| Tag | Content |
|---|---|
| Uniprot ID | A0A096MIX7 |
| Entrez ID | 367944 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_006257586.3 |
| Ensembl protein ID | ENSRNOP00000067915 |
| Ensembl nucleotide ID | ENSRNOG00000000861 |
| Gene name | Zic family member 3 |
| Gene symbol | Zic3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTMLLDGSPQ FPGLGVGSFG APRHHEMPNR EPAAMGLNPF GDSTHAAAAA AAAAAFKLSP 60 ATAHDLSSGQ SSAFTPQGSG YANALGHHHH HHHHHHASQV PTYGGAASAA FNSTRDFLFR 120 QRGSGLSEAA SGGGQHGLFA GSASSLHAPA GIPEPPSYLL FPGLHEQGAG HPSPTGHVDN 180 NQVHLGLRGE LFGRADPYRP VASPRTDPYA ASAQFPNYSP MNMNMGVNVA AHHGPGAFFR 240 YMRQPIKQEL SCKWIEEAQL SRPKKSCDRT FSTMHELVTH VTMEHVGGPE QNNHVCYWEE 300 CPREGKSFKA KYKLVNHIRV HTGEKPFPCP FPGCGKIFAR SENLKIHKRT HTGEKPFKCE 360 FEGCDRRFAN SSDRKKHMHV HTSDKPYICK VCDKSYTHPS SLRKHMKVHE SQGSDSSPAA 420 SSGYESSTPP AIASANSKDT TKTPSAVQTS TSHNPGLPPN FNEWYV 466 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZIC3 | 541035 | E1BJR9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 492171 | E2R969 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 102177783 | A0A452FJL7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 7547 | O60481 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 22773 | Q62521 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ZIC3 | 740302 | A0A2I3RP19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100156863 | F1RQ88 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100347605 | G1TFC7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 367944 | A0A096MIX7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | zic3 | 368263 | Q6PV84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0007417 | central nervous system development |
| GO:0071907 | determination of digestive tract left/right asymmetry |
| GO:0035545 | determination of left/right asymmetry in nervous system |
| GO:0007368 | determination of left/right symmetry |
| GO:0071910 | determination of liver left/right asymmetry |
| GO:0035469 | determination of pancreatic left/right asymmetry |
| GO:0001947 | heart looping |
| GO:0030324 | lung development |
| GO:0007389 | pattern specification process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0006357 | regulation of transcription by RNA polymerase II |