| Tag | Content |
|---|---|
| Uniprot ID | A0A287A263 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000038025 |
| Ensembl nucleotide ID | ENSSSCG00000028225 |
| Gene name | Dicer 1, ribonuclease III |
| Gene symbol | DICER1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKSPALQPLS MAGLQLMTPA SSPMGPFFGL PWQQEAIHDN IYTPRKYQVE LLEAALDHNT 60 IVCLNTGSGK TFIAVLLTKE LSYQIRGDFN RNGKRTVFLV NSANQVAQQV SAVRTHSDLK 120 VGEYSNLEVN ASWTKEKWNQ EFTKHQVLVM TCSVALNVLK NGYLALSDIN LLVFDECHLA 180 ILDHPYREIM KLCENCPSCP RILGLTASIL NGKCDPEELE EKIQKLEKIL KSNAETATDL 240 VVLDRYTSQP CEIVVDCGPF TDRSGLYERL LMELEEALNF INDCNIAVHS KERDSTLISK 300 QILSDCRAVL VVLGPWCADK VAGMMVRELQ KYIKHEQEEL HRKFLLFTDT FLRKVHALCE 360 GHFSPAALDL RFVTPKVIKL LEILRKYKPY ERQQFESVEW YNNRNQDNYV SWSDSEDDEE 420 DEEIEEKEKP ETNFPSPFTN ILCGIIFVER RYTAVVLNRL IKEAGKQDPE LAYISSNFIT 480 GHGIGKNQPR NKQMEAEFRK QEEVLRKFRA HETNLLIATS IVEEGVDIPK CNLVVRFDLP 540 TEYRSYVQSK GRARAPISNY VMLADTDKIK SFEEDLKTYK AIEKILRNKC SKSVESGETD 600 LEPVVDDDDI FPPYVLRPDD GGPRVTINTA IGHINRYCAR LPSDPFTHLA PKCRTRELPD 660 GTFYSTLYLP INSPLRASIV GPPMSCIRLA ERVVALICCE KLHKIGELDD HLMPVGKETV 720 KYEEELDLHD EEETSVPGRP GSTKRRQCYP KAIPECLRDS YPKPDQPCYL YVIGMVLTTP 780 LPDELNFRRR KLYPPEDTTR CFGILTAKPI PQIPHFPVYT RSGEVTISIE LKKSGFTLSL 840 QMLELITRLH QYIFSHILRL EKPALEFKPT DADSAYCVLP LNVVNDSSTL DIDFKFMEDI 900 EKSEARIGIP STKYSKETPF VFKLEDYQDA VIIPRYRNFD QPHRFYVADV YTDLTPLSKF 960 PSPEYETFAE YYKTKYNLDL TNLNQPLLDV DHTSSRLNLL TPRHLNQKGK ALPLSSAEKR 1020 KAKWESLQNK QILVPELCAI HPIPASLWRK AVCLPSILYR LHCLLTAEEL RAQTASDAGV 1080 GVRSLPVDFR YPNLDFGWKK SIDSKSFISV ANSSSAENEN YCKHSPLVPE HAAHRGANRP 1140 SALENHGHTS VTCRALLSES PAKLPIDVAT DLTAVNGLSY NKNLANGSYD LANRDFCQGN 1200 HLSYYKQEIP VQPTTSYPIQ NLYNYENQPQ PSDECTLLSN KYLDGNANKS TSEGRPTMPG 1260 TTEAGKALSE RMASAQSPAP GYSPRTLGPN PGLILQALTL SNASDGFNLE RLEMLGDSFL 1320 KHAITTYLFC TYPDAHEGRL SYMRSKKTKD CVLANGRLDA DLEEEDAAAL MWRPPREEAE 1380 DDEDLLEYDQ EHIRFIDSML MGSGAFVKKI ALAPFAAADP AYEWKMPKKA PLGSMPFSAD 1440 FEDFDYSSWD AMCYLDPSKA VEEDDFVVGF WNPSEENCGV DTGKQSISYD LHTEQCIADK 1500 SIADCVEALL GCYLTSCGER AAQLFLCSLG LKVLPAVKRT DRAQAACPAR ESFTSQQKTL 1560 SGGRPAAGSR SSGLKDLEYG CLKIPPRCMF DHPDADRTLS HLISGFENFE RKINYSFKNK 1620 AYLLQAFTHA SYHYNTITDC YQRLEFLGDA ILDYLITKHL YEDPRQHSPG VLTDLRSALV 1680 NNTIFASLAV KYDYHKYFKA VSPELFHVID DFVQFQLEKN EMQGMDSELR RSEEDEEKEE 1740 DIEVPKAMGD IFESLAGAIY MDSGMSLEVV WQVYYPMMRP LIEKFSANVP RSPVRELLEM 1800 EPETAKFSPA ERTYDGKVRV TVEVVGKGKF KGVGRSYRIA KSAAARRALR SLKANQPQSI 1860 FIWTSTTI 1868 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DICER1 | 480426 | E2RIN4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | DICER1 | 102175335 | A0A452ESG3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | DICER1 | 23405 | Q9UPY3 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Dicer1 | Q8R418 | CPO | Mus musculus | Publication | More>> | ||
| 1:1 ortholog | DICER1 | 453137 | H2R458 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DICER1 | A0A287A263 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Dicer1 | 299284 | E9PU15 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dicer1 | 324724 | Q6TV19 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005524 | ATP binding |
| GO:0004525 | ribonuclease III activity |
| GO:0003723 | RNA binding |
| GO:0031047 | gene silencing by RNA |
| GO:0006396 | RNA processing |