Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB11633 |
| Drug Name | Isavuconazole |
| Target ID | BE0000430 |
| UniProt ID | Q13936 |
| Regulation Type | inhibitor |
| PubMed IDs | 28074556 |
| Citations | Keirns J, Desai A, Kowalski D, Lademacher C, Mujais S, Parker B, Schneidkraut MJ, Townsend R, Wojtkowski T, Yamazaki T, Yen M, Kowey PR: QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization. Clin Pharmacol Ther. 2017 Jun;101(6):782-790. doi: 10.1002/cpt.620. Epub 2017 Feb 13. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylpropanes |
| SMILES | C[C@@H](C1=NC(=CS1)C1=CC=C(C=C1)C#N)[C@](O)(CN1C=NC=N1)C1=C(F)C=CC(F)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL409153 |
