DegronMD - P37198(NUP62)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A46D	TCGA-2W-A8YY	CESC	TCGA	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.A46D	DO223732	CESC	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.I214V	TCGA-56-5897	LUSC	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.3056
p.I214V	DO26453	LUSC	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.3056
p.G134D	TCGA-A5-A0G2	UCEC	TCGA	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.1667
p.G134D	TCGA-A5-A0G2	UCEC	TCGA	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.0556
p.G134D	DO41235	UCEC	ICGC	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.1667
p.G134D	DO41235	UCEC	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.0556
p.P137S	TCGA-A6-3807	COAD	TCGA	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.0833
p.P137S	TCGA-A6-3807	COAD	TCGA	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1389
p.P137S	DO9034	COAD	ICGC	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.0833
p.P137S	DO9034	COAD	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1389
p.P192L	TCGA-AA-A01P	COAD	TCGA	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6471
p.P192L	DO8642	COAD	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.6471
p.A223E	TCGA-AA-A01R	COAD	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223E	TCGA-AA-A01R	COAD	TCGA	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.A223E	DO7934	COAD	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223E	DO7934	COAD	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.A212V	TCGA-AB-2828	LAML	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation altering degron motif	0.5825
p.A212V	DO21571	LAML	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation altering degron motif	0.5825
p.T244I	TCGA-AC-A3W5	BRCA	TCGA	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.5966
p.T244I	DO49024	BRCA	ICGC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.5966
p.F44C	TCGA-AP-A1DV	UCEC	TCGA	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.F44C	DO43186	UCEC	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.T165M	TCGA-B5-A3FA	UCEC	TCGA	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.T165M	DO52402	UCEC	ICGC	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.T165M	SIDM00773	Non-Cancerous	GDSC	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.T165M	SIDM00774	Breast Carcinoma	GDSC	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0556
p.T280A	TCGA-BR-8591	STAD	TCGA	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6028
p.T280A	DO233888	GACA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6028
p.T280A	DO47973	STAD	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6028
p.Q204R	TCGA-CC-A5UD	LIHC	TCGA	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1667
p.Q204R	TCGA-CC-A5UD	LIHC	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.2222
p.Q204R	DO219552	LIHC	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1667
p.Q204R	DO219552	LIHC	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.2222
p.T282S	TCGA-CG-4306	STAD	TCGA	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.T282S	DO230343	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.T282S	DO38567	STAD	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.T282S	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.T52R	TCGA-CV-6936	HNSC	TCGA	PATST	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.8987
p.T52R	DO14210	HNSC	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.8987
p.P185H	TCGA-CV-A45Z	HNSC	TCGA	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1389
p.P185H	DO52064	HNSC	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1389
p.P249S	TCGA-CW-5587	KIRC	TCGA	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation rewiring degron network	0.2222
p.P249S	DO19430	KIRC	ICGC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation rewiring degron network	0.2222
p.T128I	TCGA-D1-A103	UCEC	TCGA	AISST	DEG_SPOP_SBC_1	124:128	Mutation altering degron motif	0.7078
p.T128I	DO42312	UCEC	ICGC	AISST	DEG_SPOP_SBC_1	124:128	Mutation altering degron motif	0.7078
p.F142S	TCGA-D1-A17Q	UCEC	TCGA	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.2778
p.F142S	TCGA-D1-A17Q	UCEC	TCGA	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0833
p.F142S	DO41903	UCEC	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.2778
p.F142S	DO41903	UCEC	ICGC	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.0833
p.G218E	TCGA-EB-A3XD	SKCM	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.1944
p.G218E	TCGA-EB-A3XD	SKCM	TCGA	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.0556
p.G218E	DO37871	SKCM	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.1944
p.G218E	DO37871	SKCM	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.0556
p.P137L	TCGA-EE-A2MR	SKCM	TCGA	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.0833
p.P137L	TCGA-EE-A2MR	SKCM	TCGA	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1389
p.P137L	DO37819	SKCM	ICGC	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.0833
p.P137L	DO37819	SKCM	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1389
p.G58C	TCGA-ER-A196	SKCM	TCGA	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.G58C	DO47474	SKCM	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.2222
p.A212T	TCGA-EY-A215	UCEC	TCGA	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation altering degron motif	0.6028
p.A212T	DO42665	UCEC	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation altering degron motif	0.6028
p.T288A	DO230346	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.1944
p.S283T	DO229010	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.S283T	DO229016	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.S283T	DO229003	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.S283T	DO229005	COCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.S283T	DO230999	LUSC	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.S283T	DO231049	LUSC	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.6005
p.G139S	DO229016	COCA	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	DO229047	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	DO230934	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	DO231169	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00376	B-Lymphoblastic Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00338	Acute Myeloid Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01265	Plasma Cell Myeloma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00570	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00373	Endometrial Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00993	Plasma Cell Myeloma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00557	Neuroblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00617	Hepatocellular Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00572	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01203	Other Solid Cancers	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00611	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00075	Non-Cancerous	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00535	Chondrosarcoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00304	Ovarian Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00602	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00496	Thyroid Gland Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00553	Acute Myeloid Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00267	Biliary Tract Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01242	Melanoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00590	Oral Cavity Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00598	Squamous Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00394	Cervical Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00356	Non-Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00260	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00568	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00282	Colorectal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00235	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01118	Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00054	Pancreatic Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00292	Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00819	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00459	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00250	Esophageal Squamous Cell Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00252	Biliary Tract Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00048	Non-Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00133	Non-Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00502	B-Lymphoblastic Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00240	Cervical Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00247	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00357	Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00347	Esophageal Squamous Cell Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00539	Esophageal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00574	Glioblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00283	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00876	Non-Cancerous	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00970	Bladder Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00988	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00566	Oral Cavity Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00613	Glioblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00877	Breast Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00996	Thyroid Gland Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00233	T-Lymphoblastic Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00503	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01018	Hodgkin's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00808	Burkitt's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01608	Endometrial Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01659	Kidney Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01735	Biliary Tract Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01570	Ovarian Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00168	Head and Neck Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01577	Plasma Cell Myeloma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01444	Glioblastoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01472	Hepatocellular Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00248	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01445	Gastric Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01691	Chronic Myelogenous Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00173	Head and Neck Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01685	B-Lymphoblastic Leukemia	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00823	Colorectal Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01764	Non-Small Cell Lung Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01473	Plasma Cell Myeloma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01451	Pancreatic Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM00162	Biliary Tract Carcinoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.G139S	SIDM01254	Burkitt's Lymphoma	GDSC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.1944
p.T276N	DO223058	ESCA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.25
p.T281A	DO233109	GACA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.825
p.T281A	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.825
p.T281A	ACH-000717	Esophageal Cancer	CCLE	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.825
p.G143D	DO233259	GACA	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.3056
p.G143D	DO233259	GACA	ICGC	PATTS	DEG_SPOP_SBC_1	151:155	Mutation rewiring degron network	0.1111
p.A275D	DO228952	LICA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2222
p.P182T	DO228974	LICA	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.0556
p.T57N	DO228974	LICA	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.25
p.A124D	DO228971	LICA	ICGC	AISST	DEG_SPOP_SBC_1	124:128	Mutation altering degron motif	0.7793
p.T54N	DO228986	LICA	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation altering degron motif	0.7055
p.T234N	DO229031	LICA	ICGC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation rewiring degron network	0.1944
p.T234N	DO229031	LICA	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.2778
p.T187K	DO229035	LICA	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.1944
p.T281I	DO229052	LICA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.8189
p.G201V	DO229053	LICA	ICGC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation rewiring degron network	0.25
p.G201V	DO229053	LICA	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.1389
p.L292F	DO27811	MALY	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.0833
p.G289D	DO27779	MALY	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.1667
p.F140L	DO232846	NACA	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation rewiring degron network	0.2222
p.G289S	DO232858	NACA	ICGC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.1667
p.A212G	DO233293	NACA	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation altering degron motif	0.6429
p.I225M	DO233295	NACA	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.25
p.A223V	DO233294	NACA	ICGC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223V	DO233294	NACA	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.A223V	SIDM00217	Colorectal Carcinoma	GDSC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223V	SIDM00217	Colorectal Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.A223V	ACH-000999	Colon/Colorectal Cancer	CCLE	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223V	ACH-000999	Colon/Colorectal Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.A223V	SNU-1040	large intestine	COSMIC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0556
p.A223V	SNU-1040	large intestine	COSMIC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1944
p.T227I	DO233299	NACA	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.3056
p.A226P	DO233299	NACA	ICGC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.2778
p.F60C	DO33264	PACA	ICGC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.T253A	DO229253	THCA	ICGC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation rewiring degron network	0.1111
p.T146N	DO229250	THCA	ICGC	PSTTS	DEG_SPOP_SBC_1	144:148	Mutation altering degron motif	0.7055
p.F60L	SIDM02041	Colorectal Carcinoma	GDSC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1667
p.A279T	SIDM01943	Colorectal Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.7139
p.A279T	SIDM00747	Non-Small Cell Lung Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.7139
p.A279T	SIDM01752	Pancreatic Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.7139
p.A251T	SIDM02023	Pancreatic Carcinoma	GDSC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation rewiring degron network	0.1667
p.T194M	SIDM00421	T-Cell Non-Hodgkin's Lymphoma	GDSC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7423
p.T194M	ACH-000226	Lymphoma	CCLE	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7423
p.T194M	SUP-M2	haematopoietic and lymphoid tissue	COSMIC	PATPAAT	DEG_SCF_FBW7_1	192:198	Mutation altering degron motif	0.7423
p.S216N	SIDM00491	Thyroid Gland Carcinoma	GDSC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.25
p.S216N	ACH-001443	Thyroid Cancer	CCLE	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.25
p.S216N	ASH-3	thyroid	COSMIC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.25
p.T287S	SIDM00602	Gastric Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2222
p.C240R	SIDM01162	Kidney Carcinoma	GDSC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.719
p.C240R	ACH-001398	Kidney Cancer	CCLE	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.719
p.C240R	SW156	kidney	COSMIC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.719
p.T245I	SIDM00373	Endometrial Carcinoma	GDSC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.7078
p.T245I	ACH-000974	Endometrial/Uterine Cancer	CCLE	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.7078
p.T245I	SNG-M	endometrium	COSMIC	LCTPVTT	DEG_SCF_FBW7_1	239:245	Mutation altering degron motif	0.7078
p.A277V	SIDM00217	Colorectal Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2778
p.A277V	ACH-000999	Colon/Colorectal Cancer	CCLE	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2778
p.F222S	SIDM00785	Acute Myeloid Leukemia	GDSC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0833
p.F222S	SIDM00785	Acute Myeloid Leukemia	GDSC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1667
p.F222S	KG-1	haematopoietic and lymphoid tissue	COSMIC	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.0833
p.F222S	KG-1	haematopoietic and lymphoid tissue	COSMIC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1667
p.A275V	SIDM01617	Endometrial Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2222
p.A275V	ACH-000994	Endometrial/Uterine Cancer	CCLE	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation rewiring degron network	0.2222
p.I225V	SIDM01387	Small Cell Lung Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.25
p.I225V	ACH-000921	Lung Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.25
p.S283N	SIDM01587	Bladder Carcinoma	GDSC	ATTTS	DEG_SPOP_SBC_1	279:283	Mutation altering degron motif	0.7069
p.N120Y	ACH-000831	Endometrial/Uterine Cancer	CCLE	AISST	DEG_SPOP_SBC_1	124:128	Mutation rewiring degron network	0.2222
p.F42V	ACH-000971	Colon/Colorectal Cancer	CCLE	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.1111
p.L221F	ACH-001521	Skin Cancer	CCLE	PTPTAT	DEG_SCF_FBW7_1	208:213	Mutation rewiring degron network	0.1111
p.L221F	ACH-001521	Skin Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	228:232	Mutation rewiring degron network	0.1389
p.T64P	SJSA-1	bone	COSMIC	PATST	DEG_SPOP_SBC_1	50:54	Mutation rewiring degron network	0.0556

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NUP62

UniProt ID: P37198

Entrez ID: 23636

Protein name: Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NUP62 in