| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8LIN5; H2QCL1; |
| Entrez ID | 468201 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_009432470.2 |
| Ensembl protein ID | ENSPTRP00000015294 |
| Ensembl nucleotide ID | ENSPTRG00000008958 |
| Gene name | Transporter |
| Gene symbol | SLC6A4 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | METTPLNSQK QLSACEDGED CQENGVLQKV VPTPGDKVES GQISNGYSAV PSPGAGDDTR 60 HSIPAATTTL VAELHQGERE TWGKKVDFLL SVIGYAVDLG NVWRFPYICY QNGGGAFLLP 120 YTIMAIFGGI PLFYMELALG QYHRNGCISI WRKICPIFKG IGYAICIIAF YIASYYNTIM 180 AWALYYLISS FTDQLPWTSC KNSWNTGNCT NYFSEGNITW TLHSTSPAEE FYTRHVLQIH 240 RSKGLQDLGG ISWQLALCIM LIFTVIYFSI WKGVKTSGKV VWVTATFPYI ILSVLLVRGA 300 TLPGAWRGVL FYLKPNWQKL LETGVWIDAA AQIFFSLGPG FGVLLAFASY NKFNNNCYQD 360 ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD AGPSLLFITY AEAIANMPAS 420 TFFAIIFFLM LITLGLDSTF AGLEGVITAV LDEFPHIWAK RREWFVLAVV ITCFFGSLVT 480 LTFGGAYVVK LLEEYATGPA VLTVALIEAV AVSWFYGITQ FCRDVKEMLG FSPGWFWRIC 540 WVAISPLFLL FIICSFLMSP PQLRLFQYNY PYWSIILGYC IGTSSFICIP TYIAYRLIIT 600 PGTFKERIIK SITPETPTEI PCGDIRLNAV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SLC6A4 | 491184 | F1PXA1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 102172383 | A0A452DQ43 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 100033848 | F6QG30 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 6532 | P31645 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Slc6a4 | 15567 | Q60857 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 468201 | A0A2J8LIN5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | G1SK44 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Slc6a4 | 25553 | P31652 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | slc6a4a | 664719 | Q1WGB5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0012505 | endomembrane system |
| GO:0005925 | focal adhesion |
| GO:0005887 | integral component of plasma membrane |
| GO:0045121 | membrane raft |
| GO:0098793 | presynapse |
| GO:0050998 | nitric-oxide synthase binding |
| GO:0005335 | serotonin:sodium symporter activity |
| GO:0048854 | brain morphogenesis |
| GO:0071310 | cellular response to organic substance |
| GO:0046621 | negative regulation of organ growth |
| GO:0045787 | positive regulation of cell cycle |
| GO:0010628 | positive regulation of gene expression |
| GO:0090067 | regulation of thalamus size |
| GO:0009636 | response to toxic substance |
| GO:0035176 | social behavior |