| Tag | Content |
|---|---|
| Uniprot ID | A0A452DQ43 |
| Entrez ID | 102172383 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018064359.1 |
| Ensembl protein ID | ENSCHIP00000001845 |
| Ensembl nucleotide ID | ENSCHIG00000003163 |
| Gene name | Transporter |
| Gene symbol | SLC6A4 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | METTPLNSQK ELSAYKDGED CQENGVLQKG VPAPGDKAES GQISNGYSAV PNPGAGDDTQ 60 HSIPAATTAL VAEVYPAERE TWGKKVDFLL SVIGYAVDLG NVWRFPYICY QNGGGAFLLP 120 YTIMAIFGGI PLFYMELALG QYHRNGCISI WTKICPIFKG IGCAICLIAF YIASYYNTIM 180 AWALYYLISS FTEQLPWTSC ENSWNTGNCT NYFSEDNITW MLHSTSPAEE FYTRHVLQIH 240 RSKGLQDLGG LSWQLVLCIM FIFTIIYFSI WKGVKTSGKV VWVTAIFPYI ILLILLVRGA 300 TLPGAWRGVL FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY NKFHNNCYQD 360 ALVTSAVNCM TSFVSGFVIF TVLGYMAEMR KEDVSEVAKD AGPSLLFITY AEAIANMPAS 420 TFFAIVFFLM LITLGLDSTF AGLEGVITAV LDEFPHVWAK RREWFVLGVV ITCFFGSLVT 480 LTFGGAYVVK LLEEFATGPA VLTVALIEAV AVFWFYGINQ FCSDVKEMLG FSPGWFWKIC 540 WVAISPLFLL FIICSFLMSP PQLRLFQYDY PRWSIILGYC IGTSSFICIP TYITYRLIVT 600 PGTLKERIIK GITPETPTEI PCGDIRLNAV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SLC6A4 | 491184 | F1PXA1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 102172383 | A0A452DQ43 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 100033848 | F6QG30 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 6532 | P31645 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Slc6a4 | 15567 | Q60857 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | 468201 | A0A2J8LIN5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SLC6A4 | G1SK44 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Slc6a4 | 25553 | P31652 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | slc6a4a | 664719 | Q1WGB5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0012505 | endomembrane system |
| GO:0005925 | focal adhesion |
| GO:0005887 | integral component of plasma membrane |
| GO:0045121 | membrane raft |
| GO:0098793 | presynapse |
| GO:0050998 | nitric-oxide synthase binding |
| GO:0005335 | serotonin:sodium symporter activity |
| GO:0048854 | brain morphogenesis |
| GO:0071310 | cellular response to organic substance |
| GO:0046621 | negative regulation of organ growth |
| GO:0045787 | positive regulation of cell cycle |
| GO:0010628 | positive regulation of gene expression |
| GO:0090067 | regulation of thalamus size |
| GO:0009636 | response to toxic substance |
| GO:0035176 | social behavior |