| Tag | Content |
|---|---|
| Uniprot ID | E2R4A5 |
| Entrez ID | 481656 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_538778.5 |
| Ensembl protein ID | ENSCAFP00000004125 |
| Ensembl nucleotide ID | ENSCAFG00000002792 |
| Gene name | UV excision repair protein RAD23 |
| Gene symbol | RAD23B |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair. |
| Sequence | MLVTLKTLQQ QTFKIDIDPD ETVKALKEKI ESEKGKDAFP VAGQKLIYAG KILNDDTALK 60 EYKIDEKNFV VVMVTKPKAV TTPAPATTQQ SNPATTTTVS SSTAPTVVQA PAPPVLAPTP 120 SPASVTPAPA TSSEPAPTSV TQQEKPAEKP AETPVATSPT ATDSTSGDSS RSNLFEDATS 180 ALVTGQSYEN MVTEIMSMGY EREQVIAALR ASFNNPDRAV EYLLMGIPGD RESQAVVDTP 240 PAVSTGAPPS SVAAAAATTT ASTTTASPGG HPLEFLRNQP QFQQMRQIIQ QNPSLLPALL 300 QQIGRENPQL LQQISQHQEH FIQMLNEPVQ EAGGQGGGGG GGSGGIAEAG SGHMNYIQVT 360 PQEKEAIERL KALGFPEGLV IQAYFACEKN ENLAANFLLQ QNFDED 406 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RAD23B | 530189 | Q29RK4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 481656 | E2R4A5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 102183790 | A0A452FP98 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RAD23B | 5887 | P54727 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Rad23b | 19359 | P54728 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | RAD23B | 473012 | K7BCM9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100153668 | A0A480DNV8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | RAD23B | 100353489 | G1SST9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Rad23b | 298012 | Q4KMA2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | rad23b | 393536 | A0A2R8PYT0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0042025 | host cell nucleus |
| GO:0005654 | nucleoplasm |
| GO:0071942 | XPC complex |
| GO:0003684 | damaged DNA binding |
| GO:0031593 | polyubiquitin modification-dependent protein binding |
| GO:0070628 | proteasome binding |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043130 | ubiquitin binding |
| GO:0098761 | cellular response to interleukin-7 |
| GO:0000715 | nucleotide-excision repair, DNA damage recognition |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |
| GO:0007283 | spermatogenesis |