DegronMD

Uniprot ID: Q96M43

Source protein: Neuroblastoma breakpoint family member 4

Source gene: NBPF4

Class: DEG_SPOP_SBC_1

Location: 454:458

E3 ligase: SPOP

DEGRON score: 0.9948

ASA_SCORE: 70.34

COIL: 0.8088

CONS_SCORE: 0.7209

DSS_SCORE: 0.4173

HELIX: 0.119

FCONS_SCORE: 1.286

RIG_SCORE: 0.7184

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96M43	Neuroblastoma breakpoint family member 4	DEG_SPOP_SBC_1	454:458	PYSST	SPOP	0.9948	More...
Q5VWK0	Neuroblastoma breakpoint family member 6	DEG_SPOP_SBC_1	454:458	PYSST	SPOP	0.9861	More...
Q5VV67	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1	DEG_SPOP_SBC_1	972:976	PYSST	SPOP	0.9181	More...
Q9BSJ6	Protein PIMREG	DEG_SPOP_SBC_1	186:190	PYSST	SPOP	0.9992	More...
A1L4H1	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	DEG_SPOP_SBC_1	1131:1135	PYSST	SPOP	0.9205	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons