| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20056727 | HPV | ENSG00000144852.20 | protein_coding | NR1I2 | No | No | 8856 | O75469 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | NR1I2 |
|---|---|
| DrugBank ID | DB01174 |
| Drug Name | Phenobarbital |
| Target ID | BE0000956 |
| UniProt ID | O75469 |
| Regulation Type | activator |
| PubMed IDs | 14977870; 15039302 |
| Citations | Faucette SR, Wang H, Hamilton GA, Jolley SL, Gilbert D, Lindley C, Yan B, Negishi M, LeCluyse EL: Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. Drug Metab Dispos. 2004 Mar;32(3):348-58.@@Kobayashi K, Yamagami S, Higuchi T, Hosokawa M, Chiba K: Key structural features of ligands for activation of human pregnane X receptor. Drug Metab Dispos. 2004 Apr;32(4):468-72. |
| Groups | Approved; Investigational |
| Direct Classification | Barbituric acid derivatives |
| SMILES | CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA450911 |
| ChEMBL | CHEMBL40 |
