| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8J1H0; A0A2I3RY31; |
| Entrez ID | 450857 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016919688.1 |
| Ensembl protein ID | ENSPTRP00000069232 |
| Ensembl nucleotide ID | ENSPTRG00000003099 |
| Gene name | Cytochrome P450 family 2 subfamily E member 1 |
| Gene symbol | CYP2E1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSALGVTVAL LVWAAFLLLV SMWRQVHSSW NLPPGPFPLP IIGNLFQLEL KNIPKSFTRL 60 AQRFGPVFTL YVGSQRMVVM HGYKAVKEAL LDYKDEFSGR GDLPAFHAHR DRGIIFNNGP 120 TWKDIRRFSL TTLRNYGMGK EGNESRIQRE AHFLLEALRK TQGQPFDPTF LIGCAPCNVI 180 ADILFRKHFD YDDEKFLRLM YLFNENFHLL STPWLQLYNN FPSVLHYLPG SHRKVIKNVA 240 EIKEYVSERV KEHHQSLDPN CPRDLTDCLL VEMEKEKHSA ERLYTMDGIT VTVADLFFAG 300 TETTSTTLRY GLLILMKYPE IEEKLHEEID RVIGPSRIPA IKDRQEMPYM DAVVHEVQRF 360 ITLVPSNLPH EATRDTIFRG YLIPKGTVVV PTLDSVLYDN QEFPDPEKFK PEHFLNENGK 420 FKYSDYFKPF STGKRVCAGE GLARMELFLL LCAILQHFNL KPLVDPKDID LSPIHIGFGC 480 IPPRYKLCVI PRS 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP2E1 | 282213 | Q2TBV4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 415128 | Q9MZY0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 102182294 | A0A452DL40 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 1571 | P05181 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp2e1 | 13106 | Q05421 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 450857 | A0A2J8J1H0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | F1SCT4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cyp2e1 | 25086 | P05182 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |