DegronMD - Q8WXI7(MUC16)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S9727P	TCGA-02-2466	GBM	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1389
p.S9727P	DO13480	GBM	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1389
p.T11587M	TCGA-02-2485	GBM	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.3056
p.T11587M	TCGA-DU-A5TW	LGG	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.3056
p.T11587M	DO12742	GBM	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.3056
p.T11587M	DO44572	LGG	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.3056
p.L8172I	TCGA-05-4249	LUAD	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.0556
p.L8172I	TCGA-05-4249	LUAD	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.2222
p.L8172I	DO23891	LUAD	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.0556
p.L8172I	DO23891	LUAD	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.2222
p.P10190H	TCGA-05-4382	LUAD	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.P10190H	DO24900	LUAD	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.V11743M	TCGA-05-4398	LUAD	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.V11743M	TCGA-06-0875	GBM	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.V11743M	DO11830	GBM	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.V11743M	DO25847	LUAD	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.T10911N	TCGA-05-4398	LUAD	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.T10911N	DO25847	LUAD	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.P1203A	TCGA-05-4403	LUAD	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.25
p.P1203A	DO23631	LUAD	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.25
p.S9458Y	TCGA-05-4410	LUAD	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.25
p.S9458Y	DO25426	LUAD	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.25
p.S3428Y	TCGA-05-4418	LUAD	TCGA	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S3428Y	DO23814	LUAD	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S3428Y	SIDM00193	Colorectal Carcinoma	GDSC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S3428Y	ACH-000991	Colon/Colorectal Cancer	CCLE	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S3428Y	SNU-81	large intestine	COSMIC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.T7336I	TCGA-05-5425	LUAD	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7078
p.T7336I	DO26270	LUAD	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7078
p.S1200Y	TCGA-05-5425	LUAD	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.712
p.S1200Y	DO26270	LUAD	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.712
p.S1500P	TCGA-06-0125	GBM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2778
p.S1500P	DO13510	GBM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2778
p.L6486S	TCGA-06-0152	GBM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.3056
p.L6486S	DO11238	GBM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.3056
p.T11535M	TCGA-06-0209	GBM	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	TCGA-RY-A847	LGG	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	DO12520	GBM	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	DO219847	LGG	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	SIDM00396	Acute Myeloid Leukemia	GDSC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	ACH-000112	Leukemia	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11535M	SIG-M5	haematopoietic and lymphoid tissue	COSMIC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7423
p.T11089N	TCGA-06-0214	GBM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation altering degron motif	0.5944
p.T11089N	DO10960	GBM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation altering degron motif	0.5944
p.K5240E	TCGA-06-0216	GBM	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation substituting flanking lysine	0.1944
p.K5240E	DO11388	GBM	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation substituting flanking lysine	0.1944
p.S466R	TCGA-06-0646	GBM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1389
p.S466R	DO13791	GBM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1389
p.R5086H	TCGA-06-0745	GBM	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.R5086H	DO12034	GBM	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.A11752T	TCGA-06-5416	GBM	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.7139
p.A11752T	DO10880	GBM	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.7139
p.F10701L	TCGA-06-5416	GBM	TCGA	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.0833
p.F10701L	DO10880	GBM	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.0833
p.E8784K	TCGA-06-5416	GBM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1944
p.E8784K	TCGA-06-5416	GBM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.2222
p.E8784K	DO10880	GBM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1944
p.E8784K	DO10880	GBM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.2222
p.E8784K	DO220882	MELA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1944
p.E8784K	DO220882	MELA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.2222
p.T6488N	TCGA-06-5416	GBM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.5944
p.T6488N	DO10880	GBM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.5944
p.P6297H	TCGA-06-5416	GBM	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.0833
p.P6297H	DO10880	GBM	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.0833
p.T5640A	TCGA-06-5416	GBM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2222
p.T5640A	DO10880	GBM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2222
p.P3301T	TCGA-06-5416	GBM	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation altering degron motif	0.7031
p.P3301T	DO10880	GBM	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation altering degron motif	0.7031
p.A2734D	TCGA-06-5416	GBM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1667
p.A2734D	DO10880	GBM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1667
p.P2502S	TCGA-06-5416	GBM	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1667
p.P2502S	DO10880	GBM	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1667
p.P2502S	SIDM01986	Non-Small Cell Lung Carcinoma	GDSC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1667
p.V10405I	TCGA-06-6699	GBM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	TCGA-85-A4CL	LUSC	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO233749	GACA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO13893	GBM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO229055	LICA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO45454	LUSC	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO27819	MALY	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO52661	MALY	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405I	DO46897	RECA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.G10957C	TCGA-09-2044	OV	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0556
p.G10957C	DO28923	OV	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0556
p.M10796I	TCGA-09-2044	OV	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1667
p.M10796I	DO28923	OV	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1667
p.G7334W	TCGA-09-2044	OV	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6714
p.G7334W	DO28923	OV	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6714
p.L2900F	TCGA-09-2044	OV	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.587
p.L2900F	DO28923	OV	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.587
p.R4603Q	TCGA-10-0933	OV	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	TCGA-18-3409	LUSC	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	TCGA-EE-A2GL	SKCM	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	TCGA-FR-A729	SKCM	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	TCGA-J4-A67R	PRAD	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO26444	LUSC	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO222868	MELA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO29358	OV	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO49832	PRAD	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO37434	SKCM	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	DO48618	SKCM	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	SIDM01013	B-Cell Non-Hodgkin's Lymphoma	GDSC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.R4603Q	ACH-000106	Lymphoma	CCLE	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6218
p.V9265I	TCGA-12-0670	GBM	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.7076
p.V9265I	TCGA-W3-A828	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.7076
p.V9265I	DO12226	GBM	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.7076
p.V9265I	DO51273	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.7076
p.G12211E	TCGA-12-0829	GBM	TCGA	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.0833
p.G12211E	TCGA-12-0829	GBM	TCGA	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2222
p.G12211E	DO11166	GBM	ICGC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.0833
p.G12211E	DO11166	GBM	ICGC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2222
p.V8174M	TCGA-12-3650	GBM	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.2778
p.V8174M	DO12172	GBM	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.2778
p.L7732M	TCGA-13-1477	OV	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.L7732M	TCGA-13-1477	OV	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1667
p.L7732M	DO27978	OV	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.L7732M	DO27978	OV	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1667
p.T6500R	TCGA-15-0742	GBM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.2222
p.T6500R	DO13623	GBM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.2222
p.P4465H	TCGA-17-Z020	LUAD	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.3056
p.P4465H	TCGA-AX-A1C5	UCEC	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.3056
p.P4465H	DO41422	UCEC	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.3056
p.P13159H	TCGA-17-Z030	LUAD	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.7694
p.A3422S	TCGA-17-Z030	LUAD	TCGA	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation altering degron motif	0.7588
p.G2076C	TCGA-17-Z049	LUAD	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1389
p.H13130N	TCGA-17-Z061	LUAD	TCGA	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.0556
p.D4944G	TCGA-18-3406	LUSC	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1111
p.D4944G	DO26438	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1111
p.P192L	TCGA-18-3409	LUSC	TCGA	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0556
p.P192L	DO26444	LUSC	ICGC	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0556
p.G20E	TCGA-18-3409	LUSC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.1111
p.G20E	DO26444	LUSC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.1111
p.E143Q	TCGA-18-3410	LUSC	TCGA	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1111
p.E143Q	DO26456	LUSC	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1111
p.P13155T	TCGA-18-3416	LUSC	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.5919
p.P13155T	DO26423	LUSC	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.5919
p.L916V	TCGA-18-3416	LUSC	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.1667
p.L916V	DO26423	LUSC	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.1667
p.S892C	TCGA-18-4083	LUSC	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.643
p.S892C	DO26504	LUSC	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.643
p.P8968A	TCGA-18-5595	LUSC	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.3056
p.P8968A	DO27373	LUSC	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.3056
p.P12828L	TCGA-19-5956	GBM	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7582
p.P12828L	DO13863	GBM	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7582
p.S10941Y	TCGA-19-5956	GBM	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.2778
p.S10941Y	DO13863	GBM	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.2778
p.P8052H	TCGA-19-5956	GBM	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0833
p.P8052H	DO13863	GBM	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0833
p.T5628S	TCGA-19-5956	GBM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628S	TCGA-G4-6627	COAD	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628S	TCGA-P5-A5EV	LGG	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628S	DO9098	COAD	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628S	DO13863	GBM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628S	DO50160	LGG	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.S5348Y	TCGA-19-5956	GBM	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.3056
p.S5348Y	DO13863	GBM	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.3056
p.R2316I	TCGA-19-5956	GBM	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.1389
p.R2316I	DO13863	GBM	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.1389
p.S1436Y	TCGA-19-5956	GBM	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.S1436Y	DO13863	GBM	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.P7725L	TCGA-21-1079	LUSC	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7582
p.P7725L	TCGA-KK-A6E2	PRAD	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7582
p.P7725L	DO26846	LUSC	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7582
p.P7725L	DO51356	PRAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7582
p.P7725L	SIDM01618	B-Lymphoblastic Leukemia	GDSC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7582
p.V3889A	TCGA-21-1080	LUSC	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.1111
p.V3889A	DO26502	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.1111
p.S9810T	TCGA-23-2084	OV	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1389
p.S9810T	DO30310	OV	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1389
p.L1731V	TCGA-24-1418	OV	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.5654
p.L1731V	DO30860	OV	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.5654
p.K5103N	TCGA-24-1435	OV	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation substituting flanking lysine	0.1667
p.K5103N	DO31370	OV	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation substituting flanking lysine	0.1667
p.S8072Y	TCGA-24-1847	OV	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1389
p.S8072Y	DO31080	OV	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1389
p.S1733Y	TCGA-24-2035	OV	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1733Y	DO228264	LICA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1733Y	DO29598	OV	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.L7124V	TCGA-25-1326	OV	TCGA	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.0556
p.L7124V	DO28154	OV	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.0556
p.P9004A	TCGA-25-2391	OV	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation altering degron motif	0.7503
p.P9004A	DO31769	OV	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation altering degron motif	0.7503
p.T4653K	TCGA-28-1747	GBM	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.T4653K	TCGA-HT-7902	LGG	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.T4653K	DO13096	GBM	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.T4653K	DO22518	LGG	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.S6054Y	TCGA-29-1783	OV	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.6009
p.S6054Y	DO28222	OV	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.6009
p.S11054G	TCGA-2G-AAEX	TGCT	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2222
p.N3887T	TCGA-2H-A9GI	ESCA	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0556
p.V11184I	TCGA-2W-A8YY	CESC	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.25
p.V11184I	DO223732	CESC	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.25
p.Q2414P	TCGA-2W-A8YY	CESC	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.3056
p.Q2414P	DO223732	CESC	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.3056
p.T11981K	TCGA-33-4566	LUSC	TCGA	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation blocking phosphorylation signal	0.5833
p.T11981K	DO228952	LICA	ICGC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation blocking phosphorylation signal	0.5833
p.T11981K	DO26790	LUSC	ICGC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation blocking phosphorylation signal	0.5833
p.R5086L	TCGA-33-4566	LUSC	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.R5086L	DO26790	LUSC	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.T10411R	TCGA-33-4583	LUSC	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.6765
p.T10411R	DO27112	LUSC	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.6765
p.D6754E	TCGA-33-6737	LUSC	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.D6754E	DO26866	LUSC	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.T2088N	TCGA-33-AASI	LUSC	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.3056
p.T2088N	TCGA-33-AASI	LUSC	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.T2088N	DO219129	LUSC	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.3056
p.T2088N	DO219129	LUSC	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.K10450N	TCGA-33-AASL	LUSC	TCGA	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2778
p.K10450N	DO219133	LUSC	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2778
p.V10888L	TCGA-34-2596	LUSC	TCGA	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.1944
p.V10888L	DO26508	LUSC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.1944
p.P5469S	TCGA-34-2596	LUSC	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.3056
p.P5469S	DO26508	LUSC	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.3056
p.N11594K	TCGA-34-5239	LUSC	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.N11594K	TCGA-66-2742	LUSC	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.N11594K	DO26439	LUSC	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.N11594K	DO27660	LUSC	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.S7527C	TCGA-34-8454	LUSC	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.8652
p.S7527C	DO50094	LUSC	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.8652
p.I48M	TCGA-34-8454	LUSC	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.25
p.I48M	DO50094	LUSC	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.25
p.H9522D	TCGA-34-8455	LUSC	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.3056
p.H9522D	DO50095	LUSC	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.3056
p.P11092H	TCGA-35-4123	LUAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.2222
p.P11092H	TCGA-35-4123	LUAD	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.3056
p.P11092H	TCGA-35-4123	LUAD	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.1944
p.P11092H	DO26394	LUAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.2222
p.P11092H	DO26394	LUAD	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.3056
p.P11092H	DO26394	LUAD	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.1944
p.S3428C	TCGA-37-3792	LUSC	TCGA	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S3428C	DO27192	LUSC	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.2778
p.S10856C	TCGA-37-4132	LUSC	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.2222
p.S10856C	TCGA-37-4132	LUSC	TCGA	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.0833
p.S10856C	TCGA-37-4132	LUSC	TCGA	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.25
p.S10856C	DO26528	LUSC	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.2222
p.S10856C	DO26528	LUSC	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.0833
p.S10856C	DO26528	LUSC	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.25
p.L12013M	TCGA-37-A5EL	LUSC	TCGA	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.1667
p.L12013M	DO223718	LUSC	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.1667
p.S1507I	TCGA-37-A5EN	LUSC	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0833
p.S1507I	DO223720	LUSC	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0833
p.D2919E	TCGA-39-5034	LUSC	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1667
p.D2919E	DO26854	LUSC	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1667
p.E450K	TCGA-3N-A9WC	SKCM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	TCGA-EE-A2GJ	SKCM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	TCGA-EO-A3B0	UCEC	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	TCGA-FD-A62P	BLCA	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	DO44054	BLCA	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	DO37746	SKCM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	DO51234	SKCM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.E450K	DO219773	UCEC	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.591
p.S348F	TCGA-3N-A9WC	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	TCGA-BF-AAP0	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	TCGA-EE-A3AC	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	DO220889	MELA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	DO222644	MELA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	DO37631	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	DO51234	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	DO219462	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	SIDM01750	Melanoma	GDSC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.S348F	ACH-000801	Skin Cancer	CCLE	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.T1198M	TCGA-41-3393	GBM	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.8534
p.T1198M	TCGA-AJ-A8CW	UCEC	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.8534
p.T1198M	DO12646	GBM	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.8534
p.T1198M	DO52400	UCEC	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.8534
p.E13923D	TCGA-43-2581	LUSC	TCGA	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1667
p.E13923D	DO230309	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1667
p.E13923D	DO26602	LUSC	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1667
p.S5652R	TCGA-43-2581	LUSC	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2222
p.S5652R	DO26602	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2222
p.S1671Y	TCGA-43-2581	LUSC	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0833
p.S1671Y	TCGA-B5-A1MR	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0833
p.S1671Y	DO26602	LUSC	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0833
p.S1671Y	DO41758	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0833
p.P7813L	TCGA-43-6770	LUSC	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.P7813L	DO27644	LUSC	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.S10777C	TCGA-43-8116	LUSC	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7541
p.S10777C	DO27349	LUSC	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7541
p.S7493Y	TCGA-44-3918	LUAD	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation blocking phosphorylation signal	0.5833
p.S7493Y	DO23732	LUAD	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation blocking phosphorylation signal	0.5833
p.A10943S	TCGA-44-5643	LUAD	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation altering degron motif	0.7588
p.A10943S	DO25508	LUAD	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation altering degron motif	0.7588
p.T2422K	TCGA-44-5644	LUAD	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.25
p.T2422K	DO25153	LUAD	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.25
p.I8770V	TCGA-44-6774	LUAD	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.25
p.I8770V	TCGA-44-6774	LUAD	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.1667
p.I8770V	DO25000	LUAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.25
p.I8770V	DO25000	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.1667
p.L4599M	TCGA-44-6777	LUAD	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.2222
p.L4599M	DO23645	LUAD	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.2222
p.P11695Q	TCGA-44-7662	LUAD	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7035
p.P11695Q	DO23597	LUAD	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7035
p.A11387D	TCGA-44-7669	LUAD	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1111
p.A11387D	DO229027	LICA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1111
p.A11387D	DO229035	LICA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1111
p.A11387D	DO25262	LUAD	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1111
p.V6505E	TCGA-49-4488	LUAD	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0833
p.V6505E	DO24750	LUAD	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0833
p.R953I	TCGA-49-4488	LUAD	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0833
p.R953I	DO24750	LUAD	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0833
p.T11070I	TCGA-49-AAR9	LUAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.0556
p.T11070I	DO218921	LUAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.0556
p.N12970S	TCGA-49-AARE	LUAD	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.0556
p.N12970S	TCGA-49-AARE	LUAD	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0833
p.N12970S	DO218922	LUAD	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.0556
p.N12970S	DO218922	LUAD	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0833
p.S311P	TCGA-49-AARE	LUAD	TCGA	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7863
p.S311P	DO218922	LUAD	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7863
p.T10549S	TCGA-49-AARN	LUAD	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.6005
p.T10549S	DO218923	LUAD	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.6005
p.P7716L	TCGA-49-AARN	LUAD	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.P7716L	TCGA-FW-A3R5	SKCM	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.P7716L	DO218923	LUAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.P7716L	DO37406	SKCM	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.T8767S	TCGA-49-AARQ	LUAD	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.T8767S	TCGA-49-AARQ	LUAD	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.T8767S	DO51189	LUAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.T8767S	DO51189	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.T12837A	TCGA-4W-AA9R	GBM	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0556
p.T12837A	TCGA-4W-AA9R	GBM	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1944
p.T12837A	DO219107	GBM	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0556
p.T12837A	DO219107	GBM	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1944
p.G6D	TCGA-4X-A9FC	THYM	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.2778
p.L10937V	TCGA-4Z-AA80	BLCA	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	TCGA-4Z-AA80	BLCA	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.L10937V	TCGA-66-2785	LUSC	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	TCGA-66-2785	LUSC	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.L10937V	TCGA-E7-A6MD	BLCA	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	TCGA-E7-A6MD	BLCA	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.L10937V	DO218986	BLCA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	DO218986	BLCA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.L10937V	DO219015	BLCA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	DO219015	BLCA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.L10937V	DO26520	LUSC	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.L10937V	DO26520	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.S10845G	TCGA-4Z-AA80	BLCA	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1944
p.S10845G	DO218986	BLCA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1944
p.E1659K	TCGA-4Z-AA80	BLCA	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation altering degron motif	0.591
p.E1659K	DO218986	BLCA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation altering degron motif	0.591
p.P3244Q	TCGA-50-5045	LUAD	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.0833
p.P3244Q	DO23723	LUAD	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.0833
p.T7989R	TCGA-50-5931	LUAD	TCGA	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7876
p.T7989R	DO24980	LUAD	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7876
p.G12360W	TCGA-50-7109	LUAD	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6714
p.G12360W	DO24487	LUAD	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6714
p.T8894A	TCGA-52-7810	LUSC	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.0556
p.T8894A	DO27381	LUSC	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.0556
p.S3006L	TCGA-52-7812	LUSC	TCGA	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation altering degron motif	0.7667
p.S3006L	DO27067	LUSC	ICGC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation altering degron motif	0.7667
p.S3006L	SIDM01011	B-Cell Non-Hodgkin's Lymphoma	GDSC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation altering degron motif	0.7667
p.P5359L	TCGA-55-6712	LUAD	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.P5359L	DO25310	LUAD	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.A11084D	TCGA-55-6979	LUAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6682
p.A11084D	DO24110	LUAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6682
p.P7725Q	TCGA-55-6979	LUAD	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7035
p.P7725Q	DO24110	LUAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7035
p.L2407I	TCGA-55-7281	LUAD	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1111
p.L2407I	DO25985	LUAD	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1111
p.P9445S	TCGA-55-7994	LUAD	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.25
p.P9445S	TCGA-55-7994	LUAD	TCGA	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.2222
p.P9445S	DO45311	LUAD	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.25
p.P9445S	DO45311	LUAD	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.2222
p.E1826V	TCGA-55-7994	LUAD	TCGA	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.6582
p.E1826V	TCGA-55-7994	LUAD	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.7693
p.E1826V	DO45311	LUAD	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.6582
p.E1826V	DO45311	LUAD	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.7693
p.P1491H	TCGA-55-7994	LUAD	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.7694
p.P1491H	DO45311	LUAD	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.7694
p.S12838A	TCGA-55-8089	LUAD	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1667
p.S12838A	DO23690	LUAD	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1667
p.D10848E	TCGA-55-8089	LUAD	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1111
p.D10848E	DO23690	LUAD	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1111
p.P1970Q	TCGA-55-8203	LUAD	TCGA	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.P1970Q	DO218928	LUAD	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.T8779M	TCGA-55-8207	LUAD	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.8534
p.T8779M	TCGA-55-8207	LUAD	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.8534
p.T8779M	DO233251	GACA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.8534
p.T8779M	DO233251	GACA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.8534
p.T8779M	DO45351	LUAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.8534
p.T8779M	DO45351	LUAD	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.8534
p.Q5473H	TCGA-55-8301	LUAD	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.Q5473H	DO24682	LUAD	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.A11246S	TCGA-55-8506	LUAD	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6477
p.A11246S	DO45390	LUAD	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6477
p.L3285H	TCGA-55-8508	LUAD	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.0556
p.L3285H	DO45341	LUAD	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.0556
p.A11081P	TCGA-55-A491	LUAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6392
p.A11081P	DO25787	LUAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6392
p.M1192I	TCGA-55-A494	LUAD	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.2222
p.M1192I	DO23794	LUAD	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.2222
p.E6878Q	TCGA-55-A4DF	LUAD	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2222
p.E6878Q	DO45318	LUAD	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2222
p.P2721Q	TCGA-55-A4DF	LUAD	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.25
p.P2721Q	DO45318	LUAD	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.25
p.G7273A	TCGA-56-6546	LUSC	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.0556
p.G7273A	DO26542	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.0556
p.T976A	TCGA-56-7731	LUSC	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0556
p.T976A	DO45527	LUSC	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0556
p.I8765M	TCGA-56-8201	LUSC	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1111
p.I8765M	DO223724	LUSC	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1111
p.G8104C	TCGA-56-A4BY	LUSC	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.G8104C	DO44802	LICA	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.G8104C	DO45457	LUSC	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.V6333F	TCGA-56-A62T	LUSC	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7068
p.V6333F	DO219144	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7068
p.I6877R	TCGA-58-8391	LUSC	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1944
p.I6877R	DO45440	LUSC	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1944
p.E4617K	TCGA-5L-AAT1	BRCA	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.0556
p.E4617K	TCGA-A8-A093	BRCA	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.0556
p.E4617K	DO4161	BRCA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.0556
p.E4617K	DO219594	BRCA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.0556
p.R10809Q	TCGA-5M-AAT6	COAD	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.25
p.R10809Q	TCGA-E6-A1LX	UCEC	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.25
p.R10809Q	DO223703	COAD	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.25
p.R10809Q	DO229456	SKCA	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.25
p.R10809Q	DO41020	UCEC	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.25
p.R883K	TCGA-60-2709	LUSC	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.R883K	DO27096	LUSC	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.G2911V	TCGA-60-2714	LUSC	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation altering degron motif	0.6421
p.G2911V	DO26530	LUSC	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation altering degron motif	0.6421
p.V11041M	TCGA-61-2095	OV	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.V11041M	DO234304	ESAD	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.V11041M	DO27987	OV	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.P10646S	TCGA-61-2110	OV	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1667
p.P10646S	DO27979	OV	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1667
p.G12370A	TCGA-62-A46O	LUAD	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1389
p.G12370A	DO26240	LUAD	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1389
p.E8212K	TCGA-62-A46O	LUAD	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.591
p.E8212K	DO26240	LUAD	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.591
p.S4607I	TCGA-63-6202	LUSC	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.623
p.S4607I	DO26560	LUSC	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.623
p.V13602M	TCGA-63-A5MW	LUSC	TCGA	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation altering degron motif	0.7208
p.V13602M	DO219169	LUSC	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation altering degron motif	0.7208
p.D11399Y	TCGA-64-1676	LUAD	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.6214
p.D11399Y	DO23629	LUAD	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.6214
p.S10795T	TCGA-64-5775	LUAD	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1389
p.S10795T	DO26025	LUAD	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1389
p.P13155H	TCGA-66-2754	LUSC	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6583
p.P13155H	DO27612	LUSC	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6583
p.P7725S	TCGA-66-2769	LUSC	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.6752
p.P7725S	DO26522	LUSC	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.6752
p.P7725S	SIDM00011	Melanoma	GDSC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.6752
p.P7725S	ACH-000477	Skin Cancer	CCLE	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.6752
p.T10911I	TCGA-66-2771	LUSC	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.T10911I	DO26870	LUSC	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0556
p.P5623R	TCGA-66-2773	LUSC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7512
p.P5623R	DO26536	LUSC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7512
p.P12372Q	TCGA-66-2783	LUSC	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0833
p.P12372Q	DO26452	LUSC	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0833
p.T1466R	TCGA-66-2785	LUSC	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.T1466R	DO26520	LUSC	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.P541A	TCGA-66-2785	LUSC	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.P541A	DO26520	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.L5459M	TCGA-67-3770	LUAD	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.L5459M	DO23932	LUAD	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.H3714Q	TCGA-68-8250	LUSC	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.H3714Q	DO26993	LUSC	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.S7331N	TCGA-68-A59J	LUSC	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.2778
p.S7331N	DO49085	LUSC	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.2778
p.R6761M	TCGA-69-7973	LUAD	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.3056
p.R6761M	DO23870	LUAD	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.3056
p.R6761M	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.3056
p.R6761M	ACH-002272	Lymphoma	CCLE	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.3056
p.R6761M	MHH-PREB-1	haematopoietic and lymphoid tissue	COSMIC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.3056
p.P7725R	TCGA-69-7978	LUAD	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7512
p.P7725R	DO24920	LUAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7512
p.V10405D	TCGA-69-7980	LUAD	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.V10405D	DO23678	LUAD	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.2222
p.L3733Q	TCGA-73-4670	LUAD	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1667
p.L3733Q	DO25350	LUAD	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1667
p.P11293L	TCGA-74-6578	GBM	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.P11293L	DO14007	GBM	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.G4473R	TCGA-75-5126	LUAD	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.25
p.G4473R	DO23711	LUAD	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.25
p.H12349N	TCGA-75-6211	LUAD	TCGA	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.2222
p.H12349N	TCGA-75-6211	LUAD	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0556
p.H12349N	DO25173	LUAD	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.2222
p.H12349N	DO25173	LUAD	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0556
p.M11501I	TCGA-76-6656	GBM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.M11501I	TCGA-CN-6010	HNSC	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.M11501I	DO13671	GBM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.M11501I	DO14766	HNSC	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.S9453F	TCGA-77-6842	LUSC	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation altering degron motif	0.6871
p.S9453F	DO27413	LUSC	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation altering degron motif	0.6871
p.S7995T	TCGA-77-A5G1	LUSC	TCGA	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.1667
p.S7995T	DO50096	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.1667
p.S5360Y	TCGA-77-A5G6	LUSC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1389
p.S5360Y	DO50097	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1389
p.P7333H	TCGA-78-7161	LUAD	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7694
p.P7333H	DO228978	LICA	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7694
p.P7333H	DO25975	LUAD	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7694
p.S7485Y	TCGA-78-7539	LUAD	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.712
p.S7485Y	DO26210	LUAD	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.712
p.D8095Y	TCGA-85-6798	LUSC	TCGA	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.25
p.D8095Y	TCGA-85-6798	LUSC	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.25
p.D8095Y	DO27295	LUSC	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.25
p.D8095Y	DO27295	LUSC	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.25
p.P8052L	TCGA-85-7950	LUSC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0833
p.P8052L	DO26878	LUSC	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0833
p.L7809V	TCGA-85-8481	LUSC	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation altering degron motif	0.5654
p.L7809V	DO45465	LUSC	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation altering degron motif	0.5654
p.G10451D	TCGA-85-8580	LUSC	TCGA	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.G10451D	DO50970	LICA	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.G10451D	DO45549	LUSC	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.L1195V	TCGA-85-8666	LUSC	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.3056
p.L1195V	DO45547	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.3056
p.I5358M	TCGA-85-A511	LUSC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1944
p.I5358M	DO45509	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1944
p.H11077N	TCGA-86-8055	LUAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.25
p.H11077N	TCGA-86-8055	LUAD	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1111
p.H11077N	DO25554	LUAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.25
p.H11077N	DO25554	LUAD	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1111
p.T4030A	TCGA-86-8073	LUAD	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1944
p.T4030A	DO23624	LUAD	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1944
p.F690I	TCGA-86-8669	LUAD	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1667
p.F690I	DO25574	LUAD	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1667
p.G12829W	TCGA-86-8673	LUAD	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.6714
p.G12829W	DO26260	LUAD	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.6714
p.S8064Y	TCGA-86-8673	LUAD	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation altering degron motif	0.712
p.S8064Y	DO26260	LUAD	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation altering degron motif	0.712
p.Q2887K	TCGA-86-8673	LUAD	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.2222
p.Q2887K	DO26260	LUAD	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.2222
p.G13616R	TCGA-90-A4ED	LUSC	TCGA	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0556
p.G13616R	DO45482	LUSC	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0556
p.P10880A	TCGA-91-6828	LUAD	TCGA	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.7503
p.P10880A	DO26150	LUAD	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.7503
p.P1084Q	TCGA-91-6835	LUAD	TCGA	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1389
p.P1084Q	DO26082	LUAD	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1389
p.I3220N	TCGA-93-8067	LUAD	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.1111
p.I3220N	DO25113	LUAD	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.1111
p.G10858A	TCGA-94-A5I4	LUSC	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.2778
p.G10858A	TCGA-94-A5I4	LUSC	TCGA	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.1389
p.G10858A	TCGA-94-A5I4	LUSC	TCGA	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.3056
p.G10858A	DO219175	LUSC	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.2778
p.G10858A	DO219175	LUSC	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.1389
p.G10858A	DO219175	LUSC	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.3056
p.V208E	TCGA-94-A5I4	LUSC	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7693
p.V208E	DO219175	LUSC	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7693
p.T7968S	TCGA-95-7039	LUAD	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.0556
p.T7968S	DO23907	LUAD	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.0556
p.T7968S	SIDM01986	Non-Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.0556
p.P712T	TCGA-95-7039	LUAD	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.0833
p.P712T	DO23907	LUAD	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.0833
p.T13149N	TCGA-95-7562	LUAD	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.7055
p.T13149N	DO51196	LUAD	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.7055
p.G8208W	TCGA-95-7562	LUAD	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.6714
p.G8208W	DO51196	LUAD	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.6714
p.T8159A	TCGA-95-7567	LUAD	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7139
p.T8159A	DO25564	LUAD	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7139
p.A2100S	TCGA-95-7567	LUAD	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.3056
p.A2100S	DO25564	LUAD	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.3056
p.A10651P	TCGA-95-A4VN	LUAD	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.A10651P	TCGA-CV-7091	HNSC	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.A10651P	DO14212	HNSC	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.A10651P	DO51199	LUAD	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.R12975W	TCGA-96-A4JK	LUSC	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975W	TCGA-96-A4JK	LUSC	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975W	TCGA-96-A4JK	LUSC	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.R12975W	DO45442	LUSC	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975W	DO45442	LUSC	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975W	DO45442	LUSC	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.R12975W	SIDM00632	Non-Cancerous	GDSC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975W	SIDM00632	Non-Cancerous	GDSC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975W	SIDM00632	Non-Cancerous	GDSC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.R12975W	IM-9	haematopoietic and lymphoid tissue	COSMIC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975W	IM-9	haematopoietic and lymphoid tissue	COSMIC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975W	IM-9	haematopoietic and lymphoid tissue	COSMIC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.V11250F	TCGA-97-7546	LUAD	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.7068
p.V11250F	DO23762	LUAD	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.7068
p.I300K	TCGA-97-8172	LUAD	TCGA	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1389
p.I300K	DO26384	LUAD	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1389
p.T11310S	TCGA-99-8025	LUAD	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.6005
p.T11310S	DO24255	LUAD	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.6005
p.S7692F	TCGA-99-8028	LUAD	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.S7692F	DO23561	LUAD	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P1758T	TCGA-A2-A0T0	BRCA	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7031
p.P1758T	DO4122	BRCA	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7031
p.T8895P	TCGA-A2-A25D	BRCA	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.0833
p.T8895P	DO1262	BRCA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.0833
p.Q2414K	TCGA-A4-7583	KIRP	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.3056
p.Q2414K	DO20870	KIRP	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.3056
p.A9325D	TCGA-A4-7584	KIRP	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.7793
p.A9325D	DO20869	KIRP	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.7793
p.T10409R	TCGA-A4-8630	KIRP	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.7876
p.T10409R	DO44489	KIRP	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.7876
p.P11768S	TCGA-A5-A0G1	UCEC	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1389
p.P11768S	DO42472	UCEC	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1389
p.E11873D	TCGA-A5-A0G2	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.1667
p.E11873D	DO222884	COCA	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.1667
p.E11873D	DO41235	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.1667
p.R11615M	TCGA-A5-A0G2	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.25
p.R11615M	DO41235	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.25
p.E11259K	TCGA-A5-A0G2	UCEC	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.E11259K	DO41235	UCEC	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.A10829T	TCGA-A5-A0G2	UCEC	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1389
p.A10829T	DO41235	UCEC	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1389
p.N6596H	TCGA-A5-A0G2	UCEC	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.3056
p.N6596H	DO41235	UCEC	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.3056
p.T1466I	TCGA-A5-A0G2	UCEC	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.T1466I	DO41235	UCEC	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.0833
p.P13303L	TCGA-A5-A0GW	UCEC	TCGA	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.0833
p.P13303L	DO41103	UCEC	ICGC	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.0833
p.R7820M	TCGA-A5-A1OF	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.1111
p.R7820M	DO42568	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.1111
p.T4032A	TCGA-A5-A1OF	UCEC	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1389
p.T4032A	DO42568	UCEC	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1389
p.T3449I	TCGA-A5-A1OF	UCEC	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.T3449I	DO42568	UCEC	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.E10322D	TCGA-A5-A2K5	UCEC	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.0833
p.E10322D	DO41379	UCEC	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.0833
p.R8991I	TCGA-A5-A2K5	UCEC	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	TCGA-AZ-4315	COAD	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	TCGA-EO-A3B0	UCEC	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	DO8842	COAD	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	DO219773	UCEC	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	DO41379	UCEC	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	SIDM00578	Neuroblastoma	GDSC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.R8991I	ACH-000804	Neuroblastoma	CCLE	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.0833
p.N6065T	TCGA-A5-A2K5	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1111
p.N6065T	DO41379	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1111
p.M4867I	TCGA-A5-A2K5	UCEC	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.M4867I	TCGA-FW-A5DY	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.M4867I	DO223076	ESCA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.M4867I	DO47257	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.M4867I	DO41379	UCEC	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.A1458T	TCGA-A5-A2K5	UCEC	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.3056
p.A1458T	DO41379	UCEC	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.3056
p.G12674E	TCGA-A6-2686	COAD	TCGA	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.25
p.G12674E	DO7828	COAD	ICGC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.25
p.T9737I	TCGA-A6-2686	COAD	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7078
p.T9737I	DO7828	COAD	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7078
p.K10171E	TCGA-A6-6648	COAD	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.K10171E	DO10196	COAD	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.T5613I	TCGA-A7-A0CJ	BRCA	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.T5613I	DO2874	BRCA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S1734Y	TCGA-A8-A0A9	BRCA	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1734Y	DO2473	BRCA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1734Y	SIDM00118	Colorectal Carcinoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1734Y	ACH-001081	Colon/Colorectal Cancer	CCLE	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.S1734Y	HCC2998	large intestine	COSMIC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.712
p.G5315D	TCGA-AA-3510	COAD	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.0833
p.G5315D	DO7783	COAD	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.0833
p.S4937R	TCGA-AA-3510	COAD	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.3056
p.S4937R	DO7783	COAD	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.3056
p.S9169T	TCGA-AA-3819	COAD	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.1389
p.S9169T	DO10590	COAD	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.1389
p.P12666H	TCGA-AA-3833	COAD	TCGA	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.3056
p.P12666H	DO9796	COAD	ICGC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.3056
p.T7330K	TCGA-AA-3837	COAD	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation blocking phosphorylation signal	0.6944
p.T7330K	DO10502	COAD	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation blocking phosphorylation signal	0.6944
p.A8151T	TCGA-AA-3845	COAD	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1389
p.A8151T	DO10020	COAD	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1389
p.T6601A	TCGA-AA-3845	COAD	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation altering degron motif	0.7139
p.T6601A	DO10020	COAD	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation altering degron motif	0.7139
p.S9554F	TCGA-AA-3848	COAD	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.3056
p.S9554F	DO9740	COAD	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.3056
p.P13159S	TCGA-AA-3947	COAD	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.P13159S	DO8192	COAD	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.P13159S	SIDM00003	Melanoma	GDSC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.P13159S	ACH-000884	Skin Cancer	CCLE	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.P13159S	ACH-002159	Skin Cancer	CCLE	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.P13159S	M14	skin	COSMIC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6752
p.D11236Y	TCGA-AA-3977	COAD	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1111
p.D11236Y	DO8730	COAD	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1111
p.S10786L	TCGA-AA-3977	COAD	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1111
p.S10786L	DO8730	COAD	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1111
p.S10786L	DO222818	MELA	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1111
p.S10342Y	TCGA-AA-3977	COAD	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation blocking phosphorylation signal	0.5833
p.S10342Y	DO8730	COAD	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation blocking phosphorylation signal	0.5833
p.S3711Y	TCGA-AA-3977	COAD	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.S3711Y	DO8730	COAD	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.S3711Y	DO222762	COCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.S1157Y	TCGA-AA-3977	COAD	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.2222
p.S1157Y	DO8730	COAD	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.2222
p.A4923T	TCGA-AA-3984	COAD	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.0833
p.A4923T	DO9002	COAD	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.0833
p.S10778L	TCGA-AA-A00N	COAD	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	TCGA-DM-A285	COAD	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	TCGA-EE-A181	SKCM	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	DO9490	COAD	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	DO9876	COAD	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	DO220906	MELA	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.S10778L	DO37444	SKCM	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7667
p.R5610W	TCGA-AA-A00N	COAD	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0556
p.R5610W	DO9876	COAD	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0556
p.R5610W	DO220851	MELA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0556
p.A2425T	TCGA-AA-A00N	COAD	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1667
p.A2425T	TCGA-ER-A194	SKCM	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1667
p.A2425T	DO9876	COAD	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1667
p.A2425T	DO47646	SKCM	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1667
p.K358N	TCGA-AA-A00N	COAD	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.K358N	DO9876	COAD	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2778
p.L13771M	TCGA-AA-A010	COAD	TCGA	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.0833
p.T11591A	TCGA-AA-A010	COAD	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1944
p.L11545M	TCGA-AA-A010	COAD	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.0833
p.L11545M	DO50403	ESAD	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.0833
p.L11545M	ACH-001458	Colon/Colorectal Cancer	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.0833
p.R10422Q	TCGA-AA-A010	COAD	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.R10422Q	SIDM00604	Oral Cavity Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.R10422Q	SIDM01609	Endometrial Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.R10422Q	ACH-000972	Endometrial/Uterine Cancer	CCLE	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.R10422Q	ACH-001542	Head and Neck Cancer	CCLE	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.R10422Q	KON	upper aerodigestive tract	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.D8977Y	TCGA-AA-A010	COAD	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.2222
p.D8977Y	TCGA-B5-A0JY	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.2222
p.D8977Y	TCGA-DF-A2KV	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.2222
p.D8977Y	DO219771	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.2222
p.D8977Y	DO43041	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.2222
p.S8175P	TCGA-AA-A010	COAD	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.I4872N	TCGA-AA-A010	COAD	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.1667
p.V3224A	TCGA-AA-A010	COAD	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2222
p.A1011T	TCGA-AA-A010	COAD	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.25
p.A1011T	ACH-000791	Lung Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.25
p.T1841I	TCGA-AA-A01I	COAD	TCGA	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.0833
p.T1841I	TCGA-AA-A01I	COAD	TCGA	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.0556
p.T1841I	DO10510	COAD	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.0833
p.T1841I	DO10510	COAD	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.0556
p.T1187S	TCGA-AA-A01P	COAD	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.0833
p.T1187S	DO8642	COAD	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.0833
p.Y12657C	TCGA-AA-A01R	COAD	TCGA	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0556
p.Y12657C	DO7934	COAD	ICGC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0556
p.P8672H	TCGA-AD-5900	COAD	TCGA	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.1944
p.P8672H	DO8514	COAD	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.1944
p.H9513Y	TCGA-AD-6895	COAD	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513Y	DO8938	COAD	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.L8682P	TCGA-AD-6895	COAD	TCGA	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.L8682P	TCGA-AD-6895	COAD	TCGA	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1944
p.L8682P	DO8938	COAD	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.L8682P	DO8938	COAD	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1944
p.E522K	TCGA-AF-5654	READ	TCGA	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522K	DO36647	READ	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.P1969T	TCGA-AG-3890	READ	TCGA	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.2222
p.P1969T	TCGA-BH-A0BP	BRCA	TCGA	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.2222
p.P1969T	DO4056	BRCA	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.2222
p.P1969T	DO36431	READ	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.2222
p.V12511M	TCGA-AG-3896	READ	TCGA	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7208
p.V12511M	DO37259	READ	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7208
p.R12039W	TCGA-AG-A002	READ	TCGA	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.2222
p.R12039W	TCGA-AG-A002	READ	TCGA	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0833
p.R12039W	TCGA-D3-A2JK	SKCM	TCGA	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.2222
p.R12039W	TCGA-D3-A2JK	SKCM	TCGA	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0833
p.R12039W	DO222432	ESCA	ICGC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.2222
p.R12039W	DO222432	ESCA	ICGC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0833
p.R12039W	DO37619	SKCM	ICGC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.2222
p.R12039W	DO37619	SKCM	ICGC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0833
p.S11764F	TCGA-AG-A002	READ	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.6944
p.S11764F	TCGA-AG-A002	READ	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation blocking phosphorylation signal	0.5556
p.S11054N	TCGA-AG-A002	READ	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2222
p.S10919Y	TCGA-AG-A002	READ	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S10919Y	DO234395	ESAD	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S2427F	TCGA-AG-A002	READ	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1111
p.S2078A	TCGA-AG-A002	READ	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1944
p.A6302E	TCGA-AG-A011	READ	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.A10651S	TCGA-AG-A01Y	READ	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.A10651S	DO37396	READ	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.3056
p.S1720R	TCGA-AG-A036	READ	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.S1720R	DO37245	READ	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.P2324A	TCGA-AJ-A23N	UCEC	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.6392
p.P2324A	DO43594	UCEC	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.6392
p.M11687T	TCGA-AJ-A3EK	UCEC	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1111
p.M11687T	DO41584	UCEC	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1111
p.A6331T	TCGA-AJ-A3EK	UCEC	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2778
p.A6331T	TCGA-FI-A2D5	UCEC	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2778
p.A6331T	DO41584	UCEC	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2778
p.A6331T	DO41331	UCEC	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2778
p.P12828H	TCGA-AJ-A3EL	UCEC	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7694
p.P12828H	DO227531	PACA	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7694
p.P12828H	DO41542	UCEC	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7694
p.S5361Y	TCGA-AJ-A3EL	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1111
p.S5361Y	DO41542	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1111
p.E1016D	TCGA-AJ-A3EL	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1111
p.E1016D	DO41542	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1111
p.E341K	TCGA-AJ-A3EL	UCEC	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.E341K	TCGA-BR-6802	STAD	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.E341K	DO230313	COCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.E341K	DO219878	SKCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.E341K	DO38332	STAD	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.E341K	DO41542	UCEC	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.G6499E	TCGA-AJ-A3OK	UCEC	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.25
p.G6499E	DO43602	UCEC	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.25
p.S4781C	TCGA-AJ-A3QS	UCEC	TCGA	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.7541
p.S4781C	DO41349	UCEC	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.7541
p.S44C	TCGA-AJ-A3QS	UCEC	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation altering degron motif	0.7541
p.S44C	DO41349	UCEC	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation altering degron motif	0.7541
p.P13291S	TCGA-AN-A046	BRCA	TCGA	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation altering degron motif	0.5641
p.P13291S	DO1285	BRCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation altering degron motif	0.5641
p.T10537M	TCGA-AO-A124	BRCA	TCGA	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation altering degron motif	0.7423
p.T10537M	DO1287	BRCA	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation altering degron motif	0.7423
p.Q1450K	TCGA-AO-A124	BRCA	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation altering degron motif	0.5833
p.Q1450K	DO1287	BRCA	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation altering degron motif	0.5833
p.T10186I	TCGA-AP-A051	UCEC	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation altering degron motif	0.7078
p.T10186I	DO42673	UCEC	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation altering degron motif	0.7078
p.A10887T	TCGA-AP-A056	UCEC	TCGA	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2222
p.A10887T	DO43971	UCEC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2222
p.E9319D	TCGA-AP-A059	UCEC	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1667
p.E9319D	DO41361	UCEC	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1667
p.E9319D	SIDM00721	Small Cell Lung Carcinoma	GDSC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1667
p.E9319D	ACH-002171	Lung Cancer	CCLE	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1667
p.E9319D	NCI-H250	lung	COSMIC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1667
p.K3976N	TCGA-AP-A059	UCEC	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation substituting flanking lysine	0.3056
p.K3976N	DO41361	UCEC	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation substituting flanking lysine	0.3056
p.R15H	TCGA-AP-A059	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15H	TCGA-AX-A1C4	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15H	DO42480	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15H	DO41361	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15H	ACH-001991	Primary	CCLE	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.S7285T	TCGA-AP-A05H	UCEC	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation altering degron motif	0.6005
p.S7285T	DO43546	UCEC	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation altering degron motif	0.6005
p.E11809Q	TCGA-AP-A0LF	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation altering degron motif	0.5633
p.E11809Q	DO43610	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation altering degron motif	0.5633
p.P11429S	TCGA-AP-A0LM	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.6752
p.P11429S	DO43306	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.6752
p.A10801V	TCGA-AP-A0LM	UCEC	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	TCGA-BR-8487	STAD	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	TCGA-F5-6571	READ	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	DO222843	MELA	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	DO36874	READ	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	DO47867	STAD	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	DO43306	UCEC	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	SIDM00542	Glioblastoma	GDSC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	ACH-002227	Brain Cancer	CCLE	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.A10801V	D-392MG	central nervous system	COSMIC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.3056
p.T2882A	TCGA-AP-A0LM	UCEC	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.0833
p.T2882A	DO43306	UCEC	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.0833
p.A361S	TCGA-AP-A0LM	UCEC	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1944
p.A361S	DO43306	UCEC	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1944
p.G13163D	TCGA-AP-A1DV	UCEC	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.G13163D	DO43186	UCEC	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.E11178D	TCGA-AP-A1DV	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.5647
p.E11178D	DO8898	COAD	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.5647
p.E11178D	DO43186	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.5647
p.E10689D	TCGA-AP-A1DV	UCEC	TCGA	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation altering degron motif	0.5647
p.E10689D	DO43186	UCEC	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation altering degron motif	0.5647
p.S10023Y	TCGA-AP-A1DV	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023Y	DO43186	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S9166N	TCGA-AP-A1DV	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2222
p.S9166N	DO43186	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2222
p.D5616Y	TCGA-AP-A1DV	UCEC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2222
p.D5616Y	DO43186	UCEC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2222
p.R5612I	TCGA-AP-A1DV	UCEC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1111
p.R5612I	DO43186	UCEC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1111
p.A1730S	TCGA-AP-A1DV	UCEC	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7588
p.A1730S	DO43186	UCEC	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7588
p.P212Q	TCGA-AP-A1E0	UCEC	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7035
p.P212Q	DO43154	UCEC	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7035
p.P10833S	TCGA-AX-A05Z	UCEC	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.P10833S	DO40884	UCEC	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.E2421K	TCGA-AX-A05Z	UCEC	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.E2421K	DO40884	UCEC	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.T11816A	TCGA-AX-A06F	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.2222
p.T11816A	DO41752	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.2222
p.P5650S	TCGA-AX-A06F	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.P5650S	DO41752	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.P5650S	SIDM01045	Endometrial Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.P5650S	ACH-000978	Endometrial/Uterine Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.P5650S	EN	endometrium	COSMIC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.S9156Y	TCGA-AX-A0J0	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.S9156Y	TCGA-CC-A7IF	LIHC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.S9156Y	DO52177	LIHC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.S9156Y	DO41133	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.S9149Y	TCGA-AX-A0J0	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9149Y	TCGA-PG-A6IB	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9149Y	DO52419	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9149Y	DO41133	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S6046Y	TCGA-AX-A0J0	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1389
p.S6046Y	DO41133	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1389
p.T5225A	TCGA-AX-A0J0	UCEC	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.2778
p.T5225A	DO41133	UCEC	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.2778
p.P548S	TCGA-AX-A0J1	UCEC	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.3056
p.P548S	DO41199	UCEC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.3056
p.S518L	TCGA-AX-A1C8	UCEC	TCGA	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1667
p.S518L	DO43338	UCEC	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1667
p.F10667L	TCGA-AX-A1CI	UCEC	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.0556
p.F10667L	DO42544	UCEC	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.0556
p.E8764K	TCGA-AX-A2HC	UCEC	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0833
p.E8764K	TCGA-CA-6718	COAD	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0833
p.E8764K	DO7801	COAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0833
p.E8764K	DO41572	UCEC	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0833
p.S8053Y	TCGA-AX-A2HC	UCEC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1111
p.S8053Y	DO41572	UCEC	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1111
p.R704I	TCGA-AX-A2HC	UCEC	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.R704I	TCGA-D5-6537	COAD	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.R704I	DO9530	COAD	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.R704I	DO41572	UCEC	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.P2910H	TCGA-AX-A2HD	UCEC	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation altering degron motif	0.7694
p.P2910H	DO42608	UCEC	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation altering degron motif	0.7694
p.S9171L	TCGA-AX-A3FT	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9171L	DO222644	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9171L	DO222662	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.S9171L	DO40801	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.0833
p.A2734V	TCGA-AX-A3FT	UCEC	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1667
p.A2734V	DO40801	UCEC	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1667
p.T11395N	TCGA-AZ-4315	COAD	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.7055
p.T11395N	DO8842	COAD	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.7055
p.A11107T	TCGA-AZ-4315	COAD	TCGA	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7139
p.A11107T	DO8842	COAD	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7139
p.A11107T	SIDM01424	B-Lymphoblastic Leukemia	GDSC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7139
p.A11107T	ACH-000782	Leukemia	CCLE	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7139
p.A11107T	ACH-001735	Leukemia	CCLE	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7139
p.N8324H	TCGA-AZ-4315	COAD	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.25
p.N8324H	DO8842	COAD	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.25
p.P6588H	TCGA-AZ-4315	COAD	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.0833
p.P6588H	DO8842	COAD	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.0833
p.V4020A	TCGA-AZ-4315	COAD	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6936
p.V4020A	DO8842	COAD	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6936
p.T8990I	TCGA-B0-4698	KIRC	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation blocking phosphorylation signal	0.5
p.T8990I	DO20368	KIRC	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation blocking phosphorylation signal	0.5
p.S925I	TCGA-B0-4706	KIRC	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation altering degron motif	0.7341
p.S925I	DO20565	KIRC	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation altering degron motif	0.7341
p.S6766L	TCGA-B0-5095	KIRC	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	TCGA-D3-A8GB	SKCM	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	TCGA-ER-A19F	SKCM	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	DO16335	KIRC	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	DO37679	SKCM	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	DO50280	SKCM	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	SIDM00118	Colorectal Carcinoma	GDSC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.S6766L	ACH-001081	Colon/Colorectal Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1667
p.E11430D	TCGA-B5-A0JY	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.5647
p.E11430D	DO43041	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.5647
p.G1857E	TCGA-B5-A0JY	UCEC	TCGA	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.G1857E	DO220878	MELA	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.G1857E	DO222595	MELA	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.G1857E	DO43041	UCEC	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.G224R	TCGA-B5-A0JY	UCEC	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.G224R	DO43041	UCEC	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.P9741H	TCGA-B5-A11E	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation altering degron motif	0.7694
p.P9741H	TCGA-DU-6392	LGG	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation altering degron motif	0.7694
p.P9741H	DO22237	LGG	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation altering degron motif	0.7694
p.P9741H	DO41644	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation altering degron motif	0.7694
p.R5771K	TCGA-B5-A11E	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771K	DO41644	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.A4662T	TCGA-B5-A11E	UCEC	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.0556
p.A4662T	DO41644	UCEC	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.0556
p.V11404A	TCGA-B5-A11H	UCEC	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.3056
p.V11404A	DO42825	UCEC	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.3056
p.R5086C	TCGA-B5-A11J	UCEC	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.R5086C	DO43698	UCEC	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.25
p.S2078C	TCGA-B5-A11R	UCEC	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1944
p.S2078C	DO43787	UCEC	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1944
p.S8189P	TCGA-B5-A11S	UCEC	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0833
p.S8189P	DO41895	UCEC	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0833
p.T11536S	TCGA-B5-A1MR	UCEC	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.6005
p.T11536S	DO41758	UCEC	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.6005
p.D9262Y	TCGA-B5-A1MR	UCEC	TCGA	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.2222
p.D9262Y	TCGA-B5-A1MR	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.25
p.D9262Y	DO41758	UCEC	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.2222
p.D9262Y	DO41758	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.25
p.L2331I	TCGA-B5-A1MR	UCEC	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.2222
p.L2331I	DO41758	UCEC	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.2222
p.E2107G	TCGA-B5-A1MR	UCEC	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1111
p.E2107G	DO41758	UCEC	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1111
p.G11314S	TCGA-B5-A1MX	UCEC	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.0833
p.G11314S	TCGA-B5-A1MX	UCEC	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.2222
p.G11314S	DO41999	UCEC	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.0833
p.G11314S	DO41999	UCEC	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.2222
p.E11583D	TCGA-B5-A3FA	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.5647
p.E11583D	DO52402	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.5647
p.T10953I	TCGA-B5-A3FA	UCEC	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.T10953I	DO52402	UCEC	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1667
p.S8326N	TCGA-B5-A3FA	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1944
p.S8326N	DO52402	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1944
p.I4646V	TCGA-B5-A3FA	UCEC	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation altering degron motif	0.5965
p.I4646V	DO52402	UCEC	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation altering degron motif	0.5965
p.S7290F	TCGA-B5-A3FC	UCEC	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	TCGA-EB-A41A	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	TCGA-EE-A2MJ	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	DO220899	MELA	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	DO37429	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	DO38099	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.S7290F	DO41871	UCEC	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.25
p.Q5356R	TCGA-B5-A3FC	UCEC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.25
p.Q5356R	DO41871	UCEC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.25
p.A4923V	TCGA-B5-A3FC	UCEC	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.0833
p.A4923V	DO41871	UCEC	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.0833
p.M1664V	TCGA-B5-A3FC	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.2778
p.M1664V	DO41871	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.2778
p.T7529S	TCGA-B6-A0RE	BRCA	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.2778
p.T7529S	DO3482	BRCA	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.2778
p.T10399A	TCGA-B7-5816	STAD	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.0556
p.T10399A	DO38599	STAD	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.0556
p.I5471V	TCGA-BA-4076	HNSC	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.25
p.I5471V	DO14502	HNSC	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.25
p.P5148H	TCGA-BA-4078	HNSC	TCGA	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.1389
p.P5148H	DO14173	HNSC	ICGC	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.1389
p.E5813D	TCGA-BA-6869	HNSC	TCGA	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.25
p.E5813D	TCGA-BA-6869	HNSC	TCGA	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1667
p.E5813D	DO14250	HNSC	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.25
p.E5813D	DO14250	HNSC	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1667
p.S9329G	TCGA-BA-A4IF	HNSC	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.6993
p.S9329G	DO49043	HNSC	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.6993
p.H6296Q	TCGA-BB-7870	HNSC	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.0556
p.H6296Q	DO14378	HNSC	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.0556
p.P11354S	TCGA-BF-A1PV	SKCM	TCGA	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1111
p.P11354S	DO220872	MELA	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1111
p.P11354S	DO47309	SKCM	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1111
p.P1161S	TCGA-BF-A1PX	SKCM	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.6752
p.P1161S	DO51236	SKCM	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.6752
p.G12009V	TCGA-BF-A1PZ	SKCM	TCGA	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.2778
p.G12009V	DO50279	SKCM	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.2778
p.G11590W	TCGA-BF-A1PZ	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2222
p.G11590W	DO50279	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2222
p.P4772L	TCGA-BF-A1PZ	SKCM	TCGA	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.P4772L	DO50279	SKCM	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.S11709F	TCGA-BF-A1Q0	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	TCGA-D3-A2JN	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO220856	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO220891	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO222521	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO222653	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO222868	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO47374	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S11709F	DO47590	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation blocking phosphorylation signal	0.5
p.S10847L	TCGA-BF-A3DL	SKCM	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation blocking phosphorylation signal	0.5833
p.S10847L	DO51238	SKCM	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation blocking phosphorylation signal	0.5833
p.D8060N	TCGA-BF-A5EQ	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.3056
p.D8060N	TCGA-QK-A6VC	HNSC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.3056
p.D8060N	DO219056	HNSC	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.3056
p.D8060N	DO219452	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.3056
p.P10836S	TCGA-BF-A5ES	SKCM	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation altering degron motif	0.6752
p.P10836S	DO219456	SKCM	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation altering degron motif	0.6752
p.D4019N	TCGA-BF-AAOU	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.3056
p.D4019N	DO219460	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.3056
p.A1648T	TCGA-BF-AAOU	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.A1648T	DO219460	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.A1648T	SIDM01608	Endometrial Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.A1648T	ACH-000990	Endometrial/Uterine Cancer	CCLE	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.T150I	TCGA-BF-AAOX	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	151:155	Mutation blocking phosphorylation signal	0.75
p.T150I	DO223907	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation blocking phosphorylation signal	0.75
p.E8152K	TCGA-BF-AAP0	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.E8152K	DO219462	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.P445S	TCGA-BF-AAP0	SKCM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.P445S	TCGA-D3-A5GO	SKCM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.P445S	DO47419	SKCM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.P445S	DO219462	SKCM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.G2884R	TCGA-BF-AAP1	SKCM	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1389
p.G2884R	DO219464	SKCM	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1389
p.R885M	TCGA-BF-AAP1	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.3056
p.R885M	DO219464	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.3056
p.S6054F	TCGA-BF-AAP2	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.6871
p.S6054F	DO219466	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.6871
p.G11040R	TCGA-BF-AAP4	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11040R	DO219468	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11040R	SIDM00188	Kidney Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11040R	ACH-002139	Kidney Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11040R	HA7-RCC	kidney	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.P2471L	TCGA-BF-AAP7	SKCM	TCGA	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.1111
p.P2471L	DO219472	SKCM	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.1111
p.S356P	TCGA-BG-A0LX	UCEC	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6752
p.S356P	DO41919	UCEC	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6752
p.V11631A	TCGA-BG-A222	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.0833
p.V11631A	DO42977	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.0833
p.T11432I	TCGA-BG-A222	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7078
p.T11432I	DO42977	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7078
p.T9009S	TCGA-BG-A222	UCEC	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.2778
p.T9009S	DO42977	UCEC	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.2778
p.S6608L	TCGA-BH-A0AW	BRCA	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	TCGA-FW-A3R5	SKCM	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	TCGA-QB-A6FS	SKCM	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	TCGA-X8-AAAR	ESCA	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	DO5005	BRCA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	DO233665	GACA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	DO222662	MELA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	DO37406	SKCM	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.S6608L	DO48654	SKCM	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1389
p.T3535A	TCGA-BH-A18G	BRCA	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.7139
p.T3535A	DO3686	BRCA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.7139
p.D4025N	TCGA-BH-A18P	BRCA	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6932
p.D4025N	DO3346	BRCA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6932
p.S8053F	TCGA-BH-A1FH	BRCA	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1111
p.S8053F	DO3946	BRCA	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1111
p.M6880K	TCGA-BP-4964	KIRC	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2778
p.M6880K	DO16263	KIRC	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2778
p.S3732T	TCGA-BP-4993	KIRC	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1944
p.S3732T	DO20171	KIRC	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1944
p.T8188I	TCGA-BP-5004	KIRC	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1111
p.T8188I	DO17353	KIRC	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1111
p.E2896D	TCGA-BQ-5876	KIRP	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.5647
p.E2896D	DO20759	KIRP	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.5647
p.D1437N	TCGA-BQ-5878	KIRP	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.1111
p.D1437N	DO20823	KIRP	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.1111
p.T5764P	TCGA-BR-4184	STAD	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation altering degron motif	0.7031
p.T5764P	TCGA-NQ-A57I	MESO	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation altering degron motif	0.7031
p.T5764P	DO38328	STAD	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation altering degron motif	0.7031
p.T1494A	TCGA-BR-4201	STAD	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.7139
p.T1494A	DO38707	STAD	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.7139
p.P1491L	TCGA-BR-4257	STAD	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6471
p.P1491L	DO38683	STAD	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6471
p.S688P	TCGA-BR-4279	STAD	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1111
p.S688P	DO38811	STAD	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1111
p.T10182I	TCGA-BR-4361	STAD	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation altering degron motif	0.7078
p.T10182I	DO38887	STAD	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation altering degron motif	0.7078
p.T13161A	TCGA-BR-4366	STAD	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2778
p.T13161A	DO234413	ESAD	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2778
p.T13161A	DO38419	STAD	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2778
p.G12815V	TCGA-BR-6452	STAD	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1111
p.G12815V	DO38404	STAD	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1111
p.V12344D	TCGA-BR-6452	STAD	TCGA	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.V12344D	DO38404	STAD	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.K5149E	TCGA-BR-6452	STAD	TCGA	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation substituting flanking lysine	0.2778
p.K5149E	DO38404	STAD	ICGC	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation substituting flanking lysine	0.2778
p.K5240T	TCGA-BR-6454	STAD	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation substituting flanking lysine	0.1944
p.K5240T	DO38595	STAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation substituting flanking lysine	0.1944
p.E11386D	TCGA-BR-6457	STAD	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.0833
p.E11386D	DO38759	STAD	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.0833
p.E11386D	SIDM00890	Melanoma	GDSC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.0833
p.E11386D	ACH-000580	Skin Cancer	CCLE	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.0833
p.E11386D	C32	skin	COSMIC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.0833
p.T9486P	TCGA-BR-6458	STAD	TCGA	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation altering degron motif	0.7031
p.T9486P	DO38296	STAD	ICGC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation altering degron motif	0.7031
p.K5232T	TCGA-BR-6563	STAD	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.K5232T	DO234413	ESAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.K5232T	DO38364	STAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.S2099C	TCGA-BR-7704	STAD	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation altering degron motif	0.7541
p.S2099C	DO38360	STAD	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation altering degron motif	0.7541
p.T8780K	TCGA-BR-7716	STAD	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7306
p.T8780K	DO38675	STAD	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7306
p.A11079V	TCGA-BR-7958	STAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.3056
p.A11079V	TCGA-BR-7958	STAD	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1667
p.A11079V	DO38344	STAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.3056
p.A11079V	DO38344	STAD	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1667
p.F1768L	TCGA-BR-7959	STAD	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.1389
p.F1768L	DO38408	STAD	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.1389
p.T38N	TCGA-BR-8384	STAD	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.25
p.T38N	DO47749	STAD	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.25
p.S12977F	TCGA-BR-8484	STAD	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.25
p.S12977F	TCGA-BR-8484	STAD	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2778
p.S12977F	TCGA-BR-8484	STAD	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.S12977F	DO222837	MELA	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.25
p.S12977F	DO222837	MELA	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2778
p.S12977F	DO222837	MELA	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.S12977F	DO48024	STAD	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.25
p.S12977F	DO48024	STAD	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2778
p.S12977F	DO48024	STAD	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.Q3989H	TCGA-BR-8485	STAD	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.2222
p.Q3989H	DO47823	STAD	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.2222
p.R13599Q	TCGA-BR-8487	STAD	TCGA	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.25
p.R13599Q	DO47867	STAD	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.25
p.R13599Q	SIDM01233	Colorectal Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.25
p.R13599Q	ACH-000009	Colon/Colorectal Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.25
p.R13599Q	C2BBe1	large intestine	COSMIC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.25
p.T12820P	TCGA-BR-8680	STAD	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.25
p.T12820P	TCGA-BR-8680	STAD	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1111
p.T12820P	DO47769	STAD	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.25
p.T12820P	DO47769	STAD	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1111
p.E11949D	TCGA-BR-8680	STAD	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.3056
p.E11949D	DO47769	STAD	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.3056
p.E8152D	TCGA-BR-8680	STAD	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.E8152D	TCGA-D7-6528	STAD	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.E8152D	DO38547	STAD	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.E8152D	DO47769	STAD	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1667
p.R12975Q	TCGA-BR-A4CQ	STAD	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975Q	TCGA-BR-A4CQ	STAD	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975Q	TCGA-BR-A4CQ	STAD	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.R12975Q	DO47861	STAD	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.R12975Q	DO47861	STAD	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.2222
p.R12975Q	DO47861	STAD	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.S11524C	TCGA-BS-A0TI	UCEC	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1111
p.S11524C	DO41608	UCEC	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1111
p.R5771I	TCGA-BS-A0UF	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	DO41488	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	SIDM00747	Non-Small Cell Lung Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	SIDM00118	Colorectal Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	ACH-000744	Lung Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	ACH-001081	Colon/Colorectal Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	HCC2998	large intestine	COSMIC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.R5771I	NCI-H1623	lung	COSMIC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1389
p.P4941T	TCGA-BS-A0UF	UCEC	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.P4941T	DO41488	UCEC	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.T10030A	TCGA-BS-A0UJ	UCEC	TCGA	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation altering degron motif	0.7139
p.T10030A	DO42745	UCEC	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation altering degron motif	0.7139
p.S10659L	TCGA-BS-A0UV	UCEC	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	TCGA-D3-A2JP	SKCM	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	TCGA-EE-A2MS	SKCM	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	TCGA-G4-6302	COAD	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	TCGA-GN-A4U4	SKCM	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO8778	COAD	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO220861	MELA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO222402	MELA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO37567	SKCM	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO47407	SKCM	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO51256	SKCM	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.S10659L	DO42793	UCEC	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.2778
p.T2902N	TCGA-BS-A0UV	UCEC	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.2778
p.T2902N	TCGA-BS-A0UV	UCEC	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1944
p.T2902N	DO42793	UCEC	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.2778
p.T2902N	DO42793	UCEC	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1944
p.L2407F	TCGA-BS-A0UV	UCEC	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1111
p.L2407F	DO42793	UCEC	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1111
p.T3015I	TCGA-BS-A0V7	UCEC	TCGA	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.T3015I	DO42392	UCEC	ICGC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.E12016K	TCGA-BT-A0S7	BLCA	TCGA	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.0833
p.E12016K	DO504	BLCA	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.0833
p.L10991V	TCGA-BT-A20U	BLCA	TCGA	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.1667
p.L10991V	DO538	BLCA	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.1667
p.S5224T	TCGA-BT-A3PH	BLCA	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5224T	DO856	BLCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.V12049L	TCGA-BW-A5NO	LIHC	TCGA	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation altering degron motif	0.5654
p.V12049L	DO52171	LIHC	ICGC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation altering degron motif	0.5654
p.P8910S	TCGA-C5-A1MK	CESC	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.2778
p.P8910S	DO6290	CESC	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.2778
p.A6887E	TCGA-C5-A2LT	CESC	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.3056
p.A6887E	DO49880	CESC	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.3056
p.A6887E	DO229034	LICA	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.3056
p.A6887E	ACH-002055	Lymphoma	CCLE	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.3056
p.H9827Y	TCGA-C5-A3HF	CESC	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1667
p.H9827Y	DO49015	CESC	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1667
p.S8175L	TCGA-C5-A3HF	CESC	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.S8175L	TCGA-Z2-A8RT	SKCM	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.S8175L	DO49015	CESC	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.S8175L	DO51301	SKCM	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.S8070F	TCGA-C5-A7X5	CESC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1944
p.S8070F	DO49894	CESC	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1944
p.P5644S	TCGA-C5-A8XH	CESC	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.6752
p.P5644S	DO49898	CESC	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.6752
p.G1152D	TCGA-CA-5256	COAD	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.0833
p.G1152D	DO10526	COAD	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.0833
p.K10462Q	TCGA-CA-6717	COAD	TCGA	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation substituting flanking lysine	0.2778
p.K10462Q	DO8264	COAD	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation substituting flanking lysine	0.2778
p.F4645V	TCGA-CA-6717	COAD	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.F4645V	DO8264	COAD	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.3056
p.K515Q	TCGA-CA-6717	COAD	TCGA	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation substituting flanking lysine	0.3611
p.K515Q	DO8264	COAD	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation substituting flanking lysine	0.3611
p.S11173Y	TCGA-CA-6718	COAD	TCGA	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1111
p.S11173Y	TCGA-CA-6718	COAD	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2222
p.S11173Y	DO7801	COAD	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1111
p.S11173Y	DO7801	COAD	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2222
p.F10842C	TCGA-CA-6718	COAD	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2778
p.F10842C	DO7801	COAD	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2778
p.S8085Y	TCGA-CA-6718	COAD	TCGA	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.25
p.S8085Y	DO7801	COAD	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.25
p.S7745R	TCGA-CA-6718	COAD	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.25
p.S7745R	DO7801	COAD	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.25
p.S1083F	TCGA-CA-6718	COAD	TCGA	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1083F	DO7801	COAD	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1083F	SIDM00680	Colorectal Carcinoma	GDSC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1083F	ACH-000957	Colon/Colorectal Cancer	CCLE	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1083F	LS-180	large intestine	COSMIC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.T12371S	TCGA-CC-A1HT	LIHC	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1111
p.T12371S	DO23028	LIHC	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1111
p.T11103N	TCGA-CC-A1HT	LIHC	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.7055
p.T11103N	DO23028	LIHC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.7055
p.T11103P	TCGA-CC-A1HT	LIHC	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.7031
p.T11103P	DO23028	LIHC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.7031
p.I11172V	TCGA-CC-A7IH	LIHC	TCGA	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1389
p.I11172V	TCGA-CC-A7IH	LIHC	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1944
p.I11172V	DO52181	LIHC	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1389
p.I11172V	DO52181	LIHC	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1944
p.P4479T	TCGA-CC-A8HS	LIHC	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0833
p.P4479T	DO52186	LIHC	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0833
p.P9808L	TCGA-CC-A8HT	LIHC	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0833
p.P9808L	DO52187	LIHC	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0833
p.K544E	TCGA-CD-5801	STAD	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation substituting flanking lysine	0.3056
p.K544E	DO38563	STAD	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation substituting flanking lysine	0.3056
p.R13755Q	TCGA-CD-8531	STAD	TCGA	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755Q	DO234363	ESAD	ICGC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755Q	DO47877	STAD	ICGC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755Q	SIDM01335	Kidney Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755Q	ACH-000513	Kidney Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.P8223S	TCGA-CD-8536	STAD	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.0833
p.P8223S	DO218874	SKCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.0833
p.P8223S	DO47827	STAD	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.0833
p.S688L	TCGA-CF-A27C	BLCA	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1111
p.S688L	DO828	BLCA	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1111
p.M10174V	TCGA-CG-4306	STAD	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.1389
p.M10174V	DO38567	STAD	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.1389
p.L12991R	TCGA-CG-5724	STAD	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.2222
p.L12991R	TCGA-CG-5724	STAD	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1111
p.L12991R	TCGA-CG-5724	STAD	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.25
p.L12991R	DO38847	STAD	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.2222
p.L12991R	DO38847	STAD	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1111
p.L12991R	DO38847	STAD	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.25
p.R10555M	TCGA-CG-5728	STAD	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2222
p.R10555M	TCGA-DD-AACK	LIHC	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2222
p.R10555M	DO52207	LIHC	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2222
p.R10555M	DO38619	STAD	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2222
p.H2723R	TCGA-CG-5728	STAD	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.3056
p.H2723R	DO38619	STAD	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.3056
p.P10646T	TCGA-CJ-5671	KIRC	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1667
p.P10646T	DO16560	KIRC	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1667
p.S1493P	TCGA-CJ-5682	KIRC	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.5641
p.S1493P	DO18056	KIRC	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.5641
p.P12530S	TCGA-CK-4951	COAD	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.0833
p.P12530S	TCGA-D3-A1Q6	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.0833
p.P12530S	DO10582	COAD	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.0833
p.P12530S	DO37450	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.0833
p.P7110H	TCGA-CM-6165	COAD	TCGA	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7694
p.P7110H	DO9900	COAD	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7694
p.S10342F	TCGA-CN-4736	HNSC	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation blocking phosphorylation signal	0.5833
p.S10342F	DO15118	HNSC	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation blocking phosphorylation signal	0.5833
p.R8155M	TCGA-CN-4739	HNSC	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.25
p.R8155M	DO14478	HNSC	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.25
p.T8204A	TCGA-CN-A497	HNSC	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.25
p.T8204A	DO218992	HNSC	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.25
p.P12980H	TCGA-CQ-5330	HNSC	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7694
p.P12980H	TCGA-CQ-5330	HNSC	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation altering degron motif	0.6583
p.P12980H	DO16037	HNSC	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7694
p.P12980H	DO16037	HNSC	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation altering degron motif	0.6583
p.F12972L	TCGA-CQ-A4CD	HNSC	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.F12972L	TCGA-CQ-A4CD	HNSC	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1389
p.F12972L	DO49038	HNSC	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.F12972L	DO49038	HNSC	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1389
p.L7124F	TCGA-CR-6472	HNSC	TCGA	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.0556
p.L7124F	DO15870	HNSC	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.0556
p.L1865F	TCGA-CR-6473	HNSC	TCGA	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.0556
p.L1865F	DO14228	HNSC	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.0556
p.D6324N	TCGA-CR-7371	HNSC	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.0833
p.D6324N	DO15454	HNSC	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.0833
p.V7696M	TCGA-CR-7398	HNSC	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.V7696M	TCGA-G9-6494	PRAD	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.V7696M	TCGA-VM-A8CE	LGG	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.V7696M	DO14782	HNSC	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.V7696M	DO50252	LGG	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.V7696M	DO36315	PRAD	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.G10816S	TCGA-CR-7399	HNSC	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.0556
p.G10816S	DO15759	HNSC	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.0556
p.T9263R	TCGA-CR-7402	HNSC	TCGA	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.25
p.T9263R	TCGA-CR-7402	HNSC	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.2778
p.T9263R	DO15727	HNSC	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.25
p.T9263R	DO15727	HNSC	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.2778
p.T8322N	TCGA-CV-5432	HNSC	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.3056
p.T8322N	DO14343	HNSC	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.3056
p.H9457R	TCGA-CV-5978	HNSC	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.2778
p.H9457R	DO16023	HNSC	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.2778
p.V8158F	TCGA-CV-5978	HNSC	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7068
p.V8158F	DO16023	HNSC	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7068
p.T6884I	TCGA-CV-6938	HNSC	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation altering degron motif	0.7078
p.T6884I	DO14462	HNSC	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation altering degron motif	0.7078
p.S11056I	TCGA-CV-7104	HNSC	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.S11056I	DO14798	HNSC	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.T12993S	TCGA-CV-7248	HNSC	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1667
p.T12993S	TCGA-CV-7248	HNSC	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0556
p.T12993S	TCGA-CV-7248	HNSC	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1944
p.T12993S	DO14806	HNSC	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1667
p.T12993S	DO14806	HNSC	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0556
p.T12993S	DO14806	HNSC	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1944
p.S12369L	TCGA-CV-7406	HNSC	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation blocking phosphorylation signal	0.6111
p.S12369L	DO15422	HNSC	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation blocking phosphorylation signal	0.6111
p.S914F	TCGA-CV-7568	HNSC	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.1111
p.S914F	DO14160	HNSC	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.1111
p.V4773I	TCGA-CV-A468	HNSC	TCGA	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.V4773I	DO52070	HNSC	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.H8051Y	TCGA-CV-A6K2	HNSC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0556
p.H8051Y	DO52079	HNSC	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0556
p.H8051Y	DO229456	SKCA	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.0556
p.P11362L	TCGA-CX-7086	HNSC	TCGA	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.6471
p.P11362L	DO15046	HNSC	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.6471
p.D5616N	TCGA-D1-A103	UCEC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2222
p.D5616N	DO42312	UCEC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2222
p.R4018K	TCGA-D1-A103	UCEC	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.R4018K	DO42312	UCEC	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.S3566N	TCGA-D1-A103	UCEC	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.5958
p.S3566N	DO42312	UCEC	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.5958
p.L1835R	TCGA-D1-A16X	UCEC	TCGA	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.25
p.L1835R	TCGA-D1-A16X	UCEC	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0833
p.L1835R	DO41799	UCEC	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.25
p.L1835R	DO41799	UCEC	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0833
p.A4787T	TCGA-D1-A16Y	UCEC	TCGA	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.A4787T	DO41524	UCEC	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.A4787T	SIDM00433	T-Lymphoblastic Leukemia	GDSC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.A4787T	ACH-000795	Leukemia	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.A4787T	MOLT-13	haematopoietic and lymphoid tissue	COSMIC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.V11520A	TCGA-D1-A177	UCEC	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.0556
p.V11520A	DO42528	UCEC	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.0556
p.S2507N	TCGA-D1-A17H	UCEC	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.3056
p.S2507N	DO41847	UCEC	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.3056
p.S9729Y	TCGA-D1-A17Q	UCEC	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1944
p.S9729Y	DO41903	UCEC	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1944
p.R11106S	TCGA-D3-A1Q3	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.25
p.R11106S	TCGA-D3-A1Q3	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.3056
p.R11106S	DO47509	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.25
p.R11106S	DO47509	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.3056
p.R10996M	TCGA-D3-A1Q3	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.3056
p.R10996M	DO47509	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.3056
p.G6480R	TCGA-D3-A1Q4	SKCM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.G6480R	DO220881	MELA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.G6480R	DO222702	MELA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.G6480R	DO47631	SKCM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.P706S	TCGA-D3-A1Q5	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.P706S	DO37827	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.E3891K	TCGA-D3-A1QA	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.1667
p.E3891K	DO47469	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.1667
p.G3303E	TCGA-D3-A1QB	SKCM	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.2778
p.G3303E	DO47573	SKCM	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.2778
p.R1668K	TCGA-D3-A2JA	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1667
p.R1668K	DO47652	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1667
p.S2498Y	TCGA-D3-A2JC	SKCM	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.0556
p.S2498Y	DO229025	LICA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.0556
p.S2498Y	DO47578	SKCM	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.0556
p.P165H	TCGA-D3-A2JD	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.P165H	DO37543	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.L11869F	TCGA-D3-A2JF	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.0556
p.L11869F	DO38153	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.0556
p.S7742L	TCGA-D3-A2JF	SKCM	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.7667
p.S7742L	DO38153	SKCM	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.7667
p.G693E	TCGA-D3-A2JF	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.G693E	TCGA-D3-A8GC	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.G693E	TCGA-D3-A8GQ	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.G693E	DO50281	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.G693E	DO51246	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.G693E	DO38153	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.S10188F	TCGA-D3-A2JO	SKCM	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2778
p.S10188F	DO47619	SKCM	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2778
p.E6506K	TCGA-D3-A2JO	SKCM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0556
p.E6506K	DO220903	MELA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0556
p.E6506K	DO220902	MELA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0556
p.E6506K	DO47619	SKCM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0556
p.L5634M	TCGA-D3-A3C1	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1111
p.L5634M	TCGA-D3-A3C1	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0556
p.L5634M	DO47323	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1111
p.L5634M	DO47323	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0556
p.S12831F	TCGA-D3-A3C3	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7982
p.S12831F	DO47667	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation altering degron motif	0.7982
p.S11896F	TCGA-D3-A3C7	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.5556
p.S11896F	TCGA-EE-A2GP	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.5556
p.S11896F	DO37422	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.5556
p.S11896F	DO47569	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.5556
p.G10929E	TCGA-D3-A3C7	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.G10929E	DO47569	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.P10190S	TCGA-D3-A3C7	SKCM	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.P10190S	TCGA-DA-A95Y	SKCM	TCGA	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.P10190S	DO47569	SKCM	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.P10190S	DO223908	SKCM	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.2222
p.E9531K	TCGA-D3-A3C7	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.E9531K	TCGA-YG-AA3N	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.E9531K	DO47569	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.E9531K	DO51298	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.E9531K	SIDM00933	Breast Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.E9531K	SIDM00875	Breast Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2222
p.P896Q	TCGA-D3-A3CB	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.7035
p.P896Q	DO47386	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.7035
p.T11892I	TCGA-D3-A3ML	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.0833
p.T11892I	TCGA-D3-A3ML	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.2222
p.T11892I	DO47413	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.0833
p.T11892I	DO47413	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.2222
p.P11313L	TCGA-D3-A3ML	SKCM	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.P11313L	TCGA-D3-A3ML	SKCM	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.25
p.P11313L	DO47413	SKCM	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.P11313L	DO47413	SKCM	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.25
p.E3109K	TCGA-D3-A3MR	SKCM	TCGA	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2222
p.E3109K	TCGA-W3-A825	SKCM	TCGA	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2222
p.E3109K	DO47256	SKCM	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2222
p.E3109K	DO51272	SKCM	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2222
p.P11765S	TCGA-D3-A51G	SKCM	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.2222
p.P11765S	TCGA-D3-A51G	SKCM	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.P11765S	TCGA-D3-A8GC	SKCM	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.2222
p.P11765S	TCGA-D3-A8GC	SKCM	TCGA	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.P11765S	DO50281	SKCM	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.2222
p.P11765S	DO50281	SKCM	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.P11765S	DO47700	SKCM	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.2222
p.P11765S	DO47700	SKCM	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.P7701L	TCGA-D3-A51G	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7582
p.P7701L	DO222647	MELA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7582
p.P7701L	DO47700	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7582
p.H3714Y	TCGA-D3-A51T	SKCM	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.H3714Y	DO229470	SKCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.H3714Y	DO218861	SKCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.H3714Y	DO47389	SKCM	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1389
p.S11312L	TCGA-D3-A5GL	SKCM	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1389
p.S11312L	TCGA-D3-A5GL	SKCM	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.2778
p.S11312L	DO47430	SKCM	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1389
p.S11312L	DO47430	SKCM	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.2778
p.G6480E	TCGA-D3-A5GN	SKCM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.G6480E	DO47317	SKCM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.S5646F	TCGA-D3-A5GN	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	TCGA-EE-A29A	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	TCGA-FW-A3R5	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	TCGA-OD-A75X	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO228011	SKCA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO229453	SKCA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO37416	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO37406	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO47317	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.S5646F	DO48601	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation altering degron motif	0.7982
p.M543I	TCGA-D3-A5GN	SKCM	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1667
p.M543I	DO47317	SKCM	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1667
p.S8766F	TCGA-D3-A5GO	SKCM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	TCGA-D3-A5GO	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S8766F	TCGA-YD-A89C	SKCM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	TCGA-YD-A89C	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S8766F	DO220909	MELA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	DO220909	MELA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S8766F	DO229494	SKCA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	DO229494	SKCA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S8766F	DO47419	SKCM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	DO47419	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S8766F	DO219501	SKCM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1389
p.S8766F	DO219501	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0556
p.S7703F	TCGA-D3-A5GO	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7982
p.S7703F	TCGA-GN-A4U4	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7982
p.S7703F	DO47419	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7982
p.S7703F	DO51256	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation altering degron motif	0.7982
p.R8155K	TCGA-D3-A5GU	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.25
p.R8155K	DO47584	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.25
p.E4868K	TCGA-D3-A5GU	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2778
p.E4868K	TCGA-EE-A3AE	SKCM	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2778
p.E4868K	DO37802	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2778
p.E4868K	DO47584	SKCM	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2778
p.M4636I	TCGA-D3-A8GC	SKCM	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.0556
p.M4636I	DO50281	SKCM	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.0556
p.S3888F	TCGA-D3-A8GC	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0833
p.S3888F	TCGA-EE-A29M	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0833
p.S3888F	DO220877	MELA	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0833
p.S3888F	DO37404	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0833
p.S3888F	DO50281	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.0833
p.P11695L	TCGA-D3-A8GI	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7582
p.P11695L	DO50284	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7582
p.S7098F	TCGA-D3-A8GI	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.1944
p.S7098F	DO50284	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.1944
p.S6589F	TCGA-D3-A8GI	SKCM	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1111
p.S6589F	DO218840	SKCA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1111
p.S6589F	DO50284	SKCM	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.1111
p.G3467R	TCGA-D3-A8GI	SKCM	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.G3467R	DO50284	SKCM	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.E6314K	TCGA-D3-A8GL	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	TCGA-EE-A2MR	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	TCGA-FS-A1ZK	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	TCGA-W3-AA1V	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	DO37819	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	DO37474	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	DO50287	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.E6314K	DO51276	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.P11503S	TCGA-D3-A8GM	SKCM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.6752
p.P11503S	TCGA-GF-A6C9	SKCM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.6752
p.P11503S	DO50288	SKCM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.6752
p.P11503S	DO51254	SKCM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.6752
p.S7973F	TCGA-D3-A8GM	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S7973F	TCGA-FR-A7U9	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S7973F	DO48546	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S7973F	DO50288	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S5641F	TCGA-D3-A8GM	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.25
p.S5641F	DO50288	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.25
p.P10772L	TCGA-D3-A8GO	SKCM	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.2778
p.P10772L	DO51242	SKCM	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.2778
p.E10689K	TCGA-D3-A8GQ	SKCM	TCGA	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation altering degron motif	0.591
p.E10689K	DO51246	SKCM	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation altering degron motif	0.591
p.P1490L	TCGA-D3-A8GQ	SKCM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.P1490L	TCGA-GN-A8LK	SKCM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.P1490L	DO51259	SKCM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.P1490L	DO51246	SKCM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.S9161F	TCGA-D3-A8GR	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation altering degron motif	0.7982
p.S9161F	DO51247	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation altering degron motif	0.7982
p.P5318S	TCGA-D3-A8GR	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1667
p.P5318S	DO51247	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1667
p.V3992A	TCGA-D3-A8GR	SKCM	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1389
p.V3992A	DO51247	SKCM	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1389
p.E10915K	TCGA-D3-A8GV	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1667
p.E10915K	DO219477	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1667
p.H9807Y	TCGA-D3-A8GV	SKCM	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	TCGA-D9-A3Z1	SKCM	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	TCGA-EE-A29E	SKCM	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	DO218863	SKCA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	DO37831	SKCM	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	DO38105	SKCM	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807Y	DO219477	SKCM	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.S2078Y	TCGA-D5-6537	COAD	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1944
p.S2078Y	DO9530	COAD	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1944
p.S11303Y	TCGA-D5-6898	COAD	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation altering degron motif	0.712
p.S11303Y	DO10028	COAD	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation altering degron motif	0.712
p.A2464T	TCGA-D5-6928	COAD	TCGA	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.A2464T	DO7776	COAD	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.N11594H	TCGA-D5-6932	COAD	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.N11594H	DO9378	COAD	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1111
p.S8190G	TCGA-D7-6818	STAD	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0556
p.S8190G	DO38262	STAD	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0556
p.M8311V	TCGA-D7-A6EY	STAD	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1667
p.M8311V	DO50118	STAD	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1667
p.P11964L	TCGA-D9-A4Z3	SKCM	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1111
p.P11964L	DO222498	MELA	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1111
p.P11964L	DO47555	SKCM	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1111
p.P10922S	TCGA-D9-A4Z3	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.5641
p.P10922S	DO47555	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.5641
p.S1172L	TCGA-D9-A6EA	SKCM	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1667
p.S1172L	DO50290	SKCM	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1667
p.N11263I	TCGA-D9-A6EC	SKCM	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.0556
p.N11263I	DO50291	SKCM	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.0556
p.E9524K	TCGA-D9-A6EC	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation altering degron motif	0.591
p.E9524K	DO50291	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation altering degron motif	0.591
p.S5633F	TCGA-D9-A6EC	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	TCGA-EE-A2GR	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	TCGA-QB-AA9O	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO220852	MELA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO222536	MELA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO222753	MELA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO50291	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO37996	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	DO51267	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	SIDM01175	Other Sarcomas	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	SIDM00149	Melanoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	ACH-000750	Skin Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	ACH-002309	Sarcoma	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	SW684	soft tissue	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5633F	LOXIMVI	skin	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.S5234F	TCGA-D9-A6EC	SKCM	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	TCGA-EE-A29D	SKCM	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	TCGA-W3-AA1Q	SKCM	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	TCGA-YD-A89C	SKCM	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO220895	MELA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO222567	MELA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO50291	SKCM	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO38123	SKCM	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO219487	SKCM	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.S5234F	DO219501	SKCM	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.25
p.T4608I	TCGA-D9-A6EC	SKCM	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.3056
p.T4608I	DO50291	SKCM	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.3056
p.L2R	TCGA-D9-A6EC	SKCM	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation substituting flanking lysine	0.2778
p.L2R	DO50291	SKCM	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation substituting flanking lysine	0.2778
p.S1655F	TCGA-DA-A1HY	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.25
p.S1655F	DO37409	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.25
p.H2077Y	TCGA-DA-A1I4	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1667
p.H2077Y	DO37655	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1667
p.P2729S	TCGA-DA-A1IC	SKCM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.3056
p.P2729S	DO37430	SKCM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.3056
p.P4943L	TCGA-DA-A3F5	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1389
p.P4943L	DO37435	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1389
p.T3122A	TCGA-DA-A3F5	SKCM	TCGA	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.T3122A	DO37435	SKCM	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.P899L	TCGA-DA-A3F8	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.P899L	DO37418	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.S2728F	TCGA-DA-A960	SKCM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7982
p.S2728F	DO219482	SKCM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7982
p.S2728F	SIDM00284	Melanoma	GDSC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7982
p.S2728F	ACH-000805	Skin Cancer	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7982
p.S2728F	COLO-679	skin	COSMIC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7982
p.G36R	TCGA-DA-A960	SKCM	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.G36R	DO219482	SKCM	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.T1506I	TCGA-DD-A39Z	LIHC	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.1111
p.T1506I	DO44954	LIHC	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.1111
p.S10334F	TCGA-DD-A3A9	LIHC	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10334F	TCGA-EE-A2MR	SKCM	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10334F	TCGA-Z2-AA3S	SKCM	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10334F	DO44888	LIHC	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10334F	DO37819	SKCM	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10334F	DO51302	SKCM	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.T10557S	TCGA-DD-AACK	LIHC	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1667
p.T10557S	DO52207	LIHC	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1667
p.D3565V	TCGA-DD-AADO	LIHC	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6674
p.D3565V	DO52241	LIHC	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6674
p.D1759V	TCGA-DD-AADU	LIHC	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6674
p.D1759V	DO52248	LIHC	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6674
p.D10662V	TCGA-DD-AAE7	LIHC	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1944
p.D10662V	DO52262	LIHC	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1944
p.G10408E	TCGA-DD-AAVY	LIHC	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408E	TCGA-FW-A3R5	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408E	DO52284	LIHC	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408E	DO37406	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.E11188D	TCGA-DF-A2KN	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1389
p.E11188D	DO223282	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1389
p.A7478T	TCGA-DF-A2KU	UCEC	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.2222
p.A7478T	DO223286	UCEC	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.2222
p.P5469H	TCGA-DF-A2KU	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.3056
p.P5469H	DO223286	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.3056
p.G3470C	TCGA-DF-A2KU	UCEC	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.0556
p.G3470C	DO223286	UCEC	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.0556
p.S912Y	TCGA-DF-A2KU	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0556
p.S912Y	DO223286	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0556
p.S12821C	TCGA-DG-A2KK	CESC	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.2778
p.S12821C	TCGA-DG-A2KK	CESC	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1389
p.S12821C	DO51595	CESC	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.2778
p.S12821C	DO51595	CESC	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1389
p.V9550A	TCGA-DI-A1BU	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation altering degron motif	0.5825
p.V9550A	DO42023	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation altering degron motif	0.5825
p.T8307A	TCGA-DI-A1BU	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.0556
p.T8307A	DO42023	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.0556
p.D5239N	TCGA-DK-A1A3	BLCA	TCGA	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1111
p.D5239N	DO558	BLCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1111
p.M3561I	TCGA-DK-A1AG	BLCA	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.M3561I	DO822	BLCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.S3002L	TCGA-DK-A3IS	BLCA	TCGA	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.3056
p.S3002L	DO566	BLCA	ICGC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.3056
p.S2920L	TCGA-DK-A3IS	BLCA	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1389
p.S2920L	DO566	BLCA	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1389
p.S10955Y	TCGA-DK-A6AW	BLCA	TCGA	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1111
p.S10955Y	DO48566	BLCA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1111
p.S10539P	TCGA-DK-A6AW	BLCA	TCGA	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation altering degron motif	0.6752
p.S10539P	DO48566	BLCA	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation altering degron motif	0.6752
p.G1653E	TCGA-DK-A6AW	BLCA	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.G1653E	TCGA-RP-A693	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.G1653E	DO48566	BLCA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.G1653E	DO220872	MELA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.G1653E	DO51268	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.A47S	TCGA-DK-AA6U	BLCA	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.2778
p.A47S	DO219008	BLCA	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.2778
p.S10645L	TCGA-DK-AA71	BLCA	TCGA	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1389
p.S10645L	DO219010	BLCA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1389
p.G2509C	TCGA-DM-A1HB	COAD	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation altering degron motif	0.6489
p.Q12819E	TCGA-DR-A0ZM	CESC	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.2222
p.Q12819E	TCGA-DR-A0ZM	CESC	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.0833
p.Q12819E	DO6254	CESC	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.2222
p.Q12819E	DO6254	CESC	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.0833
p.T11760N	TCGA-DU-5854	LGG	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.8166
p.T11760N	DO22466	LGG	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.8166
p.S12670I	TCGA-DU-6392	LGG	TCGA	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation altering degron motif	0.7341
p.S12670I	DO22237	LGG	ICGC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation altering degron motif	0.7341
p.Q6748H	TCGA-DU-6392	LGG	TCGA	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1111
p.Q6748H	DO22237	LGG	ICGC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1111
p.V4480I	TCGA-DU-6392	LGG	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0556
p.V4480I	DO22237	LGG	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0556
p.T694I	TCGA-DU-6392	LGG	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.2778
p.T694I	DO22237	LGG	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.2778
p.P9537T	TCGA-DU-8168	LGG	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.P9537T	DO22367	LGG	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.M1009I	TCGA-DX-A48N	SARC	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.3056
p.M1009I	DO219986	SARC	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.3056
p.T11432R	TCGA-DX-A8BU	SARC	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7876
p.T11432R	TCGA-EE-A2M6	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7876
p.T11432R	DO220065	SARC	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7876
p.T11432R	DO37976	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7876
p.A10774T	TCGA-E6-A1LX	UCEC	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7139
p.A10774T	DO41020	UCEC	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7139
p.A10774T	SIDM00150	Colorectal Carcinoma	GDSC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7139
p.A10774T	ACH-000969	Colon/Colorectal Cancer	CCLE	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7139
p.A10774T	KM12	large intestine	COSMIC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation altering degron motif	0.7139
p.V10530A	TCGA-E6-A1LX	UCEC	TCGA	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.1944
p.V10530A	DO41020	UCEC	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.1944
p.T9263I	TCGA-E6-A1LX	UCEC	TCGA	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.25
p.T9263I	TCGA-E6-A1LX	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.2778
p.T9263I	DO41020	UCEC	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.25
p.T9263I	DO41020	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.2778
p.R8110K	TCGA-E6-A1LX	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1111
p.R8110K	TCGA-EE-A29D	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1111
p.R8110K	DO38123	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1111
p.R8110K	DO41020	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1111
p.S7973Y	TCGA-E6-A1LX	UCEC	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S7973Y	DO41020	UCEC	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.S3993Y	TCGA-E6-A1LX	UCEC	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993Y	DO41020	UCEC	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993Y	SIDM00193	Colorectal Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993Y	ACH-000991	Colon/Colorectal Cancer	CCLE	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993Y	SNU-81	large intestine	COSMIC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.R3905K	TCGA-E6-A1LX	UCEC	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.2222
p.R3905K	DO41020	UCEC	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.2222
p.S2899R	TCGA-E6-A1LX	UCEC	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.7427
p.S2899R	DO234220	ESAD	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.7427
p.S2899R	DO41020	UCEC	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.7427
p.K2521N	TCGA-E6-A1LX	UCEC	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation substituting flanking lysine	0.1944
p.K2521N	DO41020	UCEC	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation substituting flanking lysine	0.1944
p.S1083Y	TCGA-E6-A1LX	UCEC	TCGA	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1083Y	DO41020	UCEC	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.I11623T	TCGA-E6-A1M0	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.3056
p.I11623T	DO43682	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.3056
p.V11296A	TCGA-E6-A1M0	UCEC	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1944
p.V11296A	TCGA-E6-A1M0	UCEC	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.0556
p.V11296A	DO43682	UCEC	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1944
p.V11296A	DO43682	UCEC	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.0556
p.S3227Y	TCGA-E6-A1M0	UCEC	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227Y	TCGA-EI-6917	READ	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227Y	TCGA-EO-A3B0	UCEC	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227Y	DO36881	READ	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227Y	DO219773	UCEC	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227Y	DO43682	UCEC	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.G13163S	TCGA-E7-A541	BLCA	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.G13163S	DO44037	BLCA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.E10115Q	TCGA-E7-A6ME	BLCA	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.2222
p.E10115Q	DO51874	BLCA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.2222
p.Q1744H	TCGA-E7-A7XN	BLCA	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.Q1744H	TCGA-E7-A7XN	BLCA	TCGA	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1667
p.Q1744H	DO51878	BLCA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.Q1744H	DO51878	BLCA	ICGC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1667
p.Q1744H	SIDM00866	Breast Carcinoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.Q1744H	SIDM00866	Breast Carcinoma	GDSC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1667
p.Q1744H	SIDM00868	Non-Cancerous	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.Q1744H	SIDM00868	Non-Cancerous	GDSC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1667
p.Q1744H	ACH-002287	Colon/Colorectal Cancer	CCLE	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0556
p.Q1744H	ACH-002287	Colon/Colorectal Cancer	CCLE	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1667
p.P2500Q	TCGA-E8-A2EA	THCA	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1111
p.P2500Q	DO38926	THCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1111
p.S4033I	TCGA-E9-A244	BRCA	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1111
p.S4033I	DO5263	BRCA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1111
p.G11629E	TCGA-EB-A24D	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1389
p.G11629E	DO37440	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1389
p.P4647S	TCGA-EB-A3XB	SKCM	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation altering degron motif	0.5641
p.P4647S	DO37856	SKCM	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation altering degron motif	0.5641
p.K1000N	TCGA-EB-A3XB	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation substituting flanking lysine	0.3333
p.K1000N	DO37856	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation substituting flanking lysine	0.3333
p.S2906F	TCGA-EB-A3XF	SKCM	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1667
p.S2906F	TCGA-EB-A3XF	SKCM	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.3056
p.S2906F	TCGA-GF-A6C9	SKCM	TCGA	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1667
p.S2906F	TCGA-GF-A6C9	SKCM	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.3056
p.S2906F	DO37437	SKCM	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1667
p.S2906F	DO37437	SKCM	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.3056
p.S2906F	DO51254	SKCM	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1667
p.S2906F	DO51254	SKCM	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.3056
p.R12367K	TCGA-EB-A3Y7	SKCM	TCGA	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367K	TCGA-EB-A3Y7	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.R12367K	DO37499	SKCM	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367K	DO37499	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.D4025V	TCGA-EB-A3Y7	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.7785
p.D4025V	DO37499	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.7785
p.S3466F	TCGA-EB-A3Y7	SKCM	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1667
p.S3466F	DO37499	SKCM	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1667
p.R13131W	TCGA-EB-A41A	SKCM	TCGA	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.0833
p.R13131W	DO37429	SKCM	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.0833
p.S9729F	TCGA-EB-A41B	SKCM	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1944
p.S9729F	DO37611	SKCM	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1944
p.G10932E	TCGA-EB-A42Z	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1944
p.G10932E	DO37414	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1944
p.S11083L	TCGA-EB-A430	SKCM	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6556
p.S11083L	DO37906	SKCM	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6556
p.G12525E	TCGA-EB-A431	SKCM	TCGA	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.0556
p.G12525E	TCGA-EB-A431	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2222
p.G12525E	DO37671	SKCM	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.0556
p.G12525E	DO37671	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2222
p.D9557N	TCGA-EB-A431	SKCM	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.D9557N	DO37671	SKCM	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.E6605K	TCGA-EB-A431	SKCM	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.2222
p.E6605K	DO37671	SKCM	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.2222
p.E919K	TCGA-EB-A4XL	SKCM	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.25
p.E919K	DO47401	SKCM	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.25
p.S9521F	TCGA-EB-A550	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2778
p.S9521F	DO229453	SKCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2778
p.S9521F	DO47265	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.2778
p.P12359S	TCGA-EB-A5UM	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6752
p.P12359S	TCGA-EE-A3JA	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6752
p.P12359S	DO47282	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6752
p.P12359S	DO47625	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6752
p.S6482L	TCGA-EB-A5UN	SKCM	TCGA	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1944
p.S6482L	DO47267	SKCM	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1944
p.P2416S	TCGA-EB-A6QY	SKCM	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation altering degron motif	0.5641
p.P2416S	DO48702	SKCM	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation altering degron motif	0.5641
p.P7473S	TCGA-EE-A17X	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.P7473S	TCGA-EE-A2MR	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.P7473S	TCGA-IR-A3LA	CESC	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.P7473S	DO44377	CESC	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.P7473S	DO37819	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.P7473S	DO37931	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.G10108E	TCGA-EE-A17Y	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	TCGA-EE-A3AA	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	DO222632	MELA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	DO37571	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	DO47459	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	SIDM00190	Melanoma	GDSC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.G10108E	CP66-MEL	skin	COSMIC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.6087
p.S3900F	TCGA-EE-A181	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation altering degron motif	0.9093
p.S3900F	DO37444	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation altering degron motif	0.9093
p.P7109S	TCGA-EE-A182	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.2778
p.P7109S	TCGA-EE-A182	SKCM	TCGA	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.3056
p.P7109S	DO37814	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.2778
p.P7109S	DO37814	SKCM	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.3056
p.A508T	TCGA-EE-A182	SKCM	TCGA	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.7139
p.A508T	DO37814	SKCM	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.7139
p.P3555H	TCGA-EE-A183	SKCM	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.0833
p.P3555H	DO37715	SKCM	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.0833
p.P11495S	TCGA-EE-A185	SKCM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495S	TCGA-IH-A3EA	SKCM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495S	DO220898	MELA	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495S	DO222658	MELA	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495S	DO37667	SKCM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495S	DO37599	SKCM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.G12836W	TCGA-EE-A20C	SKCM	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0833
p.G12836W	TCGA-EE-A20C	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2222
p.G12836W	DO47665	SKCM	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0833
p.G12836W	DO47665	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2222
p.P9751L	TCGA-EE-A20C	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.P9751L	DO222775	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.P9751L	DO47665	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.S2406F	TCGA-EE-A20C	SKCM	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.0833
p.S2406F	DO222775	MELA	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.0833
p.S2406F	DO47665	SKCM	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.0833
p.P896L	TCGA-EE-A20C	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.6471
p.P896L	DO222775	MELA	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.6471
p.P896L	DO47665	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.6471
p.D219N	TCGA-EE-A20C	SKCM	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.2222
p.D219N	DO222775	MELA	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.2222
p.D219N	DO47665	SKCM	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.2222
p.G10408R	TCGA-EE-A20H	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408R	TCGA-FW-A3R5	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408R	DO37406	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G10408R	DO37986	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.3056
p.G2314E	TCGA-EE-A29A	SKCM	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.0833
p.G2314E	DO37416	SKCM	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.0833
p.H10844Y	TCGA-EE-A29C	SKCM	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2222
p.H10844Y	DO222727	MELA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2222
p.H10844Y	DO38028	SKCM	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2222
p.G11876S	TCGA-EE-A29D	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.25
p.G11876S	TCGA-EE-A29D	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1111
p.G11876S	DO38123	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.25
p.G11876S	DO38123	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1111
p.S11534L	TCGA-EE-A29D	SKCM	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.8778
p.S11534L	DO229459	SKCA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.8778
p.S11534L	DO38123	SKCM	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.8778
p.S8282F	TCGA-EE-A29D	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	TCGA-FS-A1ZP	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	TCGA-GN-A266	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	TCGA-WE-A8ZN	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	DO220857	MELA	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	DO37703	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	DO37432	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	DO51285	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	DO38123	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	SIDM00860	Head and Neck Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	SIDM01154	T-Lymphoblastic Leukemia	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	ACH-000846	Head and Neck Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	ACH-000953	Leukemia	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8282F	FADU	upper aerodigestive tract	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8179F	TCGA-EE-A29D	SKCM	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation altering degron motif	0.7982
p.S8179F	DO220899	MELA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation altering degron motif	0.7982
p.S8179F	DO222527	MELA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation altering degron motif	0.7982
p.S8179F	DO38123	SKCM	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation altering degron motif	0.7982
p.P1490S	TCGA-EE-A29D	SKCM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.P1490S	DO222595	MELA	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.P1490S	DO38123	SKCM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.H10097Y	TCGA-EE-A29E	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.H10097Y	DO222644	MELA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.H10097Y	DO222753	MELA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.H10097Y	DO37831	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.P9754S	TCGA-EE-A29E	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.0833
p.P9754S	DO37831	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.0833
p.P9734L	TCGA-EE-A29E	SKCM	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7582
p.P9734L	DO37831	SKCM	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7582
p.S1733F	TCGA-EE-A29E	SKCM	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1733F	DO37831	SKCM	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1733F	SIDM00007	Other Solid Cancers	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1733F	ACH-001550	Skin Cancer	CCLE	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1733F	MCC13	skin	COSMIC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.E3103K	TCGA-EE-A29H	SKCM	TCGA	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.0556
p.E3103K	DO37535	SKCM	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.0556
p.G11096E	TCGA-EE-A29L	SKCM	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1111
p.G11096E	TCGA-EE-A29L	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1944
p.G11096E	TCGA-EE-A29L	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.G11096E	DO222599	MELA	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1111
p.G11096E	DO222599	MELA	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1944
p.G11096E	DO222599	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.G11096E	DO37835	SKCM	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1111
p.G11096E	DO37835	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.1944
p.G11096E	DO37835	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.E9428K	TCGA-EE-A29L	SKCM	TCGA	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	TCGA-ER-A1A1	SKCM	TCGA	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	DO220902	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	DO222599	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	DO37835	SKCM	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	DO37413	SKCM	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.E9428K	ACH-001523	Skin Cancer	CCLE	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.0833
p.P3237S	TCGA-EE-A29L	SKCM	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P3237S	TCGA-EE-A3AC	SKCM	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P3237S	DO220877	MELA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P3237S	DO222599	MELA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P3237S	DO37631	SKCM	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P3237S	DO37835	SKCM	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.P13291L	TCGA-EE-A29M	SKCM	TCGA	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation altering degron motif	0.6471
p.P13291L	DO37404	SKCM	ICGC	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation altering degron motif	0.6471
p.S11308L	TCGA-EE-A29M	SKCM	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.7667
p.S11308L	DO37404	SKCM	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.7667
p.G8781R	TCGA-EE-A29M	SKCM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781R	TCGA-EE-A29M	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.G8781R	DO37404	SKCM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781R	DO37404	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.G8781R	SIDM00755	Non-Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781R	SIDM00755	Non-Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.G8781R	ACH-000888	Lung Cancer	CCLE	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781R	ACH-000888	Lung Cancer	CCLE	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.G8781R	NCI-H1793	lung	COSMIC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781R	NCI-H1793	lung	COSMIC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.P894H	TCGA-EE-A29M	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.7694
p.P894H	DO37404	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.7694
p.R342K	TCGA-EE-A29N	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.R342K	DO38001	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.R342K	SIDM01175	Other Sarcomas	GDSC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.R342K	ACH-002309	Sarcoma	CCLE	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.R342K	SW684	soft tissue	COSMIC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.V10926L	TCGA-EE-A29P	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.5654
p.V10926L	DO37916	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.5654
p.S2094L	TCGA-EE-A29P	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1389
p.S2094L	TCGA-EE-A29P	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.3056
p.S2094L	DO37916	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.1389
p.S2094L	DO37916	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.3056
p.G11040E	TCGA-EE-A29T	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11040E	DO37742	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.G11093R	TCGA-EE-A29V	SKCM	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1944
p.G11093R	TCGA-EE-A29V	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.2778
p.G11093R	TCGA-EE-A29V	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2222
p.G11093R	DO38006	SKCM	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1944
p.G11093R	DO38006	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.2778
p.G11093R	DO38006	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2222
p.D5757N	TCGA-EE-A29V	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.D5757N	TCGA-EO-A22U	UCEC	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.D5757N	DO38006	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.D5757N	DO43755	UCEC	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.E546K	TCGA-EE-A29V	SKCM	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.E546K	TCGA-GN-A267	SKCM	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.E546K	DO218874	SKCA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.E546K	DO38006	SKCM	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.E546K	DO38147	SKCM	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.25
p.G11051V	TCGA-EE-A29X	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.3056
p.G11051V	DO37595	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.3056
p.L7999F	TCGA-EE-A2A1	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.0556
p.L7999F	DO48387	BLCA	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.0556
p.L7999F	DO38045	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.0556
p.V13145L	TCGA-EE-A2GB	SKCM	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.V13145L	TCGA-EE-A2GB	SKCM	TCGA	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.3056
p.V13145L	DO222683	MELA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.V13145L	DO222683	MELA	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.3056
p.V13145L	DO37417	SKCM	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2222
p.V13145L	DO37417	SKCM	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.3056
p.S2084G	TCGA-EE-A2GB	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation altering degron motif	0.5882
p.S2084G	DO222683	MELA	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation altering degron motif	0.5882
p.S2084G	DO37417	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation altering degron motif	0.5882
p.G12360E	TCGA-EE-A2GC	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6087
p.G12360E	DO37839	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation altering degron motif	0.6087
p.P11593L	TCGA-EE-A2GC	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.P11593L	DO37839	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.M11191I	TCGA-EE-A2GC	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.0556
p.M11191I	DO37839	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.0556
p.S7971F	TCGA-EE-A2GD	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1389
p.S7971F	DO218847	SKCA	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1389
p.S7971F	DO37603	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1389
p.P9334Q	TCGA-EE-A2GH	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1944
p.P9334Q	DO37643	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1944
p.E1667K	TCGA-EE-A2GH	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.E1667K	DO37643	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1944
p.S11702F	TCGA-EE-A2GI	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.25
p.S11702F	TCGA-EE-A2GJ	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.25
p.S11702F	DO37746	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.25
p.S11702F	DO37410	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.25
p.D3431N	TCGA-EE-A2GN	SKCM	TCGA	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.D3431N	DO37896	SKCM	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.P12997L	TCGA-EE-A2GO	SKCM	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.0556
p.P12997L	TCGA-EE-A2GO	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.P12997L	DO37823	SKCM	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.0556
p.P12997L	DO37823	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.0833
p.V11250A	TCGA-EE-A2GO	SKCM	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6936
p.V11250A	DO37823	SKCM	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6936
p.S3008F	TCGA-EE-A2GO	SKCM	TCGA	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.3056
p.S3008F	DO37823	SKCM	ICGC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.3056
p.A935V	TCGA-EE-A2GP	SKCM	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0833
p.A935V	DO37422	SKCM	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0833
p.S8101L	TCGA-EE-A2GS	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.7667
p.S8101L	DO37465	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.7667
p.G12992V	TCGA-EE-A2GT	SKCM	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.G12992V	TCGA-EE-A2GT	SKCM	TCGA	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0833
p.G12992V	TCGA-EE-A2GT	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.2222
p.G12992V	DO37946	SKCM	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1944
p.G12992V	DO37946	SKCM	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0833
p.G12992V	DO37946	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.2222
p.G11093V	TCGA-EE-A2GT	SKCM	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1944
p.G11093V	TCGA-EE-A2GT	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.2778
p.G11093V	TCGA-EE-A2GT	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2222
p.G11093V	DO37946	SKCM	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1944
p.G11093V	DO37946	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation rewiring degron network	0.2778
p.G11093V	DO37946	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2222
p.S10333F	TCGA-EE-A2M5	SKCM	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10333F	DO222423	MELA	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10333F	DO222868	MELA	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.S10333F	DO37425	SKCM	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.7982
p.P1084L	TCGA-EE-A2M5	SKCM	TCGA	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1389
p.P1084L	DO222423	MELA	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1389
p.P1084L	DO37425	SKCM	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1389
p.S4011F	TCGA-EE-A2M6	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	TCGA-EE-A3AG	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	TCGA-FS-A1ZT	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	TCGA-GN-A266	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO220911	MELA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO222514	MELA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO37471	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO37468	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO37432	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.S4011F	DO37976	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.G12995E	TCGA-EE-A2MC	SKCM	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	TCGA-EE-A2MC	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	DO228825	LICA	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	DO228825	LICA	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	DO222426	MELA	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	DO222426	MELA	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	DO37559	SKCM	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	DO37559	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	SIDM00140	Melanoma	GDSC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	SIDM00140	Melanoma	GDSC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	ACH-000968	Skin Cancer	CCLE	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	ACH-000968	Skin Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995E	COLO-792	skin	COSMIC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995E	COLO-792	skin	COSMIC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.M4024I	TCGA-EE-A2MF	SKCM	TCGA	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6507
p.M4024I	DO222491	MELA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6507
p.M4024I	DO51249	SKCM	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6507
p.E5088K	TCGA-EE-A2MI	SKCM	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.3056
p.E5088K	DO37531	SKCM	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.3056
p.T1012A	TCGA-EE-A2MI	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.2222
p.T1012A	DO37531	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.2222
p.G11807D	TCGA-EE-A2MK	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.3056
p.G11807D	DO222615	MELA	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.3056
p.G11807D	DO38177	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.3056
p.S10863L	TCGA-EE-A2ML	SKCM	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7667
p.S10863L	TCGA-EE-A2ML	SKCM	TCGA	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.8778
p.S10863L	DO222429	MELA	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7667
p.S10863L	DO222429	MELA	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.8778
p.S10863L	DO37408	SKCM	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7667
p.S10863L	DO37408	SKCM	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.8778
p.T10812K	TCGA-EE-A2ML	SKCM	TCGA	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1667
p.T10812K	DO222429	MELA	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1667
p.T10812K	DO37408	SKCM	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1667
p.E10406K	TCGA-EE-A2MR	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.E10406K	DO37819	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.25
p.M8912I	TCGA-EE-A2MR	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.2222
p.M8912I	DO37819	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.2222
p.T6600I	TCGA-EE-A2MR	SKCM	TCGA	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation altering degron motif	0.7078
p.T6600I	DO37819	SKCM	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation altering degron motif	0.7078
p.S5822F	TCGA-EE-A2MR	SKCM	TCGA	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation altering degron motif	0.7982
p.S5822F	DO37819	SKCM	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation altering degron motif	0.7982
p.E692K	TCGA-EE-A2MR	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.2222
p.E692K	DO37819	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.2222
p.M193I	TCGA-EE-A2MR	SKCM	TCGA	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0833
p.M193I	DO222868	MELA	ICGC	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0833
p.M193I	DO37819	SKCM	ICGC	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0833
p.S5649L	TCGA-EE-A2MS	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.3056
p.S5649L	DO37567	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.3056
p.G3546E	TCGA-EE-A2MS	SKCM	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1389
p.G3546E	DO37567	SKCM	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1389
p.P3536S	TCGA-EE-A2MS	SKCM	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.6752
p.P3536S	DO37567	SKCM	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.6752
p.T11117N	TCGA-EE-A3AA	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.1667
p.T11117N	DO222632	MELA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.1667
p.T11117N	DO37571	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.1667
p.G7334V	TCGA-EE-A3AA	SKCM	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6421
p.G7334V	DO37571	SKCM	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6421
p.A994V	TCGA-EE-A3AA	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0556
p.A994V	TCGA-RP-A694	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0556
p.A994V	DO222632	MELA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0556
p.A994V	DO37571	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0556
p.A994V	DO51269	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0556
p.R11615T	TCGA-EE-A3AB	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.25
p.R11615T	DO222670	MELA	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.25
p.R11615T	DO38057	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.25
p.P11010S	TCGA-EE-A3AC	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.0833
p.P11010S	DO37631	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.0833
p.P7714L	TCGA-EE-A3AC	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P7714L	TCGA-FW-A3R5	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P7714L	DO229462	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P7714L	DO37631	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P7714L	DO37406	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.L2520F	TCGA-EE-A3AC	SKCM	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1111
p.L2520F	DO37631	SKCM	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1111
p.L365F	TCGA-EE-A3AC	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.L365F	DO37631	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.G10929W	TCGA-EE-A3AD	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.G10929W	DO37707	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.P5327S	TCGA-EE-A3AE	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6752
p.P5327S	TCGA-FI-A2D5	UCEC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6752
p.P5327S	DO37802	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6752
p.P5327S	DO41331	UCEC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6752
p.E5627K	TCGA-EE-A3AG	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.3056
p.E5627K	DO37471	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.3056
p.L440F	TCGA-EE-A3AG	SKCM	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1389
p.L440F	DO37471	SKCM	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1389
p.P10866L	TCGA-EE-A3J5	SKCM	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7582
p.P10866L	TCGA-EE-A3J5	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation altering degron motif	0.6471
p.P10866L	DO47331	SKCM	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7582
p.P10866L	DO47331	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation altering degron motif	0.6471
p.T9318I	TCGA-EE-A3J7	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1389
p.T9318I	DO48770	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1389
p.S8064F	TCGA-EE-A3J7	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation altering degron motif	0.7982
p.S8064F	DO48770	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation altering degron motif	0.7982
p.S561F	TCGA-EE-A3J7	SKCM	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.S561F	DO220886	MELA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.S561F	DO48770	SKCM	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.R2104K	TCGA-EE-A3J8	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.R2104K	TCGA-FR-A726	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.R2104K	TCGA-FW-A3R5	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.R2104K	DO47276	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.R2104K	DO37406	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.R2104K	DO48665	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.E3571K	TCGA-EE-A3JA	SKCM	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.7022
p.E3571K	DO47625	SKCM	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.7022
p.G11961R	TCGA-EE-A3JD	SKCM	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1944
p.G11961R	DO50299	SKCM	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1944
p.G10876R	TCGA-EE-A3JD	SKCM	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1111
p.G10876R	TCGA-EE-A3JD	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.1944
p.G10876R	TCGA-EE-A3JD	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.3056
p.G10876R	DO50299	SKCM	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1111
p.G10876R	DO50299	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.1944
p.G10876R	DO50299	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.3056
p.H7472Y	TCGA-EE-A3JD	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0556
p.H7472Y	DO50299	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0556
p.T4463I	TCGA-EE-A3JD	SKCM	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.25
p.T4463I	DO50299	SKCM	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.25
p.P2091S	TCGA-EE-A3JD	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	TCGA-EE-A3JD	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.P2091S	TCGA-FR-A8YC	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	TCGA-FR-A8YC	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.P2091S	DO229459	SKCA	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	DO229459	SKCA	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.P2091S	DO50301	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	DO50301	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.P2091S	DO50299	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	DO50299	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.P2091S	ACH-002005	Skin Cancer	CCLE	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.P2091S	ACH-002005	Skin Cancer	CCLE	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.2222
p.D6873N	TCGA-EF-5830	READ	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0833
p.D6873N	DO36551	READ	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0833
p.T11393I	TCGA-EI-6507	READ	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.2778
p.T11393I	DO36675	READ	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.2778
p.G12995W	TCGA-EI-6917	READ	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995W	TCGA-EI-6917	READ	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.G12995W	DO36881	READ	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1111
p.G12995W	DO36881	READ	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1389
p.A340V	TCGA-EI-6917	READ	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0556
p.A340V	DO36881	READ	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0556
p.H11511Y	TCGA-EJ-5496	PRAD	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.H11511Y	DO36266	PRAD	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.T9563R	TCGA-EJ-7782	PRAD	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation blocking phosphorylation signal	0.5
p.T9563R	DO36256	PRAD	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation blocking phosphorylation signal	0.5
p.T2461K	TCGA-EM-A2CR	THCA	TCGA	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8417
p.T2461K	DO40729	THCA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8417
p.L9735I	TCGA-EO-A22R	UCEC	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.6063
p.L9735I	DO42713	UCEC	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.6063
p.P9734H	TCGA-EO-A22R	UCEC	TCGA	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7694
p.P9734H	DO42713	UCEC	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7694
p.T8216A	TCGA-EO-A22R	UCEC	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.T8216A	DO230940	LUSC	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.T8216A	DO224584	LUSC	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.T8216A	DO42713	UCEC	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.S7807R	TCGA-EO-A22R	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.S7807R	DO42713	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.E3219D	TCGA-EO-A22R	UCEC	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.0833
p.E3219D	DO42713	UCEC	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.0833
p.V9545A	TCGA-EO-A22T	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.V9545A	DO42320	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.R9330I	TCGA-EO-A22X	UCEC	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.R9330I	DO43907	UCEC	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.S11889I	TCGA-EO-A3AY	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation blocking phosphorylation signal	0.6111
p.S11889I	TCGA-EO-A3AY	UCEC	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.75
p.S11889I	DO43202	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation blocking phosphorylation signal	0.6111
p.S11889I	DO43202	UCEC	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation blocking phosphorylation signal	0.75
p.P12004H	TCGA-EO-A3B0	UCEC	TCGA	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation altering degron motif	0.7694
p.P12004H	DO229029	LICA	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation altering degron motif	0.7694
p.P12004H	DO219773	UCEC	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation altering degron motif	0.7694
p.S8774Y	TCGA-EO-A3B0	UCEC	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.6009
p.S8774Y	DO219773	UCEC	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.6009
p.R8185K	TCGA-EO-A3B0	UCEC	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1944
p.R8185K	DO219773	UCEC	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1944
p.S913P	TCGA-EO-A3KX	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0833
p.S913P	DO219774	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0833
p.P548T	TCGA-EQ-A4SO	STAD	TCGA	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.3056
p.P548T	DO47893	STAD	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.3056
p.G10428D	TCGA-ER-A193	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.0833
p.G10428D	DO47368	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.0833
p.H9513P	TCGA-ER-A193	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513P	DO47368	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.G3435E	TCGA-ER-A194	SKCM	TCGA	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.0833
p.G3435E	DO47646	SKCM	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.0833
p.S7987F	TCGA-ER-A19E	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	DO220862	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	DO220889	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	DO47542	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	SIDM01159	Other Sarcomas	GDSC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	ACH-002310	Liposarcoma	CCLE	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.S7987F	SW872	soft tissue	COSMIC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7982
p.N952S	TCGA-ER-A19F	SKCM	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0556
p.N952S	DO37679	SKCM	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.0556
p.P11058L	TCGA-ER-A19G	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1111
p.P11058L	DO47284	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1111
p.E6892K	TCGA-ER-A19G	SKCM	TCGA	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.E6892K	DO47284	SKCM	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.E6892K	SIDM01251	T-Cell Non-Hodgkin's Lymphoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.E6892K	ACH-000509	Lymphoma	CCLE	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.E6892K	ACH-002240	Lymphoma	CCLE	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.E6892K	H9	haematopoietic and lymphoid tissue	COSMIC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.1667
p.P8086S	TCGA-ER-A19M	SKCM	TCGA	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.2778
p.P8086S	DO37798	SKCM	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.2778
p.E2089K	TCGA-ER-A19O	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089K	TCGA-ER-A19O	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.E2089K	TCGA-Z2-A8RT	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089K	TCGA-Z2-A8RT	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.E2089K	DO38063	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089K	DO38063	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.E2089K	DO51301	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089K	DO51301	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.S9752F	TCGA-ER-A3PL	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1389
p.S9752F	TCGA-QH-A6CX	LGG	TCGA	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1389
p.S9752F	DO50171	LGG	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1389
p.S9752F	DO37495	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1389
p.T7347I	TCGA-ER-A3PL	SKCM	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.0556
p.T7347I	DO37495	SKCM	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.0556
p.T5810N	TCGA-ER-A42L	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation altering degron motif	0.8166
p.T5810N	DO223910	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation altering degron motif	0.8166
p.A7295S	TCGA-EW-A1J6	BRCA	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1111
p.A7295S	DO4227	BRCA	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1111
p.M1825L	TCGA-EY-A1G8	UCEC	TCGA	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.5999
p.M1825L	TCGA-EY-A1G8	UCEC	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.5999
p.M1825L	DO43578	UCEC	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.5999
p.M1825L	DO43578	UCEC	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.5999
p.L12366I	TCGA-EY-A1GI	UCEC	TCGA	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.L12366I	TCGA-EY-A1GI	UCEC	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.25
p.L12366I	DO41211	UCEC	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.L12366I	DO41211	UCEC	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.25
p.S9459F	TCGA-EY-A1GI	UCEC	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.2222
p.S9459F	DO41211	UCEC	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.2222
p.P3568L	TCGA-EY-A215	UCEC	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.7582
p.P3568L	DO42665	UCEC	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.7582
p.H10097R	TCGA-F1-6177	STAD	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.H10097R	DO38727	STAD	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0556
p.L12835R	TCGA-F5-6814	READ	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1111
p.L12835R	TCGA-F5-6814	READ	TCGA	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.25
p.L12835R	DO36556	READ	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1111
p.L12835R	DO36556	READ	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.25
p.S12352F	TCGA-F5-6814	READ	TCGA	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.3056
p.S12352F	TCGA-F5-6814	READ	TCGA	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1389
p.S12352F	DO36556	READ	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.3056
p.S12352F	DO36556	READ	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.1389
p.D12209N	TCGA-F5-6814	READ	TCGA	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1389
p.D12209N	TCGA-F5-6814	READ	TCGA	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2778
p.D12209N	DO36556	READ	ICGC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1389
p.D12209N	DO36556	READ	ICGC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2778
p.D12209N	SIDM00282	Colorectal Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1389
p.D12209N	SIDM00282	Colorectal Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2778
p.D12209N	ACH-000998	Colon/Colorectal Cancer	CCLE	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1389
p.D12209N	ACH-000998	Colon/Colorectal Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2778
p.D12209N	CW-2	large intestine	COSMIC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1389
p.D12209N	CW-2	large intestine	COSMIC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.2778
p.R8772I	TCGA-F5-6814	READ	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.3056
p.R8772I	TCGA-F5-6814	READ	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.2222
p.R8772I	DO36556	READ	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.3056
p.R8772I	DO36556	READ	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.2222
p.E8181K	TCGA-F5-6814	READ	TCGA	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.E8181K	DO36556	READ	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.3056
p.L7732V	TCGA-F5-6814	READ	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.L7732V	TCGA-F5-6814	READ	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1667
p.L7732V	DO36556	READ	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.L7732V	DO36556	READ	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1667
p.T3235I	TCGA-F5-6814	READ	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.7078
p.T3235I	DO36556	READ	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.7078
p.E1761K	TCGA-F5-6814	READ	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7022
p.E1761K	DO36556	READ	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7022
p.G3467A	TCGA-FD-A3NA	BLCA	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.G3467A	DO602	BLCA	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1389
p.L11045V	TCGA-FD-A6TB	BLCA	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.3056
p.L11045V	DO51879	BLCA	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.3056
p.P1491S	TCGA-FD-A6TB	BLCA	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6752
p.P1491S	TCGA-FW-A3R5	SKCM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6752
p.P1491S	DO51879	BLCA	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6752
p.P1491S	DO37406	SKCM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6752
p.S3711C	TCGA-FD-A6TC	BLCA	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.S3711C	DO49755	BLCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.T1822S	TCGA-FG-6690	LGG	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.7116
p.T1822S	DO22141	LGG	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.7116
p.E11769K	TCGA-FI-A2D0	UCEC	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1111
p.E11769K	DO43891	UCEC	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1111
p.T9563I	TCGA-FI-A2D5	UCEC	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation blocking phosphorylation signal	0.5
p.T9563I	DO41331	UCEC	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation blocking phosphorylation signal	0.5
p.V9265A	TCGA-FI-A2D5	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.5825
p.V9265A	DO41331	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.5825
p.T7749A	TCGA-FI-A2D5	UCEC	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1389
p.T7749A	DO41331	UCEC	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1389
p.I6334T	TCGA-FI-A2D5	UCEC	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.5966
p.I6334T	DO41331	UCEC	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.5966
p.S4875L	TCGA-FI-A2D5	UCEC	TCGA	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation blocking phosphorylation signal	0.5278
p.S4875L	DO41331	UCEC	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation blocking phosphorylation signal	0.5278
p.T3532A	TCGA-FI-A2D5	UCEC	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2778
p.T3532A	DO41331	UCEC	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2778
p.T14A	TCGA-FI-A2D5	UCEC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.2778
p.T14A	DO41331	UCEC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.2778
p.P12666S	TCGA-FJ-A3ZE	BLCA	TCGA	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.3056
p.P12666S	DO484	BLCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.3056
p.T10109N	TCGA-FJ-A3ZE	BLCA	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.7055
p.T10109N	DO484	BLCA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation altering degron motif	0.7055
p.A9815D	TCGA-FJ-A3ZE	BLCA	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.2778
p.A9815D	DO484	BLCA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.2778
p.A7726V	TCGA-FP-A4BE	STAD	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.5825
p.A7726V	DO223034	ESCA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.5825
p.A7726V	DO48016	STAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.5825
p.P1193L	TCGA-FR-A3YO	SKCM	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.25
p.P1193L	DO37419	SKCM	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.25
p.P12517S	TCGA-FR-A726	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation altering degron motif	0.6752
p.P12517S	TCGA-GN-A266	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation altering degron motif	0.6752
p.P12517S	DO37432	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation altering degron motif	0.6752
p.P12517S	DO48665	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation altering degron motif	0.6752
p.V11502I	TCGA-FR-A726	SKCM	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.V11502I	DO48665	SKCM	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.P9460S	TCGA-FR-A726	SKCM	TCGA	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.1944
p.P9460S	DO48665	SKCM	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.1944
p.L7F	TCGA-FR-A726	SKCM	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.3056
p.L7F	DO48665	SKCM	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.3056
p.G8104S	TCGA-FR-A728	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.G8104S	DO48550	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.P8789S	TCGA-FR-A7U9	SKCM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789S	TCGA-FR-A7U9	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789S	DO48546	SKCM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789S	DO48546	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.S5351F	TCGA-FR-A7U9	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7982
p.S5351F	DO220890	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7982
p.S5351F	DO229462	SKCA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7982
p.S5351F	DO48546	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7982
p.E1809K	TCGA-FR-A7U9	SKCM	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0556
p.E1809K	TCGA-WE-A8K4	SKCM	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0556
p.E1809K	DO48546	SKCM	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0556
p.E1809K	DO51281	SKCM	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.0556
p.P13608S	TCGA-FR-A8YC	SKCM	TCGA	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	DO220851	MELA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	DO222731	MELA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	DO50301	SKCM	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	SIDM01059	Melanoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	ACH-000915	Skin Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.P13608S	IPC-298	skin	COSMIC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.T10782S	TCGA-FR-A8YC	SKCM	TCGA	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.2222
p.T10782S	DO50301	SKCM	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.2222
p.S7485F	TCGA-FR-A8YC	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.7982
p.S7485F	DO50301	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.7982
p.G7293S	TCGA-FR-A8YC	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1667
p.G7293S	DO50301	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1667
p.S5337F	TCGA-FR-A8YC	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1389
p.S5337F	DO50301	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1389
p.P706L	TCGA-FR-A8YC	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.P706L	DO50301	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.M11151I	TCGA-FS-A1Z0	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.M11151I	DO37431	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.M11151I	SIDM00336	Melanoma	GDSC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.M11151I	ACH-000881	Skin Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.M11151I	MEL-JUSO	skin	COSMIC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.W11238C	TCGA-FS-A1ZB	SKCM	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238C	DO230343	COCA	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238C	DO37886	SKCM	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238C	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238C	ACH-000694	Esophageal Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238C	TE-9	oesophagus	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.E3988K	TCGA-FS-A1ZC	SKCM	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.25
p.E3988K	TCGA-FW-A3R5	SKCM	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.25
p.E3988K	DO37406	SKCM	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.25
p.E3988K	DO37487	SKCM	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.25
p.S959F	TCGA-FS-A1ZC	SKCM	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation blocking phosphorylation signal	0.6944
p.S959F	DO37487	SKCM	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation blocking phosphorylation signal	0.6944
p.W11690C	TCGA-FS-A1ZG	SKCM	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1944
p.W11690C	DO37523	SKCM	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1944
p.D8205N	TCGA-FS-A1ZK	SKCM	TCGA	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.D8205N	DO37474	SKCM	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.2778
p.G7515V	TCGA-FS-A1ZP	SKCM	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1389
p.G7515V	DO37703	SKCM	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1389
p.P5623L	TCGA-FS-A1ZP	SKCM	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7582
p.P5623L	DO37703	SKCM	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7582
p.S11187F	TCGA-FS-A1ZW	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1667
p.S11187F	DO37519	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1667
p.P10554S	TCGA-FS-A1ZW	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.25
p.P10554S	TCGA-GF-A6C9	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.25
p.P10554S	DO37519	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.25
p.P10554S	DO51254	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.25
p.S1481L	TCGA-FS-A4FC	SKCM	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.S1481L	DO37762	SKCM	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.E7737D	TCGA-FU-A3HZ	CESC	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1111
p.E7737D	TCGA-FU-A3HZ	CESC	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.3056
p.E7737D	DO6308	CESC	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1111
p.E7737D	DO6308	CESC	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.3056
p.A12014V	TCGA-FW-A3R5	SKCM	TCGA	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.1389
p.A12014V	DO37406	SKCM	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.1389
p.A11575V	TCGA-FW-A3R5	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.A11575V	DO37406	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.S11294F	TCGA-FW-A3R5	SKCM	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1389
p.S11294F	DO37406	SKCM	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1389
p.S10861F	TCGA-FW-A3R5	SKCM	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6871
p.S10861F	TCGA-FW-A3R5	SKCM	TCGA	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7982
p.S10861F	DO222875	MELA	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6871
p.S10861F	DO222875	MELA	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7982
p.S10861F	DO37406	SKCM	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6871
p.S10861F	DO37406	SKCM	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7982
p.E8316K	TCGA-FW-A3R5	SKCM	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.3056
p.E8316K	DO37406	SKCM	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.3056
p.S7719L	TCGA-FW-A3R5	SKCM	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1667
p.S7719L	DO37406	SKCM	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1667
p.S5638F	TCGA-FW-A3R5	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.S5638F	DO37406	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.P5165S	TCGA-FW-A3R5	SKCM	TCGA	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation altering degron motif	0.5641
p.P5165S	DO37406	SKCM	ICGC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation altering degron motif	0.5641
p.S4597F	TCGA-FW-A3R5	SKCM	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.S4597F	TCGA-LP-A4AV	CESC	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.S4597F	DO44275	CESC	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.S4597F	DO37406	SKCM	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.P3228S	TCGA-FW-A3R5	SKCM	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.6752
p.P3228S	DO37406	SKCM	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.6752
p.E3104K	TCGA-FW-A3R5	SKCM	TCGA	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.0833
p.E3104K	DO37406	SKCM	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.0833
p.P2735L	TCGA-FW-A3R5	SKCM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2735L	TCGA-W3-A825	SKCM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2735L	DO37406	SKCM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2735L	DO51272	SKCM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2724L	TCGA-FW-A3R5	SKCM	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7582
p.P2724L	TCGA-NC-A5HM	LUSC	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7582
p.P2724L	DO219195	LUSC	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7582
p.P2724L	DO37406	SKCM	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7582
p.G2518S	TCGA-FW-A3R5	SKCM	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1667
p.G2518S	DO37406	SKCM	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1667
p.P2106L	TCGA-FW-A3R5	SKCM	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.P2106L	DO37406	SKCM	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.G2079R	TCGA-FW-A3R5	SKCM	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.G2079R	DO37406	SKCM	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2222
p.E143K	TCGA-FW-A3R5	SKCM	TCGA	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1111
p.E143K	DO37406	SKCM	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1111
p.V11041L	TCGA-FX-A2QS	SARC	TCGA	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.V11041L	DO220116	SARC	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.S7527Y	TCGA-G2-A2ES	BLCA	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.8231
p.S7527Y	DO785	BLCA	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.8231
p.S1983F	TCGA-G2-A3IB	BLCA	TCGA	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.1667
p.S1983F	DO512	BLCA	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.1667
p.S2463W	TCGA-G2-A3IE	BLCA	TCGA	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7874
p.S2463W	DO767	BLCA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7874
p.S7743Y	TCGA-G2-AA3D	BLCA	TCGA	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.3056
p.S7743Y	DO51884	BLCA	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.3056
p.S7789Y	TCGA-G4-6298	COAD	TCGA	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.1111
p.S7789Y	DO7834	COAD	ICGC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.1111
p.L1443M	TCGA-G4-6309	COAD	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.2778
p.L1443M	DO7810	COAD	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.2778
p.E5176D	TCGA-G4-6625	COAD	TCGA	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1111
p.E5176D	DO9266	COAD	ICGC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1111
p.T8685R	TCGA-G9-6496	PRAD	TCGA	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.2222
p.T8685R	TCGA-G9-6496	PRAD	TCGA	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.2778
p.T8685R	DO36344	PRAD	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.2222
p.T8685R	DO36344	PRAD	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.2778
p.T11586R	TCGA-GC-A4ZW	BLCA	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7876
p.T11586R	DO219024	BLCA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7876
p.S2725C	TCGA-GD-A2C5	BLCA	TCGA	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.643
p.S2725C	DO496	BLCA	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.643
p.P712L	TCGA-GF-A6C8	SKCM	TCGA	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.0833
p.P712L	DO48765	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.0833
p.T12817I	TCGA-GF-A6C9	SKCM	TCGA	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1667
p.T12817I	DO51254	SKCM	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1667
p.S11173F	TCGA-GF-A6C9	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1111
p.S11173F	TCGA-GF-A6C9	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2222
p.S11173F	DO51254	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1111
p.S11173F	DO51254	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2222
p.S3726F	TCGA-GF-A6C9	SKCM	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	DO51254	SKCM	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	SIDM01106	Melanoma	GDSC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	SIDM01768	Melanoma	GDSC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	ACH-000822	Skin Cancer	CCLE	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	ACH-000899	Skin Cancer	CCLE	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S3726F	SK-MEL-24	skin	COSMIC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.6871
p.S927L	TCGA-GF-A6C9	SKCM	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation blocking phosphorylation signal	0.75
p.S927L	DO51254	SKCM	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation blocking phosphorylation signal	0.75
p.E52K	TCGA-GF-A6C9	SKCM	TCGA	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1389
p.E52K	DO51254	SKCM	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1389
p.P223A	TCGA-GM-A3NW	BRCA	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.1111
p.P223A	DO3001	BRCA	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.1111
p.G13616E	TCGA-GN-A262	SKCM	TCGA	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0556
p.G13616E	DO222837	MELA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0556
p.G13616E	DO37515	SKCM	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0556
p.P9334T	TCGA-GN-A262	SKCM	TCGA	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1944
p.P9334T	DO37515	SKCM	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1944
p.S10118F	TCGA-GN-A266	SKCM	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1389
p.S10118F	DO37432	SKCM	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1389
p.S7982L	TCGA-GN-A266	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation altering degron motif	0.7667
p.S7982L	DO37432	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation altering degron motif	0.7667
p.P5359S	TCGA-GN-A266	SKCM	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.P5359S	DO37432	SKCM	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.S4640Y	TCGA-GN-A266	SKCM	TCGA	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.1667
p.S4640Y	DO37432	SKCM	ICGC	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.1667
p.S3227F	TCGA-GN-A266	SKCM	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.S3227F	DO37432	SKCM	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.3056
p.M2517I	TCGA-GN-A266	SKCM	TCGA	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1944
p.M2517I	DO222749	MELA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1944
p.M2517I	DO37432	SKCM	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.1944
p.S971G	TCGA-GN-A268	SKCM	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1944
p.S971G	DO37477	SKCM	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1944
p.T8997A	TCGA-GN-A269	SKCM	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.25
p.T8997A	DO37483	SKCM	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.25
p.P4941S	TCGA-GN-A26C	SKCM	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.P4941S	DO37782	SKCM	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.P10875Q	TCGA-GN-A26D	SKCM	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1389
p.P10875Q	TCGA-GN-A26D	SKCM	TCGA	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.2222
p.P10875Q	TCGA-GN-A26D	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.P10875Q	DO37480	SKCM	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1389
p.P10875Q	DO37480	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.2222
p.P10875Q	DO37480	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.P11392S	TCGA-GN-A4U4	SKCM	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.25
p.P11392S	DO51256	SKCM	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.25
p.T7523A	TCGA-GN-A4U5	SKCM	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.825
p.T7523A	DO51257	SKCM	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.825
p.G1727R	TCGA-GN-A4U5	SKCM	TCGA	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727R	DO51257	SKCM	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.S10919F	TCGA-GN-A4U8	SKCM	TCGA	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S10919F	DO47320	SKCM	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S10919F	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S10919F	ACH-000353	Esophageal Cancer	CCLE	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S10919F	TE-15	oesophagus	COSMIC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.2778
p.S6344F	TCGA-GN-A8LK	SKCM	TCGA	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.1389
p.S6344F	DO51259	SKCM	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.1389
p.G2314R	TCGA-GN-A8LK	SKCM	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.0833
p.G2314R	DO229502	SKCA	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.0833
p.G2314R	DO51259	SKCM	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.0833
p.T3712A	TCGA-GV-A3QH	BLCA	TCGA	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0833
p.T3712A	DO464	BLCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0833
p.I9555V	TCGA-GV-A3QI	BLCA	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2778
p.I9555V	DO470	BLCA	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2778
p.S5465Y	TCGA-GV-A6ZA	BLCA	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation altering degron motif	0.712
p.S5465Y	DO49776	BLCA	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation altering degron motif	0.712
p.F461Y	TCGA-HC-7744	PRAD	TCGA	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.F461Y	DO36283	PRAD	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2778
p.S6046P	TCGA-HC-A6HY	PRAD	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1389
p.S6046P	DO49826	PRAD	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1389
p.T7989I	TCGA-HT-7860	LGG	TCGA	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7078
p.T7989I	DO22614	LGG	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.7078
p.I1980S	TCGA-HU-A4GH	STAD	TCGA	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.I1980S	DO47743	STAD	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.P11525H	TCGA-HU-A4GU	STAD	TCGA	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1389
p.P11525H	DO47849	STAD	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1389
p.Q10415H	TCGA-HU-A4H3	STAD	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.647
p.Q10415H	DO47903	STAD	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.647
p.T11770A	TCGA-IB-7651	PAAD	TCGA	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.T11770A	DO46657	PAAD	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.F11509C	TCGA-IB-7651	PAAD	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.5996
p.F11509C	DO46657	PAAD	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.5996
p.L11118I	TCGA-IB-7651	PAAD	TCGA	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.1389
p.L11118I	DO46657	PAAD	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.1389
p.I8773V	TCGA-IB-7651	PAAD	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.5965
p.I8773V	DO46657	PAAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.5965
p.R8310M	TCGA-IB-7651	PAAD	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.R8310M	DO46657	PAAD	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.F2090C	TCGA-IB-7651	PAAD	TCGA	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.25
p.F2090C	TCGA-IB-7651	PAAD	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.F2090C	DO46657	PAAD	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.25
p.F2090C	DO46657	PAAD	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.M10102I	TCGA-IB-A5SP	PAAD	TCGA	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1944
p.M10102I	DO46635	PAAD	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1944
p.I2917M	TCGA-IC-A6RE	ESCA	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.2222
p.A2322V	TCGA-IG-A50L	ESCA	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.3056
p.G11427S	TCGA-IH-A3EA	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation rewiring degron network	0.2778
p.G11427S	DO37667	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation rewiring degron network	0.2778
p.P10028S	TCGA-IH-A3EA	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation altering degron motif	0.6752
p.P10028S	DO37667	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation altering degron motif	0.6752
p.P7711L	TCGA-IH-A3EA	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.P7711L	DO229054	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.P7711L	DO37667	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.P7711S	TCGA-IH-A3EA	SKCM	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.P7711S	DO229453	SKCA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.P7711S	DO37667	SKCM	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1667
p.S356F	TCGA-IH-A3EA	SKCM	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.7982
p.S356F	DO37667	SKCM	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.7982
p.S11707R	TCGA-IN-A6RN	STAD	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1111
p.S11707R	DO51739	STAD	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1111
p.S5336F	TCGA-IR-A3LA	CESC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1667
p.S5336F	DO44377	CESC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1667
p.L3285V	TCGA-IR-A3LA	CESC	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.0556
p.L3285V	DO44377	CESC	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.0556
p.S8161C	TCGA-J1-A4AH	LUSC	TCGA	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7541
p.S8161C	DO45479	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.7541
p.Q5473E	TCGA-JW-A5VJ	CESC	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.Q5473E	DO49974	CESC	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1944
p.S2099Y	TCGA-JY-A6FG	ESCA	TCGA	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation altering degron motif	0.712
p.S1832C	TCGA-K4-A54R	BLCA	TCGA	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.7541
p.S1832C	DO48611	BLCA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.7541
p.S9828F	TCGA-KK-A6E7	PRAD	TCGA	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1389
p.S9828F	DO51362	PRAD	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.1389
p.M9559V	TCGA-KK-A6E8	PRAD	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.1667
p.M9559V	DO51364	PRAD	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.1667
p.V9545L	TCGA-KN-8425	KICH	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.V9545L	DO220474	KICH	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.2222
p.S924R	TCGA-L5-A4OI	ESCA	TCGA	ATSST	DEG_SPOP_SBC_1	922:926	Mutation altering degron motif	0.7427
p.L4460M	TCGA-L5-A4OJ	ESCA	TCGA	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1667
p.L4460M	DO52661	MALY	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1667
p.I5772S	TCGA-L5-A4ON	ESCA	TCGA	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1111
p.I5772S	DO233206	GACA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1111
p.F1762C	TCGA-L5-A4OT	ESCA	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.3056
p.F1762C	TCGA-L5-A4OT	ESCA	TCGA	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.1111
p.T7728S	TCGA-L5-A88Y	ESCA	TCGA	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation altering degron motif	0.7116
p.S302T	TCGA-L5-A88Y	ESCA	TCGA	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1944
p.L8325F	TCGA-L5-A8NQ	ESCA	TCGA	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.2222
p.T3458I	TCGA-L5-A8NR	ESCA	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation altering degron motif	0.7078
p.S11510P	TCGA-L5-A8NV	ESCA	TCGA	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation altering degron motif	0.6752
p.L8898F	TCGA-L9-A8F4	LUAD	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.1667
p.L8898F	DO49876	LUAD	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.1667
p.S7698T	TCGA-LA-A446	LUSC	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.25
p.S7698T	DO45450	LUSC	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.25
p.P7714S	TCGA-LB-A7SX	PAAD	TCGA	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.P7714S	DO49409	PAAD	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.0833
p.E3524K	TCGA-LI-A67I	SARC	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.0556
p.E3524K	DO220201	SARC	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.0556
p.P7524T	TCGA-LN-A7HW	ESCA	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation altering degron motif	0.7031
p.S5360F	TCGA-LP-A4AV	CESC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1389
p.S5360F	DO44275	CESC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1389
p.S5360F	ACH-001973	Metastasis	CCLE	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1389
p.S5334C	TCGA-LP-A4AV	CESC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S5334C	DO44275	CESC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S5174Y	TCGA-LP-A4AV	CESC	TCGA	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1667
p.S5174Y	DO44275	CESC	ICGC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1667
p.N2423T	TCGA-MI-A75C	LIHC	TCGA	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2222
p.N2423T	DO49705	LIHC	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2222
p.S2469Y	TCGA-MN-A4N1	LUAD	TCGA	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.1667
p.S2469Y	DO45328	LUAD	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.1667
p.V4927A	TCGA-MP-A4T6	LUAD	TCGA	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.V4927A	DO45395	LUAD	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1944
p.D7516N	TCGA-MP-A4TC	LUAD	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1667
p.D7516N	DO45342	LUAD	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1667
p.M7324I	TCGA-MT-A67F	HNSC	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.0833
p.M7324I	DO49070	HNSC	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.0833
p.M7324I	SIDM02050	Colorectal Carcinoma	GDSC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.0833
p.Y6316C	TCGA-MV-A51V	BLCA	TCGA	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1667
p.Y6316C	DO474	BLCA	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1667
p.S1157F	TCGA-MY-A913	CESC	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.2222
p.S1157F	DO49980	CESC	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.2222
p.S880F	TCGA-MY-A913	CESC	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1667
p.S880F	DO49980	CESC	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1667
p.S12F	TCGA-MY-A913	CESC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.9093
p.S12F	DO49980	CESC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.9093
p.S10L	TCGA-MY-A913	CESC	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8778
p.S10L	DO49980	CESC	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8778
p.K9544N	TCGA-N5-A4RT	UCS	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation substituting flanking lysine	0.3056
p.T5622A	TCGA-NC-A5HI	LUSC	TCGA	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7139
p.T5622A	DO45461	LUSC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7139
p.E878D	TCGA-ND-A4WC	UCS	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1111
p.P8776L	TCGA-OD-A75X	SKCM	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.7582
p.P8776L	TCGA-OD-A75X	SKCM	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7582
p.P8776L	TCGA-QC-A7B5	SARC	TCGA	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.7582
p.P8776L	TCGA-QC-A7B5	SARC	TCGA	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7582
p.P8776L	DO220239	SARC	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.7582
p.P8776L	DO220239	SARC	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7582
p.P8776L	DO48601	SKCM	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.7582
p.P8776L	DO48601	SKCM	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.7582
p.T10826M	TCGA-OR-A5J5	ACC	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.0556
p.T10826M	TCGA-VQ-A8P8	STAD	TCGA	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.0556
p.T10826M	DO230323	COCA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.0556
p.T10826M	DO51764	STAD	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.0556
p.S5357C	TCGA-OR-A5JB	ACC	TCGA	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.2222
p.T8997K	TCGA-OR-A5K8	ACC	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.25
p.S8099C	TCGA-OR-A5L6	ACC	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.643
p.T11966S	TCGA-OR-A5LD	ACC	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.0556
p.T11966S	SIDM01169	Ovarian Carcinoma	GDSC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.0556
p.T11966S	ACH-000885	Ovarian Cancer	CCLE	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.0556
p.T11966S	TOV-21G	ovary	COSMIC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.0556
p.S8065G	TCGA-OR-A5LR	ACC	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation altering degron motif	0.6993
p.T3223P	TCGA-PJ-A5Z9	KIRP	TCGA	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.1944
p.T3223P	DO44504	KIRP	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.1944
p.S11389L	TCGA-PK-A5HA	ACC	TCGA	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1667
p.T12509A	TCGA-PK-A5HB	ACC	TCGA	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.2778
p.T12509A	TCGA-PK-A5HB	ACC	TCGA	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.1111
p.P10329S	TCGA-PK-A5HC	ACC	TCGA	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.G5161E	TCGA-QB-AA9O	SKCM	TCGA	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.2778
p.G5161E	TCGA-QB-AA9O	SKCM	TCGA	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.25
p.G5161E	DO220874	MELA	ICGC	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.2778
p.G5161E	DO220874	MELA	ICGC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.25
p.G5161E	DO51267	SKCM	ICGC	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.2778
p.G5161E	DO51267	SKCM	ICGC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.25
p.A3973V	TCGA-QH-A6X4	LGG	TCGA	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.A3973V	DO50175	LGG	ICGC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.T11697A	TCGA-QK-A8Z9	HNSC	TCGA	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7139
p.T11697A	DO52098	HNSC	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7139
p.T11697A	ACH-000982	Colon/Colorectal Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7139
p.T11697A	ACH-001345	Colon/Colorectal Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7139
p.T11697A	GP5d	large intestine	COSMIC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation altering degron motif	0.7139
p.P1755S	TCGA-QQ-A5VD	SARC	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6752
p.P1755S	DO220252	SARC	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6752
p.D3529N	TCGA-QR-A6GW	PCPG	TCGA	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1944
p.M1492I	TCGA-QT-A5XO	PCPG	TCGA	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6507
p.T8966A	TCGA-R5-A7ZE	STAD	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.25
p.T8966A	DO222340	STAD	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.25
p.T8102P	TCGA-R5-A805	STAD	TCGA	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.7031
p.T8102P	DO222346	STAD	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.7031
p.S302L	TCGA-RA-A741	CESC	TCGA	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1944
p.S302L	DO49013	CESC	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1944
p.S10023F	TCGA-RP-A693	SKCM	TCGA	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023F	DO51268	SKCM	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023F	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023F	COLO-680N	oesophagus	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.G11243R	TCGA-RP-A694	SKCM	TCGA	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.3056
p.G11243R	DO51269	SKCM	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.3056
p.A11306V	TCGA-RP-A695	SKCM	TCGA	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.5825
p.A11306V	DO51270	SKCM	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.5825
p.S8066C	TCGA-S5-A6DX	BLCA	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation blocking phosphorylation signal	0.75
p.S8066C	DO51903	BLCA	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation blocking phosphorylation signal	0.75
p.D7805E	TCGA-S5-A6DX	BLCA	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.25
p.D7805E	DO51903	BLCA	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.25
p.D3468E	TCGA-UB-A7MB	LIHC	TCGA	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1111
p.D3468E	DO52318	LIHC	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1111
p.T8906I	TCGA-UY-A9PA	BLCA	TCGA	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation altering degron motif	0.7078
p.T8906I	DO219040	BLCA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation altering degron motif	0.7078
p.T8906I	SIDM01277	Esophageal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation altering degron motif	0.7078
p.S10861A	TCGA-UZ-A9PS	KIRP	TCGA	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6477
p.S10861A	TCGA-UZ-A9PS	KIRP	TCGA	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7588
p.S10861A	DO219709	KIRP	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6477
p.S10861A	DO219709	KIRP	ICGC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7588
p.S10861A	NEC8	testis	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6477
p.S10861A	NEC8	testis	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7588
p.S10861A	CML-T1	haematopoietic and lymphoid tissue	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6477
p.S10861A	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7588
p.S10861A	NKM-1	haematopoietic and lymphoid tissue	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6477
p.S10861A	NKM-1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7588
p.I11946M	TCGA-VB-A8QN	DLBC	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.2222
p.I11946M	DO223730	DLBC	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.2222
p.S11083P	TCGA-VQ-A8DU	STAD	TCGA	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.5641
p.S11083P	DO51752	STAD	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.5641
p.L11877V	TCGA-VQ-A8P2	STAD	TCGA	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.2778
p.L11877V	TCGA-VQ-A8P2	STAD	TCGA	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1389
p.L11877V	DO51761	STAD	ICGC	ATSSS	DEG_SPOP_SBC_1	11879:11883	Mutation rewiring degron network	0.2778
p.L11877V	DO51761	STAD	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1389
p.T7325I	TCGA-VQ-A8P2	STAD	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation blocking phosphorylation signal	0.5556
p.T7325I	DO51761	STAD	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation blocking phosphorylation signal	0.5556
p.T4600I	TCGA-VQ-A8PE	STAD	TCGA	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.25
p.T4600I	DO51769	STAD	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.25
p.S5641P	TCGA-VQ-A8PO	STAD	TCGA	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.25
p.S5641P	DO233882	GACA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.25
p.S5641P	DO51773	STAD	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.25
p.R5084H	TCGA-VQ-A924	STAD	TCGA	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.1944
p.R5084H	DO51795	STAD	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.1944
p.P7536Q	TCGA-VS-A8EI	CESC	TCGA	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.0833
p.P7536Q	DO51621	CESC	ICGC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.0833
p.S8081C	TCGA-VS-A94X	CESC	TCGA	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.1389
p.S8081C	DO51632	CESC	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.1389
p.P12984S	TCGA-VS-A9U5	CESC	TCGA	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.6752
p.P12984S	TCGA-VS-A9U5	CESC	TCGA	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.6752
p.P12984S	DO51641	CESC	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.6752
p.P12984S	DO51641	CESC	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.6752
p.P12984S	SIDM01198	Burkitt's Lymphoma	GDSC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.6752
p.P12984S	SIDM01198	Burkitt's Lymphoma	GDSC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.6752
p.P12984S	ACH-000567	Lymphoma	CCLE	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.6752
p.P12984S	ACH-000567	Lymphoma	CCLE	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.6752
p.P12984S	ST486	haematopoietic and lymphoid tissue	COSMIC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.6752
p.P12984S	ST486	haematopoietic and lymphoid tissue	COSMIC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.6752
p.T11584N	TCGA-VS-A9U5	CESC	TCGA	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7055
p.T11584N	DO51641	CESC	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7055
p.P1758S	TCGA-VS-A9UC	CESC	TCGA	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6752
p.P1758S	DO219732	CESC	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6752
p.P1758S	ACH-001647	Leukemia	CCLE	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.6752
p.S892F	TCGA-W3-A825	SKCM	TCGA	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.6871
p.S892F	DO51272	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.6871
p.S8279F	TCGA-W3-AA1O	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.2778
p.S8279F	DO51274	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.2778
p.T5458I	TCGA-W3-AA1O	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1667
p.T5458I	DO51274	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1667
p.S7801F	TCGA-W3-AA1Q	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.1389
p.S7801F	DO219487	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.1389
p.G11959E	TCGA-W3-AA1V	SKCM	TCGA	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.25
p.G11959E	DO229456	SKCA	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.25
p.G11959E	DO51276	SKCM	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.25
p.P7333S	TCGA-W3-AA1V	SKCM	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6752
p.P7333S	DO229446	SKCA	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6752
p.P7333S	DO51276	SKCM	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6752
p.P6061L	TCGA-W3-AA1V	SKCM	TCGA	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2222
p.P6061L	DO51276	SKCM	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2222
p.P3289L	TCGA-W3-AA1V	SKCM	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P3289L	DO51276	SKCM	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P1819S	TCGA-W3-AA1V	SKCM	TCGA	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.6752
p.P1819S	DO51276	SKCM	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.6752
p.E9541K	TCGA-W3-AA1W	SKCM	TCGA	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.1111
p.E9541K	DO51277	SKCM	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.1111
p.G3299E	TCGA-W3-AA21	SKCM	TCGA	NLYSGTP	CBL_PTK	3295:3301	Mutation altering degron motif	0.6087
p.G3299E	DO51278	SKCM	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation altering degron motif	0.6087
p.P8968S	TCGA-WB-A820	PCPG	TCGA	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.3056
p.P12203L	TCGA-WE-A8K4	SKCM	TCGA	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7582
p.P12203L	DO51281	SKCM	ICGC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7582
p.S11105F	TCGA-WE-A8K4	SKCM	TCGA	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2778
p.S11105F	TCGA-WE-A8K4	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.2778
p.S11105F	DO51281	SKCM	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.2778
p.S11105F	DO51281	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.2778
p.M8994I	TCGA-WE-A8K5	SKCM	TCGA	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1667
p.M8994I	DO51282	SKCM	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1667
p.S13154F	TCGA-WE-A8ZM	SKCM	TCGA	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6871
p.S13154F	DO51284	SKCM	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation altering degron motif	0.6871
p.D10427N	TCGA-WE-A8ZO	SKCM	TCGA	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1111
p.D10427N	DO219878	SKCA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1111
p.D10427N	DO51286	SKCM	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1111
p.S11174F	TCGA-WE-A8ZX	SKCM	TCGA	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0833
p.S11174F	TCGA-WE-A8ZX	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.25
p.S11174F	DO51291	SKCM	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0833
p.S11174F	DO51291	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.25
p.D2919A	TCGA-WE-AAA0	SKCM	TCGA	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1667
p.D2919A	DO51294	SKCM	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.1667
p.E316K	TCGA-WE-AAA4	SKCM	TCGA	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7022
p.E316K	DO51296	SKCM	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7022
p.P11293S	TCGA-WS-AB45	COAD	TCGA	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.P11293S	DO51734	COAD	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.1111
p.P1442S	TCGA-WY-A859	LGG	TCGA	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.25
p.P1442S	DO219859	LGG	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.25
p.G7774W	TCGA-XF-A8HG	BLCA	TCGA	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.25
p.G7774W	DO49802	BLCA	ICGC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.25
p.T8689R	TCGA-XF-A9T3	BLCA	TCGA	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7876
p.T8689R	DO51922	BLCA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7876
p.S13911R	TCGA-XK-AAIW	PRAD	TCGA	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911R	DO51407	PRAD	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.V1103I	TCGA-XU-A92Z	THYM	TCGA	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S1008F	TCGA-XV-AAZY	SKCM	TCGA	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.7982
p.S1008F	DO218884	SKCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.7982
p.S1008F	DO219497	SKCM	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.7982
p.G3560S	TCGA-YC-A89H	BLCA	TCGA	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2222
p.G3560S	DO51948	BLCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2222
p.S11182L	TCGA-YD-A89C	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.3056
p.S11182L	DO219501	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.3056
p.P2995S	TCGA-YD-A89C	SKCM	TCGA	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995S	DO219501	SKCM	ICGC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995S	SIDM00007	Other Solid Cancers	GDSC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995S	ACH-001550	Skin Cancer	CCLE	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995S	MCC13	skin	COSMIC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.T1861I	TCGA-YD-A89C	SKCM	TCGA	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.1667
p.T1861I	DO219501	SKCM	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.1667
p.S21N	TCGA-YD-A89C	SKCM	TCGA	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.0833
p.S21N	DO219501	SKCM	ICGC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.0833
p.P8280L	TCGA-YD-A9TA	SKCM	TCGA	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.25
p.P8280L	DO219503	SKCM	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.25
p.V8058L	TCGA-YD-A9TA	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.25
p.V8058L	DO219503	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.25
p.S7491F	TCGA-YD-A9TA	SKCM	TCGA	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.S7491F	DO219503	SKCM	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.G224E	TCGA-YD-A9TB	SKCM	TCGA	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.G224E	DO23154	LINC	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.G224E	DO45085	LINC	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.G224E	DO51297	SKCM	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.0833
p.S5815F	TCGA-YG-AA3O	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.1944
p.S5815F	TCGA-YG-AA3O	SKCM	TCGA	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2222
p.S5815F	DO51299	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.1944
p.S5815F	DO51299	SKCM	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2222
p.P1163S	TCGA-YG-AA3O	SKCM	TCGA	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.6752
p.P1163S	DO51299	SKCM	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.6752
p.E9530Q	TCGA-YY-A8LH	PAAD	TCGA	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.E9530Q	DO50273	PAAD	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.D11374N	TCGA-Z2-A8RT	SKCM	TCGA	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1944
p.D11374N	DO51301	SKCM	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1944
p.P2324L	TCGA-Z2-A8RT	SKCM	TCGA	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.6471
p.P2324L	DO51301	SKCM	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.6471
p.E7338K	TCGA-ZF-A9R2	BLCA	TCGA	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.3056
p.E7338K	DO219058	BLCA	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation rewiring degron network	0.3056
p.T346I	TCGA-ZF-A9RC	BLCA	TCGA	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2222
p.T346I	DO219068	BLCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.2222
p.E1186K	TCGA-ZF-A9RG	BLCA	TCGA	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.0556
p.E1186K	DO219076	BLCA	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.0556
p.K975N	TCGA-ZF-AA4V	BLCA	TCGA	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation substituting flanking lysine	0.1944
p.K975N	DO219087	BLCA	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation substituting flanking lysine	0.1944
p.T2506A	DO48361	BLCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO229010	COCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO229016	COCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO229003	COCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO229005	COCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO234285	ESAD	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO230942	LUSC	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.T2506A	DO52365	LUSC	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.2778
p.P5654H	DO548	BLCA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.A11074T	DO894	BOCA	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation rewiring degron network	0.1667
p.S9481N	DO233955	BPLL	ICGC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation rewiring degron network	0.25
p.S10020F	DO225198	BRCA	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.P312L	DO225258	BRCA	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.6471
p.S6060T	DO225360	BRCA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.25
p.G13906D	DO225389	BRCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1389
p.L4779V	DO224732	BRCA	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.5654
p.I11493T	DO224852	BRCA	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.0556
p.I11493T	DO52550	BRCA	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.0556
p.P11527S	DO224904	BRCA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1944
p.T545A	DO228483	BRCA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO229010	COCA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO229013	COCA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO230529	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO52365	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO231078	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO231007	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.T545A	DO231022	LUSC	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.2222
p.R344K	DO228483	BRCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1667
p.R344K	DO229010	COCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1667
p.R344K	DO229013	COCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1667
p.R344K	DO230550	LUSC	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1667
p.R344K	DO52365	LUSC	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1667
p.A11081V	DO222404	BTCA	ICGC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.5825
p.T11007N	DO222857	BTCA	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.1667
p.S11104N	DO222990	BTCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO222990	BTCA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO229010	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO229010	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO229016	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO229016	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO229005	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO229005	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO228957	LICA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO228957	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO230542	LUSC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO230542	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.S11104N	DO52365	LUSC	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation rewiring degron network	0.3056
p.S11104N	DO52365	LUSC	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.V3530I	DO222990	BTCA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.V3530I	DO230334	COCA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.V3530I	DO229013	COCA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.V3530I	DO229505	LAML	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.V3530I	DO228941	LICA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.V3530I	DO231102	LUSC	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.L464I	DO52699	CLLE	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1944
p.S1746R	DO223552	CLLE	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.0833
p.S1746R	DO223552	CLLE	ICGC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.2222
p.S11056R	DO223542	CLLE	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.S4607N	DO6416	CLLE	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.5958
p.F1171S	DO6540	CLLE	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1944
p.E969D	DO8898	COAD	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.25
p.N5228K	DO8898	COAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.5806
p.T5468I	DO230309	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation altering degron motif	0.7078
p.R3573H	DO230334	COCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO229013	COCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO234216	ESAD	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO229505	LAML	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO228941	LICA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO230929	LUSC	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.R3573H	DO230974	LUSC	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.2778
p.H9513Q	DO230334	COCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513Q	DO227999	COCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513Q	DO229003	COCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513Q	DO229505	LAML	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.H9513Q	DO230529	LUSC	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0556
p.Y6587C	DO230334	COCA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.0556
p.S12514T	DO230334	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO229010	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO229016	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO229003	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO229005	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO228941	LICA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.S12514T	DO228957	LICA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.7116
p.I4034F	DO230334	COCA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.I4034F	DO229013	COCA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.I4034F	DO229480	LAML	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.I4034F	DO229505	LAML	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.I4034F	DO228941	LICA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.I4034F	DO231049	LUSC	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.0833
p.T3723M	DO230334	COCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.T3723M	DO229013	COCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.T3723M	DO229003	COCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.T3723M	DO229480	LAML	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.T3723M	DO229505	LAML	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.T3723M	DO228941	LICA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7423
p.V8217M	DO230343	COCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.25
p.T8679I	DO228935	COCA	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation altering degron motif	0.7078
p.V6306M	DO227709	COCA	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO227999	COCA	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO229003	COCA	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO229489	LAML	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO229505	LAML	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO23166	LINC	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.V6306M	DO231056	LUSC	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation altering degron motif	0.7208
p.A3569T	DO227634	COCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6028
p.S2463L	DO227870	COCA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S2463L	SIDM00967	Ovarian Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S2463L	SIDM01133	Other Solid Cancers	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S2463L	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S2463L	SIDM00720	Mesothelioma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S2463L	SIDM01409	Bladder Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7667
p.S302A	DO227995	COCA	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1944
p.P8789R	DO227999	COCA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	DO227999	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	DO229003	COCA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	DO229003	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	DO230659	LAML	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	DO230659	LAML	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	DO231140	LAML	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	DO231140	LAML	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	DO230529	LUSC	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	DO230529	LUSC	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01034	B-Lymphoblastic Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01034	B-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00570	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00570	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00215	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00215	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00557	Neuroblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00557	Neuroblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00322	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00434	Plasma Cell Myeloma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00434	Plasma Cell Myeloma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00437	Acute Myeloid Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00437	Acute Myeloid Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00578	Neuroblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00578	Neuroblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00617	Hepatocellular Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00617	Hepatocellular Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00075	Non-Cancerous	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00075	Non-Cancerous	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00614	Hepatocellular Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00614	Hepatocellular Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00513	Non-Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00513	Non-Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00352	Ovarian Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00352	Ovarian Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00584	Osteosarcoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00584	Osteosarcoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01199	Hepatocellular Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01199	Hepatocellular Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00291	Melanoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00291	Melanoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00315	Glioblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00315	Glioblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01005	Acute Myeloid Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01005	Acute Myeloid Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00569	Osteosarcoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00569	Osteosarcoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00193	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00193	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00267	Biliary Tract Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00267	Biliary Tract Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00590	Oral Cavity Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00590	Oral Cavity Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00465	Ovarian Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00465	Ovarian Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00581	Glioblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00581	Glioblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00293	Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00293	Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00457	Plasma Cell Myeloma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00457	Plasma Cell Myeloma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00060	Ovarian Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00060	Ovarian Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00364	B-Lymphoblastic Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00364	B-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00568	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00568	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00556	Neuroblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00556	Neuroblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00235	Kidney Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00235	Kidney Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00487	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00487	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00294	Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00294	Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00564	Ovarian Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00564	Ovarian Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00498	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00498	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00567	Other Solid Cancers	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00567	Other Solid Cancers	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00240	Cervical Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00240	Cervical Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00612	Glioma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00612	Glioma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00357	Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00357	Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01019	Acute Myeloid Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01019	Acute Myeloid Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00347	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00347	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00245	Small Cell Lung Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00245	Small Cell Lung Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00283	B-Cell Non-Hodgkin's Lymphoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00283	B-Cell Non-Hodgkin's Lymphoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00280	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00280	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00549	B-Lymphoblastic Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00549	B-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00271	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00271	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00469	Pancreatic Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00469	Pancreatic Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00560	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00560	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00326	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00326	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00380	Acute Myeloid Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00380	Acute Myeloid Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01025	Esophageal Squamous Cell Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01025	Esophageal Squamous Cell Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00233	T-Lymphoblastic Leukemia	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00233	T-Lymphoblastic Leukemia	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00302	Other Solid Cancers	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00302	Other Solid Cancers	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01018	Hodgkin's Lymphoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01018	Hodgkin's Lymphoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00412	B-Cell Non-Hodgkin's Lymphoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00412	B-Cell Non-Hodgkin's Lymphoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00026	Other Solid Cancers	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00026	Other Solid Cancers	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01728	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01728	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01609	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01609	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01608	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01608	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01659	Kidney Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01659	Kidney Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01617	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01617	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00168	Head and Neck Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00168	Head and Neck Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01412	Oral Cavity Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01412	Oral Cavity Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00169	Head and Neck Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00169	Head and Neck Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01770	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01770	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01622	Breast Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01622	Breast Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01377	Ovarian Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01377	Ovarian Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01336	Glioblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01336	Glioblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01432	Kidney Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01432	Kidney Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00784	Glioma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00784	Glioma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01575	Plasma Cell Myeloma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01575	Plasma Cell Myeloma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01658	Unknown	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01658	Unknown	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00500	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00500	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00171	Colorectal Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00171	Colorectal Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01774	Pancreatic Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01774	Pancreatic Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM00016	Neuroblastoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM00016	Neuroblastoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01434	Hepatocellular Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01434	Hepatocellular Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01729	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01729	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01619	Endometrial Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01619	Endometrial Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.P8789R	SIDM01443	Gastric Carcinoma	GDSC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.0556
p.P8789R	SIDM01443	Gastric Carcinoma	GDSC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.K9429N	DO227999	COCA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation substituting flanking lysine	0.2222
p.K9429N	DO224739	COCA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation substituting flanking lysine	0.2222
p.K9429N	DO229003	COCA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation substituting flanking lysine	0.2222
p.K9429N	DO229489	LAML	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation substituting flanking lysine	0.2222
p.K9429N	DO229505	LAML	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation substituting flanking lysine	0.2222
p.I8200T	DO227999	COCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1389
p.I8200T	DO229003	COCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1389
p.I8200T	DO230659	LAML	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1389
p.I8200T	DO231140	LAML	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1389
p.V11097M	DO227999	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.6097
p.V11097M	DO229003	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.6097
p.V11097M	DO229005	COCA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.6097
p.V11097M	DO229505	LAML	ICGC	VVTPLVT	DEG_SCF_FBW7_1	11097:11103	Mutation altering degron motif	0.6097
p.S10912R	DO227999	COCA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0833
p.S10912R	DO229003	COCA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0833
p.S10912R	DO229489	LAML	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0833
p.S10912R	DO229505	LAML	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.0833
p.R3417Q	DO227999	COCA	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.R3417Q	DO229003	COCA	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.R3417Q	DO229489	LAML	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.R3417Q	DO229505	LAML	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.R3417Q	DO231091	LUSC	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.R3417Q	DO231120	LUSC	ICGC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1944
p.T11744N	DO224668	COCA	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.0556
p.T11744N	DO224668	COCA	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.1111
p.T13908N	DO224801	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1944
p.H13909P	DO224801	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2222
p.P192S	DO222501	COCA	ICGC	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation rewiring degron network	0.0556
p.L7720R	DO222565	COCA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	DO234328	ESAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	DO234289	ESAD	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	DO222702	MELA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	SIDM00611	Kidney Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	ACH-000684	Kidney Cancer	CCLE	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.L7720R	KMRC-1	kidney	COSMIC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.S8053P	DO222762	COCA	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.1111
p.F11708L	DO222762	COCA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.0833
p.T3112M	DO222762	COCA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.3056
p.H9522R	DO222762	COCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.3056
p.S6896Y	DO222762	COCA	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.S6896Y	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.S6896Y	SIDM00454	Rhabdomyosarcoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.S6896Y	SIDM00673	Breast Carcinoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.S6896Y	SIDM00808	Burkitt's Lymphoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.S6896Y	SIDM01254	Burkitt's Lymphoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.L9266I	DO222762	COCA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation altering degron motif	0.6063
p.L9266I	DO222762	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation altering degron motif	0.6063
p.S880Y	DO222762	COCA	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1667
p.S9465Y	DO222798	COCA	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.0556
p.A889V	DO222864	COCA	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.5825
p.S11984G	DO222874	COCA	ICGC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.2222
p.Q5476H	DO222884	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.1111
p.S9822Y	DO222884	COCA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.3056
p.S11248Y	DO222884	COCA	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6009
p.T8767M	DO52485	COCA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.T8767M	DO52485	COCA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.T8767M	DO234336	ESAD	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.T8767M	DO234336	ESAD	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.T8767M	DO233210	GACA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.T8767M	DO233210	GACA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.0833
p.T11163I	DO222800	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation altering degron motif	0.7078
p.V9514I	DO222849	COCA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.0833
p.N5228I	DO229010	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6169
p.N5228I	DO229013	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6169
p.N5228I	DO229016	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6169
p.N5228I	DO229003	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6169
p.N5228I	DO229005	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6169
p.R1015G	DO229010	COCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO229016	COCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO229003	COCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO229005	COCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO234205	ESAD	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO234285	ESAD	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.R1015G	DO52365	LUSC	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1389
p.V8969M	DO229010	COCA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.V8969M	DO229016	COCA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.V8969M	DO229003	COCA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.V8969M	DO229005	COCA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.V8969M	DO234285	ESAD	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.V8969M	DO52365	LUSC	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7208
p.P3289T	DO229010	COCA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P3289T	DO229016	COCA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P3289T	DO229005	COCA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P3289T	DO234285	ESAD	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.P3289T	DO52365	LUSC	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1667
p.T1162I	DO229010	COCA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO229016	COCA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO229003	COCA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO229005	COCA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO234205	ESAD	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO234285	ESAD	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.T1162I	DO52365	LUSC	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7078
p.L1833F	DO229010	COCA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO229010	COCA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO229016	COCA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO229016	COCA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO229003	COCA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO229003	COCA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO229005	COCA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO229005	COCA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO234285	ESAD	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO234285	ESAD	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO229047	LICA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO229047	LICA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.L1833F	DO52365	LUSC	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.3056
p.L1833F	DO52365	LUSC	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1389
p.I5751T	DO229010	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0833
p.I5751T	DO229013	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0833
p.I5751T	DO229016	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0833
p.I5751T	DO229003	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0833
p.I5751T	DO229005	COCA	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0833
p.T7276S	DO229010	COCA	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1389
p.T7276S	SIDM00533	Pancreatic Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1389
p.T7276S	SIDM00562	Breast Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1389
p.T7276S	SIDM00448	B-Cell Non-Hodgkin's Lymphoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1389
p.T7276S	SIDM00163	Biliary Tract Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.1389
p.S11585R	DO229010	COCA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.S11585R	DO229016	COCA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.S11585R	DO229005	COCA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.S11585R	DO234205	ESAD	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.S11585R	DO234285	ESAD	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.S11585R	DO52365	LUSC	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.7427
p.P4458L	DO229010	COCA	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458L	DO229016	COCA	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458L	DO229005	COCA	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458L	DO234285	ESAD	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458L	DO52365	LUSC	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.G12525A	DO229013	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.0556
p.G12525A	DO229013	COCA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2222
p.D12523H	DO229013	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.1111
p.D12523H	DO229013	COCA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2778
p.D12523H	DO229005	COCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.1111
p.D12523H	DO229005	COCA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2778
p.P13611S	DO229013	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.1944
p.P13611S	DO229003	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.1944
p.P13611S	DO229005	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.1944
p.P13611S	DO220873	MELA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.1944
p.P10828S	DO229013	COCA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.1111
p.S11154F	DO229013	COCA	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1389
p.T10030K	DO229016	COCA	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation altering degron motif	0.7306
p.V13167M	DO229003	COCA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.1111
p.T10665S	DO229003	COCA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1111
p.I13607T	DO229005	COCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.3056
p.I13607T	DO229052	LICA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.3056
p.T11388S	DO228111	EOPC	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1389
p.Q3469K	DO228126	EOPC	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.0833
p.F10954L	DO227451	EOPC	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1389
p.F10954L	DO228579	GACA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1389
p.F10954L	DO233286	GACA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1389
p.F10954L	DO228921	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1389
p.F10954L	DO228899	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.1389
p.L10956P	DO227451	EOPC	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0833
p.L10956P	DO234333	ESAD	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0833
p.L10956P	DO228921	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0833
p.L10956P	DO228899	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0833
p.L12366R	DO50411	ESAD	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.L12366R	DO50411	ESAD	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.25
p.L3113I	DO50412	ESAD	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.6063
p.A5754V	DO50402	ESAD	ICGC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.I5082T	DO50374	ESAD	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.1389
p.S10832I	DO50354	ESAD	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.2222
p.E5818A	DO50357	ESAD	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.1111
p.E5818A	DO50357	ESAD	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.3056
p.A1504T	DO50349	ESAD	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.1667
p.A10547E	DO50342	ESAD	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.7701
p.A12044V	DO50337	ESAD	ICGC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation altering degron motif	0.5825
p.I5233L	DO50325	ESAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.2778
p.P12048L	DO50328	ESAD	ICGC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation altering degron motif	0.7582
p.S11056G	DO234212	ESAD	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.T6329R	DO234231	ESAD	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2222
p.L1154V	DO234233	ESAD	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1389
p.L1154V	DO228761	GACA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1389
p.L1154V	DO233718	GACA	ICGC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation rewiring degron network	0.1389
p.R13910Q	DO234257	ESAD	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.25
p.R13910Q	ACH-000117	Breast Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.25
p.R13910Q	ACH-000590	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.25
p.R13910Q	ACH-000638	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.25
p.R13910Q	ACH-000666	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.25
p.P10040L	DO234262	ESAD	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.P10040L	SIDM00683	Prostate Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.P10040L	SIDM00839	Colorectal Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.P10040L	LoVo	large intestine	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.P10040L	LNCaP-Clone-FGC	prostate	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1111
p.T12983N	DO234269	ESAD	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7055
p.T12983N	DO234269	ESAD	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation altering degron motif	0.7055
p.S9444T	DO234270	ESAD	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.2222
p.S9444T	DO234270	ESAD	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.25
p.M11151V	DO234188	ESAD	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.M8093T	DO234321	ESAD	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8093T	DO234321	ESAD	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1944
p.S3539T	DO234353	ESAD	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.6005
p.T8096S	DO234367	ESAD	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.2222
p.T8096S	DO234367	ESAD	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2778
p.T5826S	DO234363	ESAD	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.25
p.L9436R	DO234363	ESAD	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.3056
p.E711D	DO234363	ESAD	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1111
p.N3226H	DO234363	ESAD	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.T6490M	DO234380	ESAD	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.7423
p.I5233S	DO234449	ESAD	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.2778
p.T11252P	DO234449	ESAD	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.7031
p.F11391V	DO234400	ESAD	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.2222
p.G9454V	DO234414	ESAD	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation altering degron motif	0.6421
p.S8099P	DO234413	ESAD	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.5641
p.S2899G	DO234422	ESAD	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation altering degron motif	0.6993
p.T9819S	DO234422	ESAD	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation altering degron motif	0.6005
p.A8170S	DO48296	ESCA	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.1111
p.A8170S	DO48296	ESCA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1667
p.I364M	DO48270	ESCA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.1111
p.S7112P	DO48219	ESCA	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.6752
p.E8993Q	DO48210	ESCA	ICGC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.D12523G	DO48194	ESCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.1111
p.D12523G	DO48194	ESCA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2778
p.R5610Q	DO48195	ESCA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0556
p.R5610Q	DO228933	LICA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0556
p.D4944Y	DO223003	ESCA	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.1111
p.T10764M	DO223138	ESCA	ICGC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.0556
p.K2903R	DO223149	ESCA	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation substituting flanking lysine	0.3611
p.K2903R	DO223149	ESCA	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation substituting flanking lysine	0.3333
p.E11188Q	DO223057	ESCA	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1389
p.E297D	DO222482	ESCA	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.0556
p.E297D	SIDM00681	Colorectal Carcinoma	GDSC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.0556
p.E297D	ACH-000252	Colon/Colorectal Cancer	CCLE	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.0556
p.E297D	LS-1034	large intestine	COSMIC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.0556
p.S8190R	DO222444	ESCA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0556
p.S8190R	DO229253	THCA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0556
p.G4602E	DO222607	ESCA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.3056
p.R8310S	DO228542	GACA	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.D3731A	DO228769	GACA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2222
p.L12524P	DO218136	GACA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.0833
p.L12524P	DO218136	GACA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.25
p.S502C	DO233034	GACA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation blocking phosphorylation signal	0.6111
p.S5334P	DO233154	GACA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S5334P	SIDM00777	Colorectal Carcinoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S5334P	ACH-000360	Colon/Colorectal Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S5334P	NCI-H508	large intestine	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.S1748R	DO233168	GACA	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.1389
p.S1748R	DO233168	GACA	ICGC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.2778
p.P563S	DO233168	GACA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.P563S	ACH-000987	Skin Cancer	CCLE	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.P563S	Mewo	skin	COSMIC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.S6602Y	DO233166	GACA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.3056
p.N4861I	DO233166	GACA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.3056
p.T8971P	DO233171	GACA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7031
p.L365R	DO233170	GACA	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.0833
p.T8691P	DO233170	GACA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7031
p.T8691P	DO49418	PACA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7031
p.A1665T	DO233239	GACA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.25
p.A1658S	DO233273	GACA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation altering degron motif	0.7588
p.M6047I	DO233277	GACA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1667
p.N11499T	DO233206	GACA	ICGC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2222
p.P13168Q	DO233207	GACA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.0833
p.P8692T	DO233221	GACA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.3056
p.T3909M	DO233195	GACA	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T3909M	SIDM00487	Colorectal Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T3909M	SIDM01618	B-Lymphoblastic Leukemia	GDSC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T3909M	ACH-000942	Leukemia	CCLE	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T3909M	ACH-000963	Colon/Colorectal Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T3909M	CCK-81	large intestine	COSMIC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation blocking phosphorylation signal	0.5556
p.T513P	DO233634	GACA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.3056
p.T7812P	DO233646	GACA	ICGC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation altering degron motif	0.7031
p.L7720P	DO233679	GACA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1944
p.T463P	DO233680	GACA	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2222
p.T12368P	DO233688	GACA	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation blocking phosphorylation signal	0.6389
p.T3563S	DO233692	GACA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.3056
p.R3221S	DO233751	GACA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.1389
p.V7696L	DO233754	GACA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.P1017Q	DO233767	GACA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.0833
p.P157T	DO233767	GACA	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.2778
p.P157T	DO229027	LICA	ICGC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.2778
p.P11951S	DO233767	GACA	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation altering degron motif	0.5641
p.S8782A	DO233765	GACA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation blocking phosphorylation signal	0.6944
p.S8782A	DO233765	GACA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation blocking phosphorylation signal	0.7222
p.P5807L	DO233764	GACA	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation altering degron motif	0.6471
p.A3715S	DO233779	GACA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.1667
p.P9445T	DO233783	GACA	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation rewiring degron network	0.25
p.P9445T	DO233783	GACA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation rewiring degron network	0.2222
p.T11376K	DO233704	GACA	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.1389
p.L12366P	DO233749	GACA	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.L12366P	DO233749	GACA	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.25
p.L12366F	DO233749	GACA	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0833
p.L12366F	DO233749	GACA	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.25
p.E11583K	DO233746	GACA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation altering degron motif	0.591
p.T966I	DO233888	GACA	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation altering degron motif	0.7078
p.S9738P	DO233804	GACA	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.7863
p.G11807A	DO233804	GACA	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.3056
p.N1724T	DO233814	GACA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1667
p.R2736W	DO233833	GACA	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1111
p.N10700I	DO233859	GACA	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1111
p.P3568T	DO233916	GACA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.7031
p.E8918K	DO233921	GACA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.0556
p.E878K	DO233935	GACA	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1111
p.A9520S	DO233941	GACA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.T4933I	DO11854	GBM	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation altering degron motif	0.5966
p.T3110I	DO229505	LAML	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.25
p.T3110I	SIDM00217	Colorectal Carcinoma	GDSC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.25
p.T3110I	SNU-1040	large intestine	COSMIC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.25
p.S8980Y	DO230659	LAML	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	DO231140	LAML	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	SIDM00305	Ovarian Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	SIDM00383	Gastric Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	JHOS-2	ovary	COSMIC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	SCH	stomach	COSMIC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.S8980Y	LU-65	lung	COSMIC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1389
p.P8176S	DO228196	LICA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation altering degron motif	0.6752
p.F12002L	DO228202	LICA	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation altering degron motif	0.587
p.L7707Q	DO228202	LICA	ICGC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.2778
p.L12991F	DO228202	LICA	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.2222
p.L12991F	DO228202	LICA	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1111
p.L12991F	DO228202	LICA	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.25
p.L10655Q	DO231992	LICA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation altering degron motif	0.6654
p.I1980T	DO228374	LICA	ICGC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.R5084L	DO231947	LICA	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.1944
p.I4464K	DO228555	LICA	ICGC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.2778
p.Q3111L	DO228743	LICA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.P2405Q	DO228929	LICA	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.0556
p.E10403V	DO228934	LICA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1667
p.V1851A	DO228941	LICA	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation altering degron motif	0.5825
p.T211N	DO228940	LICA	ICGC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.8166
p.T11576M	DO228947	LICA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1667
p.T11576M	SIDM00057	Neuroblastoma	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1667
p.T11576M	SIDM00552	Rhabdomyosarcoma	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1667
p.T11576M	KYM-1	soft tissue	COSMIC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1667
p.L13615M	DO228948	LICA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.0833
p.T4930K	DO228948	LICA	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.2778
p.P1819Q	DO228948	LICA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.7035
p.P457T	DO228948	LICA	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation altering degron motif	0.7031
p.T8102N	DO228952	LICA	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation altering degron motif	0.7055
p.L2914M	DO228866	LICA	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation rewiring degron network	0.3056
p.E10915A	DO228899	LICA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1667
p.L11003I	DO228960	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.2778
p.L11003I	DO229030	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.2778
p.S964R	DO228974	LICA	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation altering degron motif	0.8538
p.P11953T	DO228976	LICA	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation altering degron motif	0.7031
p.P10922T	DO228976	LICA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.5919
p.T2522K	DO228976	LICA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.0556
p.T1767K	DO228976	LICA	ICGC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.1667
p.T10682K	DO228978	LICA	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1667
p.H705N	DO228978	LICA	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.2778
p.T12825N	DO228971	LICA	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.7055
p.T12825N	DO229036	LICA	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.7055
p.T5147K	DO228971	LICA	ICGC	VITTT	DEG_SPOP_SBC_1	5155:5159	Mutation rewiring degron network	0.1111
p.A1458E	DO228971	LICA	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.3056
p.T10665K	DO228985	LICA	ICGC	LTPLVT	DEG_SCF_FBW7_1	10652:10657	Mutation rewiring degron network	0.1111
p.T1459K	DO228986	LICA	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.2778
p.T11055K	DO228981	LICA	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1944
p.I10921L	DO232020	LICA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation altering degron motif	0.6063
p.T12526N	DO229018	LICA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.1944
p.T12006N	DO229018	LICA	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation altering degron motif	0.5944
p.P10866T	DO229018	LICA	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7031
p.P10866T	DO229018	LICA	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation altering degron motif	0.5919
p.S8327R	DO229018	LICA	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1667
p.S3298Y	DO229018	LICA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation altering degron motif	0.712
p.P11429Q	DO229018	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7035
p.T8090N	DO229018	LICA	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation altering degron motif	0.7055
p.P11527T	DO229019	LICA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1944
p.T2087K	DO229019	LICA	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation altering degron motif	0.7306
p.P1721T	DO229019	LICA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.0833
p.P10833T	DO229015	LICA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.A3309D	DO229015	LICA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1111
p.T3120N	DO229015	LICA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.7055
p.T11536K	DO229029	LICA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation altering degron motif	0.7306
p.T10867N	DO229029	LICA	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.8166
p.T10867N	DO229029	LICA	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation altering degron motif	0.8166
p.T8779K	DO229029	LICA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation altering degron motif	0.8417
p.T8779K	DO229029	LICA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation altering degron motif	0.8417
p.P7492H	DO229029	LICA	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1667
p.P11628Q	DO229029	LICA	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1667
p.T6478N	DO229029	LICA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0833
p.P3117T	DO229029	LICA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.7031
p.P6325T	DO229028	LICA	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.1111
p.P6325T	DO35561	PBCA	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.1111
p.P5236T	DO229028	LICA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1944
p.T3719N	DO229028	LICA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2778
p.H11370N	DO229028	LICA	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.3056
p.P9452Q	DO229028	LICA	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation altering degron motif	0.7035
p.P3721Q	DO229028	LICA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation altering degron motif	0.7035
p.P3290H	DO229022	LICA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1944
p.D6873E	DO229022	LICA	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0833
p.R5084S	DO229022	LICA	ICGC	PVTSS	DEG_SPOP_SBC_1	5089:5093	Mutation rewiring degron network	0.1944
p.T966N	DO229022	LICA	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation altering degron motif	0.7055
p.T10948N	DO229025	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.3056
p.T11579N	DO229025	LICA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.25
p.L11155M	DO229024	LICA	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1667
p.S11304R	DO229027	LICA	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation altering degron motif	0.7427
p.T3304I	DO229027	LICA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.25
p.A8266D	DO229026	LICA	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1389
p.T11620N	DO229026	LICA	ICGC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation altering degron motif	0.7055
p.P700Q	DO229026	LICA	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation altering degron motif	0.7035
p.L13147I	DO229032	LICA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2778
p.L13147I	DO229032	LICA	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.25
p.L13147I	DO50788	LICA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.2778
p.L13147I	DO50788	LICA	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.25
p.A9480E	DO229032	LICA	ICGC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation rewiring degron network	0.2222
p.P439Q	DO229031	LICA	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1111
p.S13606R	DO229031	LICA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation altering degron motif	0.7427
p.N10173K	DO229031	LICA	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.1111
p.T5825K	DO229031	LICA	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2778
p.T5825K	DO229034	LICA	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2778
p.D4019E	DO229031	LICA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.3056
p.H9824N	DO229034	LICA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.25
p.D958E	DO229034	LICA	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.2222
p.T11433N	DO229036	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation altering degron motif	0.7055
p.S4598Y	DO229036	LICA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1944
p.S12011Y	DO229036	LICA	ICGC	LFTPLTT	DEG_SCF_FBW7_1	12001:12007	Mutation rewiring degron network	0.2222
p.S3286Y	DO229036	LICA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.0833
p.P8695Q	DO229035	LICA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.2222
p.T10339N	DO229035	LICA	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2222
p.T4032K	DO229035	LICA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1389
p.A2464D	DO229035	LICA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.A8783E	DO229038	LICA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2222
p.A8783E	DO229038	LICA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.25
p.A1508D	DO229037	LICA	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.S5823R	DO229041	LICA	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation altering degron motif	0.7427
p.T3235N	DO229041	LICA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.7055
p.P6503H	DO229045	LICA	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1389
p.T9331K	DO229045	LICA	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.2778
p.P7768T	DO229045	LICA	ICGC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.0833
p.L4017M	DO229045	LICA	ICGC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.25
p.T11179S	DO229047	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.6005
p.T1834I	DO229048	LICA	ICGC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.2778
p.T1834I	DO229048	LICA	ICGC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.1111
p.S13132T	DO229052	LICA	ICGC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation blocking phosphorylation signal	0.5556
p.D8899E	DO229006	LICA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation rewiring degron network	0.1944
p.T6884K	DO229006	LICA	ICGC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation altering degron motif	0.7306
p.T2511N	DO229006	LICA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation altering degron motif	0.7055
p.P11177T	DO229009	LICA	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.7031
p.P2471T	DO229009	LICA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.1111
p.T13918N	DO229009	LICA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.3056
p.T13160K	DO229009	LICA	ICGC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.3056
p.L5658I	DO229008	LICA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0556
p.H1649N	DO229008	LICA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0833
p.T6301R	DO50885	LICA	ICGC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.A1856T	DO228907	LICA	ICGC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.3056
p.T7105K	DO228907	LICA	ICGC	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation altering degron motif	0.7306
p.A3569V	DO50970	LICA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.5825
p.T8276I	DO50970	LICA	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7078
p.A1005G	DO50944	LICA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.6429
p.P11058T	DO50924	LICA	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1111
p.S9276I	DO44868	LICA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.25
p.S9276I	DO44868	LICA	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.1389
p.T4600S	DO44856	LICA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.25
p.T6590P	DO44854	LICA	ICGC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation blocking phosphorylation signal	0.5833
p.V4790G	DO44806	LICA	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1111
p.M11687V	DO22810	LICA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1111
p.S4782L	DO231593	LINC	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.7667
p.S4782L	ACH-001554	Eye Cancer	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.7667
p.V1103A	DO231527	LINC	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1111
p.S10460I	DO23246	LINC	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation blocking phosphorylation signal	0.6667
p.V5617A	DO23218	LINC	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.25
p.P1737H	DO23210	LINC	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.F12531L	DO23224	LINC	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.0556
p.P8278S	DO23204	LINC	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.3056
p.A11898S	DO23272	LINC	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.0556
p.Q3111R	DO231613	LINC	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.G11258C	DO231655	LINC	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1944
p.G11258V	DO231655	LINC	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1944
p.D9262G	DO23188	LINC	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.2222
p.D9262G	DO23188	LINC	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.25
p.N13594D	DO23370	LINC	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.1111
p.I9167T	DO45079	LINC	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.1944
p.S9729C	DO50814	LIRI	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1944
p.T11886S	DO50793	LIRI	ICGC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation altering degron motif	0.7116
p.T7718A	DO50772	LIRI	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1389
p.N12189S	DO45287	LIRI	ICGC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.0833
p.R7969G	DO45299	LIRI	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.0833
p.T7340A	DO45155	LIRI	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation blocking phosphorylation signal	0.6944
p.G8208A	DO45151	LIRI	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.6429
p.L12835F	DO45131	LIRI	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1111
p.L12835F	DO45131	LIRI	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.25
p.T357R	DO45127	LIRI	ICGC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation rewiring degron network	0.3056
p.H8068L	DO45111	LIRI	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation rewiring degron network	0.25
p.A8693S	DO48689	LIRI	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.2778
p.E5626D	DO23529	LIRI	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.6758
p.T12993I	DO229177	LMS	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.1667
p.T12993I	DO229177	LMS	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.0556
p.T12993I	DO229177	LMS	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.1944
p.S12373F	DO229177	LMS	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0556
p.R10696K	DO229177	LMS	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.2222
p.P5657S	DO230556	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0833
p.K5232N	DO230950	LUSC	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.K5232N	DO224638	LUSC	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.K5232N	DO34809	PACA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.D5831V	DO230976	LUSC	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1111
p.D5831V	DO224626	LUSC	ICGC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1111
p.S10457L	DO230982	LUSC	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.S10457L	DO222595	MELA	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.S10457L	DO229465	SKCA	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.3056
p.F13926L	DO231016	LUSC	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.0833
p.V11042L	DO231049	LUSC	ICGC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2222
p.T10338A	DO231040	LUSC	ICGC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation blocking phosphorylation signal	0.6944
p.D3529Y	DO231047	LUSC	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1944
p.P4854Q	DO231179	LUSC	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.1111
p.M6477I	DO231136	LUSC	ICGC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.0556
p.P5347A	DO231204	LUSC	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.2778
p.S971I	DO27833	MALY	ICGC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1944
p.L9532P	DO27781	MALY	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.1944
p.F301L	DO228343	MALY	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.1667
p.D12834G	DO228371	MALY	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1389
p.D12834G	DO228371	MALY	ICGC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2778
p.D12834G	SIDM01008	B-Cell Non-Hodgkin's Lymphoma	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1389
p.D12834G	SIDM01008	B-Cell Non-Hodgkin's Lymphoma	GDSC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2778
p.D12834G	ACH-000315	Lymphoma	CCLE	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1389
p.D12834G	ACH-000315	Lymphoma	CCLE	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2778
p.D12834G	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1389
p.D12834G	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.2778
p.I468T	DO52679	MALY	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.0833
p.S7286T	DO52674	MALY	ICGC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation altering degron motif	0.6005
p.F10843S	DO52655	MALY	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.S11091L	DO220851	MELA	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation altering degron motif	0.8778
p.S11091L	DO47331	SKCM	ICGC	VPTPTVS	DEG_SCF_FBW7_1	11085:11091	Mutation altering degron motif	0.8778
p.S10034F	DO220851	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.2778
p.F10531S	DO220857	MELA	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.2222
p.G1727E	DO220857	MELA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	DO222908	MELA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM01104	Melanoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM00965	Small Cell Lung Carcinoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM00203	Ewing's Sarcoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM01220	Glioma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM00379	Glioma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM00431	T-Lymphoblastic Leukemia	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.G1727E	SIDM01777	Pancreatic Carcinoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.25
p.S10099F	DO220856	MELA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1111
p.M8699I	DO220859	MELA	ICGC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1111
p.S2327F	DO220853	MELA	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.7982
p.S2327F	DO220911	MELA	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.7982
p.S2327F	DO222875	MELA	ICGC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation altering degron motif	0.7982
p.S9329N	DO220852	MELA	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.7069
p.V10933G	DO220855	MELA	ICGC	IPTPTVS	DEG_SCF_FBW7_1	10921:10927	Mutation rewiring degron network	0.1667
p.V10933G	DO220855	MELA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation rewiring degron network	0.0556
p.S8908L	DO220854	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation altering degron motif	0.7667
p.S8908L	DO220899	MELA	ICGC	PVTTS	DEG_SPOP_SBC_1	8904:8908	Mutation altering degron motif	0.7667
p.S202F	DO220872	MELA	ICGC	SKENA	DEG_APCC_KENBOX_2	202:206	Mutation altering degron motif	0.7982
p.D713N	DO220879	MELA	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.0556
p.M8785I	DO220878	MELA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1667
p.M8785I	DO220878	MELA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.1944
p.S10885F	DO220875	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885F	DO222557	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885F	DO222880	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885F	SIDM01694	B-Lymphoblastic Leukemia	GDSC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885F	ACH-000728	Leukemia	CCLE	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885L	DO220875	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S7112F	DO220875	MELA	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7982
p.P8675L	DO220877	MELA	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.2778
p.V11408I	DO220877	MELA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1944
p.P3465S	DO220877	MELA	ICGC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation rewiring degron network	0.1944
p.P10880S	DO220877	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.6752
p.P3237L	DO220877	MELA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.S9822F	DO220877	MELA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.3056
p.E3896K	DO220877	MELA	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.3056
p.E3896K	DO220906	MELA	ICGC	VTSSS	DEG_SPOP_SBC_1	3897:3901	Mutation rewiring degron network	0.3056
p.P11525L	DO220876	MELA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1389
p.R9818K	DO220882	MELA	ICGC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation altering degron motif	0.6126
p.T513I	DO220881	MELA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.3056
p.T12827I	DO220884	MELA	ICGC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.7078
p.R9277K	DO220889	MELA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.2222
p.R9277K	DO220889	MELA	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.1111
p.P11299L	DO220886	MELA	ICGC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.2778
p.P11299L	DO220886	MELA	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.P11299L	SIDM00336	Melanoma	GDSC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.2778
p.P11299L	SIDM00336	Melanoma	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.P11299L	ACH-000881	Skin Cancer	CCLE	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.2778
p.P11299L	ACH-000881	Skin Cancer	CCLE	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.P11299L	MEL-JUSO	skin	COSMIC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.2778
p.P11299L	MEL-JUSO	skin	COSMIC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.T8974I	DO220886	MELA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.3056
p.S7993I	DO220886	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.2222
p.P4860S	DO220885	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2778
p.S8081F	DO220885	MELA	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.1389
p.P11581S	DO220893	MELA	ICGC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.3056
p.P3580L	DO220895	MELA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.0833
p.L3736F	DO220895	MELA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0833
p.P11114L	DO220895	MELA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.A9489T	DO220891	MELA	ICGC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation rewiring degron network	0.3056
p.E6049K	DO220891	MELA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2222
p.S7120F	DO220891	MELA	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.1667
p.S7120F	DO219878	SKCA	ICGC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation rewiring degron network	0.1667
p.L1445F	DO220890	MELA	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation altering degron motif	0.6981
p.T11169I	DO220899	MELA	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.2222
p.T11169I	DO220899	MELA	ICGC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1111
p.S8066F	DO220899	MELA	ICGC	VGTSS	DEG_SPOP_SBC_1	8061:8065	Mutation blocking phosphorylation signal	0.75
p.S10814F	DO220899	MELA	ICGC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.1111
p.S5352F	DO220898	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7982
p.V10874I	DO220898	MELA	ICGC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.V10874I	DO220898	MELA	ICGC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation rewiring degron network	0.25
p.V10874I	DO220898	MELA	ICGC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.25
p.S2081L	DO220903	MELA	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.P3117S	DO220903	MELA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.6752
p.P3117S	DO222775	MELA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.6752
p.R9725K	DO220903	MELA	ICGC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.0833
p.P11420S	DO220902	MELA	ICGC	PETTT	DEG_SPOP_SBC_1	11429:11433	Mutation rewiring degron network	0.0833
p.S4770F	DO220902	MELA	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1111
p.P9336S	DO220902	MELA	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.1389
p.P9548L	DO220905	MELA	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.3056
p.R9277M	DO220907	MELA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation rewiring degron network	0.2222
p.R9277M	DO220907	MELA	ICGC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.1111
p.P5642S	DO220906	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.2778
p.SP5641SS	DO220906	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0
p.S4939F	DO220911	MELA	ICGC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.25
p.P7492S	DO220913	MELA	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1667
p.P7492S	DO229456	SKCA	ICGC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1667
p.L5803F	DO222494	MELA	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.25
p.F10701Y	DO222494	MELA	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.0833
p.S9534F	DO222409	MELA	ICGC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.1389
p.E11372K	DO222418	MELA	ICGC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation rewiring degron network	0.25
p.S9441L	DO222415	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	9437:9441	Mutation altering degron motif	0.7667
p.Q3306K	DO222458	MELA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.1944
p.V10835A	DO222516	MELA	ICGC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.3056
p.E8094K	DO222527	MELA	ICGC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.2778
p.E8094K	DO222527	MELA	ICGC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2222
p.S10189F	DO222527	MELA	ICGC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation rewiring degron network	0.25
p.P2724S	DO222546	MELA	ICGC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.6752
p.S7973C	DO222632	MELA	ICGC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.1944
p.P10098S	DO222632	MELA	ICGC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.0833
p.R8310K	DO222632	MELA	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.R8310K	SIDM01175	Other Sarcomas	GDSC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.R8310K	ACH-002309	Sarcoma	CCLE	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.R8310K	SW684	soft tissue	COSMIC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation rewiring degron network	0.1389
p.S308F	DO222638	MELA	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	SIDM00545	Melanoma	GDSC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	SIDM00568	Gastric Carcinoma	GDSC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	ACH-000247	Gastric Cancer	CCLE	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	ACH-000987	Skin Cancer	CCLE	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	OCUM-1	stomach	COSMIC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S308F	Mewo	skin	COSMIC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.7982
p.S9553F	DO222644	MELA	ICGC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation altering degron motif	0.9093
p.P8206S	DO222647	MELA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.3056
p.S4873F	DO222653	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.1389
p.S4873F	DO229446	SKCA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.1389
p.E8768K	DO222653	MELA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.1944
p.E8768K	DO222653	MELA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.1111
p.S912F	DO222653	MELA	ICGC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0556
p.S6060F	DO222653	MELA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.25
p.G3546R	DO222749	MELA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1389
p.P7716S	DO222749	MELA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.D11390N	DO222702	MELA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.1944
p.V4773G	DO222702	MELA	ICGC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1944
p.P9270S	DO222702	MELA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation altering degron motif	0.6752
p.S5354L	DO222702	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.3056
p.K7785N	DO222702	MELA	ICGC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation substituting flanking lysine	0.3333
p.G10546K	DO222731	MELA	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.1389
p.G10546K	DO222731	MELA	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.3056
p.G8781E	DO222731	MELA	ICGC	ISTPLTT	DEG_SCF_FBW7_1	8773:8779	Mutation rewiring degron network	0.2778
p.G8781E	DO222731	MELA	ICGC	PLTTT	DEG_SPOP_SBC_1	8776:8780	Mutation rewiring degron network	0.3056
p.P1196L	DO222868	MELA	ICGC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation altering degron motif	0.7582
p.G36E	DO222868	MELA	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.1944
p.G10546R	DO222868	MELA	ICGC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.1389
p.G10546R	DO222868	MELA	ICGC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.3056
p.S8321F	DO222875	MELA	ICGC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation altering degron motif	0.7982
p.P6325L	DO222880	MELA	ICGC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.1111
p.P4852S	DO222880	MELA	ICGC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.0556
p.S9273F	DO222880	MELA	ICGC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation altering degron motif	0.7982
p.S9332F	DO222887	MELA	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.25
p.P5347S	DO222887	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.2778
p.S7988P	DO222810	MELA	ICGC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation altering degron motif	0.6752
p.L7096V	DO222810	MELA	ICGC	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.1389
p.ME3238IK	DO222824	MELA	ICGC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0
p.H13754Y	DO222837	MELA	ICGC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.2222
p.G1097E	DO222843	MELA	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.2778
p.G697R	DO222843	MELA	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation altering degron motif	0.6457
p.E5626K	DO222843	MELA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7022
p.E5626K	DO229456	SKCA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.7022
p.P2886L	DO222908	MELA	ICGC	TFEFSEVPSL	DEG_COP1_1	2891:2900	Mutation rewiring degron network	0.1944
p.E1016K	DO232858	NACA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1111
p.E1016K	DO218861	SKCA	ICGC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.1111
p.G5226E	DO233295	NACA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.3056
p.S2409P	DO229183	NKTL	ICGC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.1667
p.P3121S	DO50684	ORCA	ICGC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.3056
p.T8221R	DO50687	ORCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1389
p.A5343S	DO50713	ORCA	ICGC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.S5334F	DO27943	ORCA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.2222
p.P11316L	DO27943	ORCA	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1667
p.S3576C	DO217836	ORCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.1944
p.S8267F	DO232051	ORCA	ICGC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1667
p.Y1739H	DO232007	ORCA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.1944
p.A6051T	DO46591	OV	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2778
p.P10448L	DO49135	PACA	ICGC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.R12038C	DO33176	PACA	ICGC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1944
p.R12038C	DO33176	PACA	ICGC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0556
p.T3574K	DO46733	PACA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.D3737H	DO34640	PACA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.0556
p.I8166V	DO32980	PACA	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.2222
p.I8166V	DO32980	PACA	ICGC	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.0556
p.M5316I	DO32904	PACA	ICGC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation rewiring degron network	0.1111
p.P10687L	DO32849	PACA	ICGC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.3056
p.R10400K	DO32831	PACA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.0833
p.G7334E	DO35198	PACA	ICGC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.6087
p.S10946R	DO51493	PACA	ICGC	AVTST	DEG_SPOP_SBC_1	10943:10947	Mutation altering degron motif	0.7427
p.P3536L	DO51482	PACA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.7582
p.G8148D	DO51470	PACA	ICGC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.0556
p.A11808S	DO227648	PACA	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation altering degron motif	0.7588
p.R469I	DO35460	PACA	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.0556
p.D11685H	DO35442	PACA	ICGC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.0556
p.S11820P	DO35442	PACA	ICGC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1111
p.V13921F	DO221544	PACA	ICGC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2222
p.P11316A	DO50305	PAEN	ICGC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1667
p.A2100D	DO52124	PAEN	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.3056
p.P3536Q	DO228141	PBCA	ICGC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation altering degron motif	0.7035
p.A7778T	DO228772	PBCA	ICGC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation altering degron motif	0.6028
p.E4605V	DO35558	PBCA	ICGC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.7693
p.S1738I	DO232761	PBCA	ICGC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.2222
p.P7716H	DO232761	PBCA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.0833
p.A516T	DO232761	PBCA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.2222
p.T11744P	DO232761	PBCA	ICGC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.0556
p.T11744P	DO232761	PBCA	ICGC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.1111
p.A6051V	DO232761	PBCA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2778
p.I5233M	DO232224	PBCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.2778
p.A1487D	DO232224	PBCA	ICGC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2222
p.G7733D	DO232224	PBCA	ICGC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.2222
p.G7733D	DO232224	PBCA	ICGC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.1944
p.A11161E	DO232913	PEME	ICGC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation altering degron motif	0.7701
p.S8674Y	DO233019	PEME	ICGC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.25
p.P41L	DO230583	PRAD	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation altering degron motif	0.7582
p.T12355I	DO46791	PRAD	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation altering degron motif	0.7078
p.L464F	DO51131	PRAD	ICGC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.1944
p.S9453Y	DO228398	PRAD	ICGC	LYSTPSGS	DEG_SCF_FBW7_1	9448:9455	Mutation altering degron motif	0.6009
p.S1094N	DO36556	READ	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation altering degron motif	0.7069
p.R10996K	DO47096	RECA	ICGC	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.3056
p.T11942S	DO46893	RECA	ICGC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation rewiring degron network	0.1111
p.S10412I	DO46844	RECA	ICGC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation altering degron motif	0.7341
p.R9330K	DO219878	SKCA	ICGC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.V2459D	DO228011	SKCA	ICGC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.7785
p.A11240T	DO229494	SKCA	ICGC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.2222
p.R507K	DO229446	SKCA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.3056
p.T509A	DO229446	SKCA	ICGC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.6028
p.G6045E	DO229446	SKCA	ICGC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1111
p.S8973F	DO229459	SKCA	ICGC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.7982
p.G3302E	DO229453	SKCA	ICGC	NLYSGTP	CBL_PTK	3295:3301	Mutation rewiring degron network	0.3056
p.G11526E	DO229456	SKCA	ICGC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.1667
p.E5805G	DO229456	SKCA	ICGC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.3056
p.S8220L	DO229456	SKCA	ICGC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.1667
p.D31N	DO229462	SKCA	ICGC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.0556
p.P2910L	DO229462	SKCA	ICGC	LPTPGQS	DEG_SCF_FBW7_1	2907:2913	Mutation altering degron motif	0.7582
p.M3564I	DO229462	SKCA	ICGC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6507
p.P541S	DO229462	SKCA	ICGC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.1111
p.P11392L	DO229462	SKCA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.25
p.P11114S	DO229467	SKCA	ICGC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation rewiring degron network	0.25
p.R1098K	DO229470	SKCA	ICGC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.25
p.D12523N	DO229479	SKCA	ICGC	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation rewiring degron network	0.1111
p.D12523N	DO229479	SKCA	ICGC	PGTST	DEG_SPOP_SBC_1	12517:12521	Mutation rewiring degron network	0.2778
p.T3717K	DO229479	SKCA	ICGC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2222
p.S1656P	DO229479	SKCA	ICGC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.2778
p.G1440E	DO218863	SKCA	ICGC	LAPSEQTTITLPM	DEG_ODPH_VHL_1	1445:1457	Mutation rewiring degron network	0.1944
p.F2090Y	DO229502	SKCA	ICGC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.25
p.F2090Y	DO229502	SKCA	ICGC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1944
p.S305N	DO229502	SKCA	ICGC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation rewiring degron network	0.2778
p.S9170F	DO218884	SKCA	ICGC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.1111
p.D12990N	DO218884	SKCA	ICGC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation rewiring degron network	0.25
p.D12990N	DO218884	SKCA	ICGC	APTST	DEG_SPOP_SBC_1	12979:12983	Mutation rewiring degron network	0.1389
p.D12990N	DO218884	SKCA	ICGC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation rewiring degron network	0.2778
p.P899S	DO37432	SKCM	ICGC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.P899S	SIDM00336	Melanoma	GDSC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.P899S	ACH-000881	Skin Cancer	CCLE	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.P899S	MEL-JUSO	skin	COSMIC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.25
p.G693R	DO37946	SKCM	ICGC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.25
p.Q12350K	DO229216	THCA	ICGC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.25
p.Q12350K	DO229216	THCA	ICGC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.0833
p.S2498C	DO231467	THCA	ICGC	VGSTT	DEG_SPOP_SBC_1	2508:2512	Mutation rewiring degron network	0.0556
p.P11392T	DO231295	THCA	ICGC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation rewiring degron network	0.25
p.S5231G	DO233978	THCA	ICGC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation altering degron motif	0.6993
p.P13608R	DO230451	UTCA	ICGC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.S8265P	SIDM02076	Esophageal Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1111
p.V1082I	SIDM02050	Colorectal Carcinoma	GDSC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.0833
p.L1499P	SIDM02070	Esophageal Carcinoma	GDSC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.3056
p.D1843G	SIDM02059	Colorectal Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.1111
p.V217G	SIDM02071	Esophageal Carcinoma	GDSC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation rewiring degron network	0.2778
p.S5351A	SIDM01954	Colorectal Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.7588
p.E11245D	SIDM01266	Colorectal Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.5647
p.G501R	SIDM01104	Melanoma	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G501R	SIDM01015	Chronic Myelogenous Leukemia	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G501R	SIDM00082	Melanoma	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G501R	JURL-MK1	haematopoietic and lymphoid tissue	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G501R	SK-MEL-31	skin	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G501R	SK-MEL-2	skin	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.G1764A	SIDM00084	Glioblastoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	SIDM00084	Glioblastoma	GDSC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	SIDM00148	Breast Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	SIDM00148	Breast Carcinoma	GDSC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	ACH-000019	Breast Cancer	CCLE	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	ACH-000019	Breast Cancer	CCLE	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	ACH-000028	Breast Cancer	CCLE	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	ACH-000028	Breast Cancer	CCLE	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	ACH-000376	Brain Cancer	CCLE	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	ACH-000376	Brain Cancer	CCLE	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	MCF7	breast	COSMIC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	MCF7	breast	COSMIC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.G1764A	SF295	central nervous system	COSMIC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation rewiring degron network	0.25
p.G1764A	SF295	central nervous system	COSMIC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation rewiring degron network	0.0556
p.S13911C	SIDM00541	Colorectal Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911C	ACH-000926	Colon/Colorectal Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911C	HT55	large intestine	COSMIC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.A12822V	SIDM00993	Plasma Cell Myeloma	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.3056
p.A12822V	SIDM00993	Plasma Cell Myeloma	GDSC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1667
p.A12822V	AMO-1	haematopoietic and lymphoid tissue	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.3056
p.A12822V	AMO-1	haematopoietic and lymphoid tissue	COSMIC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.1667
p.T6063S	SIDM00499	Prostate Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1667
p.T6063S	ACH-000956	Prostate Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1667
p.T6063S	22RV1	prostate	COSMIC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1667
p.T10854A	SIDM00958	Chronic Myelogenous Leukemia	GDSC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	SIDM00958	Chronic Myelogenous Leukemia	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	SIDM00576	Acute Myeloid Leukemia	GDSC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	SIDM00576	Acute Myeloid Leukemia	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	SIDM00243	Other Solid Cancers	GDSC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	SIDM00243	Other Solid Cancers	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	ACH-000920	Leukemia	CCLE	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	ACH-000920	Leukemia	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	ACH-001197	Lymphoma	CCLE	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	ACH-001197	Lymphoma	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	ACH-002288	Embryonal Cancer	CCLE	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	ACH-002288	Embryonal Cancer	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	ACH-002290	Leukemia	CCLE	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	ACH-002290	Leukemia	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	CML-T1	haematopoietic and lymphoid tissue	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	NKM-1	haematopoietic and lymphoid tissue	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	NKM-1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.T10854A	NEC8	testis	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation rewiring degron network	0.1667
p.T10854A	NEC8	testis	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation rewiring degron network	0.1944
p.F4012L	SIDM01043	Other Sarcomas	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1111
p.F4012L	ACH-000913	Endometrial/Uterine Cancer	CCLE	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1111
p.F4012L	ESS-1	endometrium	COSMIC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1111
p.T438S	SIDM00422	Hodgkin's Lymphoma	GDSC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.0833
p.T438S	ACH-001203	Lymphoma	CCLE	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.0833
p.T438S	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.0833
p.A10859E	SIDM00958	Chronic Myelogenous Leukemia	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	SIDM00576	Acute Myeloid Leukemia	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	SIDM00243	Other Solid Cancers	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	ACH-001197	Lymphoma	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	NEC8	testis	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	CML-T1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.A10859E	NKM-1	haematopoietic and lymphoid tissue	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7701
p.P11168L	SIDM00521	Small Cell Lung Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.25
p.P11168L	SIDM00521	Small Cell Lung Carcinoma	GDSC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.0833
p.P11168L	ACH-000743	Lung Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.25
p.P11168L	ACH-000743	Lung Cancer	CCLE	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.0833
p.P11168L	COR-L95	lung	COSMIC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.25
p.P11168L	COR-L95	lung	COSMIC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.0833
p.S5174F	SIDM00973	Melanoma	GDSC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1667
p.S5174F	ACH-000827	Skin Cancer	CCLE	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1667
p.S5174F	WM793B	skin	COSMIC	APSTS	DEG_SPOP_SBC_1	5164:5168	Mutation rewiring degron network	0.1667
p.P4458T	SIDM00770	Small Cell Lung Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458T	ACH-000559	Lung Cancer	CCLE	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.P4458T	NCI-H1836	lung	COSMIC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1111
p.S7719P	SIDM00194	Colorectal Carcinoma	GDSC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1667
p.S7719P	ACH-000532	Colon/Colorectal Cancer	CCLE	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1667
p.S7719P	SNU-61	large intestine	COSMIC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.1667
p.T11986I	SIDM00455	Pancreatic Carcinoma	GDSC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.2778
p.T11986I	ACH-000599	Pancreatic Cancer	CCLE	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.2778
p.T11986I	PA-TU-8902	pancreas	COSMIC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.2778
p.T7114A	SIDM01156	Small Cell Lung Carcinoma	GDSC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7139
p.T7114A	ACH-000890	Lung Cancer	CCLE	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7139
p.T7114A	SW1271	lung	COSMIC	PISST	DEG_SPOP_SBC_1	7110:7114	Mutation altering degron motif	0.7139
p.S8688P	SIDM01043	Other Sarcomas	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.5641
p.S8688P	ACH-000913	Endometrial/Uterine Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.5641
p.S8688P	ESS-1	endometrium	COSMIC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.5641
p.V12813A	SIDM00215	Colorectal Carcinoma	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0556
p.V12813A	ACH-000708	Colon/Colorectal Cancer	CCLE	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0556
p.V12813A	SNU-283	large intestine	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.0556
p.P11540L	SIDM00353	Other Sarcomas	GDSC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	SIDM01217	Other Blood Cancers	GDSC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	SIDM00603	Head and Neck Carcinoma	GDSC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	ACH-000505	Sarcoma	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	ACH-001543	Head and Neck Cancer	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	ACH-002276	Leukemia	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	MY-M12	haematopoietic and lymphoid tissue	COSMIC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	RKN	ovary	COSMIC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.P11540L	KOSC-2	upper aerodigestive tract	COSMIC	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.2222
p.G5756E	SIDM00499	Prostate Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.2222
p.G5756E	ACH-000956	Prostate Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.2222
p.G5756E	22RV1	prostate	COSMIC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.2222
p.M8698V	SIDM01139	Pancreatic Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1389
p.M8698V	ACH-000042	Pancreatic Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1389
p.M8698V	PANC-02-03	pancreas	COSMIC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1389
p.K3718T	SIDM01123	Prostate Carcinoma	GDSC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation substituting flanking lysine	0.3611
p.K3718T	ACH-000177	Prostate Cancer	CCLE	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation substituting flanking lysine	0.3611
p.K3718T	NCI-H660	prostate	COSMIC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation substituting flanking lysine	0.3611
p.A11688S	SIDM00570	Gastric Carcinoma	GDSC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1389
p.A11688S	ACH-000674	Gastric Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1389
p.A11688S	NUGC-4	stomach	COSMIC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.1389
p.P8206H	SIDM00216	Colorectal Carcinoma	GDSC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.3056
p.P8206H	ACH-000989	Colon/Colorectal Cancer	CCLE	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.3056
p.P8206H	SNU-175	large intestine	COSMIC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation rewiring degron network	0.3056
p.N11367S	SIDM00303	Ovarian Carcinoma	GDSC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.5958
p.N11367S	ACH-000584	Ovarian Cancer	CCLE	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.5958
p.N11367S	JHOS-4	ovary	COSMIC	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.5958
p.S11050G	SIDM01119	Other Solid Cancers	GDSC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.6993
p.S11050G	ACH-000775	Lung Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.6993
p.S11050G	NCI-H727	lung	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.6993
p.P5654L	SIDM01119	Other Solid Cancers	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.P5654L	ACH-000775	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.P5654L	NCI-H727	lung	COSMIC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1667
p.L12680F	SIDM00545	Melanoma	GDSC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0833
p.L12680F	ACH-000987	Skin Cancer	CCLE	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0833
p.L12680F	Mewo	skin	COSMIC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0833
p.P12673S	SIDM00545	Melanoma	GDSC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.P12673S	ACH-000987	Skin Cancer	CCLE	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.P12673S	Mewo	skin	COSMIC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.S11596F	SIDM00545	Melanoma	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.0556
p.S11596F	ACH-000987	Skin Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.0556
p.S11596F	Mewo	skin	COSMIC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.0556
p.S8154F	SIDM00545	Melanoma	GDSC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.2222
p.S8154F	ACH-000987	Skin Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.2222
p.S8154F	Mewo	skin	COSMIC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.2222
p.P563L	SIDM00545	Melanoma	GDSC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.P563L	ACH-000987	Skin Cancer	CCLE	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.P563L	Mewo	skin	COSMIC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0556
p.T7477M	SIDM00773	Non-Cancerous	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM00967	Ovarian Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM01133	Other Solid Cancers	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM00774	Breast Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM00720	Mesothelioma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T7477M	SIDM01409	Bladder Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.1944
p.T5613S	SIDM00625	Other Sarcomas	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.T5613S	ACH-000449	Sarcoma	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.T5613S	MES-SA	soft tissue	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.G9315V	SIDM00857	Melanoma	GDSC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.0556
p.G9315V	ACH-000572	Skin Cancer	CCLE	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.0556
p.G9315V	G-361	skin	COSMIC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.0556
p.A6888V	SIDM00962	Chronic Myelogenous Leukemia	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2778
p.A6888V	BV-173	haematopoietic and lymphoid tissue	COSMIC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.2778
p.E160K	SIDM01722	Non-Cancerous	GDSC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1944
p.E160K	SIDM00174	Head and Neck Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1944
p.E160K	SIDM00151	Ovarian Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1944
p.E160K	SIDM00815	Ovarian Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1944
p.Q1086K	SIDM00935	Other Solid Cancers	GDSC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1944
p.Q1086K	ACH-002091	Skin Cancer	CCLE	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1944
p.Q1086K	CAL-39	vulva	COSMIC	AGSST	DEG_SPOP_SBC_1	1091:1095	Mutation rewiring degron network	0.1944
p.S10863T	SIDM00572	Gastric Carcinoma	GDSC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7116
p.S10863T	SIDM00572	Gastric Carcinoma	GDSC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7116
p.S10863T	ACH-000911	Gastric Cancer	CCLE	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7116
p.S10863T	ACH-000911	Gastric Cancer	CCLE	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7116
p.S10863T	NUGC-3	stomach	COSMIC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.7116
p.S10863T	NUGC-3	stomach	COSMIC	AESSS	DEG_SPOP_SBC_1	10859:10863	Mutation altering degron motif	0.7116
p.T8214I	SIDM00572	Gastric Carcinoma	GDSC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.7078
p.T8214I	NUGC-3	stomach	COSMIC	PGSTPEST	DEG_SCF_FBW7_1	8207:8214	Mutation altering degron motif	0.7078
p.D6754G	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.D6754G	ACH-002272	Lymphoma	CCLE	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.D6754G	MHH-PREB-1	haematopoietic and lymphoid tissue	COSMIC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.V10104M	SIDM00186	Kidney Carcinoma	GDSC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.25
p.V10104M	ACH-002151	Kidney Cancer	CCLE	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.25
p.V10104M	LB2241-RCC	kidney	COSMIC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.25
p.D6050E	SIDM00128	Head and Neck Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.25
p.D6050E	ACH-002249	Head and Neck Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.25
p.D6050E	JHU-011	upper aerodigestive tract	COSMIC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.25
p.P10699S	SIDM00119	Non-Small Cell Lung Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.P10699S	SIDM00516	Melanoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.P10699S	SIDM00133	Non-Small Cell Lung Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.P12203H	SIDM01090	Colorectal Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7694
p.P12203H	ACH-000943	Colon/Colorectal Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7694
p.P12203H	RKO	large intestine	COSMIC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7694
p.Y6496C	SIDM01090	Colorectal Carcinoma	GDSC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.7087
p.Y6496C	ACH-000943	Colon/Colorectal Cancer	CCLE	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.7087
p.Y6496C	RKO	large intestine	COSMIC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation altering degron motif	0.7087
p.P8960A	SIDM01109	Other Sarcomas	GDSC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.0833
p.P8960A	SK-LMS-1	soft tissue	COSMIC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.0833
p.R12038L	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1944
p.R12038L	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0556
p.R12038L	SIDM00454	Rhabdomyosarcoma	GDSC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1944
p.R12038L	SIDM00454	Rhabdomyosarcoma	GDSC	PVTST	DEG_SPOP_SBC_1	12048:12052	Mutation rewiring degron network	0.0556
p.T11888R	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation altering degron motif	0.8987
p.T11888R	SIDM00454	Rhabdomyosarcoma	GDSC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation altering degron motif	0.8987
p.V11612L	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1667
p.V11612L	ACH-000789	Lung Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1667
p.V11612L	NCI-H810	lung	COSMIC	VPTTT	DEG_SPOP_SBC_1	11618:11622	Mutation rewiring degron network	0.1667
p.T11180A	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.7139
p.T11180A	SIDM00454	Rhabdomyosarcoma	GDSC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation altering degron motif	0.7139
p.H1849R	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00454	Rhabdomyosarcoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00654	Small Cell Lung Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00210	Ovarian Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM01112	Osteosarcoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00650	Small Cell Lung Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00854	Burkitt's Lymphoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00849	Kidney Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00863	Burkitt's Lymphoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM01681	Non-Cancerous	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00673	Breast Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00808	Burkitt's Lymphoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM00760	Small Cell Lung Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM01318	Hepatocellular Carcinoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.H1849R	SIDM01254	Burkitt's Lymphoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation rewiring degron network	0.2778
p.E1761G	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00454	Rhabdomyosarcoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00654	Small Cell Lung Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00210	Ovarian Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM01112	Osteosarcoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00650	Small Cell Lung Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00854	Burkitt's Lymphoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00849	Kidney Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00863	Burkitt's Lymphoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM01681	Non-Cancerous	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00673	Breast Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00808	Burkitt's Lymphoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM00760	Small Cell Lung Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM01318	Hepatocellular Carcinoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.E1761G	SIDM01254	Burkitt's Lymphoma	GDSC	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation altering degron motif	0.7199
p.R15C	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00454	Rhabdomyosarcoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00654	Small Cell Lung Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00210	Ovarian Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM01112	Osteosarcoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00650	Small Cell Lung Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00854	Burkitt's Lymphoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00849	Kidney Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00863	Burkitt's Lymphoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM01681	Non-Cancerous	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00673	Breast Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00808	Burkitt's Lymphoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM00760	Small Cell Lung Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM01318	Hepatocellular Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.R15C	SIDM01254	Burkitt's Lymphoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation rewiring degron network	0.25
p.V5329G	SIDM00336	Melanoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6421
p.V5329G	ACH-000881	Skin Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6421
p.V5329G	MEL-JUSO	skin	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5324:5330	Mutation altering degron motif	0.6421
p.P6312L	SIDM00086	Kidney Carcinoma	GDSC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2778
p.P6312L	ACH-002195	Kidney Cancer	CCLE	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2778
p.P6312L	RXF393	kidney	COSMIC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2778
p.A1838T	SIDM00915	Small Cell Lung Carcinoma	GDSC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1667
p.A1838T	ACH-002173	Lung Cancer	CCLE	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1667
p.A1838T	NCI-H378	lung	COSMIC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1667
p.A10547V	SIDM00377	Other Sarcomas	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM00411	Pancreatic Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM00247	Gastric Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM00023	Esophageal Squamous Cell Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM00271	Gastric Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM00986	Head and Neck Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.A10547V	SIDM01033	Bladder Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation altering degron motif	0.5825
p.R921T	SIDM00377	Other Sarcomas	GDSC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.3056
p.R921T	SKN	soft tissue	COSMIC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.3056
p.S4477P	SIDM00969	Ovarian Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1389
p.S4477P	SIDM00583	Pancreatic Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1389
p.S4477P	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.1389
p.A10887E	SIDM00698	Small Cell Lung Carcinoma	GDSC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2222
p.A10887E	ACH-000506	Lung Cancer	CCLE	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2222
p.A10887E	NCI-H146	lung	COSMIC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2222
p.R973K	SIDM00525	Osteosarcoma	GDSC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1389
p.R973K	ACH-000359	Bone Cancer	CCLE	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1389
p.R973K	MG-63	bone	COSMIC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.1389
p.P1651H	SIDM01197	Colorectal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1389
p.P1651H	ACH-000722	Colon/Colorectal Cancer	CCLE	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1389
p.P1651H	SNU-C1	large intestine	COSMIC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.1389
p.F10332L	SIDM00513	Non-Small Cell Lung Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.587
p.F10332L	ACH-000161	Lung Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.587
p.F10332L	COR-L105	lung	COSMIC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation altering degron motif	0.587
p.T2461R	SIDM00513	Non-Small Cell Lung Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8987
p.T2461R	ACH-000046	Kidney Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8987
p.T2461R	ACH-000161	Lung Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8987
p.T2461R	COR-L105	lung	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation altering degron motif	0.8987
p.S3993A	SIDM01183	Other Solid Cancers	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993A	ACH-001417	Lung Cancer	CCLE	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S3993A	UMC-11	lung	COSMIC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1111
p.S10042I	SIDM01062	Breast Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.0556
p.S10042I	SIDM00438	B-Lymphoblastic Leukemia	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.0556
p.S10042I	MN-60	haematopoietic and lymphoid tissue	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.0556
p.S10042I	HDQ-P1	breast	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.0556
p.E7752D	SIDM01062	Breast Carcinoma	GDSC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.0556
p.E7752D	ACH-000643	Breast Cancer	CCLE	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.0556
p.E7752D	HDQ-P1	breast	COSMIC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation rewiring degron network	0.0556
p.E10403D	SIDM01117	Small Cell Lung Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1667
p.E10403D	ACH-002176	Lung Cancer	CCLE	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1667
p.E10403D	NCI-H748	lung	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1667
p.S1820T	SIDM01117	Small Cell Lung Carcinoma	GDSC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.6005
p.S1820T	ACH-002176	Lung Cancer	CCLE	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.6005
p.S1820T	NCI-H748	lung	COSMIC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation altering degron motif	0.6005
p.T9003S	SIDM01483	Melanoma	GDSC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation altering degron motif	0.7116
p.G5829E	SIDM01483	Melanoma	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1667
p.G5829E	ACH-000582	Skin Cancer	CCLE	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1667
p.G5829E	COLO-741	large intestine	COSMIC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1667
p.P11694L	SIDM00392	Melanoma	GDSC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.3056
p.P11694L	ACH-000810	Skin Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.3056
p.P11694L	SK-MEL-30	skin	COSMIC	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.3056
p.K10171R	SIDM00705	Non-Cancerous	GDSC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.K10171R	SIDM00706	Small Cell Lung Carcinoma	GDSC	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.K10171R	ACH-000290	Lung Cancer	CCLE	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.K10171R	ACH-002369	Non-Cancerous	CCLE	VTPTNT	DEG_SCF_FBW7_1	10181:10186	Mutation substituting flanking lysine	0.1667
p.H11241Q	SIDM00491	Thyroid Gland Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.25
p.H11241Q	ACH-001443	Thyroid Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.25
p.H11241Q	ASH-3	thyroid	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.25
p.Y10117H	SIDM00501	Oral Cavity Carcinoma	GDSC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1667
p.Y10117H	ACH-001332	Head and Neck Cancer	CCLE	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1667
p.Y10117H	BICR78	upper aerodigestive tract	COSMIC	VGTTS	DEG_SPOP_SBC_1	10107:10111	Mutation rewiring degron network	0.1667
p.A11800T	SIDM01030	Esophageal Squamous Cell Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1111
p.A11800T	ACH-000693	Esophageal Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1111
p.A11800T	KYSE-180	oesophagus	COSMIC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1111
p.S11083T	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6005
p.S11083T	ACH-000438	Lung Cancer	CCLE	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6005
p.S11083T	LU-65	lung	COSMIC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.6005
p.S11082R	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.7427
p.S11082R	ACH-000438	Lung Cancer	CCLE	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.7427
p.S11082R	LU-65	lung	COSMIC	EASSAVPTP	DEG_COP1_1	11080:11088	Mutation altering degron motif	0.7427
p.I7710M	SIDM00212	Glioblastoma	GDSC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.I7710M	ACH-000464	Brain Cancer	CCLE	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.I7710M	CAS-1	central nervous system	COSMIC	PVSTT	DEG_SPOP_SBC_1	7701:7705	Mutation rewiring degron network	0.1944
p.S1864P	SIDM00212	Glioblastoma	GDSC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation blocking phosphorylation signal	0.5278
p.S1864P	CAS-1	central nervous system	COSMIC	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation blocking phosphorylation signal	0.5278
p.P9751T	SIDM00393	Gastric Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.P9751T	ACH-001653	Gastric Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.P9751T	SK-GT-2	stomach	COSMIC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.1667
p.R12367G	SIDM00781	Colorectal Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367G	SIDM00781	Colorectal Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.R12367G	SIDM00780	Colorectal Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367G	SIDM00780	Colorectal Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.R12367G	ACH-000967	Colon/Colorectal Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367G	ACH-000967	Colon/Colorectal Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.R12367G	ACH-001199	Colon/Colorectal Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367G	ACH-001199	Colon/Colorectal Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.R12367G	SNU-C2B	large intestine	COSMIC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.0556
p.R12367G	SNU-C2B	large intestine	COSMIC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2222
p.A11496E	SIDM00781	Colorectal Carcinoma	GDSC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1389
p.A11496E	SIDM00780	Colorectal Carcinoma	GDSC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1389
p.A11496E	ACH-000967	Colon/Colorectal Cancer	CCLE	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1389
p.A11496E	ACH-001199	Colon/Colorectal Cancer	CCLE	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1389
p.A11496E	SNU-C2B	large intestine	COSMIC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1389
p.T10697I	SIDM00127	Oral Cavity Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.T10697I	ACH-002250	Head and Neck Cancer	CCLE	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.T10697I	JHU-022	upper aerodigestive tract	COSMIC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.N12824Y	SIDM00680	Colorectal Carcinoma	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.5948
p.N12824Y	ACH-000957	Colon/Colorectal Cancer	CCLE	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.5948
p.N12824Y	LS-180	large intestine	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.5948
p.S9820F	SIDM00185	Melanoma	GDSC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation altering degron motif	0.9093
p.S9820F	ACH-002152	Skin Cancer	CCLE	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation altering degron motif	0.9093
p.S9820F	LB2518-MEL	skin	COSMIC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation altering degron motif	0.9093
p.G7739E	SIDM00185	Melanoma	GDSC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.6087
p.G7739E	ACH-002152	Skin Cancer	CCLE	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.6087
p.G7739E	LB2518-MEL	skin	COSMIC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.6087
p.P5765L	SIDM00855	Other Sarcomas	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.3056
p.S4027R	SIDM01219	Non-Small Cell Lung Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.S4027R	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.S4027R	SIDM01432	Kidney Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.S4027R	SIDM00500	Colorectal Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.2778
p.S13917R	SIDM01126	Small Cell Lung Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM00846	Cervical Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM00694	Other Solid Cancers	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM00879	Breast Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM00808	Burkitt's Lymphoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.S13917R	SIDM01254	Burkitt's Lymphoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7427
p.T4858A	SIDM01126	Small Cell Lung Carcinoma	GDSC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2222
p.T4858A	ACH-001599	Lung Cancer	CCLE	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2222
p.T4858A	NCI-H64	lung	COSMIC	VTTST	DEG_SPOP_SBC_1	4862:4866	Mutation rewiring degron network	0.2222
p.G4788D	SIDM00120	Prostate Carcinoma	GDSC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.G4788D	ACH-000979	Prostate Cancer	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.G4788D	DU-145	prostate	COSMIC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.S11589F	SIDM01175	Other Sarcomas	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.25
p.S11589F	ACH-002309	Sarcoma	CCLE	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.25
p.S11589F	SW684	soft tissue	COSMIC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.25
p.T5628I	SIDM01175	Other Sarcomas	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628I	ACH-002309	Sarcoma	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.T5628I	SW684	soft tissue	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.2778
p.M7514I	SIDM00291	Melanoma	GDSC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.M7514I	ACH-002040	Skin Cancer	CCLE	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.M7514I	HMV-II	skin	COSMIC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.P5830S	SIDM00656	Burkitt's Lymphoma	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1389
p.P5830S	SIDM00538	Esophageal Carcinoma	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1389
p.P5830S	SIDM00641	Burkitt's Lymphoma	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1389
p.P5830S	SIDM01525	Acute Myeloid Leukemia	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.1389
p.T10804A	SIDM00789	Colorectal Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation altering degron motif	0.825
p.T10804A	ACH-000997	Colon/Colorectal Cancer	CCLE	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation altering degron motif	0.825
p.T10804A	ACH-001061	Colon/Colorectal Cancer	CCLE	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation altering degron motif	0.825
p.T10804A	HCT-15	large intestine	COSMIC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation altering degron motif	0.825
p.N3226S	SIDM00041	Gastric Carcinoma	GDSC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2778
p.E11300G	SIDM01251	T-Cell Non-Hodgkin's Lymphoma	GDSC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.3056
p.E11300G	SIDM01251	T-Cell Non-Hodgkin's Lymphoma	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1667
p.E11300G	SIDM00702	Non-Small Cell Lung Carcinoma	GDSC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.3056
p.E11300G	SIDM00702	Non-Small Cell Lung Carcinoma	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1667
p.E11300G	SIDM00701	Non-Cancerous	GDSC	AESSS	DEG_SPOP_SBC_1	11301:11305	Mutation rewiring degron network	0.3056
p.E11300G	SIDM00701	Non-Cancerous	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1667
p.P2413T	SIDM00087	Plasma Cell Myeloma	GDSC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.P2413T	SIDM00529	Breast Carcinoma	GDSC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.P2413T	SIDM00879	Breast Carcinoma	GDSC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.P2413T	SIDM00882	Breast Carcinoma	GDSC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.P2413T	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	VPTST	DEG_SPOP_SBC_1	2415:2419	Mutation rewiring degron network	0.2778
p.T12205S	SIDM00633	Breast Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.6005
p.T12205S	ACH-000759	Breast Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.6005
p.T12205S	MDA-MB-175-VII	breast	COSMIC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.6005
p.A5754T	SIDM00633	Breast Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM00529	Breast Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM00849	Kidney Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM00721	Small Cell Lung Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.A5754T	SIDM01409	Bladder Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.1667
p.E9516K	SIDM00007	Other Solid Cancers	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.1389
p.E9516K	ACH-001550	Skin Cancer	CCLE	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.1389
p.E9516K	MCC13	skin	COSMIC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.1389
p.E9485K	SIDM00007	Other Solid Cancers	GDSC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation altering degron motif	0.591
p.E9485K	ACH-001550	Skin Cancer	CCLE	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation altering degron motif	0.591
p.E9485K	MCC13	skin	COSMIC	PETTS	DEG_SPOP_SBC_1	9484:9488	Mutation altering degron motif	0.591
p.M8676I	SIDM00007	Other Solid Cancers	GDSC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.M8676I	SIDM00716	Squamous Cell Lung Carcinoma	GDSC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.M8676I	ACH-000481	Lung Cancer	CCLE	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.M8676I	ACH-001550	Skin Cancer	CCLE	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.M8676I	MCC13	skin	COSMIC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.M8676I	NCI-H2170	lung	COSMIC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation rewiring degron network	0.3056
p.P8280S	SIDM00007	Other Solid Cancers	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.25
p.P8280S	ACH-001550	Skin Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.25
p.P8280S	MCC13	skin	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.25
p.S8268F	SIDM00007	Other Solid Cancers	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8268F	ACH-001550	Skin Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.S8268F	MCC13	skin	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1944
p.A11575T	SIDM01007	T-Lymphoblastic Leukemia	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.A11575T	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.1389
p.T1162A	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7139
p.T1162A	ACH-002256	Leukemia	CCLE	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7139
p.T1162A	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7139
p.K7327E	SIDM00950	Pancreatic Carcinoma	GDSC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation substituting flanking lysine	0.2778
p.K7327E	DAN-G	pancreas	COSMIC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation substituting flanking lysine	0.2778
p.S6504Y	SIDM00477	Esophageal Carcinoma	GDSC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1111
p.S6504Y	SIDM00803	Kidney Carcinoma	GDSC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1111
p.S6504Y	SIDM00999	Bladder Carcinoma	GDSC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1111
p.S6504Y	SIDM00677	Colorectal Carcinoma	GDSC	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1111
p.I5219T	SIDM01129	Small Cell Lung Carcinoma	GDSC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1111
p.I5219T	ACH-000816	Lung Cancer	CCLE	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1111
p.I5219T	NCI-H524	lung	COSMIC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1111
p.S5611R	SIDM01071	Small Cell Lung Carcinoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0833
p.S5611R	ACH-000515	Lung Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0833
p.S5611R	HCC-33	lung	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.0833
p.E6062D	SIDM00255	Neuroblastoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1944
p.E6062D	ACH-002282	Neuroblastoma	CCLE	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1944
p.E6062D	NB17	autonomic ganglia	COSMIC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1944
p.P7738H	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.7694
p.P7738H	ACH-000647	Esophageal Cancer	CCLE	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.7694
p.P7738H	TE-1	oesophagus	COSMIC	PGTSS	DEG_SPOP_SBC_1	7738:7742	Mutation altering degron motif	0.7694
p.T8275M	SIDM00654	Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00210	Ovarian Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM01112	Osteosarcoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00650	Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00854	Burkitt's Lymphoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00849	Kidney Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00863	Burkitt's Lymphoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM01681	Non-Cancerous	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00673	Breast Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM00760	Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T8275M	SIDM01318	Hepatocellular Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation altering degron motif	0.7423
p.T10681S	SIDM00741	Small Cell Lung Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.T10681S	ACH-000431	Lung Cancer	CCLE	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.T10681S	NCI-H1694	lung	COSMIC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1389
p.M8093V	SIDM00569	Osteosarcoma	GDSC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8093V	SIDM00569	Osteosarcoma	GDSC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1944
p.M8093V	ACH-002178	Bone Cancer	CCLE	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8093V	ACH-002178	Bone Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1944
p.M8093V	NY	bone	COSMIC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8093V	NY	bone	COSMIC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.1944
p.G4788S	SIDM01078	Small Cell Lung Carcinoma	GDSC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.G4788S	ACH-000790	Lung Cancer	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.G4788S	SHP-77	lung	COSMIC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation rewiring degron network	0.1667
p.I2455V	SIDM01078	Small Cell Lung Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2222
p.I2455V	ACH-000790	Lung Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2222
p.I2455V	SHP-77	lung	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2222
p.E522A	SIDM00795	Melanoma	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522A	ACH-000219	Skin Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522A	ACH-002001	Skin Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522A	ACH-002002	Skin Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522A	ACH-002003	Skin Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.E522A	A375	skin	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.0556
p.S10885Y	SIDM00193	Colorectal Carcinoma	GDSC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885Y	ACH-000991	Colon/Colorectal Cancer	CCLE	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.S10885Y	SNU-81	large intestine	COSMIC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation rewiring degron network	0.2778
p.F6315L	SIDM00193	Colorectal Carcinoma	GDSC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.F6315L	SIDM01503	Small Cell Lung Carcinoma	GDSC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.F6315L	ACH-000844	Lung Cancer	CCLE	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.F6315L	ACH-000991	Colon/Colorectal Cancer	CCLE	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.F6315L	SNU-81	large intestine	COSMIC	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.1944
p.S2074F	SIDM00193	Colorectal Carcinoma	GDSC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.0833
p.S2074F	ACH-000991	Colon/Colorectal Cancer	CCLE	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.0833
p.S2074F	SNU-81	large intestine	COSMIC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.0833
p.S1008Y	SIDM00193	Colorectal Carcinoma	GDSC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.712
p.S1008Y	ACH-000991	Colon/Colorectal Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.712
p.S1008Y	SNU-81	large intestine	COSMIC	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation altering degron motif	0.712
p.A508E	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.7701
p.A508E	ACH-000809	Esophageal Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.7701
p.A508E	KYSE-410	oesophagus	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation altering degron motif	0.7701
p.N13905S	SIDM00834	Colorectal Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1111
p.N13905S	SW1463	large intestine	COSMIC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.1111
p.P11260S	SIDM00660	Colorectal Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260S	ACH-000985	Colon/Colorectal Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260S	LS-411N	large intestine	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.V3224M	SIDM00660	Colorectal Carcinoma	GDSC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2222
p.V3224M	ACH-000985	Colon/Colorectal Cancer	CCLE	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2222
p.V3224M	LS-411N	large intestine	COSMIC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation rewiring degron network	0.2222
p.S3985F	SIDM00746	Non-Small Cell Lung Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.9093
p.S3985F	SIDM00254	Neuroblastoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.9093
p.S3985F	SIDM00032	Bladder Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.9093
p.S3985F	SIDM00720	Mesothelioma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.9093
p.S3985F	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.9093
p.P11260L	SIDM01242	Melanoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	SIDM00151	Ovarian Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	ACH-000966	Ovarian Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	ACH-002084	Skin Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	ACH-002162	Skin Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	IGROV-1	ovary	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.P11260L	MMAC-SF	skin	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1389
p.T6337I	SIDM00057	Neuroblastoma	GDSC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7078
p.T6337I	ACH-000676	Brain Cancer	CCLE	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7078
p.T6337I	ACH-002389	Neuroblastoma	CCLE	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7078
p.T6337I	ACN	autonomic ganglia	COSMIC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.7078
p.G313E	SIDM00057	Neuroblastoma	GDSC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.6087
p.G313E	ACH-000676	Brain Cancer	CCLE	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.6087
p.G313E	ACH-002389	Neuroblastoma	CCLE	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.6087
p.G313E	ACN	autonomic ganglia	COSMIC	TSPLSPGVPEA	DEG_COP1_1	307:317	Mutation altering degron motif	0.6087
p.L10553R	SIDM00190	Melanoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2778
p.L10553R	ACH-002097	Skin Cancer	CCLE	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2778
p.L10553R	CP66-MEL	skin	COSMIC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.2778
p.S10404R	SIDM00328	Esophageal Squamous Cell Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM00002	Neuroblastoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM00324	Neuroblastoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM00368	Small Cell Lung Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM01449	Pancreatic Carcinoma	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SIDM00959	Acute Myeloid Leukemia	GDSC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	CMK	haematopoietic and lymphoid tissue	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	NBsusSR	autonomic ganglia	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	HCC-56	large intestine	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	TGW	autonomic ganglia	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	TE-15	oesophagus	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	TE-6	oesophagus	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.S10404R	SBC-5	lung	COSMIC	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1944
p.V11758I	SIDM00227	Neuroblastoma	GDSC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7076
p.V11758I	ACH-001344	Neuroblastoma	CCLE	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7076
p.V11758I	GI-ME-N	autonomic ganglia	COSMIC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7076
p.T12205A	SIDM00002	Neuroblastoma	GDSC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7139
p.T12205A	ACH-002340	Neuroblastoma	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7139
p.T12205A	NBsusSR	autonomic ganglia	COSMIC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation altering degron motif	0.7139
p.T6329I	SIDM00002	Neuroblastoma	GDSC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2222
p.T6329I	ACH-002340	Neuroblastoma	CCLE	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2222
p.T6329I	NBsusSR	autonomic ganglia	COSMIC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation rewiring degron network	0.2222
p.T932A	SIDM00197	Ewing's Sarcoma	GDSC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation blocking phosphorylation signal	0.6111
p.T932A	EW-18	bone	COSMIC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation blocking phosphorylation signal	0.6111
p.M7514L	SIDM00890	Melanoma	GDSC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.M7514L	ACH-000580	Skin Cancer	CCLE	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.M7514L	C32	skin	COSMIC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.1111
p.R10443K	SIDM00337	Melanoma	GDSC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.0833
p.R10443K	ACH-000450	Skin Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.0833
p.R10443K	MEL-HO	skin	COSMIC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.0833
p.H1497Y	SIDM00284	Melanoma	GDSC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6118
p.H1497Y	ACH-000805	Skin Cancer	CCLE	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6118
p.H1497Y	COLO-679	skin	COSMIC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation altering degron motif	0.6118
p.T3433I	SIDM00716	Squamous Cell Lung Carcinoma	GDSC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1389
p.T3433I	ACH-000481	Lung Cancer	CCLE	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1389
p.T3433I	NCI-H2170	lung	COSMIC	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.1389
p.E9324D	SIDM00155	Head and Neck Carcinoma	GDSC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.E9324D	ACH-002296	Head and Neck Cancer	CCLE	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.E9324D	PCI-38	upper aerodigestive tract	COSMIC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.3056
p.R1189Q	SIDM01154	T-Lymphoblastic Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.1389
p.R1189Q	ACH-000953	Leukemia	CCLE	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.1389
p.R1189Q	SUP-T1	haematopoietic and lymphoid tissue	COSMIC	PSTTS	DEG_SPOP_SBC_1	1196:1200	Mutation rewiring degron network	0.1389
p.S9329R	SIDM00180	Kidney Carcinoma	GDSC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.7427
p.S9329R	SIDM01645	Non-Cancerous	GDSC	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation altering degron motif	0.7427
p.T3544I	SIDM01134	Small Cell Lung Carcinoma	GDSC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1944
p.T3544I	ACH-000292	Lung Cancer	CCLE	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1944
p.T3544I	NCI-H841	lung	COSMIC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.1944
p.T3459S	SIDM00761	Small Cell Lung Carcinoma	GDSC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation altering degron motif	0.6005
p.T3459S	ACH-000752	Lung Cancer	CCLE	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation altering degron motif	0.6005
p.T3459S	NCI-H196	lung	COSMIC	AQTTS	DEG_SPOP_SBC_1	3456:3460	Mutation altering degron motif	0.6005
p.T8678A	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation altering degron motif	0.6028
p.T8678A	ACH-000914	Lymphoma	CCLE	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation altering degron motif	0.6028
p.T8678A	HT	haematopoietic and lymphoid tissue	COSMIC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation altering degron motif	0.6028
p.S1734F	SIDM00156	Neuroblastoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1734F	ACH-002285	Neuroblastoma	CCLE	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.S1734F	NB7	autonomic ganglia	COSMIC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation altering degron motif	0.7982
p.T10344S	SIDM00719	Small Cell Lung Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.0833
p.T10344S	ACH-001364	Lung Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.0833
p.T10344S	NCI-H345	lung	COSMIC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.0833
p.V8979I	SIDM00719	Small Cell Lung Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1667
p.V8979I	ACH-001364	Lung Cancer	CCLE	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1667
p.V8979I	NCI-H345	lung	COSMIC	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation rewiring degron network	0.1667
p.T1752A	SIDM00317	Kidney Carcinoma	GDSC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation altering degron motif	0.7139
p.T1752A	ACH-000171	Kidney Cancer	CCLE	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation altering degron motif	0.7139
p.T1752A	VMRC-RCZ	kidney	COSMIC	PLTSS	DEG_SPOP_SBC_1	1750:1754	Mutation altering degron motif	0.7139
p.L506P	SIDM00523	Small Cell Lung Carcinoma	GDSC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.2778
p.L506P	DMS-53	lung	COSMIC	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.2778
p.F8106S	SIDM01120	Other Solid Cancers	GDSC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2222
p.F8106S	ACH-002174	Lung Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2222
p.F8106S	NCI-H720	lung	COSMIC	VSTST	DEG_SPOP_SBC_1	8098:8102	Mutation rewiring degron network	0.2222
p.R13287W	SIDM01716	Non-Cancerous	GDSC	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.25
p.R13287W	SIDM00175	Melanoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.25
p.R13287W	ACH-002096	Skin Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.25
p.R13287W	ACH-002346	Non-Cancerous	CCLE	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.25
p.P12823S	SIDM01196	Hepatocellular Carcinoma	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.6752
p.P12823S	ACH-000422	Liver Cancer	CCLE	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.6752
p.P12823S	SNU-475	liver	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation altering degron motif	0.6752
p.L888M	SIDM00708	Non-Small Cell Lung Carcinoma	GDSC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.5999
p.L888M	ACH-000841	Lung Cancer	CCLE	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.5999
p.L888M	NCI-H2087	lung	COSMIC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation altering degron motif	0.5999
p.D1817N	SIDM01060	Melanoma	GDSC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1111
p.D1817N	SIDM01060	Melanoma	GDSC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.2778
p.D1817N	ACH-000882	Skin Cancer	CCLE	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1111
p.D1817N	ACH-000882	Skin Cancer	CCLE	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.2778
p.D1817N	IGR-1	skin	COSMIC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation rewiring degron network	0.1111
p.D1817N	IGR-1	skin	COSMIC	PSPTPSME	DEG_SCF_FBW7_2	1819:1826	Mutation rewiring degron network	0.2778
p.A9520T	SIDM00854	Burkitt's Lymphoma	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.A9520T	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.A9520T	SIDM00673	Breast Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	9523:9527	Mutation rewiring degron network	0.25
p.S8271Y	SIDM00223	Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.2778
p.S8271Y	ACH-002144	Lung Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.2778
p.S8271Y	IST-SL1	lung	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.2778
p.S12046N	SIDM00333	Endometrial Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation altering degron motif	0.7069
p.S12046N	ACH-000988	Endometrial/Uterine Cancer	CCLE	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation altering degron motif	0.7069
p.S12046N	MFE-319	endometrium	COSMIC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation altering degron motif	0.7069
p.L10768F	SIDM00562	Breast Carcinoma	GDSC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1667
p.L10768F	ACH-002163	Breast Cancer	CCLE	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1667
p.L10768F	MRK-nu-1	breast	COSMIC	AQTSS	DEG_SPOP_SBC_1	10774:10778	Mutation rewiring degron network	0.1667
p.K4789N	SIDM00562	Breast Carcinoma	GDSC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation substituting flanking lysine	0.25
p.K4789N	ACH-002163	Breast Cancer	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation substituting flanking lysine	0.25
p.K4789N	MRK-nu-1	breast	COSMIC	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation substituting flanking lysine	0.25
p.V11502F	SIDM01110	Hepatocellular Carcinoma	GDSC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.V11502F	SK-HEP-1	liver	COSMIC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.3056
p.T9009A	SIDM00265	Ewing's Sarcoma	GDSC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.2778
p.T9009A	ES3	bone	COSMIC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.2778
p.M6048T	SIDM00681	Colorectal Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1944
p.M6048T	SIDM01641	Non-Cancerous	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.1944
p.K142R	SIDM00753	Squamous Cell Lung Carcinoma	GDSC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation substituting flanking lysine	0.1944
p.K142R	ACH-000781	Lung Cancer	CCLE	VETTS	DEG_SPOP_SBC_1	151:155	Mutation substituting flanking lysine	0.1944
p.K142R	NCI-H2023	lung	COSMIC	VETTS	DEG_SPOP_SBC_1	151:155	Mutation substituting flanking lysine	0.1944
p.V562A	SIDM00683	Prostate Carcinoma	GDSC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0833
p.V562A	LNCaP-Clone-FGC	prostate	COSMIC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation rewiring degron network	0.0833
p.P5657L	SIDM00739	Non-Small Cell Lung Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0833
p.P5657L	ACH-000675	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0833
p.P5657L	NCI-H1734	lung	COSMIC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.0833
p.E8993D	SIDM00983	Bladder Carcinoma	GDSC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.E8993D	SIDM00254	Neuroblastoma	GDSC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.E8993D	ACH-000896	Bladder Cancer	CCLE	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.E8993D	ACH-002283	Neuroblastoma	CCLE	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.E8993D	NB5	autonomic ganglia	COSMIC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.E8993D	647-V	urinary tract	COSMIC	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.1389
p.S11056C	SIDM01056	Breast Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.S11056C	ACH-000330	Breast Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.S11056C	EFM-19	breast	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1667
p.H5238Y	SIDM01056	Breast Carcinoma	GDSC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1389
p.H5238Y	ACH-000330	Breast Cancer	CCLE	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1389
p.H5238Y	EFM-19	breast	COSMIC	VNSSS	DEG_SPOP_SBC_1	5227:5231	Mutation rewiring degron network	0.1389
p.S13600I	SIDM00888	Other Solid Cancers	GDSC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.S13600I	ACH-000055	Brain Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.S13600I	D-283MED	central nervous system	COSMIC	VPTTS	DEG_SPOP_SBC_1	13602:13606	Mutation rewiring degron network	0.2778
p.S3974P	SIDM01045	Endometrial Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1389
p.S3974P	ACH-000978	Endometrial/Uterine Cancer	CCLE	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1389
p.S3974P	EN	endometrium	COSMIC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1389
p.K9283R	SIDM00704	Small Cell Lung Carcinoma	GDSC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation substituting flanking lysine	0.1667
p.K9283R	ACH-000639	Lung Cancer	CCLE	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation substituting flanking lysine	0.1667
p.K9283R	NCI-H211	lung	COSMIC	LTSTPAFS	DEG_SCF_FBW7_1	9266:9273	Mutation substituting flanking lysine	0.1667
p.S8160F	SIDM00853	Other Sarcomas	GDSC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.9093
p.S8160F	ACH-000835	Sarcoma	CCLE	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.9093
p.S8160F	GCT	soft tissue	COSMIC	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation altering degron motif	0.9093
p.S7782F	SIDM00853	Other Sarcomas	GDSC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.3056
p.S7782F	ACH-000835	Sarcoma	CCLE	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.3056
p.S7782F	GCT	soft tissue	COSMIC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation rewiring degron network	0.3056
p.S11C	SIDM00587	Biliary Tract Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	SIDM00359	Colorectal Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	SIDM01372	Pancreatic Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	SIDM01511	Gastric Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	SIDM01448	Head and Neck Carcinoma	GDSC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	RCM-1	large intestine	COSMIC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S11C	HuCCT1	biliary tract	COSMIC	PGSSS	DEG_SPOP_SBC_1	8:12	Mutation altering degron motif	0.8652
p.S10540L	SIDM00871	Non-Cancerous	GDSC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.3056
p.S10540L	SIDM00871	Non-Cancerous	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1389
p.S10540L	SIDM00872	Breast Carcinoma	GDSC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.3056
p.S10540L	SIDM00872	Breast Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1389
p.S10540L	ACH-000859	Breast Cancer	CCLE	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.3056
p.S10540L	ACH-000859	Breast Cancer	CCLE	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1389
p.S10540L	ACH-002384	Non-Cancerous	CCLE	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.3056
p.S10540L	ACH-002384	Non-Cancerous	CCLE	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1389
p.T11819S	SIDM00487	Colorectal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1389
p.T11819S	ACH-000963	Colon/Colorectal Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1389
p.T11819S	CCK-81	large intestine	COSMIC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1389
p.Q3111P	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.Q3111P	SIDM00673	Breast Carcinoma	GDSC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.2778
p.L2465I	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2778
p.L2465I	H513	pleura	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2778
p.P2995A	SIDM00511	Small Cell Lung Carcinoma	GDSC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995A	ACH-000257	Lung Cancer	CCLE	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.P2995A	COR-L279	lung	COSMIC	AMTST	DEG_SPOP_SBC_1	3003:3007	Mutation rewiring degron network	0.1111
p.T10336N	SIDM00290	Gastric Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.3056
p.T10336N	ACH-000847	Gastric Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.3056
p.T10336N	HGC-27	stomach	COSMIC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.3056
p.R704G	SIDM00250	Esophageal Squamous Cell Carcinoma	GDSC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.R704G	ACH-000917	Esophageal Cancer	CCLE	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.R704G	TE-4	oesophagus	COSMIC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.3056
p.P12984L	SIDM00931	Thyroid Gland Carcinoma	GDSC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	SIDM00931	Thyroid Gland Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.P12984L	SIDM00861	Ovarian Carcinoma	GDSC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	SIDM00861	Ovarian Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.P12984L	ACH-000174	Thyroid Cancer	CCLE	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	ACH-000174	Thyroid Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.P12984L	ACH-000906	Ovarian Cancer	CCLE	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	ACH-000906	Ovarian Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.P12984L	CAL-62	thyroid	COSMIC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	CAL-62	thyroid	COSMIC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.P12984L	ES-2	ovary	COSMIC	PTSTPGTS	DEG_SCF_FBW7_1	12980:12987	Mutation altering degron motif	0.7582
p.P12984L	ES-2	ovary	COSMIC	PGTST	DEG_SPOP_SBC_1	12984:12988	Mutation altering degron motif	0.7582
p.S7807N	SIDM00710	Small Cell Lung Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.S7807N	ACH-000394	Lung Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.S7807N	NCI-H2081	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.3056
p.S9540A	SIDM00046	Non-Small Cell Lung Carcinoma	GDSC	VVTSS	DEG_SPOP_SBC_1	9549:9553	Mutation rewiring degron network	0.0833
p.P2458S	SIDM00221	Melanoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.P2458S	ACH-002388	Skin Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.T8284I	SIDM00653	Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1389
p.T8284I	ACH-000514	Lung Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1389
p.T8284I	NCI-H1092	lung	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1389
p.L11578F	SIDM00516	Melanoma	GDSC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2222
p.L11578F	ACH-002166	Skin Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2222
p.L11578F	MZ7-mel	skin	COSMIC	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2222
p.P11398S	SIDM00516	Melanoma	GDSC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.5641
p.P11398S	ACH-002166	Skin Cancer	CCLE	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.5641
p.P11398S	MZ7-mel	skin	COSMIC	TVSPDVPDM	DEG_COP1_1	11395:11403	Mutation altering degron motif	0.5641
p.V11743E	SIDM01986	Non-Small Cell Lung Carcinoma	GDSC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0833
p.T7722N	SIDM00299	Other Sarcomas	GDSC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.T7722N	ACH-002271	Sarcoma	CCLE	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.T7722N	MFH-ino	soft tissue	COSMIC	PATTT	DEG_SPOP_SBC_1	7725:7729	Mutation rewiring degron network	0.25
p.M8699V	SIDM00493	Other Solid Cancers	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1111
p.M8699V	SIDM00032	Bladder Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1111
p.M8699V	SIDM00621	Ewing's Sarcoma	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1111
p.M8699V	SIDM00954	Breast Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1111
p.Q10453E	SIDM01157	Other Solid Cancers	GDSC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation altering degron motif	0.5633
p.Q10453E	SW954	vulva	COSMIC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation altering degron motif	0.5633
p.S1481P	SIDM00498	Colorectal Carcinoma	GDSC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.S1481P	ACH-000970	Colon/Colorectal Cancer	CCLE	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.S1481P	SNU-C5	large intestine	COSMIC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.0556
p.V13769A	SIDM00365	Small Cell Lung Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.1389
p.V13769A	ACH-002196	Lung Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.1389
p.V13769A	SBC-1	lung	COSMIC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.1389
p.D12365H	SIDM00365	Small Cell Lung Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.1111
p.D12365H	SIDM00365	Small Cell Lung Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2778
p.D12365H	ACH-002196	Lung Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.1111
p.D12365H	ACH-002196	Lung Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2778
p.D12365H	SBC-1	lung	COSMIC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation rewiring degron network	0.1111
p.D12365H	SBC-1	lung	COSMIC	PGTST	DEG_SPOP_SBC_1	12359:12363	Mutation rewiring degron network	0.2778
p.V12210L	SIDM00792	Small Cell Lung Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1111
p.V12210L	SIDM00792	Small Cell Lung Carcinoma	GDSC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.25
p.V12210L	ACH-002170	Lung Cancer	CCLE	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1111
p.V12210L	ACH-002170	Lung Cancer	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.25
p.V12210L	NCI-H1688	lung	COSMIC	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation rewiring degron network	0.1111
p.V12210L	NCI-H1688	lung	COSMIC	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.25
p.P10833L	SIDM00181	Bladder Carcinoma	GDSC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.P10833L	SIDM01646	Non-Cancerous	GDSC	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.P10833L	ACH-002358	Non-Cancerous	CCLE	PWTTS	DEG_SPOP_SBC_1	10836:10840	Mutation rewiring degron network	0.25
p.S10023C	SIDM00478	Esophageal Squamous Cell Carcinoma	GDSC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023C	ACH-000544	Esophageal Cancer	CCLE	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.S10023C	OE21	oesophagus	COSMIC	PVTTS	DEG_SPOP_SBC_1	10028:10032	Mutation rewiring degron network	0.1944
p.T3717I	SIDM00815	Ovarian Carcinoma	GDSC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2222
p.T3717I	ACH-001418	Ovarian Cancer	CCLE	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2222
p.T3717I	UWB1_289	ovary	COSMIC	PNTPLST	DEG_SCF_FBW7_1	3721:3727	Mutation rewiring degron network	0.2222
p.M8087V	SIDM00254	Neuroblastoma	GDSC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8087V	SIDM01445	Gastric Carcinoma	GDSC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8087V	ACH-000736	Gastric Cancer	CCLE	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8087V	ACH-002283	Neuroblastoma	CCLE	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.M8087V	NB5	autonomic ganglia	COSMIC	VITST	DEG_SPOP_SBC_1	8088:8092	Mutation rewiring degron network	0.3056
p.E6872K	SIDM00254	Neuroblastoma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.E6872K	SIDM00720	Mesothelioma	GDSC	PSTST	DEG_SPOP_SBC_1	6882:6886	Mutation rewiring degron network	0.0556
p.K6604T	SIDM00254	Neuroblastoma	GDSC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation substituting flanking lysine	0.3611
p.K6604T	SIDM00720	Mesothelioma	GDSC	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation substituting flanking lysine	0.3611
p.V6053I	SIDM00254	Neuroblastoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.7076
p.V6053I	SIDM00720	Mesothelioma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation altering degron motif	0.7076
p.H2457Q	SIDM00254	Neuroblastoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2778
p.H2457Q	ACH-002283	Neuroblastoma	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2778
p.H2457Q	NB5	autonomic ganglia	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.2778
p.G46D	SIDM00254	Neuroblastoma	GDSC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.3056
p.G46D	SIDM00720	Mesothelioma	GDSC	PKTST	DEG_SPOP_SBC_1	41:45	Mutation rewiring degron network	0.3056
p.P8317H	SIDM00214	Colorectal Carcinoma	GDSC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation altering degron motif	0.7694
p.P8317H	ACH-000955	Colon/Colorectal Cancer	CCLE	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation altering degron motif	0.7694
p.P8317H	SNU-407	large intestine	COSMIC	PGTSS	DEG_SPOP_SBC_1	8317:8321	Mutation altering degron motif	0.7694
p.P10448S	SIDM00242	Osteosarcoma	GDSC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.P10448S	SIDM01498	Acute Myeloid Leukemia	GDSC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.P10448S	ACH-000487	Leukemia	CCLE	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.P10448S	ACH-002067	Bone Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.P10448S	NOS-1	bone	COSMIC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.2222
p.T4030I	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1944
p.T4030I	ACH-000886	Lung Cancer	CCLE	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1944
p.T4030I	NCI-H2009	lung	COSMIC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation rewiring degron network	0.1944
p.S11745L	SIDM00146	Breast Carcinoma	GDSC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.S11745L	SIDM00146	Breast Carcinoma	GDSC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation blocking phosphorylation signal	0.5833
p.S11745L	ACH-000768	Breast Cancer	CCLE	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.S11745L	ACH-000768	Breast Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation blocking phosphorylation signal	0.5833
p.S11745L	MDA-MB-231	breast	COSMIC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.S11745L	MDA-MB-231	breast	COSMIC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation blocking phosphorylation signal	0.5833
p.P710H	SIDM01127	Non-Small Cell Lung Carcinoma	GDSC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1389
p.P710H	ACH-000628	Lung Cancer	CCLE	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1389
p.P710H	NCI-H596	lung	COSMIC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation rewiring degron network	0.1389
p.Q2715K	SIDM00339	Non-Small Cell Lung Carcinoma	GDSC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.0833
p.Q2715K	ACH-000787	Lung Cancer	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.0833
p.Q2715K	LXF-289	lung	COSMIC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.0833
p.P700L	SIDM01066	Melanoma	GDSC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation altering degron motif	0.7582
p.P700L	ACH-000650	Skin Cancer	CCLE	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation altering degron motif	0.7582
p.P700L	IGR-37	skin	COSMIC	LGLTPLNT	DEG_SCF_FBW7_1	696:703	Mutation altering degron motif	0.7582
p.P3117L	SIDM00140	Melanoma	GDSC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.7582
p.P3117L	ACH-000968	Skin Cancer	CCLE	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.7582
p.P3117L	COLO-792	skin	COSMIC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation altering degron motif	0.7582
p.T2727A	SIDM01019	Acute Myeloid Leukemia	GDSC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7139
p.T2727A	ACH-002258	Leukemia	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7139
p.T2727A	KMOE-2	haematopoietic and lymphoid tissue	COSMIC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation altering degron motif	0.7139
p.N4606K	SIDM01190	Bladder Carcinoma	GDSC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation altering degron motif	0.6918
p.P10866S	SIDM00752	Non-Cancerous	GDSC	ESSSAVPTP	DEG_COP1_1	10860:10868	Mutation altering degron motif	0.6752
p.P10866S	SIDM00752	Non-Cancerous	GDSC	VPTPTVS	DEG_SCF_FBW7_1	10865:10871	Mutation altering degron motif	0.5641
p.W11238L	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238L	SIDM00927	Small Cell Lung Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238L	ACH-000694	Esophageal Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238L	ACH-000871	Lung Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238L	NCI-H510A	lung	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.W11238L	TE-9	oesophagus	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation rewiring degron network	0.1667
p.I3991M	SIDM00927	Small Cell Lung Carcinoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1667
p.I3991M	ACH-000871	Lung Cancer	CCLE	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1667
p.I3991M	NCI-H510A	lung	COSMIC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.1667
p.V6333A	SIDM01052	Ovarian Carcinoma	GDSC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.5825
p.V6333A	ACH-000308	Ovarian Cancer	CCLE	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.5825
p.V6333A	EFO-21	ovary	COSMIC	VITST	DEG_SPOP_SBC_1	6333:6337	Mutation altering degron motif	0.5825
p.K11955E	SIDM00438	B-Lymphoblastic Leukemia	GDSC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation altering degron motif	0.591
p.K11955E	ACH-002275	Leukemia	CCLE	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation altering degron motif	0.591
p.K11955E	MN-60	haematopoietic and lymphoid tissue	COSMIC	MPTPPKT	DEG_SCF_FBW7_1	11950:11956	Mutation altering degron motif	0.591
p.T11894A	SIDM00537	Colorectal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1667
p.T11894A	GP5d	large intestine	COSMIC	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation rewiring degron network	0.1667
p.S11512G	SIDM00537	Colorectal Carcinoma	GDSC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.S11512G	ACH-000982	Colon/Colorectal Cancer	CCLE	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.S11512G	ACH-001345	Colon/Colorectal Cancer	CCLE	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.S11512G	GP5d	large intestine	COSMIC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.2778
p.T879I	SIDM00537	Colorectal Carcinoma	GDSC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1389
p.T879I	ACH-000982	Colon/Colorectal Cancer	CCLE	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1389
p.T879I	ACH-001345	Colon/Colorectal Cancer	CCLE	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1389
p.T879I	GP5d	large intestine	COSMIC	TTLASTSVPTP	DEG_COP1_1	886:896	Mutation rewiring degron network	0.1389
p.R4929K	SIDM00740	Squamous Cell Lung Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.25
p.R4929K	ACH-000747	Lung Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.25
p.R4929K	NCI-H1703	lung	COSMIC	VTSSS	DEG_SPOP_SBC_1	4932:4936	Mutation rewiring degron network	0.25
p.L9735V	SIDM00989	Bladder Carcinoma	GDSC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.5654
p.L9735V	ACH-000802	Bladder Cancer	CCLE	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.5654
p.L9735V	BFTC-905	urinary tract	COSMIC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation altering degron motif	0.5654
p.P12673L	SIDM00508	Squamous Cell Lung Carcinoma	GDSC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.P12673L	ACH-001489	Lung Cancer	CCLE	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.P12673L	COR-L32	lung	COSMIC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.2778
p.V11052L	SIDM01133	Other Solid Cancers	GDSC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2778
p.V11052L	ACH-002177	Lung Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2778
p.V11052L	NCI-H835	lung	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.2778
p.T463S	SIDM00324	Neuroblastoma	GDSC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2222
p.T463S	ACH-001674	Neuroblastoma	CCLE	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2222
p.T463S	TGW	autonomic ganglia	COSMIC	EESEMTATLVPTL	DEG_COP1_1	447:459	Mutation rewiring degron network	0.2222
p.Q11746E	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1111
p.Q11746E	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.1667
p.Q11746E	KYSE-450	oesophagus	COSMIC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1111
p.Q11746E	KYSE-450	oesophagus	COSMIC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.1667
p.Q11817H	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.Q11817H	ACH-000900	Lung Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.Q11817H	NCI-H23	lung	COSMIC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.N12037K	SIDM00930	Osteosarcoma	GDSC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1667
p.N12037K	ACH-001715	Bone Cancer	CCLE	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1667
p.N12037K	CAL-72	bone	COSMIC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1667
p.T3234K	SIDM00930	Osteosarcoma	GDSC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.6195
p.T3234K	ACH-001715	Bone Cancer	CCLE	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.6195
p.T3234K	CAL-72	bone	COSMIC	PWKTPETT	DEG_SCF_FBW7_1	3228:3235	Mutation altering degron motif	0.6195
p.T2454K	SIDM00930	Osteosarcoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation blocking phosphorylation signal	0.6389
p.T2454K	ACH-001715	Bone Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation blocking phosphorylation signal	0.6389
p.T2454K	CAL-72	bone	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation blocking phosphorylation signal	0.6389
p.T11310N	SIDM01158	Squamous Cell Lung Carcinoma	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.7055
p.T11310N	ACH-000669	Lung Cancer	CCLE	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.7055
p.T11310N	SW900	lung	COSMIC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation altering degron motif	0.7055
p.P10329H	SIDM00217	Colorectal Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.P10329H	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.P10329H	ACH-000869	Lung Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.P10329H	ACH-000999	Colon/Colorectal Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.P10329H	SNU-1040	large intestine	COSMIC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.P10329H	NCI-H1568	lung	COSMIC	PFSSS	DEG_SPOP_SBC_1	10331:10335	Mutation rewiring degron network	0.2778
p.A6768T	SIDM00217	Colorectal Carcinoma	GDSC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1111
p.A6768T	ACH-000999	Colon/Colorectal Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1111
p.A6768T	SNU-1040	large intestine	COSMIC	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.1111
p.V4480A	SIDM00217	Colorectal Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0556
p.V4480A	ACH-000999	Colon/Colorectal Cancer	CCLE	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0556
p.V4480A	SNU-1040	large intestine	COSMIC	PATST	DEG_SPOP_SBC_1	4466:4470	Mutation rewiring degron network	0.0556
p.P1829S	SIDM00217	Colorectal Carcinoma	GDSC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.6752
p.P1829S	ACH-000999	Colon/Colorectal Cancer	CCLE	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.6752
p.P1829S	SNU-1040	large intestine	COSMIC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.6752
p.S1502P	SIDM00217	Colorectal Carcinoma	GDSC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2222
p.S1502P	ACH-000999	Colon/Colorectal Cancer	CCLE	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2222
p.S1502P	SNU-1040	large intestine	COSMIC	PMSTPSHE	DEG_SCF_FBW7_2	1491:1498	Mutation rewiring degron network	0.2222
p.T10879P	SIDM00863	Burkitt's Lymphoma	GDSC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.7031
p.T10879P	ACH-001064	Lymphoma	CCLE	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.7031
p.T10879P	EB2	haematopoietic and lymphoid tissue	COSMIC	VVTPLVT	DEG_SCF_FBW7_1	10877:10883	Mutation altering degron motif	0.7031
p.P7983T	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.3056
p.P7983T	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.2778
p.P7983T	ACH-000672	Lung Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.3056
p.P7983T	ACH-000672	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.2778
p.P7983T	IA-LM	lung	COSMIC	PATTS	DEG_SPOP_SBC_1	7978:7982	Mutation rewiring degron network	0.3056
p.P7983T	IA-LM	lung	COSMIC	PVSST	DEG_SPOP_SBC_1	7985:7989	Mutation rewiring degron network	0.2778
p.H9807N	SIDM00534	Colorectal Carcinoma	GDSC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807N	ACH-000986	Colon/Colorectal Cancer	CCLE	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.H9807N	HT-115	large intestine	COSMIC	VRTSS	DEG_SPOP_SBC_1	9817:9821	Mutation rewiring degron network	0.0556
p.N930H	SIDM00534	Colorectal Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.2222
p.N930H	ACH-000986	Colon/Colorectal Cancer	CCLE	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.2222
p.N930H	HT-115	large intestine	COSMIC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.2222
p.L10792W	SIDM00361	Non-Small Cell Lung Carcinoma	GDSC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.0556
p.L10792W	PC-3_[JPC-3]	lung	COSMIC	AKTST	DEG_SPOP_SBC_1	10802:10806	Mutation rewiring degron network	0.0556
p.T10556K	SIDM00579	Neuroblastoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.T10556K	ACH-002277	Neuroblastoma	CCLE	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.T10556K	NB(TU)1-10	autonomic ganglia	COSMIC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.S11755N	SIDM01128	Small Cell Lung Carcinoma	GDSC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7069
p.S11755N	SIDM01128	Small Cell Lung Carcinoma	GDSC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.7069
p.S11755N	ACH-000767	Lung Cancer	CCLE	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7069
p.S11755N	ACH-000767	Lung Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.7069
p.S11755N	NCI-H526	lung	COSMIC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation altering degron motif	0.7069
p.S11755N	NCI-H526	lung	COSMIC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.7069
p.A10542S	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.25
p.A10542S	SIDM00743	Non-Small Cell Lung Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.A10542S	ACH-000448	Lung Cancer	CCLE	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.25
p.A10542S	ACH-000448	Lung Cancer	CCLE	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.A10542S	NCI-H1666	lung	COSMIC	PETTS	DEG_SPOP_SBC_1	10535:10539	Mutation rewiring degron network	0.25
p.A10542S	NCI-H1666	lung	COSMIC	AETST	DEG_SPOP_SBC_1	10547:10551	Mutation rewiring degron network	0.1944
p.H12818R	SIDM01012	Other Blood Cancers	GDSC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1944
p.H12818R	SIDM01012	Other Blood Cancers	GDSC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.0556
p.H12818R	ACH-000346	Leukemia	CCLE	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1944
p.H12818R	ACH-000346	Leukemia	CCLE	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.0556
p.H12818R	JVM-3	haematopoietic and lymphoid tissue	COSMIC	PNTST	DEG_SPOP_SBC_1	12823:12827	Mutation rewiring degron network	0.1944
p.H12818R	JVM-3	haematopoietic and lymphoid tissue	COSMIC	PGTST	DEG_SPOP_SBC_1	12828:12832	Mutation rewiring degron network	0.0556
p.T11803N	SIDM00220	Ovarian Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.T11803N	ACH-000962	Ovarian Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.T11803N	ACH-001145	Ovarian Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.T11803N	OC-314	ovary	COSMIC	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1944
p.P5637H	SIDM00554	Ovarian Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.P5637H	SIDM01739	Small Cell Lung Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.P5637H	ACH-000297	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.P5637H	ACH-000524	Ovarian Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.P5637H	KURAMOCHI	ovary	COSMIC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.S354T	SIDM00870	Breast Carcinoma	GDSC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6005
p.S354T	ACH-000725	Breast Cancer	CCLE	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6005
p.S354T	ACH-001068	Lymphoma	CCLE	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6005
p.S354T	HCC202	breast	COSMIC	LGTPSIS	DEG_SCF_FBW7_1	350:356	Mutation altering degron motif	0.6005
p.W10683C	SIDM00118	Colorectal Carcinoma	GDSC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.W10683C	ACH-001081	Colon/Colorectal Cancer	CCLE	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.W10683C	HCC2998	large intestine	COSMIC	AETSS	DEG_SPOP_SBC_1	10688:10692	Mutation rewiring degron network	0.1944
p.S4021N	SIDM00118	Colorectal Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.5958
p.S4021N	ACH-001081	Colon/Colorectal Cancer	CCLE	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.5958
p.S4021N	HCC2998	large intestine	COSMIC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.5958
p.P11251S	SIDM00056	Thyroid Gland Carcinoma	GDSC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6752
p.P11251S	ACH-002148	Thyroid Cancer	CCLE	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6752
p.P11251S	K5	thyroid	COSMIC	TEASSVVPTL	DEG_COP1_1	11244:11253	Mutation altering degron motif	0.6752
p.T5613A	SIDM00783	Colorectal Carcinoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.T5613A	ACH-000971	Colon/Colorectal Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.T5613A	HCT-116	large intestine	COSMIC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation rewiring degron network	0.1389
p.P5359T	SIDM00783	Colorectal Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.P5359T	ACH-000971	Colon/Colorectal Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.P5359T	HCT-116	large intestine	COSMIC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation rewiring degron network	0.1667
p.T222I	SIDM00783	Colorectal Carcinoma	GDSC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation blocking phosphorylation signal	0.5833
p.T222I	ACH-000971	Colon/Colorectal Cancer	CCLE	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation blocking phosphorylation signal	0.5833
p.T222I	HCT-116	large intestine	COSMIC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation blocking phosphorylation signal	0.5833
p.S8283F	SIDM00528	Breast Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1667
p.S8283F	ACH-000934	Breast Cancer	CCLE	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1667
p.S8283F	MDA-MB-361	breast	COSMIC	PATTS	DEG_SPOP_SBC_1	8273:8277	Mutation rewiring degron network	0.1667
p.D5757G	SIDM00451	T-Lymphoblastic Leukemia	GDSC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.D5757G	PF-382	haematopoietic and lymphoid tissue	COSMIC	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.25
p.P11985L	SIDM00867	Glioblastoma	GDSC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.25
p.P11985L	ACH-000863	Brain Cancer	CCLE	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.25
p.P11985L	DBTRG-05MG	central nervous system	COSMIC	AKTTT	DEG_SPOP_SBC_1	11988:11992	Mutation rewiring degron network	0.25
p.T5455I	SIDM00867	Glioblastoma	GDSC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.0833
p.T5455I	ACH-000863	Brain Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.0833
p.T5455I	DBTRG-05MG	central nervous system	COSMIC	VSTST	DEG_SPOP_SBC_1	5464:5468	Mutation rewiring degron network	0.0833
p.T3574S	SIDM00867	Glioblastoma	GDSC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.T3574S	ACH-000863	Brain Cancer	CCLE	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.T3574S	DBTRG-05MG	central nervous system	COSMIC	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation rewiring degron network	0.25
p.S1832F	SIDM01059	Melanoma	GDSC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.7982
p.S1832F	ACH-000915	Skin Cancer	CCLE	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.7982
p.S1832F	IPC-298	skin	COSMIC	MEVTPWIS	DEG_SCF_FBW7_1	1825:1832	Mutation altering degron motif	0.7982
p.T11171I	SIDM00150	Colorectal Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1667
p.T11171I	SIDM00150	Colorectal Carcinoma	GDSC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1667
p.T11171I	ACH-000969	Colon/Colorectal Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1667
p.T11171I	ACH-000969	Colon/Colorectal Cancer	CCLE	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1667
p.T11171I	KM12	large intestine	COSMIC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.1667
p.T11171I	KM12	large intestine	COSMIC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.1667
p.A7274V	SIDM00150	Colorectal Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.0833
p.A7274V	ACH-000969	Colon/Colorectal Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.0833
p.A7274V	KM12	large intestine	COSMIC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation rewiring degron network	0.0833
p.R13755W	SIDM00839	Colorectal Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755W	ACH-000950	Colon/Colorectal Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.R13755W	LoVo	large intestine	COSMIC	VSTTS	DEG_SPOP_SBC_1	13758:13762	Mutation rewiring degron network	0.25
p.A1648S	SIDM01140	Ovarian Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.A1648S	ACH-001374	Ovarian Cancer	CCLE	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.A1648S	PA-1	ovary	COSMIC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.S7512C	SIDM00937	Oral Cavity Carcinoma	GDSC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.0556
p.S7512C	CAL-27	upper aerodigestive tract	COSMIC	LTPALS	DEG_SCF_FBW7_1	7522:7527	Mutation rewiring degron network	0.0556
p.V7808F	SIDM00975	Melanoma	GDSC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation altering degron motif	0.7068
p.V7808F	WM278	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation altering degron motif	0.7068
p.P11495H	SIDM00720	Mesothelioma	GDSC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.T215N	SIDM00720	Mesothelioma	GDSC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7055
p.T215N	ACH-000648	Lung Cancer	CCLE	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7055
p.T215N	NCI-H28	pleura	COSMIC	VSMTPAET	DEG_SCF_FBW7_1	208:215	Mutation altering degron motif	0.7055
p.M11742I	SIDM01228	Melanoma	GDSC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0556
p.M11742I	ACH-000931	Skin Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0556
p.M11742I	ACH-001024	Skin Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0556
p.M11742I	CHL-1	skin	COSMIC	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.0556
p.V8687I	SIDM01086	B-Lymphoblastic Leukemia	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7076
p.V8687I	ACH-000874	Leukemia	CCLE	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7076
p.V8687I	RS4-11	haematopoietic and lymphoid tissue	COSMIC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation altering degron motif	0.7076
p.H1964Q	SIDM00808	Burkitt's Lymphoma	GDSC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.0833
p.H1964Q	SIDM01254	Burkitt's Lymphoma	GDSC	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.0833
p.P2458T	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.P2458T	ACH-000869	Lung Cancer	CCLE	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.P2458T	NCI-H1568	lung	COSMIC	VETSS	DEG_SPOP_SBC_1	2459:2463	Mutation rewiring degron network	0.3056
p.T11111K	SIDM01033	Bladder Carcinoma	GDSC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7306
p.T11111K	ACH-000486	Bladder Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7306
p.T11111K	KU-19-19	urinary tract	COSMIC	AVTST	DEG_SPOP_SBC_1	11107:11111	Mutation altering degron motif	0.7306
p.S11050I	SIDM00755	Non-Small Cell Lung Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.7341
p.S11050I	ACH-000888	Lung Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.7341
p.S11050I	NCI-H1793	lung	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation altering degron motif	0.7341
p.S3128F	SIDM00273	Glioblastoma	GDSC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.1111
p.S3128F	ACH-000756	Brain Cancer	CCLE	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.1111
p.S3128F	GI-1	central nervous system	COSMIC	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.1111
p.A7814V	SIDM00859	B-Cell Non-Hodgkin's Lymphoma	GDSC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.2778
p.A7814V	ACH-001498	Lymphoma	CCLE	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.2778
p.A7814V	Farage	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	7808:7812	Mutation rewiring degron network	0.2778
p.T3543I	SIDM00225	Melanoma	GDSC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.T3543I	ACH-002143	Skin Cancer	CCLE	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.T3543I	IST-MEL1	skin	COSMIC	PTPGIS	DEG_SCF_FBW7_1	3534:3539	Mutation rewiring degron network	0.2222
p.S3979F	SIDM01727	Chronic Myelogenous Leukemia	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.2778
p.S3979F	ACH-000241	Leukemia	CCLE	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation rewiring degron network	0.2778
p.S12357N	SIDM01545	Non-Small Cell Lung Carcinoma	GDSC	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation altering degron motif	0.7069
p.S12357N	ACH-000511	Lung Cancer	CCLE	VSTTS	DEG_SPOP_SBC_1	12353:12357	Mutation altering degron motif	0.7069
p.P2735S	SIDM01609	Endometrial Carcinoma	GDSC	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2735S	ACH-000972	Endometrial/Uterine Cancer	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.P2735S	ACH-001852	Bile Duct Cancer	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.1389
p.G11317V	SIDM01608	Endometrial Carcinoma	GDSC	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.G11317V	ACH-000990	Endometrial/Uterine Cancer	CCLE	AISTT	DEG_SPOP_SBC_1	11306:11310	Mutation rewiring degron network	0.1389
p.L2331F	SIDM01659	Kidney Carcinoma	GDSC	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.2222
p.L2331F	ACH-000313	Kidney Cancer	CCLE	APTTS	DEG_SPOP_SBC_1	2323:2327	Mutation rewiring degron network	0.2222
p.L9739I	SIDM01335	Kidney Carcinoma	GDSC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.3056
p.L9739I	SIDM01335	Kidney Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.2778
p.S4021R	SIDM01335	Kidney Carcinoma	GDSC	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6316
p.S4021R	ACH-000513	Kidney Cancer	CCLE	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.6316
p.L9747I	SIDM01511	Gastric Carcinoma	GDSC	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.0833
p.L9747I	SIDM01511	Gastric Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.2778
p.L9747I	ACH-000746	Gastric Cancer	CCLE	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.0833
p.L9747I	ACH-000746	Gastric Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation rewiring degron network	0.2778
p.P5624S	SIDM00167	Head and Neck Carcinoma	GDSC	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.5641
p.P5624S	ACH-000715	Head and Neck Cancer	CCLE	MTTPPVE	DEG_SCF_FBW7_2	5620:5626	Mutation altering degron motif	0.5641
p.P10461S	SIDM01398	Melanoma	GDSC	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.1944
p.P10461S	ACH-000661	Skin Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	10452:10456	Mutation rewiring degron network	0.1944
p.G13919R	SIDM01664	Prostate Carcinoma	GDSC	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.G13919R	ACH-000952	Prostate Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.T3984A	SIDM01766	Chondrosarcoma	GDSC	VVTTS	DEG_SPOP_SBC_1	3981:3985	Mutation altering degron motif	0.7139
p.T11770S	SIDM01660	Kidney Carcinoma	GDSC	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.T11770S	ACH-000709	Kidney Cancer	CCLE	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation blocking phosphorylation signal	0.5278
p.P6061S	SIDM01660	Kidney Carcinoma	GDSC	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.2222
p.T5825S	SIDM01622	Breast Carcinoma	GDSC	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2778
p.T5825S	ACH-000721	Breast Cancer	CCLE	VITSS	DEG_SPOP_SBC_1	5819:5823	Mutation rewiring degron network	0.2778
p.P5637T	SIDM01739	Small Cell Lung Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.P5637T	ACH-000297	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5644:5648	Mutation rewiring degron network	0.1389
p.M8698L	SIDM01693	B-Lymphoblastic Leukemia	GDSC	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1389
p.M8698L	ACH-000032	Leukemia	CCLE	VSTST	DEG_SPOP_SBC_1	8687:8691	Mutation rewiring degron network	0.1389
p.P9164T	SIDM01628	Non-Small Cell Lung Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.P9164T	ACH-000851	Lung Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.2778
p.E2089D	SIDM01397	Melanoma	GDSC	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089D	SIDM01397	Melanoma	GDSC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.E2089D	ACH-000765	Skin Cancer	CCLE	PSSTT	DEG_SPOP_SBC_1	2083:2087	Mutation rewiring degron network	0.2778
p.E2089D	ACH-000765	Skin Cancer	CCLE	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1667
p.T7780P	SIDM01611	Endometrial Carcinoma	GDSC	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation altering degron motif	0.7031
p.T7780P	ACH-000996	Endometrial/Uterine Cancer	CCLE	VATTS	DEG_SPOP_SBC_1	7777:7781	Mutation altering degron motif	0.7031
p.A550S	SIDM01611	Endometrial Carcinoma	GDSC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation altering degron motif	0.6477
p.A550S	ACH-000996	Endometrial/Uterine Cancer	CCLE	PASTS	DEG_SPOP_SBC_1	549:553	Mutation altering degron motif	0.6477
p.T13139P	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	TSGTPSPVPSP	DEG_COP1_1	13149:13159	Mutation rewiring degron network	0.0556
p.T13139P	SIDM01758	B-Cell Non-Hodgkin's Lymphoma	GDSC	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.3056
p.T5353S	SIDM01464	Pancreatic Carcinoma	GDSC	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.6005
p.T5353S	ACH-000502	Pancreatic Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	5349:5353	Mutation altering degron motif	0.6005
p.P2106S	SIDM01768	Melanoma	GDSC	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.P2106S	ACH-000899	Skin Cancer	CCLE	AASTS	DEG_SPOP_SBC_1	2095:2099	Mutation rewiring degron network	0.1389
p.D11175N	SIDM01640	Acute Myeloid Leukemia	GDSC	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.D11175N	SIDM01640	Acute Myeloid Leukemia	GDSC	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2778
p.D11175N	ACH-000602	Leukemia	CCLE	AVTST	DEG_SPOP_SBC_1	11161:11165	Mutation rewiring degron network	0.0556
p.D11175N	ACH-000602	Leukemia	CCLE	PETTT	DEG_SPOP_SBC_1	11177:11181	Mutation rewiring degron network	0.2778
p.L936P	SIDM01778	B-Cell Non-Hodgkin's Lymphoma	GDSC	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0556
p.L936P	ACH-000158	Lymphoma	CCLE	ATSST	DEG_SPOP_SBC_1	922:926	Mutation rewiring degron network	0.0556
p.P549A	SIDM01321	Pancreatic Carcinoma	GDSC	PASTS	DEG_SPOP_SBC_1	549:553	Mutation altering degron motif	0.6392
p.P549A	ACH-000307	Pancreatic Cancer	CCLE	PASTS	DEG_SPOP_SBC_1	549:553	Mutation altering degron motif	0.6392
p.V7283A	SIDM01378	Ovarian Carcinoma	GDSC	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation altering degron motif	0.5825
p.V7283A	ACH-000646	Ovarian Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	7283:7287	Mutation altering degron motif	0.5825
p.T1672R	SIDM01491	Colorectal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.T1672R	ACH-000342	Colon/Colorectal Cancer	CCLE	AETST	DEG_SPOP_SBC_1	1658:1662	Mutation rewiring degron network	0.0556
p.S7486G	SIDM01413	Oral Cavity Carcinoma	GDSC	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.6993
p.S7486G	ACH-000630	Head and Neck Cancer	CCLE	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.6993
p.S7486G	ACH-001540	Liposarcoma	CCLE	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.6993
p.S7486G	ACH-002785	Unknown	CCLE	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation altering degron motif	0.6993
p.N1728D	SIDM01588	Endometrial Carcinoma	GDSC	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.2778
p.N1728D	ACH-000993	Endometrial/Uterine Cancer	CCLE	ALSSS	DEG_SPOP_SBC_1	1730:1734	Mutation rewiring degron network	0.2778
p.T7336P	SIDM01473	Plasma Cell Myeloma	GDSC	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7031
p.T7336P	ACH-000541	Myeloma	CCLE	PGSTS	DEG_SPOP_SBC_1	7333:7337	Mutation altering degron motif	0.7031
p.G9255S	SIDM01729	Endometrial Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.0556
p.G9255S	ACH-000909	Endometrial/Uterine Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	9265:9269	Mutation rewiring degron network	0.0556
p.T4596I	SIDM01618	B-Lymphoblastic Leukemia	GDSC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1389
p.T4596I	ACH-000942	Leukemia	CCLE	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1389
p.S8972P	ACH-000068	Lymphoma	CCLE	VVTSS	DEG_SPOP_SBC_1	8969:8973	Mutation altering degron motif	0.6752
p.S13911N	ACH-000110	Gastric Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000117	Breast Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000337	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000427	Gastric Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000587	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000638	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000666	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.S13911N	ACH-000794	Head and Neck Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation rewiring degron network	0.2778
p.L11802V	ACH-000208	Brain Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11808:11812	Mutation rewiring degron network	0.1667
p.V4638A	ACH-000455	Brain Cancer	CCLE	IPTPAQS	DEG_SCF_FBW7_1	4646:4652	Mutation rewiring degron network	0.1111
p.E3421K	ACH-000458	Skin Cancer	CCLE	AYSST	DEG_SPOP_SBC_1	3422:3426	Mutation rewiring degron network	0.3056
p.M10987V	ACH-000502	Pancreatic Cancer	CCLE	AVTST	DEG_SPOP_SBC_1	10997:11001	Mutation rewiring degron network	0.0556
p.D3565Y	ACH-000512	Myeloma	CCLE	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6214
p.L12680R	ACH-000560	Gastric Cancer	CCLE	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0833
p.L12680R	ECC10	stomach	COSMIC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation rewiring degron network	0.0833
p.G13134V	ACH-000563	Lung Cancer	CCLE	PWTST	DEG_SPOP_SBC_1	13140:13144	Mutation rewiring degron network	0.1667
p.V4020I	ACH-000606	Head and Neck Cancer	CCLE	VSPYMD	LIG_APCC_ABBA_1	4020:4025	Mutation altering degron motif	0.5965
p.V6043D	ACH-000659	Lung Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.0556
p.V6043D	ACH-001386	Lung Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	6053:6057	Mutation rewiring degron network	0.0556
p.D9165N	ACH-000836	Head and Neck Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation rewiring degron network	0.25
p.S13917C	ACH-000872	Lung Cancer	CCLE	VPTTS	DEG_SPOP_SBC_1	13913:13917	Mutation altering degron motif	0.7541
p.T5774N	ACH-000884	Skin Cancer	CCLE	VSTST	DEG_SPOP_SBC_1	5760:5764	Mutation rewiring degron network	0.0556
p.Q1982H	ACH-000901	Lung Cancer	CCLE	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.1944
p.Q8171H	ACH-000941	Endometrial/Uterine Cancer	CCLE	VTSSS	DEG_SPOP_SBC_1	8158:8162	Mutation rewiring degron network	0.0833
p.Q8171H	ACH-000941	Endometrial/Uterine Cancer	CCLE	PETST	DEG_SPOP_SBC_1	8176:8180	Mutation rewiring degron network	0.1944
p.H11580N	ACH-000975	Lung Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11582:11586	Mutation rewiring degron network	0.2778
p.S4781F	ACH-000975	Lung Cancer	CCLE	VLTSS	DEG_SPOP_SBC_1	4778:4782	Mutation altering degron motif	0.7982
p.P1161A	ACH-000975	Lung Cancer	CCLE	PTPKVT	DEG_SCF_FBW7_1	1161:1166	Mutation altering degron motif	0.7503
p.W967G	ACH-000987	Skin Cancer	CCLE	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.3056
p.W967G	Mewo	skin	COSMIC	PQSTT	DEG_SPOP_SBC_1	962:966	Mutation rewiring degron network	0.3056
p.N4613T	ACH-000997	Colon/Colorectal Cancer	CCLE	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.N4613T	ACH-001061	Colon/Colorectal Cancer	CCLE	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.N4613T	HCT-15	large intestine	COSMIC	RKENS	DEG_APCC_KENBOX_2	4603:4607	Mutation rewiring degron network	0.1667
p.A11753E	ACH-001030	Bone Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation altering degron motif	0.659
p.S11749R	ACH-001030	Bone Cancer	CCLE	TSTTVPTL	DEG_COP1_1	11754:11761	Mutation rewiring degron network	0.1944
p.S11749R	ACH-001030	Bone Cancer	CCLE	AATST	DEG_SPOP_SBC_1	11752:11756	Mutation rewiring degron network	0.25
p.T11888A	ACH-001061	Colon/Colorectal Cancer	CCLE	AETST	DEG_SPOP_SBC_1	11884:11888	Mutation altering degron motif	0.825
p.H2723N	ACH-001061	Colon/Colorectal Cancer	CCLE	PSSTS	DEG_SPOP_SBC_1	2724:2728	Mutation rewiring degron network	0.3056
p.K1771T	ACH-001130	Lymphoma	CCLE	PTTPDVE	DEG_SCF_FBW7_2	1755:1761	Mutation substituting flanking lysine	0.1667
p.E6314G	ACH-001132	Lymphoma	CCLE	VGTTS	DEG_SPOP_SBC_1	6306:6310	Mutation rewiring degron network	0.2222
p.A6762G	ACH-001163	Kidney Cancer	CCLE	PTTSS	DEG_SPOP_SBC_1	6756:6760	Mutation rewiring degron network	0.2778
p.S13289P	ACH-001197	Lymphoma	CCLE	VPTTS	DEG_SPOP_SBC_1	13290:13294	Mutation rewiring degron network	0.3056
p.S12201I	ACH-001300	Neuroblastoma	CCLE	PTTST	DEG_SPOP_SBC_1	12198:12202	Mutation altering degron motif	0.7341
p.S9740Y	ACH-001388	Breast Cancer	CCLE	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation blocking phosphorylation signal	0.7222
p.S9740Y	ACH-001388	Breast Cancer	CCLE	PVSST	DEG_SPOP_SBC_1	9741:9745	Mutation blocking phosphorylation signal	0.75
p.P12512L	ACH-001390	Breast Cancer	CCLE	VPTSS	DEG_SPOP_SBC_1	12511:12515	Mutation altering degron motif	0.6471
p.E3571Q	ACH-001407	Bladder Cancer	CCLE	MDSTPATE	DEG_SCF_FBW7_2	3564:3571	Mutation altering degron motif	0.6744
p.S6501N	ACH-001411	Bladder Cancer	CCLE	STLTSRVPEY	DEG_COP1_1	6487:6496	Mutation rewiring degron network	0.1944
p.S1854R	ACH-001414	Bladder Cancer	CCLE	VHTSS	DEG_SPOP_SBC_1	1851:1855	Mutation altering degron motif	0.7427
p.T9009N	ACH-001461	Colon/Colorectal Cancer	CCLE	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.2778
p.T9331A	ACH-001577	Leukemia	CCLE	AISSS	DEG_SPOP_SBC_1	9325:9329	Mutation rewiring degron network	0.2778
p.G501E	ACH-001610	Brain Cancer	CCLE	ATTSS	DEG_SPOP_SBC_1	508:512	Mutation rewiring degron network	0.1389
p.T11686R	ACH-001611	Brain Cancer	CCLE	PQTST	DEG_SPOP_SBC_1	11695:11699	Mutation rewiring degron network	0.0833
p.T5797R	ACH-001623	Brain Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.0833
p.S6602P	ACH-001645	Skin Cancer	CCLE	VGTTT	DEG_SPOP_SBC_1	6597:6601	Mutation rewiring degron network	0.3056
p.T10402S	ACH-001664	Gastric Cancer	CCLE	TVTSAYQVPSL	DEG_COP1_1	10409:10419	Mutation rewiring degron network	0.1389
p.G12214E	ACH-001970	Metastasis	CCLE	PGTST	DEG_SPOP_SBC_1	12203:12207	Mutation rewiring degron network	0.1389
p.P7473H	ACH-001977	Primary	CCLE	VGTSS	DEG_SPOP_SBC_1	7482:7486	Mutation rewiring degron network	0.0833
p.S9727F	ACH-001982	Metastasis	CCLE	PLTTS	DEG_SPOP_SBC_1	9734:9738	Mutation rewiring degron network	0.1389
p.T8999I	ACH-001982	Metastasis	CCLE	LTPTPRET	DEG_SCF_FBW7_1	9000:9007	Mutation rewiring degron network	0.3056
p.I1980V	ACH-002011	Eye Cancer	CCLE	VWTST	DEG_SPOP_SBC_1	1973:1977	Mutation rewiring degron network	0.25
p.S3129P	ACH-002026	Endometrial/Uterine Cancer	CCLE	LTFTPSET	DEG_SCF_FBW7_1	3113:3120	Mutation rewiring degron network	0.0833
p.T11523I	ACH-002061	Leukemia	CCLE	AVSTT	DEG_SPOP_SBC_1	11532:11536	Mutation rewiring degron network	0.0833
p.P11366A	ACH-002069	Bone Cancer	CCLE	PRTTPNYS	DEG_SCF_FBW7_1	11362:11369	Mutation altering degron motif	0.7503
p.S12670T	ACH-002261	Neuroblastoma	CCLE	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation altering degron motif	0.6005
p.S12670T	KP-N-YS	autonomic ganglia	COSMIC	VPTSS	DEG_SPOP_SBC_1	12667:12671	Mutation altering degron motif	0.6005
p.E5798G	ACH-002287	Colon/Colorectal Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.1111
p.E5798G	NCI-H630	large intestine	COSMIC	VPTTT	DEG_SPOP_SBC_1	5806:5810	Mutation rewiring degron network	0.1111
p.N12037T	ACH-002309	Sarcoma	CCLE	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1667
p.N12037T	SW684	soft tissue	COSMIC	PATST	DEG_SPOP_SBC_1	12043:12047	Mutation rewiring degron network	0.1667
p.P11495L	ACH-002396	Bone Cancer	CCLE	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.P11495L	Sarc9371	bone	COSMIC	PRTTPKFS	DEG_SCF_FBW7_1	11503:11510	Mutation rewiring degron network	0.1111
p.A1011P	ACH-002834	Bone Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	1004:1008	Mutation rewiring degron network	0.25
p.T8679P	LS-1034	large intestine	COSMIC	ATTST	DEG_SPOP_SBC_1	8677:8681	Mutation altering degron motif	0.7031
p.L7096P	SK-NEP-1	kidney	COSMIC	PATTS	DEG_SPOP_SBC_1	7103:7107	Mutation rewiring degron network	0.1389
p.V9159A	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	PVSST	DEG_SPOP_SBC_1	9158:9162	Mutation altering degron motif	0.5825
p.V11038A	LNCaP-Clone-FGC	prostate	COSMIC	VTSSS	DEG_SPOP_SBC_1	11046:11050	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC16

UniProt ID: Q8WXI7

Entrez ID: 94025

Protein name: Mucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC16 in