| Tag | Content |
|---|---|
| Uniprot ID | F1RQ88 |
| Entrez ID | 100156863 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001927742.5 |
| Ensembl protein ID | ENSSSCP00000013508 |
| Ensembl nucleotide ID | ENSSSCG00000012705 |
| Gene name | Zic family member 3 |
| Gene symbol | ZIC3 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTMLLDGGPQ FPGLGVGSFG APRHHEMPNR EPAGMGLNPF GDSPHAAAAA AAAAAFKLSP 60 AAAHDLSSGQ SSAFTPQGSG YANALGHHHH HHHHHHHAGQ VPSYGGAASA AFNSTRDFLF 120 RQRGSGLGEA ASGSGQHGLF AGSASSLHAP AGIPEPPGYL LFPGLHEQGA GHPSPTGHVD 180 NNQVHLGLRG ELFGRADPYR PVASPRTDPY TAGAQFPNYS PMNMNMGVNV AAHHGPGAFF 240 RYMRQPIKQE LSCKWIDEAQ LSRPKKSCDR TFSTMHELVT HVTMEHVGGP EQNNHVCYWE 300 ECPREGKSFK AKYKLVNHIR VHTGEKPFPC PFPGCGKIFA RSENLKIHKR THTGEKPFKC 360 EFEGCDRRFA NSSDRKKHMH VHTSDKPYIC KVCDKSYTHP SSLRKHMKVH ESQGSDSSPA 420 ASSGYESSTP PAIASANSKD TTKTPSAVQT STSHNPGLPP NFNEWYV 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZIC3 | 541035 | E1BJR9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 492171 | E2R969 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 102177783 | A0A452FJL7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 7547 | O60481 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 22773 | Q62521 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ZIC3 | 740302 | A0A2I3RP19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100156863 | F1RQ88 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100347605 | G1TFC7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 367944 | A0A096MIX7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | zic3 | 368263 | Q6PV84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0007417 | central nervous system development |
| GO:0071907 | determination of digestive tract left/right asymmetry |
| GO:0035545 | determination of left/right asymmetry in nervous system |
| GO:0071910 | determination of liver left/right asymmetry |
| GO:0035469 | determination of pancreatic left/right asymmetry |
| GO:0001947 | heart looping |
| GO:0030324 | lung development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |