Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
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Found 139 literature records
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Entrez ID
Description
5245
"Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function."
5933
"Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function."
1026
Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.
5925
Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.
5925
The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.
5925
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
5933
The p107 tumor suppressor induces stable E2F DNA binding to repress target promoters.
5925
Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
7799
"Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily."
6595
Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.
5925
these studies couple the activity of the retinoblastoma and mismatch repair tumor suppressor pathways through the degradation of cyclin D1 and dual attenuation of CDK2 activity
1029
Human tumor suppressor ARF impedes S-phase progression independent of p53.
7157
Human tumor suppressor ARF impedes S-phase progression independent of p53.
7490
The Wilms' tumor suppressor Wt1 is associated with the differentiation of retinoblastoma cells.
5925
Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication.
5925
Retinoblastoma tumor suppressor and genome stability.
5925
Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5933
Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5934
Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5925
Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor.
6595
This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
6597
This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
7161
p73 isoforms affect the retinoblastoma protein (RB) tumor suppressor pathway independent of p53
5925
Senescence-associated heterochromatic foci formation coincides with the recruitment of heterochromatin proteins and the retinoblastoma (Rb) tumor suppressor to E2F-responsive promoters and is associated with the stable repression of E2F target genes.
11186
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
5925
These results indicate that PAI-2 may enhance Rb's tumor suppressor activity and suggest a potential therapeutic role for PAI-2 against HPV-transformed lesions.
1871
"E2F3 loss leads to an increase in the rate of tumor initiation. Finally, analysis of Rb(+/-); E2f3(+/-) mice shows that this tumor-suppressive function of E2F3 is dose dependent."
7490
WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.
5925
"How the other half lives, the amino-terminal domain of the retinoblastoma tumor suppressor protein."
5925
Effect of retinoblastoma tumor suppressor gene expression on chemosensitivity of human osteosarcoma cell lines.
5925
kinetic framework of RB tumor suppressor action in transcriptional repression and cell cycle regulation
11186
Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.
2077
ERF is a ubiquitously expressed ets domain transcriptional repressor with tumor suppressor activity that is regulated by the Ras/Erk signaling pathway.
5925
Data show that geminin is regulated transcriptionally by the retinoblastoma tumor suppressor (RB)/E2F pathway.
5925
Data demonstrate that Plk1 (Polo-like kinase 1) is a target of the retinoblastoma tumor suppressor (RB) pathway.
5934
"pRb2/p130 overexpression is able to arrest cell growth in ovarian carcinoma cells, suggesting the putative role of pRb2/p130 as a tumor suppressor in this malignancy."
6598
The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.
1316
Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.
5925
Distinct mechanisms for repression of RNA polymerase III transcription by the retinoblastoma tumor suppressor protein.
7157
"p28 expression resulted in an accumulation of hypophosphorylated retinoblastoma protein (pRb), tumor suppressor p53, and cyclin-dependent kinase (Cdk) inhibitor p21(Cip1)."
5915
(RAR)beta functions as a tumor suppressor gene in various contexts where its absence is associated with tumorigenicity and its presence causes cell cycle arrest.
1009
"A 2.62 Mbp minimal region of genomic loss of chromosome 16q22 was found in retinoblastoma which contains a hotspot CDH11, implicating CDH11as a potential tumor suppressor gene in retinoblastoma."
5925
The Rb tumor suppressor is required for stress erythropoiesis.
5925
"LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription."
8994
"LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription."
5933
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.
5934
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.
5925
Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor.
5925
The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes.
9077
E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.
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