| Tag | Content |
|---|---|
| Uniprot ID | G1SK44 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSOCUP00000003158 |
| Ensembl nucleotide ID | ENSOCUG00000003640 |
| Gene name | Transporter |
| Gene symbol | SLC6A4 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MCGCAPGGAG GEGRAIECAG VRLCMRVRGP SRASAGPGRA RQPPPHTPGA ARGGAAGTQV 60 SRPARDPQRG GGYRAIRPCE GPRVQINRAA RAQLGTGGGR PGASRAPGAR DRPPHALPQQ 120 SSGSWRKEAA RGSVRAAADG RPHRSLSSSM ETTPLNAQPG RSACKDGEDC RGSGVLRKGV 180 AGDKAEPGQL SNGYSGVPGP GAGDDAGHAI LAATTTLEAE AHPGGRETWG KKVDFLLSVI 240 GYAVDLGNVW RFPYICYQNG GGAFLLPYTI MAVFGGIPLF YMELALGQYH RNGCISIWRK 300 ICPIFKGIGF AICIIAFYIA SYYNTIMAWA LYYLISSFTD QLPWTSCENS WNTGNCTNYF 360 SEDNITWTLH STSPAEEFYT RHVLQIHRSK GLQALGGISW QLALCIMLIF TIIYFSIWKG 420 VKTSGKVVWV TATFPYIILS ILLVRGATLP GAWRGVLFYL KPNWQKLLET GVWVDAAAQI 480 FFSLGPGFGV LLAFASYNKF NNNCYQDALV TSVVNCMTSF VSGFVIFTVL GYMAEMRNED 540 VSEVARDAGP SLLFITYAEA IANMPASTFF AIIFFLMLIT LGLDSTFAGL EGVITAVLDE 600 FPHTWAKCRE WFVLLVVITC FFGSLITLTF GGAYVVKLLE EYATGPAVLT VALIEAVAVS 660 WFYGITQFCS DVKEMLGFSP GWFWRICWVA ISPLFLLFII CSFLMSPPQL RLFQYNYPHW 720 SIILGYCIGA SSVICIPTYI IYRLIITPGT FKERIIRSIT PETPTEIPCG DIRLDAV 777 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SLC6A4 | 491184 | F1PXA1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 102172383 | A0A452DQ43 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 100033848 | F6QG30 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 6532 | P31645 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Slc6a4 | 15567 | Q60857 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 468201 | A0A2J8LIN5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | G1SK44 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Slc6a4 | 25553 | P31652 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | slc6a4a | 664719 | Q1WGB5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0012505 | endomembrane system |
| GO:0005925 | focal adhesion |
| GO:0005887 | integral component of plasma membrane |
| GO:0045121 | membrane raft |
| GO:0098793 | presynapse |
| GO:0050998 | nitric-oxide synthase binding |
| GO:0005335 | serotonin:sodium symporter activity |
| GO:0048854 | brain morphogenesis |
| GO:0071310 | cellular response to organic substance |
| GO:0046621 | negative regulation of organ growth |
| GO:0045787 | positive regulation of cell cycle |
| GO:0010628 | positive regulation of gene expression |
| GO:0090067 | regulation of thalamus size |
| GO:0009636 | response to toxic substance |
| GO:0035176 | social behavior |