DegronMD - Q9Y618(NCOR2)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K1787Q	TCGA-19-5956	GBM	TCGA	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.3056
p.P122S	TCGA-43-2578	LUSC	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1111
p.P122S	DO26662	LUSC	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1111
p.L1785F	TCGA-75-5126	LUAD	TCGA	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.25
p.E608D	TCGA-86-7955	LUAD	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1389
p.R1537W	TCGA-A6-2686	COAD	TCGA	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.1389
p.R1537W	TCGA-G4-6588	COAD	TCGA	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.1389
p.T797A	TCGA-A6-5665	COAD	TCGA	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation altering degron motif	0.7139
p.T597I	TCGA-A8-A09B	BRCA	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.7078
p.T597A	TCGA-A8-A09B	BRCA	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.7139
p.S592N	TCGA-AJ-A23O	UCEC	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.2222
p.R119Q	TCGA-AP-A0LM	UCEC	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1944
p.R119Q	DO43306	UCEC	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1944
p.K97T	TCGA-AZ-4315	COAD	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation substituting flanking lysine	0.1944
p.K97T	DO8842	COAD	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation substituting flanking lysine	0.1944
p.E608A	TCGA-BR-6452	STAD	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1389
p.Q599H	TCGA-BR-6452	STAD	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.647
p.S1792F	TCGA-CC-A3MA	LIHC	TCGA	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation altering degron motif	0.7982
p.T803I	TCGA-DX-AB2V	SARC	TCGA	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation blocking phosphorylation signal	0.7222
p.S1794F	TCGA-EE-A182	SKCM	TCGA	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation blocking phosphorylation signal	0.7222
p.S1794F	TCGA-FW-A3TU	SKCM	TCGA	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation blocking phosphorylation signal	0.7222
p.P785L	TCGA-EE-A2MS	SKCM	TCGA	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.7582
p.R107H	TCGA-EO-A22U	UCEC	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107H	TCGA-VQ-AA6D	STAD	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107H	DO233624	GACA	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107H	DO222392	STAD	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107H	DO43755	UCEC	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107H	ACH-000995	Leukemia	CCLE	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8244
p.R107C	TCGA-EO-A3AZ	UCEC	TCGA	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8301
p.R107C	DO50078	UCEC	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.8301
p.G777R	TCGA-FI-A2D0	UCEC	TCGA	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1944
p.G777R	SIDM00793	Burkitt's Lymphoma	GDSC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1944
p.G777R	EB-3	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1944
p.E611K	TCGA-NJ-A4YP	LUAD	TCGA	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.0556
p.T596I	DO1653	BRCA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.7078
p.T596A	DO1653	BRCA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.7139
p.E1799D	DO2020	BRCA	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1389
p.T779A	DO9756	COAD	ICGC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.K1520T	DO233731	GACA	ICGC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.1667
p.M100I	DO233944	GACA	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1667
p.R1177W	DO10880	GBM	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1944
p.R1798W	DO44615	LGG	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1667
p.P1180T	DO228978	LICA	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.2778
p.A604D	DO229019	LICA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.25
p.P1177H	DO229035	LICA	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1944
p.S591R	DO229006	LICA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1944
p.S1782F	DO23058	LIHC	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1667
p.E610K	DO218943	LUAD	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.0833
p.E607D	DO23612	LUAD	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1667
p.P802A	DO26240	LUAD	ICGC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.3056
p.E807K	DO26818	LUSC	ICGC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation blocking phosphorylation signal	0.6111
p.D1797E	DO52671	MALY	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1944
p.E1785K	DO222868	MELA	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.25
p.A1199D	DO27893	ORCA	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.0556
p.A787G	DO46606	OV	ICGC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.754
p.E111A	DO232761	PBCA	ICGC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.659
p.R1186C	DO51407	PRAD	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.8301
p.R1186C	DO41133	UCEC	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.8301
p.T785I	DO220093	SARC	ICGC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.7078
p.P802S	DO37843	SKCM	ICGC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.3056
p.L1518R	DO48665	SKCM	ICGC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation blocking phosphorylation signal	0.5556
p.R1796L	DO47665	SKCM	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.2222
p.A1530T	DO48547	STAD	ICGC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation altering degron motif	0.7139
p.E607A	DO38404	STAD	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1667
p.Q598H	DO38404	STAD	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.7582
p.Q598K	DO229253	THCA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.6944
p.P1526S	DO229264	THCA	ICGC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation altering degron motif	0.6752
p.T776P	DO229268	THCA	ICGC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1667
p.A601V	DO229268	THCA	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation altering degron motif	0.6936
p.I1189V	DO229240	THCA	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.7076
p.G1179E	DO229088	THCA	ICGC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.25
p.S591N	DO43290	UCEC	ICGC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1944
p.R1796W	DO41584	UCEC	ICGC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.2222
p.S1518T	SIDM00672	Hepatocellular Carcinoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation blocking phosphorylation signal	0.5556
p.S1518T	SIDM00181	Bladder Carcinoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation blocking phosphorylation signal	0.5556
p.S1518T	SIDM01709	Melanoma	GDSC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation blocking phosphorylation signal	0.5556
p.K106Q	SIDM00578	Neuroblastoma	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.5833
p.K106Q	ACH-000804	Neuroblastoma	CCLE	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation altering degron motif	0.5833
p.V1186M	SIDM00422	Hodgkin's Lymphoma	GDSC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.7208
p.G804R	SIDM00098	Mesothelioma	GDSC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.25
p.G804R	ACH-002129	Lung Cancer	CCLE	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.25
p.R1175Q	SIDM00527	Colorectal Carcinoma	GDSC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1389
p.R1175Q	ACH-000935	Colon/Colorectal Cancer	CCLE	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1389
p.P791L	SIDM01102	Non-Cancerous	GDSC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.P791L	SIDM01102	Non-Cancerous	GDSC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.P791L	ACH-002316	Non-Cancerous	CCLE	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.P791L	ACH-002316	Non-Cancerous	CCLE	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.P791L	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.P791L	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.S105G	SIDM00574	Glioblastoma	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.3056
p.S105G	SIDM00616	Hepatocellular Carcinoma	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.3056
p.S105G	SIDM01033	Bladder Carcinoma	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.3056
p.S105G	SIDM01695	Acute Myeloid Leukemia	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.3056
p.S105G	SIDM01442	Glioma	GDSC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.3056
p.E1191K	SIDM00006	Other Solid Cancers	GDSC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.2778
p.E1191K	ACH-001552	Skin Cancer	CCLE	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.2778
p.E1191K	MCC26	skin	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.2778
p.P785T	SIDM01059	Melanoma	GDSC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.7031
p.P785T	ACH-000915	Skin Cancer	CCLE	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.7031
p.P785T	IPC-298	skin	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation altering degron motif	0.7031
p.R1524H	ACH-000748	Bone Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.2778
p.R1524H	ACH-000800	Lung Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.2778
p.P798L	ACH-000860	Lung Cancer	CCLE	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation altering degron motif	0.7582
p.A1526T	ACH-000885	Ovarian Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation altering degron motif	0.7139
p.V1530L	ACH-000892	Lung Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation altering degron motif	0.6765
p.S1518L	ACH-000936	Ovarian Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation blocking phosphorylation signal	0.5556
p.L124V	ACH-000943	Colon/Colorectal Cancer	CCLE	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.0556
p.R1524C	ACH-000990	Endometrial/Uterine Cancer	CCLE	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.2778
p.E795K	ACH-001369	Ovarian Cancer	CCLE	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1389
p.E795K	ACH-001369	Ovarian Cancer	CCLE	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.3056
p.G777E	ACH-002023	Colon/Colorectal Cancer	CCLE	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1944
p.A1195S	MHH-NB-11	autonomic ganglia	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1667
p.P1172H	LS-411N	large intestine	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.0556
p.R774H	RKN	ovary	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1111
p.R774H	ME-1	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1111
p.R774H	BFTC-909	kidney	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1111
p.R774H	TC-YIK	cervix	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1111
p.R774H	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.1111
p.G1195A	GR-ST	haematopoietic and lymphoid tissue	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1667
p.Y1791H	SNU-C5	large intestine	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation altering degron motif	0.7229
p.E1181K	MCC26	skin	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.3056
p.R1794W	KMS-11	haematopoietic and lymphoid tissue	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation blocking phosphorylation signal	0.7222
p.R1794W	GOTO	autonomic ganglia	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation blocking phosphorylation signal	0.7222
p.P773L	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.0833
p.R1783Q	CAL-39	vulva	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation blocking phosphorylation signal	0.6389
p.R791H	ME-1	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.R791H	ME-1	haematopoietic and lymphoid tissue	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R791H	TC-YIK	cervix	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.R791H	TC-YIK	cervix	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R791H	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.R791H	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R791H	BFTC-909	kidney	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.R791H	BFTC-909	kidney	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R791H	RKN	ovary	COSMIC	PPTPPPE	DEG_SCF_FBW7_2	782:788	Mutation rewiring degron network	0.25
p.R791H	RKN	ovary	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R1181W	SW684	soft tissue	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.3056
p.P1194L	TE-11	oesophagus	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation rewiring degron network	0.1944
p.E797K	SNU-81	large intestine	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation altering degron motif	0.7022
p.A1540T	23132-87	stomach	COSMIC	APVIV	DEG_Kelch_actinfilin_1	1526:1530	Mutation rewiring degron network	0.0556
p.L1188M	CW-2	large intestine	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.711
p.E100K	GP5d	large intestine	COSMIC	KRPRLELLP	DEG_APCC_DBOX_1	106:114	Mutation rewiring degron network	0.1667
p.G806S	ETK-1	biliary tract	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.1944
p.R802C	U031	kidney	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.3056
p.G1188S	RCC-ER	kidney	COSMIC	ESLGVPTA	DEG_COP1_1	1182:1189	Mutation altering degron motif	0.6993
p.R1800Q	CAL-39	vulva	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1111
p.V605M	Jurkat	haematopoietic and lymphoid tissue	COSMIC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.2222
p.L803F	SNU-175	large intestine	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation blocking phosphorylation signal	0.7222
p.L803F	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation blocking phosphorylation signal	0.7222
p.E609K	MCF7	breast	COSMIC	ITPQQS	DEG_SCF_FBW7_1	596:601	Mutation rewiring degron network	0.1111
p.S1800I	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PTTTS	DEG_SPOP_SBC_1	1788:1792	Mutation rewiring degron network	0.1111
p.R805H	CML-T1	haematopoietic and lymphoid tissue	COSMIC	PTPASE	DEG_SCF_FBW7_2	796:801	Mutation rewiring degron network	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NCOR2

UniProt ID: Q9Y618

Entrez ID: 9612

Protein name: Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for NCOR2 in