DegronMD - A1L4H1(SSC5D)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P1074L	TCGA-2W-A8YY	CESC	TCGA	LSTPDSS	DEG_SCF_FBW7_1	1071:1077	Mutation altering degron motif	0.7582
p.P1074L	DO223732	CESC	ICGC	LSTPDSS	DEG_SCF_FBW7_1	1071:1077	Mutation altering degron motif	0.7582
p.S1077R	TCGA-5P-A9KA	KIRP	TCGA	LSTPDSS	DEG_SCF_FBW7_1	1071:1077	Mutation altering degron motif	0.7427
p.S1077R	DO223953	KIRP	ICGC	LSTPDSS	DEG_SCF_FBW7_1	1071:1077	Mutation altering degron motif	0.7427
p.S1148N	TCGA-A5-A0G1	UCEC	TCGA	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.25
p.S1148N	DO42472	UCEC	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.25
p.S1340P	TCGA-AA-3510	COAD	TCGA	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.0833
p.S1340P	DO7783	COAD	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.0833
p.S1340P	ACH-001518	Endometrial/Uterine Cancer	CCLE	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.0833
p.H1186Y	TCGA-AC-A23H	BRCA	TCGA	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.H1186Y	DO2401	BRCA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.R913W	TCGA-AD-6548	COAD	TCGA	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.2778
p.R913W	TCGA-AD-6895	COAD	TCGA	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.2778
p.R913W	DO8938	COAD	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.2778
p.R913W	DO9586	COAD	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.2778
p.R913W	DO233791	GACA	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.2778
p.A1081T	TCGA-AJ-A8CT	UCEC	TCGA	PALTPEPS	DEG_SCF_FBW7_1	1080:1087	Mutation altering degron motif	0.6028
p.A1081T	DO52399	UCEC	ICGC	PALTPEPS	DEG_SCF_FBW7_1	1080:1087	Mutation altering degron motif	0.6028
p.P1241S	TCGA-AP-A1DK	UCEC	TCGA	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.6752
p.P1241S	DO42033	UCEC	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.6752
p.A1546T	TCGA-AX-A1CF	UCEC	TCGA	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.25
p.A1546T	TCGA-AX-A1CF	UCEC	TCGA	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.0556
p.A1546T	DO43795	UCEC	ICGC	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.25
p.A1546T	DO43795	UCEC	ICGC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.0556
p.A1160D	TCGA-AZ-6601	COAD	TCGA	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.2778
p.A1160D	DO8119	COAD	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.2778
p.T1279M	TCGA-CM-5348	COAD	TCGA	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation rewiring degron network	0.0556
p.T1279M	DO9514	COAD	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation rewiring degron network	0.0556
p.T1279M	DO222703	COCA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation rewiring degron network	0.0556
p.A1541V	TCGA-D5-6928	COAD	TCGA	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.1111
p.A1541V	DO7776	COAD	ICGC	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.1111
p.K1411E	TCGA-EY-A1GD	UCEC	TCGA	PNLTPPPT	DEG_SCF_FBW7_1	1418:1425	Mutation substituting flanking lysine	0.25
p.K1411E	DO42129	UCEC	ICGC	PNLTPPPT	DEG_SCF_FBW7_1	1418:1425	Mutation substituting flanking lysine	0.25
p.E1540D	TCGA-FI-A2D6	UCEC	TCGA	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.0833
p.E1540D	DO43867	UCEC	ICGC	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.0833
p.P1293S	TCGA-G3-A25W	LIHC	TCGA	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6752
p.P1293S	DO22970	LIHC	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6752
p.P1095L	TCGA-XR-A8TD	LIHC	TCGA	PALTPEPS	DEG_SCF_FBW7_1	1080:1087	Mutation rewiring degron network	0.1111
p.P1095L	TCGA-XR-A8TD	LIHC	TCGA	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation rewiring degron network	0.2778
p.P1095L	DO223921	LIHC	ICGC	PALTPEPS	DEG_SCF_FBW7_1	1080:1087	Mutation rewiring degron network	0.1111
p.P1095L	DO223921	LIHC	ICGC	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation rewiring degron network	0.2778
p.R924C	DO225186	BRCA	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.1944
p.G1460E	DO10172	COAD	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.6087
p.P1456S	DO230334	COCA	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.P1456S	DO229016	COCA	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.P1456S	DO229003	COCA	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.P1456S	DO52365	LUSC	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.P1456S	DO231018	LUSC	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.H1186Q	DO222790	COCA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.H1186Q	DO229005	COCA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.H1186Q	DO228947	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.H1186Q	DO229047	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.2222
p.R1567I	DO222884	COCA	ICGC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.1389
p.H1294Y	DO229005	COCA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6118
p.H1294Y	DO228941	LICA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6118
p.H1294Y	DO228947	LICA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6118
p.H1294Y	DO229047	LICA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6118
p.H1294Y	DO229006	LICA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.6118
p.T1183M	DO229005	COCA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.T1183M	DO228941	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.T1183M	DO228947	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.T1183M	DO229047	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.T1182S	DO229005	COCA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation altering degron motif	0.6005
p.T1182S	DO228941	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation altering degron motif	0.6005
p.T1182S	DO228947	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation altering degron motif	0.6005
p.T1182S	DO229047	LICA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation altering degron motif	0.6005
p.R924H	DO50321	ESAD	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.1944
p.R924H	ACH-000700	Lung Cancer	CCLE	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.1944
p.T1089S	DO233737	GACA	ICGC	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation altering degron motif	0.7116
p.Y1312D	DO51017	LAML	ICGC	PTMTPDPT	DEG_SCF_FBW7_1	1301:1308	Mutation rewiring degron network	0.2222
p.Y1312D	DO51017	LAML	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.T1152P	DO228912	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation altering degron motif	0.5919
p.H1246Q	DO228947	LICA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.647
p.H1246Q	DO229259	THCA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.647
p.D1318H	DO228957	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation altering degron motif	0.6577
p.D1318H	DO229028	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation altering degron motif	0.6577
p.D1318H	DO229008	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation altering degron motif	0.6577
p.Y1312H	DO229028	LICA	ICGC	PTMTPDPT	DEG_SCF_FBW7_1	1301:1308	Mutation rewiring degron network	0.2222
p.Y1312H	DO229028	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.Y1312H	DO229031	LICA	ICGC	PTMTPDPT	DEG_SCF_FBW7_1	1301:1308	Mutation rewiring degron network	0.2222
p.Y1312H	DO229031	LICA	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.A1556S	DO229026	LICA	ICGC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation altering degron motif	0.7588
p.V1542L	DO229041	LICA	ICGC	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.1389
p.R914L	DO229045	LICA	ICGC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.3056
p.V1335F	DO229006	LICA	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.2222
p.P1325T	DO50940	LICA	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation altering degron motif	0.7031
p.P1325T	DO231760	LINC	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation altering degron motif	0.7031
p.Y1139H	DO23610	LUAD	ICGC	LDTTPYSS	DEG_SCF_FBW7_1	1127:1134	Mutation rewiring degron network	0.1944
p.Y1139H	DO23610	LUAD	ICGC	PYSST	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.2222
p.P1305A	DO228231	MALY	ICGC	PTMTPDPT	DEG_SCF_FBW7_1	1301:1308	Mutation altering degron motif	0.7503
p.P1247L	DO220891	MELA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.6471
p.P1328L	DO222887	MELA	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation altering degron motif	0.7582
p.P1328L	DO41199	UCEC	ICGC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation altering degron motif	0.7582
p.P1456L	DO232064	ORCA	ICGC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.25
p.I1190M	DO46733	PACA	ICGC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.1111
p.H1150P	DO48573	PAEN	ICGC	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.3056
p.S1236P	DO229470	SKCA	ICGC	PTTTPHST	DEG_SCF_FBW7_1	1230:1237	Mutation altering degron motif	0.5641
p.S1236P	DO229232	THCA	ICGC	PTTTPHST	DEG_SCF_FBW7_1	1230:1237	Mutation altering degron motif	0.5641
p.E1564K	DO37896	SKCM	ICGC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.2222
p.D1306H	DO229268	THCA	ICGC	PTMTPDPT	DEG_SCF_FBW7_1	1301:1308	Mutation altering degron motif	0.6577
p.T1290P	DO229216	THCA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1289:1296	Mutation altering degron motif	0.5919
p.T1254P	DO229211	THCA	ICGC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation rewiring degron network	0.1667
p.C1473Y	SIDM02021	Esophageal Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1389
p.E1565K	SIDM00545	Melanoma	GDSC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.1944
p.E1565K	ACH-000987	Skin Cancer	CCLE	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.1944
p.E1565K	Mewo	skin	COSMIC	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.1944
p.G1468C	SIDM00680	Colorectal Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.2778
p.G1468C	ACH-000957	Colon/Colorectal Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.2778
p.G1468C	LS-180	large intestine	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.2778
p.S1140F	SIDM01002	Breast Carcinoma	GDSC	LDTTPYSS	DEG_SCF_FBW7_1	1127:1134	Mutation rewiring degron network	0.1667
p.S1140F	SIDM01002	Breast Carcinoma	GDSC	PYSST	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.S1140F	ACH-000117	Breast Cancer	CCLE	LDTTPYSS	DEG_SCF_FBW7_1	1127:1134	Mutation rewiring degron network	0.1667
p.S1140F	ACH-000117	Breast Cancer	CCLE	PYSST	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.S1140F	EFM-192A	breast	COSMIC	LDTTPYSS	DEG_SCF_FBW7_1	1127:1134	Mutation rewiring degron network	0.1667
p.S1140F	EFM-192A	breast	COSMIC	PYSST	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.D1450N	SIDM00630	Breast Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.0833
p.D1450N	ACH-000876	Breast Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.0833
p.D1450N	MDA-MB-415	breast	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.0833
p.F1175Y	SIDM00286	Neuroblastoma	GDSC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.F1175Y	SIDM00832	Colorectal Carcinoma	GDSC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.F1175Y	SIDM01099	Neuroblastoma	GDSC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.F1175Y	SIDM00734	Non-Small Cell Lung Carcinoma	GDSC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.F1175Y	SIDM01680	Non-Cancerous	GDSC	PTTPHPT	DEG_SCF_FBW7_1	1176:1182	Mutation rewiring degron network	0.3056
p.I1336V	SIDM00745	Non-Small Cell Lung Carcinoma	GDSC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.1944
p.I1336V	ACH-000035	Lung Cancer	CCLE	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.1944
p.I1336V	NCI-H1650	lung	COSMIC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.1944
p.S1103F	SIDM00713	Mesothelioma	GDSC	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation rewiring degron network	0.0556
p.S1103F	ACH-000153	Lung Cancer	CCLE	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation rewiring degron network	0.0556
p.S1103F	NCI-H2052	pleura	COSMIC	PTPLPT	DEG_SCF_FBW7_1	1088:1093	Mutation rewiring degron network	0.0556
p.P1453T	SIDM00767	Small Cell Lung Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1667
p.P1453T	ACH-001136	Lung Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1667
p.P1453T	NCI-H187	lung	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1667
p.P1086L	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PALTPEPS	DEG_SCF_FBW7_1	1080:1087	Mutation altering degron motif	0.6471
p.R914C	SIDM00218	Thyroid Gland Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.3056
p.R914C	RO82-W-1	thyroid	COSMIC	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.3056
p.T1243M	SIDM00068	Colorectal Carcinoma	GDSC	PTTTPHPT	DEG_SCF_FBW7_1	1241:1248	Mutation altering degron motif	0.6312
p.T1321M	SIDM00431	T-Lymphoblastic Leukemia	GDSC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.T1321M	SIDM00431	T-Lymphoblastic Leukemia	GDSC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.2222
p.T1321M	ACH-000918	Leukemia	CCLE	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.T1321M	ACH-000918	Leukemia	CCLE	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.2222
p.T1321M	MOLT-16	haematopoietic and lymphoid tissue	COSMIC	PTTTPDPT	DEG_SCF_FBW7_1	1313:1320	Mutation rewiring degron network	0.3056
p.T1321M	MOLT-16	haematopoietic and lymphoid tissue	COSMIC	PTTPDPS	DEG_SCF_FBW7_1	1325:1331	Mutation rewiring degron network	0.2222
p.S1466N	SIDM00534	Colorectal Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.7069
p.S1466N	ACH-000986	Colon/Colorectal Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.7069
p.S1466N	HT-115	large intestine	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.7069
p.P1461S	SIDM00220	Ovarian Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.5641
p.P1461S	ACH-000962	Ovarian Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.5641
p.P1461S	ACH-001145	Ovarian Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.5641
p.P1461S	OC-314	ovary	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation altering degron motif	0.5641
p.C1473R	SIDM00839	Colorectal Carcinoma	GDSC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1389
p.C1473R	ACH-000950	Colon/Colorectal Cancer	CCLE	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1389
p.C1473R	LoVo	large intestine	COSMIC	LGPTPGQS	DEG_SCF_FBW7_1	1459:1466	Mutation rewiring degron network	0.1389
p.P1562T	ACH-000844	Lung Cancer	CCLE	AWTTS	DEG_SPOP_SBC_1	1549:1553	Mutation rewiring degron network	0.0833
p.P1562T	ACH-000844	Lung Cancer	CCLE	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.2778
p.R1570K	ACH-000851	Lung Cancer	CCLE	APTTT	DEG_SPOP_SBC_1	1556:1560	Mutation rewiring degron network	0.0556
p.D927N	ACH-001524	Skin Cancer	CCLE	PGSSS	DEG_SPOP_SBC_1	915:919	Mutation rewiring degron network	0.1111
p.S1140Y	ACH-001846	Bile Duct Cancer	CCLE	LDTTPYSS	DEG_SCF_FBW7_1	1127:1134	Mutation rewiring degron network	0.1667
p.S1140Y	ACH-001846	Bile Duct Cancer	CCLE	PYSST	DEG_SPOP_SBC_1	1131:1135	Mutation rewiring degron network	0.1944
p.I1164T	ARH-77	haematopoietic and lymphoid tissue	COSMIC	PTTTPDPT	DEG_SCF_FBW7_1	1151:1158	Mutation rewiring degron network	0.1667

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SSC5D

UniProt ID: A1L4H1

Entrez ID: 284297

Protein name: Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Soluble scavenger protein with 5 SRCR domains) (SSc5D)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SSC5D in