| Tag | Content |
|---|---|
| Uniprot ID | E2R969 |
| Entrez ID | 492171 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_549291.5 |
| Ensembl protein ID | ENSCAFP00000028008 |
| Ensembl nucleotide ID | ENSCAFG00000018979 |
| Gene name | Zic family member 3 |
| Gene symbol | ZIC3 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTMLLDGGPQ FPGLGVGSFG APRHHEMPNR EPAGMGLNPF GDSPHAAAAA AAAAFKLSPA 60 AAHDLSSGQS SAFTPQGSGY ANALGHHHHH HHHHHHAGQV PSYGGAASAA FNSTRDFLFR 120 QRGSGLGEAA SGGGQHGLFA GSASSLHAPA GIPEPPGYLL FPGLHEQGAG HPSPTGHVDN 180 NQVHLGLRGE LFGRADPYRP VASPRTDPYT AGAQFPNYSP MNMNMGVNVA AHHGPGAFFR 240 YMRQPIKQEL SCKWIDEAQL SRPKKSCDRT FSTMHELVTH VTMEHVGGPE QNNHVCYWEE 300 CPREGKSFKA KYKLVNHIRV HTGEKPFPCP FPGCGKIFAR SENLKIHKRT HTGEKPFKCE 360 FEGCDRRFAN SSDRKKHMHV HTSDKPYICK VCDKSYTHPS SLRKHMKVHE SQGSDSSPAA 420 SSGYESSTPP AIASANSKDT TKTPSAVQTS TSHNPGLPPN FNEWYV 466 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZIC3 | 541035 | E1BJR9 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 492171 | E2R969 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 102177783 | A0A452FJL7 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 7547 | O60481 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 22773 | Q62521 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ZIC3 | 740302 | A0A2I3RP19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100156863 | F1RQ88 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ZIC3 | 100347605 | G1TFC7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Zic3 | 367944 | A0A096MIX7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | zic3 | 368263 | Q6PV84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0007417 | central nervous system development |
| GO:0071907 | determination of digestive tract left/right asymmetry |
| GO:0035545 | determination of left/right asymmetry in nervous system |
| GO:0071910 | determination of liver left/right asymmetry |
| GO:0035469 | determination of pancreatic left/right asymmetry |
| GO:0001947 | heart looping |
| GO:0030324 | lung development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |