| Tag | Content |
|---|---|
| Uniprot ID | Q2TBV4 |
| Entrez ID | 282213 |
| Genbank protein ID | AAI09597.1 |
| Genbank nucleotide ID | NM_174530.3 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Cytochrome P450 subfamily IIE polypeptide 1 |
| Gene symbol | CYP2E1 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAALGITVAL LVWMATLLFI SIWKHIYSSW KLPPGPFPLP IIGNLLQLDI KNIPKSFTRL 60 AERYGPVFTL YLGSQRAVVV HGYKPVKEVL LDYKNEFSGR GENPGFQMHK NNGIIFNNGS 120 TWRDTRRFSL TTLRDLGMGK QGNEQRIQRE AHFLLEVLRK TQGQPFDPTF VVGFAPYNVI 180 SDILFHKRFD YKDQTSLRLM SLFNENFYLL SSPWIQLYNN FSDYLQYLPG SHRKLLKNVS 240 EVKSYALERV KDHQKSLEPS CPRGFLDTML IEMAKERHSV DPMYTLENIA VTVADLLFAG 300 TETTSTTLRY GLLILMKYPE VEEKLHEEID RVIGPSRIPA VKDRLDMPYL DAVVHEIQRF 360 IDLLPSNLLH EATQDTVFRG YVIPKGTVVI PTLDSVLHDR QEFPEPEKFK PEHFLNENGK 420 FKYSDHFKAF SAGKRVCVGE GLARMELFLL LAAILQHFNL KSLVDPKDID LSPIAIGFGK 480 IPPRYKLCLI PRSKV 495 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP2E1 | 282213 | Q2TBV4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 415128 | Q9MZY0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 102182294 | A0A452DL40 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 1571 | P05181 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp2e1 | 13106 | Q05421 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 450857 | A0A2J8J1H0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | F1SCT4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cyp2e1 | 25086 | P05182 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0043231 | intracellular membrane-bounded organelle |
| GO:0008392 | arachidonic acid epoxygenase activity |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| GO:0008395 | steroid hydroxylase activity |
| GO:0019373 | epoxygenase P450 pathway |
| GO:0042738 | exogenous drug catabolic process |
| GO:0006082 | organic acid metabolic process |
| GO:0055114 | oxidation-reduction process |
| GO:0006805 | xenobiotic metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |