Gene: RAD23B

Basic information

Tag Content
Uniprot ID G1SST9
Entrez ID 100353489
Genbank protein ID
Genbank nucleotide ID XM_002708127.3
Ensembl protein ID ENSOCUP00000006328
Ensembl nucleotide ID ENSOCUG00000007316
Gene name UV excision repair protein RAD23
Gene symbol RAD23B
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Sequence
MQVTLKTLQQ QTFKIDIDPE ETVKALKEKI ESEKGKDAFP VAGQKLIYAG KILNDDTALK 60
EYKIDEKNFV VVMVTKPKAV TTPAPATTQQ SNSATTTAVS SSTATAVTQA STPAPALAPT 120
STPASIAPAS TTSSEPAPAS ATKQEKPAEK PVETPVATSP TSTDSTSGDS SRSNLFEDAT 180
SALVTGQSYE NMVTEIMSMG YEREQVIAAL RASFNNPDRA VEYLLMGIPG DRESQAVVEP 240
PQAAGTGAPQ SSAVAAGAAT TTATTTTTSS GGHPLEFLRN QPQFQQMRQI IQQNPSLLPA 300
LLQQIGRENP QLLQQISQHQ EHFIQMLNEP VQEAGSQGGG GGGSGNAGIA EAGSGHMNYI 360
QVTPQEKEAI ERLKALGFPE GLVIQAYFAC EKNENLAANF LLQQNFDED 409

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRAD23B530189Q29RK4Bos taurusPredictionMore>>
1:1 orthologRAD23B481656E2R4A5Canis lupus familiarisPredictionMore>>
1:1 orthologRAD23B102183790A0A452FP98Capra hircusPredictionMore>>
1:1 orthologRAD23B5887P54727Homo sapiensPredictionMore>>
1:1 orthologRad23b19359P54728CPOMus musculusPublicationMore>>
1:1 orthologRAD23B473012K7BCM9Pan troglodytesPredictionMore>>
1:1 ortholog100153668A0A480DNV8Sus scrofaPredictionMore>>
1:1 orthologRAD23B100353489G1SST9Oryctolagus cuniculusPredictionMore>>
1:1 orthologRad23b298012Q4KMA2Rattus norvegicusPredictionMore>>
1:1 ortholograd23b393536A0A2R8PYT0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0042025 host cell nucleus
GO:0003684 damaged DNA binding
GO:0006289 nucleotide-excision repair
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0963 Cytoplasm
KW-0227 DNA damage
KW-0234 DNA repair
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR004806 Rad23
IPR041811 RAD23A/B_UBA1
IPR006636 STI1_HS-bd
IPR015940 UBA
IPR009060 UBA-like_sf
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf
IPR015360 XPC-bd
IPR036353 XPC-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS50030 UBA
PS50053 UBIQUITIN_2

Pfam

Pfam ID Pfam Term
PF00627 UBA
PF00240 ubiquitin
PF09280 XPC-binding