Gene: rad23b

Basic information

Tag Content
Uniprot ID A0A2R8PYT0
Entrez ID 393536
Genbank protein ID
Genbank nucleotide ID NM_200564.2
Ensembl protein ID ENSDARP00000145115
Ensembl nucleotide ID ENSDARG00000021550
Gene name UV excision repair protein RAD23
Gene symbol rad23b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Sequence
MQITLKTLQQ QTFKIDIDAE ETVKALKEKI ENEKGKDGFP VAGQKLIYAG KILSDDTALK 60
EYKIDEKNFV VVMVTKPKSA SAPAPPSSSS SSSSSTTASA SAAPSAAPVS ESPSEEEKKP 120
SEEKPSSDPA PATTPVSSGS LPNANIFEEA TSALVTGQSY ENMVTEIMLM GYERDRVVAA 180
LRASFNNPDR AVEYLLTGIP AEGEGSVVGA VDAVSPSGST PASAPAPAIS TGLSSPSSTA 240
PAQPSSASGA NPLEFLRNQP QFLQMRQIIQ QNPSLLPALL QQIGRENPQL LQQISSHQEQ 300
FIQMLNEPVQ EAGQGGGAGG VAEAGGGHMN YIQVTPQEKE AIERLKALGF PEGLVIQAYF 360
ACEKNENLAA NFLLQQNFDD D 381

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRAD23B530189Q29RK4Bos taurusPredictionMore>>
1:1 orthologRAD23B481656E2R4A5Canis lupus familiarisPredictionMore>>
1:1 orthologRAD23B102183790A0A452FP98Capra hircusPredictionMore>>
1:1 orthologRAD23B5887P54727Homo sapiensPredictionMore>>
1:1 orthologRad23b19359P54728CPOMus musculusPublicationMore>>
1:1 orthologRAD23B473012K7BCM9Pan troglodytesPredictionMore>>
1:1 ortholog100153668A0A480DNV8Sus scrofaPredictionMore>>
1:1 orthologRAD23B100353489G1SST9Oryctolagus cuniculusPredictionMore>>
1:1 orthologRad23b298012Q4KMA2Rattus norvegicusPredictionMore>>
1:1 ortholograd23b393536A0A2R8PYT0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005654 nucleoplasm
GO:0000502 proteasome complex
GO:0003684 damaged DNA binding
GO:0031593 polyubiquitin modification-dependent protein binding
GO:0070628 proteasome binding
GO:0043130 ubiquitin binding
GO:0006289 nucleotide-excision repair
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0963 Cytoplasm
KW-0227 DNA damage
KW-0234 DNA repair
KW-0539 Nucleus
KW-0597 Phosphoprotein
KW-0647 Proteasome
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0677 Repeat

Interpro

InterPro ID InterPro Term
IPR004806 Rad23
IPR041811 RAD23A/B_UBA1
IPR006636 STI1_HS-bd
IPR015940 UBA
IPR009060 UBA-like_sf
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf
IPR015360 XPC-bd
IPR036353 XPC-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS50030 UBA
PS50053 UBIQUITIN_2

Pfam

Pfam ID Pfam Term
PF00627 UBA
PF00240 ubiquitin
PF09280 XPC-binding