Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB01054 |
| Drug Name | Nitrendipine |
| Target ID | BE0008715 |
| UniProt ID | O00555 |
| Regulation Type | inhibitor |
| PubMed IDs | 11119684; 32766273 |
| Citations | Mize RR, Lo F: Nitric oxide, impulse activity, and neurotrophins in visual system development(1). Brain Res. 2000 Dec 15;886(1-2):15-32. doi: 10.1016/s0006-8993(00)02750-5.@@Goswami C, Dezaki K, Wang L, Inui A, Seino Y, Yada T: Ninjin'yoeito Targets Distinct Ca(2+) Channels to Activate Ghrelin-Responsive vs. Unresponsive NPY Neurons in the Arcuate Nucleus. Front Nutr. 2020 Jul 17;7:104. doi: 10.3389/fnut.2020.00104. eCollection 2020. |
| Groups | Approved; Investigational |
| Direct Classification | Dihydropyridinecarboxylic acids and derivatives |
| SMILES | CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC |
| Pathways | Nitrendipine Action Pathway |
| PharmGKB | PA146096020 |
| ChEMBL | CHEMBL475534 |
