Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 80 literature records

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Entrez IDDescription
4118"Data suggest that the epigenetic inactivation of MAL, as a candidate tumor suppressor gene, can contribute to human epithelial cell carcinoma and may be served as a biomarker in HNSCC."
406922"GSTP1 may have an oncogenic function and may be regulated by miR-133alpha, a tumor suppressive miRNA in HNSCC."
8099miR-21 downregulates the tumor suppressor P12 CDK2AP1 and stimulates cell proliferation and invasion.
50943"According to this review, FoxP3 is an important tumor suppressor gene in carcinomas and has putative cancer suppressor gene function in cutaneous melanoma as well."
5909The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma.
23193Loss of the tumor suppression function of Hsp60 or GANAB contribute to aggressive cancers.
3329Loss of the tumor suppression function of Hsp60 or GANAB contribute to aggressive cancers.
4851"identified mutations in FBXW7 and NOTCH in head and neck squamous cell carcinoma; nearly 40% of mutations in NOTCH1 predicted to truncate the gene product, suggesting NOTCH1 may function as tumor suppressor gene rather than oncogene in this tumor type"
8626"By a novel, reversible dynamic mechanism TNF-alpha-induced c-REL/DeltaNp63alpha interactions inactivate tumor suppressor TAp73 function, promoting TNF-alpha resistance & cell survival in cancers with mtTP53."
4771"Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor."
5728Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.
406922MSN was regulated by tumor suppressive miR-133a and contributed to HNSCC oncogenesis.
406922this analysis data of novel tumor-suppressive miR-133a-mediated cancer pathways could provide new insights into the potential mechanisms of HNSCC oncogenesis.
3169These results suggest that FOXA1 functions as a tumor suppressor through modulation of proliferation and migration of endometrial cancer cells.
2779"Three candidate tumor-suppressor genes, SEMA3B, AXUD1 and GNAT1 may be involved in oral squamous cell carcinoma."
383The tumor suppressive function of arginase-I in both infiltrating and circulating myeloid-derived suppressor cells is a downstream target of activated STAT3.
6774The tumor suppressive function of arginase-I in both infiltrating and circulating myeloid-derived suppressor cells is a downstream target of activated STAT3.
4486"the function of RON in tumors may be multidimensional, not just as a tumor suppressor or oncogene."
5241"these findings support a role for PR as a tumor suppressor in ovarian cancer cells, which exhibits inhibitory effects by inducing FOXO1-dependent cellular senescence."
1496CTNNA2 and CTNNA3 are tumor suppressor genes frequently mutated in laryngeal carcinomas.
29119CTNNA2 and CTNNA3 are tumor suppressor genes frequently mutated in laryngeal carcinomas.
57758Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition.
27022"Results indicate that FOXD3 exhibits tumor suppressive activity that affects the growth, aggressiveness and angiogenesis of NB through transcriptional regulation of NDRG1."
7053"TGM3, a candidate tumor suppressor, contributes to the carcinogenesis and development of human head and neck cancer."
27022Our results indicate FOXD3 exhibits tumor suppressive activity and may be useful for breast therapy.
574507Data shows that loss of tumor-suppressive miR-504 enhanced of hypopharyngeal squamous cell carcinoma proliferation through targeting CDK6.
1843"Together, our results clearly establish the role of Dusp1 as a tumor suppressor gene that regulates cancer-associated inflammation."
3621Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1).
3621Localization of the candidate tumor suppressor gene ING1 to human chromosome 13q34.
326343"Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells."


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