| Tag | Content |
|---|---|
| Uniprot ID | F1SCT4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000011493 |
| Ensembl nucleotide ID | ENSSSCG00000010780 |
| Gene name | Cytochrome P450 2E1 |
| Gene symbol | CYP2E1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTALGITVAL LVWLVTLLLI SIWKHIHSSW KLPPGPFPLP IVGNIFQLDL KNIPKSFTML 60 AERYGPVFTV YLGSRRIVVL HGYKAVKEVL LHYKNEFSGR GEIPTFQVHK DKGVIFNNGP 120 TWRDTRRFSL TTLRDFGMGK QGNEQRIQRE AHFLLEALRK THGQPFDPTF LIGCAPCNVI 180 SDILFRQHFD YNDKTCLRLM SMFNENFYLL STGWIQLYNN FSGYLRYLPG SHRKLMKNIS 240 EIKDYALERV KDHRDSLEPS CPRDFTDTLL MEMEKEKYSA EPIYTLDNIA VTVADMFFAG 300 TETTSTTLRY GLLILMKYPE VEEKLHEEID RVIGPNRIPA IKDRLDMPYL DAVVHEIQRF 360 IDLIPSNLPH EATRDTVFRD YIIPKGTVVI PTLDSVLYDS QEFPEPEKFK PEHFLNENGK 420 FKYSDHFKAF SAGKRVCVGE GLARMELFLF MAAILQHFNL KSLVDPKDID LSPITIGFAK 480 IPPHYKLCVI PRSQV 495 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | CYP2E1 | 282213 | Q2TBV4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 415128 | Q9MZY0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 102182294 | A0A452DL40 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 1571 | P05181 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Cyp2e1 | 13106 | Q05421 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | 450857 | A0A2J8J1H0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | CYP2E1 | F1SCT4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Cyp2e1 | 25086 | P05182 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016021 | integral component of membrane |
| GO:0043231 | intracellular membrane-bounded organelle |
| GO:0008392 | arachidonic acid epoxygenase activity |
| GO:0020037 | heme binding |
| GO:0005506 | iron ion binding |
| GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| GO:0008395 | steroid hydroxylase activity |
| GO:0019373 | epoxygenase P450 pathway |
| GO:0042738 | exogenous drug catabolic process |
| GO:0006082 | organic acid metabolic process |
| GO:0055114 | oxidation-reduction process |
| GO:0006805 | xenobiotic metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00086 | CYTOCHROME_P450 |
| Pfam ID | Pfam Term |
|---|---|
| PF00067 | p450 |