOME_PI3K_CASCADE 7151All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP 182110All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP 15791All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP 194122All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
PEREZ_TP53_AND_TP63_TARGETS 205145All SZGR genes in this pathway
AMUNDSON_GENOTOXIC_SIGNATURE 10568All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_UP 5631All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_8HR_UP 10573All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
MOREIRA_RESPONSE_TO_TSA_DN 1816All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
LU_TUMOR_ANGIOGENESIS_UP 2522All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN 6746All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_POOR_PROGNOSIS 5530All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN 7447All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_UP 5541All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_MIDDLE 9856All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP 259159All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_1HR_UP 3426All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_UP 199143All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
DELACROIX_RAR_TARGETS_UP 4833All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1 467251All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
NABA_SECRETED_FACTORS 344197All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.