DegronMD

Uniprot ID: Q5H9F3

Source protein: BCL-6 corepressor-like protein 1

Source gene: BCORL1

Class: DEG_SPOP_SBC_1

Location: 650:654

E3 ligase: SPOP

DEGRON score: 0.9938

ASA_SCORE: 88.14

COIL: 0.9132

CONS_SCORE: 0.6717

DSS_SCORE: 0.5144

HELIX: 0.0552

FCONS_SCORE: 1.0488

RIG_SCORE: 0.7377

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S663C	TCGA-05-4244	LUAD	TCGA	VHTSS	DEG_SPOP_SBC_1	0.5278
p.S663C	DO23553	LUAD	ICGC	VHTSS	DEG_SPOP_SBC_1	0.5278
p.S659Y	TCGA-FU-A40J	CESC	TCGA	VHTSS	DEG_SPOP_SBC_1	0.6389
p.S659Y	DO44314	CESC	ICGC	VHTSS	DEG_SPOP_SBC_1	0.6389
p.H651D	TCGA-NH-A5IV	COAD	TCGA	VHTSS	DEG_SPOP_SBC_1	0.6577
p.H651D	DO49095	COAD	ICGC	VHTSS	DEG_SPOP_SBC_1	0.6577

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A8MVW5	HEPACAM family member 2	DEG_SPOP_SBC_1	189:193	VHTSS	SPOP	0.8164	More...
Q5H9F3	BCL-6 corepressor-like protein 1	DEG_SPOP_SBC_1	650:654	VHTSS	SPOP	0.9938	More...
Q8WXI7	Mucin-16	DEG_SPOP_SBC_1	1851:1855	VHTSS	SPOP	0.5519	More...
A8MX19	Putative protein FAM90A12P	DEG_SPOP_SBC_1	152:156	VHTSS	SPOP	0.9805	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons