Tag | Content |
---|---|
Uniprot ID | F1PXA1 |
Entrez ID | 491184 |
Genbank protein ID | |
Genbank nucleotide ID | XM_005624347.1; XM_005624348.2; |
Ensembl protein ID | ENSCAFP00000028028 |
Ensembl nucleotide ID | ENSCAFG00000018990 |
Gene name | Transporter |
Gene symbol | SLC6A4 |
Organism | Canis lupus familiaris |
NCBI taxa ID | 9615 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | |
Sequence | METTALNSQK ELSACKDKED CQENGVLQQG VPVPEDKVES GQISSGYSAV PSPGAGDDPQ 60 HSIPAATTAL VAEVHQGERE AWGKKMDFLL SVIGYAVDLG NVWRFPYICY QNGGGAFLLP 120 YTIMAIFGGI PLFYMELALG QYHRNGCISI WRKICPIFKG IGYAICIIAF YIASYYNTIM 180 AWALYYLISS FTDQLPWTSC KNSWNTGNCT NYFSGDNITW TPHSTSPAEE FYMRHVLQLH 240 RSNGLQDLGG ISWQLTLCIM LIFVVIYFSI WKGVKTSGKV VWVTATFPYI ILSVLLVRGA 300 TLPGAWRGVL FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY NKFNNNCYQD 360 ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD AGPSLLFITY AEAIANMPAS 420 TFFAIIFFLM LITLGLDSTF AGLEGVITAV LDEFPHIWSK RREWFVLCVV ITCFFGSLVT 480 LTFGGAYVVK LLEEYATGPA VLTVALIEAV AVYWFYGITQ FCSDVKEMLG FSPGWFWRIC 540 WVAISPLFLL FIICSFLMSP PQLRLFQYNY PQWSIILGYC IGTSSFICIP TYITYRLVTT 600 PGTFKERIIR GITPETATEI PYGDIHLNAI |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
---|---|---|---|---|---|---|---|---|
1:1 ortholog | SLC6A4 | 491184 | F1PXA1 | Canis lupus familiaris | Prediction | More>> | ||
1:1 ortholog | SLC6A4 | 102172383 | A0A452DQ43 | Capra hircus | Prediction | More>> | ||
1:1 ortholog | SLC6A4 | 100033848 | F6QG30 | Equus caballus | Prediction | More>> | ||
1:1 ortholog | SLC6A4 | 6532 | P31645 | Homo sapiens | Publication | More>> | ||
1:1 ortholog | Slc6a4 | 15567 | Q60857 | Mus musculus | Prediction | More>> | ||
1:1 ortholog | SLC6A4 | 468201 | A0A2J8LIN5 | Pan troglodytes | Prediction | More>> | ||
1:1 ortholog | SLC6A4 | G1SK44 | Oryctolagus cuniculus | Prediction | More>> | |||
1:1 ortholog | Slc6a4 | 25553 | P31652 | Rattus norvegicus | Prediction | More>> | ||
1:1 ortholog | slc6a4a | 664719 | Q1WGB5 | Danio rerio | Prediction | More>> |
GO ID | GO Term |
---|---|
GO:0012505 | endomembrane system |
GO:0005925 | focal adhesion |
GO:0005887 | integral component of plasma membrane |
GO:0045121 | membrane raft |
GO:0043005 | neuron projection |
GO:0005886 | plasma membrane |
GO:0098793 | presynapse |
GO:0050998 | nitric-oxide synthase binding |
GO:0051378 | serotonin binding |
GO:0005335 | serotonin:sodium symporter activity |
GO:0048854 | brain morphogenesis |
GO:0071310 | cellular response to organic substance |
GO:0046621 | negative regulation of organ growth |
GO:0045787 | positive regulation of cell cycle |
GO:0010628 | positive regulation of gene expression |
GO:0090067 | regulation of thalamus size |
GO:0009636 | response to toxic substance |
GO:0051610 | serotonin uptake |
GO:0035176 | social behavior |