| Tag | Content |
|---|---|
| Uniprot ID | E1BJR9 |
| Entrez ID | 541035 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001192813.1 |
| Ensembl protein ID | ENSBTAP00000028546 |
| Ensembl nucleotide ID | ENSBTAG00000021413 |
| Gene name | Uncharacterized protein |
| Gene symbol | ZIC3 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTMLLDGGPQ FPGLGVGSFG APRHHEMPNR EPAGIGLTPF GDSPHAAAAA AAAFKLSPAA 60 AHDLSSGQSS AFTPQGSGYA NALGHHHHHH HHHHHAGQVP SYGGAASAAF NSTRDFLFRQ 120 RGSGLGEAAS GGGQHGLFAG SASSLHAPAG ISEPPGYLLF PGLHDQGAGH PSPTGHVDNN 180 QVHLGLRGEL FGRADPYRPV ASPRTDPYTA GAQFPNYSPM NMNMGVNVAA HHGPGAFFRY 240 MRQPIKQELS CKWIDEAQLS RPKKSCDRTF STMHELVTHV TMEHVGGPEQ NNHVCYWEEC 300 PREGKSFKAK YKLVNHIRVH TGEKPFPCPF PGCGKIFARS ENLKIHKRTH TGEKPFKCEF 360 EGCDRRFANS SDRKKHMHVH TSDKPYICKV CDKSYTHPSS LRKHMKVHES QGSDSSPAAS 420 SGYESSTPPA IASANSKDTT KTPSAVQTST SHNPGLPPNF NEWYV 465 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZIC3 | 541035 | E1BJR9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 492171 | E2R969 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 102177783 | A0A452FJL7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 7547 | O60481 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 22773 | Q62521 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ZIC3 | 740302 | A0A2I3RP19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100156863 | F1RQ88 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100347605 | G1TFC7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 367944 | A0A096MIX7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | zic3 | 368263 | Q6PV84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0007417 | central nervous system development |
| GO:0071907 | determination of digestive tract left/right asymmetry |
| GO:0035545 | determination of left/right asymmetry in nervous system |
| GO:0071910 | determination of liver left/right asymmetry |
| GO:0035469 | determination of pancreatic left/right asymmetry |
| GO:0001947 | heart looping |
| GO:0030324 | lung development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |