Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1C |
|---|---|
| DrugBank ID | DB00308 |
| Drug Name | Ibutilide |
| Target ID | BE0000430 |
| UniProt ID | Q13936 |
| Regulation Type | activator |
| PubMed IDs | 15926871; 9257085; 11752352 |
| Citations | Doggrell SA, Hancox JC: Ibutilide--recent molecular insights and accumulating evidence for use in atrial flutter and fibrillation. Expert Opin Investig Drugs. 2005 May;14(5):655-69.@@Foster RH, Wilde MI, Markham A: Ibutilide. A review of its pharmacological properties and clinical potential in the acute management of atrial flutter and fibrillation. Drugs. 1997 Aug;54(2):312-30.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Phenylbutylamines |
| SMILES | CCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1 |
| Pathways | Ibutilide Action Pathway |
| PharmGKB | PA449958 |
| ChEMBL | CHEMBL533 |
