| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20056727 | HPV | ENSG00000144852.20 | protein_coding | NR1I2 | No | No | 8856 | O75469 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NR1I2 |
|---|---|
| DrugBank ID | DB08864 |
| Drug Name | Rilpivirine |
| Target ID | BE0000956 |
| UniProt ID | O75469 |
| Regulation Type | agonist |
| PubMed IDs | 23583259 |
| Citations | Sharma D, Lau AJ, Sherman MA, Chang TK: Agonism of human pregnane X receptor by rilpivirine and etravirine: comparison with first generation non-nucleoside reverse transcriptase inhibitors. Biochem Pharmacol. 2013 Jun 1;85(11):1700-11. doi: 10.1016/j.bcp.2013.04.002. Epub 2013 Apr 9. |
| Groups | Approved |
| Direct Classification | Benzonitriles |
| SMILES | CC1=CC(C=CC#N)=CC(C)=C1NC1=CC=NC(NC2=CC=C(C=C2)C#N)=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL175691 |