DegronMD

Class: SCF_FBXO31

Description:

FBX031 motif. FBXO31 interacts with the Skp1-Cul1-Roc1 (SCF) complex forming a functional SCF-FBXO31 E3 ubiquitin ligase. It binds the substrate with a motif of PTDV[A-Z]{2}[VI][A-Z]{1}[IL]$.

Uniprot ID	Degron Hit	Degron Class	Location	E3 ligase	Source protein	Detail
P24385	PTDVRDVDI	SCF_FBXO31	287:295	FBXO31	G1/S-specific cyclin-D1	Detail..
P30279	PTDVRDIDL	SCF_FBXO31	281:289	FBXO31	G1/S-specific cyclin-D2	Detail..
P30281	PTDVTAIHL	SCF_FBXO31	284:292	FBXO31	G1/S-specific cyclin-D3	Detail..

DegronMD: protein-targeted degradation, mutation and drug response to degrons

Class: SCF_FBXO31

Description:

All proteins holding degrons of class SCF_FBXO31