Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 139 literature records

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Entrez IDDescription
5245"Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function."
5933"Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function."
1026Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.
5925Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.
5925The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.
5925RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
5933The p107 tumor suppressor induces stable E2F DNA binding to repress target promoters.
5925Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.
7799"Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily."
6595Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.
5925these studies couple the activity of the retinoblastoma and mismatch repair tumor suppressor pathways through the degradation of cyclin D1 and dual attenuation of CDK2 activity
1029Human tumor suppressor ARF impedes S-phase progression independent of p53.
7157Human tumor suppressor ARF impedes S-phase progression independent of p53.
7490The Wilms' tumor suppressor Wt1 is associated with the differentiation of retinoblastoma cells.
5925Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication.
5925Retinoblastoma tumor suppressor and genome stability.
5925Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5933Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5934Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity.
5925Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor.
6595This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
6597This report provides supportive evidence that BRG1 and BRM act as tumor suppressor proteins and implicates a role for their loss in the development of non-small cell lung cancers.
7161p73 isoforms affect the retinoblastoma protein (RB) tumor suppressor pathway independent of p53
5925Senescence-associated heterochromatic foci formation coincides with the recruitment of heterochromatin proteins and the retinoblastoma (Rb) tumor suppressor to E2F-responsive promoters and is associated with the stable repression of E2F target genes.
11186The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
5925These results indicate that PAI-2 may enhance Rb's tumor suppressor activity and suggest a potential therapeutic role for PAI-2 against HPV-transformed lesions.
1871"E2F3 loss leads to an increase in the rate of tumor initiation. Finally, analysis of Rb(+/-); E2f3(+/-) mice shows that this tumor-suppressive function of E2F3 is dose dependent."
7490WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.
5925"How the other half lives, the amino-terminal domain of the retinoblastoma tumor suppressor protein."
5925Effect of retinoblastoma tumor suppressor gene expression on chemosensitivity of human osteosarcoma cell lines.
5925kinetic framework of RB tumor suppressor action in transcriptional repression and cell cycle regulation
11186Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.
2077ERF is a ubiquitously expressed ets domain transcriptional repressor with tumor suppressor activity that is regulated by the Ras/Erk signaling pathway.
5925Data show that geminin is regulated transcriptionally by the retinoblastoma tumor suppressor (RB)/E2F pathway.
5925Data demonstrate that Plk1 (Polo-like kinase 1) is a target of the retinoblastoma tumor suppressor (RB) pathway.
5934"pRb2/p130 overexpression is able to arrest cell growth in ovarian carcinoma cells, suggesting the putative role of pRb2/p130 as a tumor suppressor in this malignancy."
6598The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.
1316Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.
5925Distinct mechanisms for repression of RNA polymerase III transcription by the retinoblastoma tumor suppressor protein.
7157"p28 expression resulted in an accumulation of hypophosphorylated retinoblastoma protein (pRb), tumor suppressor p53, and cyclin-dependent kinase (Cdk) inhibitor p21(Cip1)."
5915(RAR)beta functions as a tumor suppressor gene in various contexts where its absence is associated with tumorigenicity and its presence causes cell cycle arrest.
1009"A 2.62 Mbp minimal region of genomic loss of chromosome 16q22 was found in retinoblastoma which contains a hotspot CDH11, implicating CDH11as a potential tumor suppressor gene in retinoblastoma."
5925The Rb tumor suppressor is required for stress erythropoiesis.
5925"LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription."
8994"LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription."
5933Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.
5934Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130.
5925Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor.
5925The retinoblastoma tumor suppressor protein is required for efficient processing and repair of trapped topoisomerase II-DNA-cleavable complexes.
9077E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.


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