Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB13961 |
| Drug Name | Fish oil |
| Target ID | BE0009739 |
| UniProt ID | O00305 |
| Regulation Type | inhibitor |
| PubMed IDs | 22393325; 9760040; 19419761; 22973228; 28220076 |
| Citations | Visioli F, Giordano E, Nicod NM, Davalos A: Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. Front Physiol. 2012 Feb 29;3:42. doi: 10.3389/fphys.2012.00042. eCollection 2012.@@Hazama H, Nakajima T, Asano M, Iwasawa K, Morita T, Igarashi K, Nagata T, Horiuchi T, Suzuki J, Soma M, Okuda Y: Omega-3 polyunsaturated fatty acids--modulation of voltage-dependent L-type Ca2+ current in guinea-pig tracheal smooth muscle cells. Eur J Pharmacol. 1998 Aug 21;355(2-3):257-66. doi: 10.1016/s0014-2999(98)00484-1.@@Roberts-Crowley ML, Mitra-Ganguli T, Liu L, Rittenhouse AR: Regulation of voltage-gated Ca2+ channels by lipids. Cell Calcium. 2009 Jun;45(6):589-601. doi: 10.1016/j.ceca.2009.03.015. Epub 2009 May 6.@@Moreno C, Macias A, Prieto A, De La Cruz A, Valenzuela C: Polyunsaturated Fatty acids modify the gating of kv channels. Front Pharmacol. 2012 Sep 10;3:163. doi: 10.3389/fphar.2012.00163. eCollection 2012.@@Elinder F, Liin SI: Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels. Front Physiol. 2017 Feb 6;8:43. doi: 10.3389/fphys.2017.00043. eCollection 2017. |
| Groups | Approved; Nutraceutical |
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